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Review

Nanotechnology-based promising strategies for the management of COVID-19: current development and constraints

ORCID Icon, , , , , , , & show all
Pages 1299-1308 | Received 26 Aug 2020, Accepted 12 Oct 2020, Published online: 08 Nov 2020

References

  • Itani R, Tobaiqy M, Al Faraj A. Optimizing use of theranostic nanoparticles as a life-saving strategy for treating COVID19 patients. Theranostics. 2020;10(13):5932–5942.
  • Sivansankarapillai VS, Pillai AM, Rahdar A, et al. On facing the SARS-CoV-2 (COVID-19) with combination of nanomaterials and medicine: possible strategies and first challenges. Nanomaterials. 2020;10(5):E852. DOI:10.3390/nano10050852.
  • Somvanshi S, Kharat PB, Saraf TS, et al. Multifunctional nano-magnetic particles assisted viral RNA-extraction protocol for potential detection of COVID-19. Mat Res Inn. 2020,DOI:10.1080/14328917.2020.1769350.
  • Uskokovic V. Why have nanotechnologies been underutilized in the global uprising against the coronavirus pandemic? Nanomedicine (Lond). 2020;15:1719–1734.
  • Rabiee N, Rabiee M, Bagherzadeh M, et al. COVID-19 and picotechnology: potential opportunities. Med Hypotheses. 2020a;144:109917.
  • Mousavizadeh L, Ghasemi S. Genotype and phenotype of COVID-19: their roles in pathogenesis. J Microbiol Immunol Infect. 2020. DOI:10.1016/j.jmii.2020.03.022
  • Rabiee N, Bagherzadeh M, Ghasemi A, et al. Point-of-use rapid detection of SARS-CoV-2: nanotechnology-enabled solutions for the covid-19 pandemic. Int J Mol Sci. 2020b;21:5126.
  • Shereen MA, Khan S, Kazmi A, et al. COVID-19 infection: origin, transmission, and characteristics of human coronaviruses. J Adv Res. 2020;24:91–98.
  • Micah AE, Su Y, Bachmeier SD, et al. Health sector spending and spending on HIV/AIDS, tuberculosis, and malaria, and development assistance for health: progress towards sustainable development goal 3. Lancet. 2020;396:693–724.
  • Sarkar S. Silver nanoparticles with bronchodilators through nebulisation to treat COVID 19 patients. J Curr Med Res Opin. 2020;3(4):449–450.
  • Alphandéry E. The potential of various nanotechnologies for coronavirus diagnosis/treatment highlighted through a literature analysis. Bioconjugate Chem. 2020;31:1873–1882.
  • Ahmadi S, Rabiee N, Bagherzadeh M, et al. Stimulus-responsive sequential release systems for drug and gene delivery. Nano Today. 2020;34:100914.
  • Rabiee N, Bagherzadeh M, Ghadiri AM, et al. Green synthesis of ZnO NPs via Salvia hispanica: evaluation of potential antioxidant, antibacterial, mammalian cell viability, H1N1 influenza virus inhibition and photocatalytic activities. J Biomed Nanotechol. 2020c;16(4):456–466.
  • Shen M, Zhou Y, Ye J, et al. Recent advances and perspectives of nucleic acid detection for coronavirus. J Pharm Anal. 2020;10:97–101.
  • Corman VM, Landt O, Kaiser M, et al. Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR. Eurosurveillance. 2020;25(3):2000045.
  • Chu DKW, Pan Y, Cheng SMS, et al. Molecular diagnosis of a novel coronavirus (2019-nCoV) causing an outbreak of pneumonia. Clin Chem. 2020;66:549–555.
  • Wang D, Hu B, Hu C, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus–infected pneumonia in Wuhan, China. JAMA. 2020;323:1061–1069.
  • Ardakani AA, Kanafi AR, Acharya UR, et al. Application of deep learning technique to manage COVID-19 in routine clinical practice using CT images: results of 10 convolutional neural networks. Comp Bio Med. 2020;121:103795.
  • Lei DP. The progression of computed tomographic (CT) images in patients with coronavirus disease (COVID-19) pneumonia. J Infect. 2020;80:e30–e31.
