Non-targeted HIV testing in the emergency department: not just how but where

References

• Joint United Nations Programme on HIV/AIDS. 90-90-90 An ambitious treatment target to help end the AIDS epidemic. Geneva, Switzerland; 2014 [cited 2018 Sept 28]. Available at: http://www.unaids.org/sites/default/files/media_asset/90-90-90_en.pdf
   Google Scholar
• Joint United Nations Programme on HIV/AIDS. How AIDS changed everything. MDG6: 15 years, 15 lessons of hope from the AIDS response. Geneva, Switzerland: UNAIDS; 2015.
   Google Scholar
• Bradley H, Hall HI, Wolitski RJ, et al. Vital signs: HIV diagnosis, care, and treatment among persons living with HIV – United States, 2011. MMWR. 2014;63(47):1113–1117.
   PubMed Web of Science ®Google Scholar
• Kirwan PD, Chau C, Brown AE, and contributors. HIV in the UK - 2016 report. London: Public Health England; 2016.
   Google Scholar
• Supervie V, Ndawinz JD, Lodi S, et al. The undiagnosed HIV epidemic in France and its implications for HIV screening strategies. AIDS. 2014;28(12):1797–1804.
   PubMed Web of Science ®Google Scholar
• Kohler P, Schmidt AJ, Cavassini M, et al. The HIV care cascade in Switzerland: reaching the UNAIDS/WHO targets for patients diagnosed with HIV. AIDS. 2015;29(18):2509–2515.
   PubMed Web of Science ®Google Scholar
• Skarbinski J, Rosenberg E, Paz-Bailey G, et al. Human immunodeficiency virus transmission at each step of the care continuum in the united states. JAMA Intern Med. 2015;175(4):588–596.
   PubMed Web of Science ®Google Scholar
• Mocroft A, Lundgren JD, Sabin ML, et al. Risk factors and outcomes for late presentation for HIV-positive persons in Europe: results from the Collaboration of Observational HIV Epidemiological Research Europe Study (COHERE). PLoS Med. 2013;10(9):e1001510.
   PubMed Web of Science ®Google Scholar
• Darling KE, Hachfeld A, Cavassini M, et al. Late presentation to HIV care despite good access to health services: current epidemiological trends and how to do better. Swiss Med Wkly. 2016;146:w14348.
   PubMed Web of Science ®Google Scholar
• Hachfeld A, Ledergerber B, Darling K, et al. Reasons for late presentation to HIV care in Switzerland. J Int AIDS Soc. 2015;18(1):20317.
   PubMedGoogle Scholar
• Branson BM, Handsfield HH, Lampe MA, et al. Revised recommendations for HIV testing of adults, adolescents, and pregnant women in health-care settings. MMWR Recomm Rep. 2006;55(RR–14):1–17; quiz CE1-4.
   PubMedGoogle Scholar
• British HIV. Association, British association of sexual health and HIV, British infection society. UK national guidelines for HIV testing; 2008. [cited 2018 Sept 28]. Available at:  http://www.bhiva.org/documents/Guidelines/Testing/GlinesHIVTest08.pdf2008
   Google Scholar
• Office fédéral de la santé publique. Dépistage du VIH effectué sur l’initiative des médecins http://www.bag.admin.ch. Bulletin De l’OFSP. 2015;21:237–241.
   Google Scholar
• Darling KE, Gloor E, Ansermet-Pagot A, et al. Suboptimal access to primary healthcare among street-based sex workers in southwest Switzerland. Postgrad Med J. 2013;89:371-375 .
   PubMed Web of Science ®Google Scholar
• Lyons MS, Lindsell CJ, Haukoos JS, et al. Nomenclature and definitions for emergency department human immunodeficiency virus (HIV) testing: report from the 2007 conference of the national emergency department HIV testing consortium. Acad Emerg Med: Official Journal Soc Acad Emerg Med. 2009;16(2):168–177.
   PubMed Web of Science ®Google Scholar
• Joint United Nations Programme on HIV/AIDS. UNAIDS/WHO policy statement on HIV testing. Geneva, Switzerland; 2004. [cited 2018 Sept 28]. Available at: http://data.unaids.org/una-docs/hivtestingpolicy_en.pdf
   Google Scholar
• Gazzard B, Clumeck N, d’Arminio Monforte A, et al. Indicator disease-guided testing for HIV–the next step for Europe? HIV Med. 2008;9(Suppl 2):34–40.
   PubMed Web of Science ®Google Scholar
• Sullivan AK, Raben D, Reekie J, et al. Feasibility and effectiveness of indicator condition-guided testing for HIV: results from HIDES I (HIV indicator diseases across Europe study). PLoS One. 2013;8(1):e52845.
