Cyclic AMP-dependent signaling system is a primary metabolic target for non-thermal effect of microwaves on heart muscle hydration

References

• Abdelsamie, M. A., Rahman, R. A., Mustafa, S., et al. (2014). Evaluation of electric and magnetic fields distribution and SAR induced in 3D models of water containers by radiofrequency radiation using FDTD and FEM simulation techniques. J. Electromagn. Anal. Appl. 6:213–232.
   Google Scholar
• Adey, W. R. (1981). Tissue interactions with non-ionizing electromagnetic field. Physiol. Rev. 61:435–514.
   PubMed Web of Science ®Google Scholar
• Ayrapetyan, G., Dadasyan, E., Mikayelyan, E., et al. (2009). Cell bathing medium as a target for non-thermal effect of MMW on heart muscle contractility. PIERS Proc. Electromagn. Acad. Moscow, Russia 10:1057–1060.
   Google Scholar
• Ayrapetyan, S. N., Stamboltsyan, Kh. V., Sulemanyan, M. A. (1984a). On the discrete character of change of helix snail neuron volume in solutions of different tonicity. Dokl.Akad.Nauk SSSR 278:1238–1240.
   Google Scholar
• Ayrapetyan, S. N., Suleymanyan, M. A., Sagian, A. A., et al. (1984b). Autoregulation of electrogenic sodium pump. Cel. Mol. Neurobiol. 4:367–384.
   PubMed Web of Science ®Google Scholar
• Ayrapetyan, S. N., Rychkov, G. Y. (1985). The presence of reserve ion channels in membranes of giant snail neurons and giant squid axons. DAN SSSR 285:1464–1467(in Russian).
   PubMedGoogle Scholar
• Ayrapetyan, S. N., Rychkov, G. Y., Suleymanian, M. A. (1988a). Modulation of calcium currents in the snail neuron membrane by osmotic gradient. Dokl. Akad. Nauk SSSR 300:983–985 (in Russian).
   PubMedGoogle Scholar
• Ayrapetyan, S. N., Arvanov, V. L., Maginyan, S. B. (1988b). The pharmacological characteristics of two types of cholinoreceptors in the membrane dialyzed neurons. Comput. Biochem. Physiol. 90C:29–39.
   Google Scholar
• Ayrapetyan, S. N., Dadasyan, E., Ayrapetyan, G., et al. (2009). The non-thermal effect of weak intensity millimeter waves on physicochemical properties of water solutions. Electromagn. Biol. Med. 28:331–341.
   PubMed Web of Science ®Google Scholar
• Ayrapetyan, S., De, J. (2014). Cell hydration as a biomarker for estimation of biological effects of non-ionizing radiation on cells and organisms. Sci. World J., Article ID 890518, Doi:10.1155/2014/890518.
   Google Scholar
• Ayrapetyan, S. N. (2015). The role of cell hydration in realization of biological effects of non-ionizing radiation (NIR). Electromagn. Biol. Med. 34:197–210.
   PubMed Web of Science ®Google Scholar
• Ayrapetyan, S. N., Avanesian, A. S., Avetisian, T. H., et al. (1994). Physiological effects of magnetic fields may be mediated through actions on the state of calcium ions in solution. In: Carpenter, D., Ayrapetyan, S., (eds.). Biological Effects of Electric and Magnetic Fields: Volume 1, Cambridge, MA: Academic Press. pp. 181–192.
   Google Scholar
• Ayrapetyan, S. N. (2006). Cell aqua medium as a preliminary target for the effect of electromagnetic fields. In: Ayrapetyan, S., Markov, M., (eds.) Bioelectromagnetics: Current Concepts, NATO Security through Science Series. The Netherlands: Springer Press. pp. 31–64.
   Google Scholar
• Baker, P. F., Blaustein, M. P., Hodgkin, A. L., et al. (1969). The influence of calcium on sodium efflux in squid axons. J. Physiol. 200:431–458.
   PubMed Web of Science ®Google Scholar
• Bioinitiative Report. (2012). A radionale for biologielly-based exposure standards for low-intensity electromagnetic radiation. WHO: Working Group, Sage C., Carpenter D.O., (Eds). Retrieved from: www.bioinitiative.org
   Google Scholar
• Blaustein, M. P., Lederer, W. J. (1999). Na+/Ca2+ exchange. Its physiological implications. Physiol. Rev. 79:763–854.
   PubMed Web of Science ®Google Scholar
• Chaplin, M. F. (2006). Information exchange within extracellular water. In: Pollack, G., et al. eds. Water and the Cell. Netherlands: Springer. pp. 113–123.
   Google Scholar
• Deghoyan, A., Heqimyan, A., Nikoghosyan, A., et al. (2012). Cell bathing medium as a target for non thermal effect of millimeter waves. Electromagn. Biol. Med. 31:132–142.
   PubMed Web of Science ®Google Scholar
• Deghoyan, A., Simonyan, R., Wachtel, H., et al. (2013). The skeletal muscle impedancemetric characteristics as a marker for detection of functional state of organism. ISRN Biophys. 2013: Article ID 948074.
   Google Scholar
• Devyatkov, N. D. (1973). Effect of a SHF (mm-band) radiation on biological objects. UspekhiFizicheskikhNauk 110:453–454(in Russian)
   Google Scholar
• Devyatkov, N. D., Golant, M. B., Betsky, O. V. (1991). Millimeter Waves and their Role in the Processes of Life. Moscow, Russia: Radio i Svyaz. (in Russian)
   Google Scholar
• Haussinger, D. (1996). The role of cellular hydration in regulation of cell function. Biochem. J. 313:697–710.