  • Ucar F, Korkmaz D. COVID diagnosis-net: deep bayes-squeeze net based diagnostic of the coronavirus disease 2019 (COVID-19) from X-ray images. Med Hypoth. 2020;140:109761. DOI:10.1016/j.mehy.2020.109761.
  • Panwar H, Gupta PK, Siddiqui MK, et al. Application of deep learning for fast detection of COVID-19 in X-rays using nCOVnet. Chaos, Solitons Fractal. 2020;138:109944.
  • Inchingolo R, Smargiassi A, Moro F, et al. The diagnosis of pneumonia in a pregnant woman with COVID-19 using maternal lung ultrasound. Am J Obstetrics Gynecol. 2020;223:9–11.
  • He R, Lu Z, Zhang L, et al. The clinical course and its correlated immune status in COVID-19 pneumonia. J Clin Virol. 2020;127:104361. DOI:10.1016/j.jcv.2020.104361.
  • Kermali M, Khalsa RK, Pillai K, et al. The role of biomarkers in diagnosis of COVID-19 – A systematic review. Life Sci. 2020;254:117788.
  • Vogel G. New blood tests for antibodies could show true scale of coronavirus pandemic. Science Mag. 2020. DOI:10.1126/science.abb8028
  • Demey B, Daher N, François C, et al. Dynamic profile for the detection of anti-SARS-CoV-2 antibodies using four immunochromatographic assays. J Infect. 2020;81:e6-e10.
  • Imai K, Tabata S, Ikeda M, et al. Clinical evaluation of an immunochromatographic IgM/IgG antibody assay and chest computed tomography for the diagnosis of COVID-19. J Cln Vir. 2020;128:104393.
  • Ivanov YD, Malsagova KA, Pleshakova TO, et al. Ultrasensitive detection of 2,4-dinitrophenol using nanowire biosensor. J Nanotech. 2018;2018:9549853. DOI:10.1155/2018/9549853.
  • Seo G, Lee G, Kim M, et al. Rapid detection of COVID-19 causative virus (SARS-CoV-2) in human nasopharyngeal swab specimens using field-effect transistor-based biosensor. ACS Nano. 2020;14(4):5135–5142.
  • Moitra P, Alafeef M, Dighe K, et al. Selective naked eye detection of SARS-CoV-2 mediated by N gene targeted antisense oligonucleotide capped plasmonic nanoparticles. ACS Nano. 2020;14:7617–7627.
  • Baker AN, Richards SJ, Guy CS, et al. The SARS-CoV-2 spike protein binds sialic acids and enables rapid detection in a lateral flow point of care diagnostic device. Chem Rxiv. 2020;DOI:10.1021/acscentsci.0c00855.
  • Ahmed SR, Kang SW, Oh S, et al. Chiral zirconium quantum dots: A new class of nanocrystals for optical detection of coronavirus. Heliyon. 2018;4:e00766.
  • Chattopadhyay S, Chen JY, Hu CMJ, et al. Nanoparticle vaccines adopting virus-like features for enhanced immune potentiation. Nanotheranostics. 2017;1:244–260.
  • Arnon R, Ben-Yedidia T. Old and new vaccine approaches. Int Immunopharmacol. 2003;3:1195–1204.
  • Kim M, Park J, Shon Y, et al. Nanotechnology and vaccine development: A review. Asian J Pharm Sci. 2014;9(5):227–235.
  • Lazarou J, Pomeranz BH, Corey PN. Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. JAMA. 1998;279:1200–1205.
  • Mamo T, Poland GA. Nanovaccinology: the next generation of vaccines meets 21st century materials science and engineering. Vaccine. 2012;30:6609–6611.
  • Zaman M, Good MF, Toth I. Nanovaccines and their mode of action. Methods. 2013;60(3):226–231.
  • Zhao L, Seth A, Wibowo N, et al. Nanoparticle vaccines. Vaccine. 2014;32:327–337.
  • Lugade AA, Bharali DJ, Pradhan V, et al. Single low-dose un-adjuvanted HBsAg nanoparticle vaccine elicits robust, durable immunity. Nanomed Nanotechnol Biol Med. 2013;9(7):923–934.