   PubMed Web of Science ®Google Scholar
• Sudarshi D, Pao D, Murphy G, et al. Missed opportunities for diagnosing primary HIV infection. Sex Transm Infect. 2008;84(1):14–16.
   PubMed Web of Science ®Google Scholar
• Ratcliffe L, Thomas S, Beeching NJ, et al. Acute presentations of HIV are still missed in low prevalence areas. Postgrad Med J. 2011;87(1025):170–174.
   PubMed Web of Science ®Google Scholar
• Levy I, Maor Y, Mahroum N, et al. Missed opportunities for earlier diagnosis of HIV in patients who presented with advanced HIV disease: a retrospective cohort study. BMJ Open. 2016;6(11):e012721.
   PubMed Web of Science ®Google Scholar
• Read P, Armstrong-James D, Tong CYW, et al. Missed opportunities for HIV testing—a costly oversight. QJM: Int J Med. 2011;104(5):421–424.
   PubMed Web of Science ®Google Scholar
• Lhopitallier L, Moulin E, Hugli O, et al. Missed opportunities for HIV testing among patients newly presenting for HIV care at a Swiss university hospital: a retrospective analysis. BMJ Open. 2018;8(6):e019806.
   PubMed Web of Science ®Google Scholar
• Mosimann V, Cavassini M, Hugli O, et al. HIV screening of patients with AIDS-defining cancers: a 10-year retrospective analysis of practices in a Swiss university hospital . HIV Med. 2014;15(10):631-634.
   PubMed Web of Science ®Google Scholar
• Cave J, Edwards S, Miller R, et al. Should we implement ‘opt-out’ HIV testing for patients with lymphoma? Clin Med. 2009;9(4):320–322.
   PubMed Web of Science ®Google Scholar
• Klein PW, Martin IBK, Quinlivan EB, et al. Missed opportunities for concurrent HIV-STD testing in an academic emergency department. Public Health Rep. 2014;129(Suppl 1):12–20.
   PubMedGoogle Scholar
• Merchant RC, Catanzaro BM. HIV testing in US EDs, 1993–2004. Am J Emerg Med. 2009;27(7):868–874.
   PubMed Web of Science ®Google Scholar
• Jenkins TC, Gardner EM, Thrun MW, et al. Risk-based human immunodeficiency virus (HIV) testing fails to detect the majority of HIV-infected persons in medical care settings. Sex Transm Dis. 2006;33(5):329–333.
   PubMed Web of Science ®Google Scholar
• Leblanc J, Hejblum G, Costagliola D, et al. Targeted HIV screening in eight emergency departments: the DICI-VIH cluster-randomized two-period crossover trial. Ann Emerg Med. 2018;72(1):41-53.
   Google Scholar
• Singh S, Song R, Johnson A, et al. HIv incidence, hiv prevalence, and undiagnosed hiv infections in men who have sex with men, united states. Ann Intern Med. 2018;168:685.
   PubMed Web of Science ®Google Scholar
• Haukoos JS, Lyons MS, Lindsell CJ, et al. Derivation and validation of the denver Human Immunodeficiency Virus (HIV) risk score for targeted HIV screening. Am J Epidemiol. 2012;175(8):838–846.
   PubMed Web of Science ®Google Scholar
• Elías MJP, Gómez-Ayerbe C, Elías PP, et al. Development and validation of an HIV risk exposure and indicator conditions questionnaire to support targeted HIV screening. Medicine. 2016;95(5):e2612.
   PubMed Web of Science ®Google Scholar
• Darling KE, de Allegri N, Fishman D, et al. Awareness of HIV testing guidelines is low among Swiss emergency doctors: a survey of five teaching hospitals in French-speaking Switzerland. PLoS One. 2013;8(9):e72812.
   PubMed Web of Science ®Google Scholar
• Spaulding AC, MacGowan RJ, Copeland B, et al. Costs of rapid HIV screening in an urban emergency department and a nearby county jail in the Southeastern United States. PLoS One. 2015;10(6):e0128408.
   PubMed Web of Science ®Google Scholar
• Hsu H, Walensky RP. Cost-effectiveness analysis and HIV screening: the emergency medicine perspective. Ann Emerg Med. 2011;58(1 Suppl 1):S145–S150.
   PubMed Web of Science ®Google Scholar
• Sanders GD, Bayoumi AM, Sundaram V, et al. Cost-effectiveness of screening for HIV in the era of highly active antiretroviral therapy. N Engl J Med. 2005;352(6):570–585.