   PubMed Web of Science ®Google Scholar
• Heqimyan, A., Deghoyan, A., Ayrapetyan, S. (2011). Ketamine–induced cell dehydration as a mechanism of its analgesic and anesthetic effects. J. Int. Dent. Med. Res. 4:42–49.
   Google Scholar
• Hoffman, E. K., Sorensen, B. H., Sauter, D. P., et al. (2015). Role of volume-regulated and Calcium-activated anion channels in Cell volume homeostasis, Cancer and Drug resistance. CHANNELS (AUSTIN,TEX.) 9:380–396.
   PubMed Web of Science ®Google Scholar
• Huang, H., Lu, F. I., Jia, S., et al. (2007). Amotl2 is essential for cell movements in zebrafish embryo and regulates c-Src Translocation. Development 134:979–988.
   PubMed Web of Science ®Google Scholar
• Klassen, V. I. (1982). Magnetized Water Systems. Moscow, Russia: Chemistry Press. pp. 296 (In Russian)
   Google Scholar
• Kojima, M., Ayrapetyan, S., Koketsu, K. (1984). On the membrane potential independent mechanism of sodium pump-induced inhibition of spontaneous electrical activity of Japanese land snail neurons. Comput. Biochem. Physiol. 77(A):577–583.
   Web of Science ®Google Scholar
• Krnjevic, K. (1992). Cellular and synaptic actions of general anaesthetics. GenPharmacol. 23:965–975.
   Google Scholar
• Lednev, V.V. (1991). Possible mechanism for the influence of weak magnetic field interactions with biological systems. Bioelectromagnetics 18:455–446
   Google Scholar
• Markov, M. (2015). Benefit and hazard of electromagnetic fields. In: Prof. Marko S. Markov (eds). Electromagnetic Fields in Biology and Medicine. Boca Raton, FL: CRC Press. 3, pp. 15–28.
   Google Scholar
• Nakano, S., Muramatsu, T., Nishimura, S., et al. (2012). Cardiomyocyte and Heart Failure. In: Biochemistry, Genetics and Molecular Biology. http://dx.doi.org/10.5772/47772
   Google Scholar
• Narinyan, L., Ayrapetyan, S. (2015). Dysfunction of nMOuabain-induced activation of the signaling system responsible for age-related heart muscle failure. Adv. Life Sci. 5:73–84.
   Google Scholar
• Narinyan, L., Ayrapetyan, G., Ayrapetyan, S. (2012). Age-dependent magnetosensitivity of heart muscle hydration. Bioelectromagnetics 33:452–458.
   PubMed Web of Science ®Google Scholar
• Narinyan, L., Ayrapetyan, G., Ayrapetyan, S. (2013). Age-dependent magnetosensitivity of heart muscle ouabain receptors. Bioelectromagnetics 34:312–322
   PubMed Web of Science ®Google Scholar
• Narinyan, L., De, J., Ayrapetyan, S. (2014). Age-dependent increase in Ca 2+ exchange magnetosensitivity in rat heart muscles. Biochem. Biophys. (BAB) 2:39–49.
   Google Scholar
• Pakorny, J., Pakorny, J., Foletti, A., et al. (2015). Mitochondrial dysfunction and disturbed coherence: Gate to Cancer. Pharmaceuticals 8:675–695.
   Google Scholar
• Panin, L. E., Tretiakova, T. A. (1981). Effect of cAMP of glycolysis and glycogenolysis in the liver and adrenals of white rats. Biull. Eksp. Biol. Med. 92:37–39.
   PubMedGoogle Scholar
• Parsegian, V. A., Rand, R. P., Rau, D. C. (2000). Osmotic stress, crowding, preferential hydration and binding: A comparison of perspectives. USA: Proc. Nat. Sci. 97:3987–3992. Pharmaceuticals DOI:10.3390/ph8040675.
   Google Scholar
• Saghian, A. A., Ayrapetyan, S. N., Carpenter, D. O. (1996). Low dose of ouabain stimulates the Na/Ca exchange in neurons. Cell. Mol. Neurobiol., 16:489–498.
   PubMed Web of Science ®Google Scholar
• Shishkin, G., Ageev, I., Rybin, Y., et al. (2013). Research of water response under the action of the infrared human body radiation by water conductometric sensors open. J. Appl. Sci. 3:278–284.
   Web of Science ®Google Scholar
• Simonyan, R., Ghulyan, A., Ayrapetyan, S. (2006). High-frequency device for the measurement of specific absorption rate of biotissues of high intensity. In: Ayrapetyan, S., Markov, M., (eds.) Bioelectromagnetics: Current Concepts. NATO Science Series, The Netherlands: Springer Press. pp. 291–296.
   Google Scholar
• Takahashi, R., Aprison, M. (1964). Acetylcholine content of discrete areas of the brain obtained by a near-freezing method. J. Neurochem., 11:887–898.
   PubMed Web of Science ®Google Scholar
• Xie, Z., Askari, A. (2002). Na+/K+-АТPase as a signal transducer. Eur. J. Biochem., 269:2434–2439.
   PubMedGoogle Scholar
• Ziskin, M. C. (2006). Physiological mechanisms underlying millimeter wave therapy. In: Ayrapetyan, S., Markov, M. (eds). Bioelectromagnetics Current Concepts. Netherlands: Springer. pp. 241–251.
   Google Scholar