  • Salvador A, Sandgren KJ, Liang F, et al. Design and evaluation of surface and adjuvant modified PLGA microspheres for uptake by dendritic cells to improve vaccine responses. Int J Pharm. 2015;496(2):371–381.
  • Eidi H, Joubert O, Attik G, et al. Cytotoxicity assessment of heparin nanoparticles in NR8383 macrophages. Int J Pharm. 2010;396(1–2):156–165.
  • Diaz-Arévalo D, Zeng M. Nanoparticle-based vaccines opportunities and limitations. In: Shegokar R, editor. Nanopharmaceuticals. UK: Eslevier; 2020. p. 135–150.
  • Smith DM, Simon JK, Baker JR. Applications of nanotechnology for immunology. Nature Rev Immunol. 2013;13:592–605.
  • Foged C, Brodin B, Frokjaer S, et al. Article size and surface charge affect particle uptake by human dendritic cells in an in vitro model. Int J Pharm. 2005;298:315–322.
  • Vallhov H, Qin J, Johansson SM, et al. The importance of an endotoxin-free environment during the production of nanoparticles used in medical applications. Nano Lett. 2006;6:1682–1686.
  • Mottram PL, Leong D, Crimeen-Irwin B, et al. Type 1 and 2 immunity following vaccination is influenced by nanoparticle size: formulation of a model vaccine for respiratory syncytial virus. Mol Pharm. 2007;4:73–84.
  • Wang X, Ishida T, Kiwada H. Anti-PEG IgM elicited by injection of liposomes is involved in the enhanced blood clearance of a subsequent dose of PEGylated liposomes. J Control Release. 2007;119:236–244.
  • Ishida T, Wang X, Shimizu T, et al. PEGylated liposomes elicit an anti-PEG IgM response in a T cell-independent manner. J Control Release. 2007;122:349–355.
  • Kheirollahpour M, Mehrabi M, Dounighi N, et al. Nanoparticles and vaccine development. Pharm Nanotech. 2020;8:6–21.
  • Hajizade A, Ebrahimi F, Salmanian A, et al. Nanoparticles in vaccine development. J App Biotech Report. 2014;1(4):125–134.
  • Poon C, Patel A. Organic and inorganic nanoparticle vaccines for prevention of infectious diseases. Nano Express. 2020;1:012001.
  • Nikaeen G, Abbaszadeh S, Yousefinejad S. Application of nanomaterials in treatment, anti-infection and detection of coronaviruses. Future Med. 2020;15:1743–5889.
  • Tong Y, Ruiqi RM, Leung D, et al. Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. N Engl J Med. 2020;382(13):1199–1207.
  • Chen Y, Liu Q, Guo D. Emerging coronaviruses: genome structure, replication, and pathogenesis. J Med Virol. 2020;92(4):418–423.
  • Kampf G, Todt D, Pfaender S, et al. Persistence of coronaviruses on inanimate surfaces and its inactivation with biocidal agents. J Hosp Infect. 2020;104(3):246–251.
  • Sportelli MC, Longano D, Bonerba E, et al. Electrochemical preparation of synergistic nanoantimicrobials. Molecules. 2020;25:49.
  • Tavakoli A, Ataei-Pirkooh A, Mm Sadeghi G, et al. Polyethylene glycol-coated zinc oxide nanoparticle: an efficient nano weapon to fight against herpes simplex virus type 1. Nanomedicine (Lond). 2018;13(21):2675–2690.
  • Hang X, Peng H, Song H, et al. Antiviral activity of cuprous oxide nanoparticles against hepatitis C virus in vitro. J Virol Methods. 2015;222:150–157.
  • Fujimori Y, Sato T, Hayata T, et al. Novel antiviral characteristics of nanosized copper(I) iodide particles showing inactivation activity against 2009 pandemic H1N1 influenza virus. Appl Environ Microbiol. 2011;78(4):951–955.
  • Lysenko V, Lozovski V, Lokshyn M, et al. Nanoparticles as antiviral agents against adenoviruses. Adv Nat Sci: Nanosci Nanotechnol. 2018;9:025021.