   PubMed Web of Science ®Google Scholar
• Alvarez-Del Arco D, Monge S, Azcoaga A, et al. HIV testing and counselling for migrant populations living in high-income countries: a systematic review. Eur J Public Health. 2013;23(6):1039–1045.
   PubMed Web of Science ®Google Scholar
• Simpson WM, Johnstone FD, Goldberg DJ, et al. Antenatal HIV testing: assessment of a routine voluntary approach. BMJ. 1999;318(7199):1660–1661.
   PubMed Web of Science ®Google Scholar
• Jayaraman GC, Preiksaitis JK, Larke B. Mandatory reporting of HIV infection and opt-out prenatal screening for HIV infection: effect on testing rates. Can Med Assoc J. 2003;168(6):679–682.
   Web of Science ®Google Scholar
• Stanley B, Fraser J, Cox NH. Uptake of HIV screening in genitourinary medicine after change to “opt-out” consent. BMJ. 2003;326(7400):1174.
   PubMedGoogle Scholar
• Bell SA, Delpech V, Raben D, et al. HIV pre-test information, discussion or counselling? A review of guidance relevant to the WHO European Region. Int J STD AIDS. 2016;27(2):97–104.
   PubMed Web of Science ®Google Scholar
• Albrecht E, Frascarolo P, Meystre-Agustoni G, et al. An analysis of patients’ understanding of ‘routine’ preoperative blood tests and HIV screening. Is no news really good news? HIV Med. 2012;13(7):439–443.
   PubMed Web of Science ®Google Scholar
• Favre-Bulle T, Baudat D, Darling K, et al. Patients’ understanding of blood tests and attitudes to HIV screening in the emergency department of a Swiss teaching hospital: a cross-sectional observational study. Swiss Med Wkly. 2015;145:w14206.
   PubMed Web of Science ®Google Scholar
• De Rossi N, Dattner N, Cavassini M, et al. Patient and doctor perspectives on HIV screening in the emergency department: a prospective cross-sectional study. PLoS One. 2017;12(7):e0180389.
   PubMed Web of Science ®Google Scholar
• Haukoos JS, Hopkins E, Conroy AA, et al. Routine opt-out rapid HIV screening and detection of HIV infection in emergency department patients. Jama. 2010;304(3):284–292.
   PubMed Web of Science ®Google Scholar
• Lyons MS, Lindsell CJ, Ruffner AH, et al. Randomized comparison of universal and targeted HIV screening in the emergency department. J Acquir Immune Defic Syndr. 2013;64(3):315–323.
   PubMed Web of Science ®Google Scholar
• Haukoos JS, Hopkins E, Bender B, et al. Comparison of enhanced targeted rapid HIV screening using the Denver HIV risk score to nontargeted rapid HIV screening in the emergency department. Ann Emerg Med. 2013;61(3):353–361.
   PubMed Web of Science ®Google Scholar
• Medford-Davis LN, Yang K, Pasalar S, et al. Unintended adverse consequences of electronic health record introduction to a mature universal HIV screening program. AIDS Care. 2016;28(5):566–573.
   PubMed Web of Science ®Google Scholar
• Wilbur L, Huffman G, Lofton S, et al. The use of a computer reminder system in an emergency department universal HIV screening program. Ann Emerg Med. 2011;58(1 Suppl 1):S71–3 e1.
   PubMed Web of Science ®Google Scholar
• Schackman BR, Eggman AA, Leff JA, et al. Costs of expanded rapid HIV testing in four emergency departments. Public Health Rep. 2016;131(Suppl 1):71–81.
   PubMedGoogle Scholar
• d’Almeida KW, Kierzek G, de Truchis P, et al. Modest public health impact of nontargeted human immunodeficiency virus screening in 29 emergency departments. Arch Intern Med. 2012;172(1):12–20.
   PubMedGoogle Scholar
• Hempling MC, Zielicka-Hardy A, Ellis JP, et al. Routine HIV testing in the emergency department: feasible and acceptable? Int J STD AIDS. 2015;27(14):1267–1274.
   PubMed Web of Science ®Google Scholar
• White DAE, Scribner AN, Vahidnia F, et al. HIV screening in an urban emergency department: comparison of screening using an opt-in versus an opt-out approach. Ann Emerg Med. 2011;58(1, Supplement):S89–S95.
   PubMed Web of Science ®Google Scholar
• Isaac JK, Sanchez TH, Brown EH, et al. How compliance measures, behavior modification, and continuous quality improvement led to routine HIV screening in an emergency department in Brooklyn, New York. Public Health Rep. 2016;131(Suppl 1):63–70.
   PubMedGoogle Scholar
• Hoxhaj S, Davila JA, Modi P, et al. Using nonrapid HIV technology for routine, opt-out HIV screening in a high-volume urban emergency department. Ann Emerg Med. 2011;58(1 Suppl 1):S79–S84.
   PubMed Web of Science ®Google Scholar
• Haukoos JS, Hopkins E, Bender B, et al. Use of kiosks and patient understanding of opt‐out and opt‐in consent for routine rapid human immunodeficiency virus screening in the emergency department. Acad Emerg Med. 2012;19(3):287–293.
   PubMed Web of Science ®Google Scholar
• Geren KI, Lovecchio F, Knight J, et al. Identification of acute HIV infection using fourth-generation testing in an opt-out emergency department screening program. Ann Emerg Med. 2014;64(5):537–546.
   PubMed Web of Science ®Google Scholar
• Galbraith JW, Willig JH, Rodgers JB, et al. Evolution and escalation of an emergency department routine, opt-out HIV screening and linkage-to-care program. Public Health Rep. 2016;131(Suppl 1):96–106.
   PubMedGoogle Scholar
• Rayment M, Rae C, Ghooloo F, et al. Routine HIV testing in the emergency department: tough lessons in sustainability. HIV Med. 2013;14(Suppl 3):6–9.
   PubMedGoogle Scholar
• Sattin RW, Wilde JA, Freeman AE, et al. Rapid HIV testing in a southeastern emergency department serving a semiurban-semirural adolescent and adult population. Ann Emerg Med. 2011;58(1 Suppl 1):S60–S64.
   PubMed Web of Science ®Google Scholar
• Hsieh YH, Gauvey-Kern M, Peterson S, et al. An emergency department registration kiosk can increase HIV screening in high risk patients. J Telemed Telecare. 2014;20(8):454–459.
   PubMed Web of Science ®Google Scholar
• Gillet C, Darling KEA, Senn N, et al. Targeted versus non-targeted HIV testing offered via electronic questionnaire in a Swiss emergency department: A randomized controlled study. PLoS One. 2018;13(3):e0190767.
   PubMed Web of Science ®Google Scholar
• Jones R. The role of health kiosks in 2009: literature and informant review. Int J Environ Res Public Health. 2009;6(6):1818–1855.
   PubMed Web of Science ®Google Scholar
• Arbelaez C, Wright EA, Losina E, et al. Emergency provider attitudes and barriers to universal HIV testing in the emergency department. J Emerg Med. 2012;42(1):7–14.
   PubMed Web of Science ®Google Scholar
• Chen JC, Goetz MB, Feld JE, et al. A provider participatory implementation model for HIV testing in an ED. Am J Emerg Med. 2011;29(4):418–426.
   PubMed Web of Science ®Google Scholar
• Hecht CR, Smith MD, Radonich K, et al. A comparison of patient and staff attitudes about emergency department-based HIV testing in 2 urban hospitals. Ann Emerg Med. 2011;58(1 Suppl 1):S28–32 e1-4.
   PubMed Web of Science ®Google Scholar
• McGuire R, Moore E. Using a configurable EMR and decision support tools to promote process integration for routine HIV screening in the emergency department. J Am Med Inform Assoc. 2016;23(2):396–401.
   PubMed Web of Science ®Google Scholar
• Walensky RP, Reichmann WM, Arbelaez C, et al. Counselor- versus provider-based HIV screening in the emergency department: results from the universal screening for HIV infection in the emergency room (USHER) randomized controlled trial. Ann Emerg Med. 2011;58(1, Supplement):S126–S32.e4.
   PubMed Web of Science ®Google Scholar
• Centers for Disease Control and Prevention. Rapid HIV testing in emergency departments–three U.S. sites, January 2005-March 2006. MMWR. 2007;56(24):597–601.
   PubMedGoogle Scholar
• Lin J, Baghikar S, Mauntel‐Medici C, et al. Patient and system factors related to missed opportunities for screening in an electronic medical record–driven, opt‐out HIV screening program in the emergency department. Acad Emerg Med. 2017;24(11):1358–1368.
   PubMed Web of Science ®Google Scholar
• Kinsler JJ, Sayles JN, Cunningham WE, et al. Preference for physician vs. nurse-initiated opt-out screening on HIV test acceptance. AIDS Care. 2013;25(11):1442–1445.
   PubMed Web of Science ®Google Scholar
• Rayment M, Thornton A, Mandalia S, et al. HIV testing in non-traditional settings–the HINTS study: a multi-centre observational study of feasibility and acceptability. PLoS One. 2012;7(6):e39530.