  • Torkelson A, da Silva AK, Love DC, et al. Investigation of quaternary ammonium silane-coated sand filter for the removal of bacteria and viruses from drinking water. J Appl Microbiol. 2012;113:1196–1207.
  • Bhattacharjee S, Joshi R, Chughtai AA. Graphene modified multifunctional personal protective clothing. Adv Mater Interfaces. 2019;6:1900622.
  • Balagna C, Perero S, Percivalle E, et al. Virucidal effect against coronavirus SARS-CoV-2 of a silver nanocluster/silica composite sputtered coating. Open Ceramics. 2020;1:100006.
  • Rai M, Deshmukh SD, Ingle AP, et al. Metal nanoparticles: the protective nanoshield against virus infection. Crit Rev Microbiol. 2016;42:46–56.
  • Dicastillo CL, Vidal CP, Falcó I, et al. antimicrobial bilayer nanocomposites based on the incorporation of as-synthetized hollow zinc oxide nanotubes. Nanomaterials (Basel). 2020;10(3):503.
  • Gaikwad S, Ingle A, Gade A, et al. Antiviral activity of mycosynthesized silver nanoparticles against herpes simplex virus and human parainfluenza virus type 3. Int J Nanomed. 2013;8:4303–4314.
  • Rai M, Birla S, Ingle AP, et al. Nanosilver: an inorganic nanoparticle with myriad potential applications. Nanotechnol Rev. 2014;3(3):281–309.
  • Rai MK, Yadav A, Gade A. Silver nanoparticles as a new generation of antimicrobials. Biotech Adv. 2009;27:76–83.
  • Chen YN, Hsueh YH, Hsieh CT, et al. Antiviral activity of graphene–silver nanocomposites against non-enveloped and enveloped viruses. Int J Environ Res Public Health. 2016;13:430.
  • Kumar S, Khilnani A, Sharma SK. Predictors of requirement of mechanical ventilation in patients with chronic obstructive pulmonary disease with acute respiratory failure. Lung India. 2013;30(3):172–182.
  • Nho R. Pathological effects of nano-sized particles on the respiratory system. Nanomed Nanotech Bio Med. 2020;29:102242.
  • Kasper M, Barth K. Potential contribution of alveolar epithelial type I cells to pulmonary fibrosis. Biosci Rep. 2017;37(6):BSR20171301.
  • Song KS, Sung JH, Ji JH, et al. Recovery from silver-nanoparticle-exposure-induced lung inflammation and lung function changes in Sprague Dawley rats. Nanotoxicology. 2013;7:169–180.
  • Sung JH, Ji JH, Park JD, et al. Subchronic inhalation toxicity of silver nanoparticles. Toxicol Sci. 2009;108(2):452–461.
  • Hadrup N, Sharma AK, Loeschner K, et al. Pulmonary toxicity of silver vapours, nanoparticles and fine dusts: A review. Regulatory Toxicol Pharmacol. 2020;115:104690.
  • Buzea C, Pacheco I. Toxicity of nanoparticles. Nanotech Eco-Efficient Const. 2019;705–754. DOI:10.1016/b978-0-08-102641-0.00028
  • Zhu M, Nie G, Meng H, et al. Physicochemical properties determine nanomaterial cellular uptake, transport, and fate. Acc Chem Res. 2013;46(3):622–631.
  • Yu LE, Yung LYL, Ong CN, et al. Translocation of gold nanoparticles after inhalation exposure in rats was observed. Nanotoxicology. 2007;1:235–242.
  • Gupta I, Duran N, Rai M. Nano-silver toxicity: emerging concerns and consequences in human health. In: Rai M, Cioffi N, editors. Nano-antimicrobials: progress and Prospects. Verlag Germany: Springer; 2012. p. 525–548.
  • Longmire M, Choyke PL, Kobayashi H. Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats. Nanomedicine (Lond). 2008;3(5):703–717.
  • Osman N, Sexton D, Saleem I. Toxicological assessment of nanoparticle interactions with the pulmonary system. Nanotoxicology. 2020;14(1):21–58.

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