   PubMed Web of Science ®Google Scholar
• Simpson WM, Johnstone FD, Boyd FM, et al. Uptake and acceptability of antenatal HIV testing: randomised controlled trial of different methods of offering the test. BMJ. 1998;316(7127):262–267.
   PubMedGoogle Scholar
• Meadows J, Jenkinson S, Catalan J, et al. Voluntary HIV testing in the antenatal clinic: differing uptake rates for individual counselling midwives. AIDS Care. 1990;2(3):229–233.
   PubMedGoogle Scholar
• Haukoos JS, Hopkins E, Bucossi MM. Routine opt-out HIV screening: more evidence in support of alternative approaches? Sex Transm Dis. 2014;41(6):403–406.
   PubMed Web of Science ®Google Scholar
• White DAE, Cheung PT, Scribner AN, et al. A comparison of HIV testing in the emergency department and urgent care. J Emerg Med. 2010;39(4):521–528.
   PubMed Web of Science ®Google Scholar
• Shahkolahi MM, Wilson A, Zucker L. Mobile-application-based HIV intervention: an opt-in approach to promote rapid HIV screening in an inner-city emergency department. Ann Emerg Med. 2013;62(4):S95.
   PubMed Web of Science ®Google Scholar
• Felsen UR, Cunningham CO, Zingman BS. Increased HIV testing among hospitalized patients who declined testing in the emergency department. AIDS Care. 2016;28(5):591–597.
   PubMed Web of Science ®Google Scholar
• Aronson ID, Cleland CM, Perlman DC, et al. Feasibility of a computer-based intervention addressing barriers to HIV testing among young patients who decline tests at triage. J Health Commun. 2016;21(9):1039–1045.
   PubMed Web of Science ®Google Scholar
• Henriquez‐Camacho C, Villafuerte‐Gutierrez P, Pérez‐Molina J, et al. Opt‐out screening strategy for HIV infection among patients attending emergency departments: systematic review and meta‐analysis. HIV Med. 2017;18(6):419–429.
   PubMed Web of Science ®Google Scholar
• White DA, Sadoun T, Tran T, et al. Increased acceptance rates of HIV screening using opt-out consent methods in an urban emergency department. J Acquir Immune Defic Syndr. 2011;58(3):277–282.
   PubMed Web of Science ®Google Scholar
• Montoy JC, Dow WH, Kaplan BC. Patient choice in opt-in, active choice, and opt-out HIV screening: randomized clinical trial. BMJ. 2016;532:h6895.
   PubMedGoogle Scholar
• Kelen GD, Hexter DA, Hansen KN, et al. Feasibility of an emergency department–based, risk-targeted voluntary HIV screening program. Ann Emerg Med. 1996;27(6):687–692.
   PubMed Web of Science ®Google Scholar
• Czarnogorski M, Brown J, Lee V, et al. The prevalence of undiagnosed HIV infection in those who decline HIV screening in an urban emergency department. AIDS Res Treat. 2011;2011:879065.
   PubMedGoogle Scholar
• Rakhmanina N, Messenger N, Phillips G 2nd, et al. Factors affecting acceptance of routine human immunodeficiency virus screening by adolescents in pediatric emergency departments. J Adolescent Health. 2014;54(2):176–182.
   PubMed Web of Science ®Google Scholar
• Lin J, Mauntel-Medici C, Heinert S, et al. Harnessing the power of the electronic medical record to facilitate an opt-out HIV screening program in an urban academic emergency department. J Public Health Manag Pract. 2017;23(3):264–268.
   PubMed Web of Science ®Google Scholar
• Brown J, Shesser R, Simon G, et al. Routine HIV screening in the emergency department using the new US centers for disease control and prevention guidelines: results from a high-prevalence area. J Acquir Immune Defic Syndr. 2007;46(4):395–401.
   PubMed Web of Science ®Google Scholar
• Signer D, Peterson S, Hsieh Y-H, et al. Scaling up HIV testing in an academic emergency department: an integrated testing model with rapid fourth-generation and point-of-care testing. Public Health Rep. 2016;131(1_suppl):82–89.
   PubMedGoogle Scholar
• Geren K, Moore E, Tomlinson C, et al. Detection of acute HIV infection in two evaluations of a new HIV diagnostic testing algorithm — United States, 2011–2013. MMWR. 2013;62(24):489–494.
   PubMed Web of Science ®Google Scholar
• White DAE, Giordano TP, Pasalar S, et al. Acute HIV Discovered During Routine HIV Screening With HIV Antigen-Antibody Combination Tests in 9 US Emergency Departments. Ann Emerg Med. 2018;72:29–40.e2.
   Web of Science ®Google Scholar