Induction of Alcohol-Metabolizing Enzymes and Heat Shock Protein Expression by Ethanol and Modulation by Fenugreek Seed Polyphenols in Chang Liver Cells

REFERENCES

• H. M. Beere, B. B. Wolf, K. Cain, D. D. Mosser, A. Mahboubi, T. Kuwana, P. Tailor, R. I. Morimoto, G. M. Cohen, and D. R. Green. (2000). Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome. Nature Cell Biol. 2:469–475.
   PubMed Web of Science ®Google Scholar
• S. B. Berman, and T. G. Hastings. (1999). Dopamine oxidation alters mitochondrial respiration and induces permeability transition in brain mitochondria: implications for Parkinson's disease. J. Neurochem. 73:1127–1137.
   PubMed Web of Science ®Google Scholar
• J. Cai, J. Yang, and D. P. Jones. (1998). Mitochondrial control of apoptosis: the role of cytochrome c. Biochim. Biophys. Acta 1366:139–149.
   PubMed Web of Science ®Google Scholar
• V. Calabrese, G. Testa, A. Ravagna, T. E. Bates, and A. M. Stella. (2000). HSP70 induction in the brain following ethanol administration in the rat: regulation by glutathione redox state. Biochem. Biophys. Res. Commun. 269:397–400.
   PubMed Web of Science ®Google Scholar
• D. L. Carbone, J. A. Doorn, Z. Kiebler, B. R. Ickes, and D. R. Petersen. (2005). Modification of heat shock protein 90 by 4-hydroxynonenal in a rat model of chronic alcoholic liver disease. J. Pharmacol. Exp. Ther. 315:8–15.
   PubMed Web of Science ®Google Scholar
• A. I. Cederbaum. (2001). Alcohol, oxidative stress and cell injury—a serial review. Free Radic. Biol. Med. 31:1524–1526.
   PubMed Web of Science ®Google Scholar
• Y. C. Chen, S. C. Shen, and H. Y. Lin. (2003). Rutinoside at C7 attenuates the apoptosis inducing activity of flavonoids. Biochem. Pharmacol. 66:1139–1150.
   PubMed Web of Science ®Google Scholar
• H. L. Chiang, S. R. Terlecky, C. P. Plant, and J. F. Dice. (1989). A role for a 70-kilodalton heat shock protein in lysosomal degradation of intracellular proteins. Science 246:382–385.
   PubMed Web of Science ®Google Scholar
• Y. Deng, Y. Lin, and X. Wu. (2002). TRAIL-induced apoptosis requires Baxdependent mitochondrial release of Smac/DIABLO. Genes Dev. 16:33–45.
   PubMed Web of Science ®Google Scholar
• J. Dessolin, M. Schuler, A. Quinart, Giorgi F. De, L. Ghosez, and F. Ichas. (2002). Selective targeting of synthetic antioxidants to mitochondria: towards a mitochondrial medicine for neurodegenerative diseases?. Eur. J. Pharmacol. 447:155–161.
   PubMed Web of Science ®Google Scholar
• P. Dixit, S. Ghaskadbi, H. Mohan, and T. P. Devasagayam. (2005). Antioxidant properties of germinated fenugreek seeds. Phytother. Res. 19:977–983.
   PubMed Web of Science ®Google Scholar
• R. Edenharder, J. W. Sager, H. Glatt, E. Muckel, and K. L. Platt. (2002). Protection by beverages, fruits, vegetables, herbs, and flavonoids against genotoxicity of 2-acetylaminofluorene and 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (PhIP) in metabolically competent V79 cells. Mutat. Res. 521:57–72.
   PubMed Web of Science ®Google Scholar
• G. Elia, and M. G. Santoro. (1994). Regulation of heat shock protein synthesis by quercetin in human erythroleukemia cells. Biochem. J. 300:201–209.
   PubMed Web of Science ®Google Scholar
• G. Elia, C. Amici, A. Rossi, and M. G. Santoro. (1996). Modulation of prostaglandin A1-induced thermotolerance by quercetin in human leukemic cells: Role of heat shock protein 70. Cancer Res. 56:210–217.
   PubMed Web of Science ®Google Scholar
• J. Fehér, G. Deák, G. Müzes, I. Láng, V. Niederland, K. Nékám, and M. Kárteszi. (1989). Liver-protective action of silymarin therapy in chronic alcoholic liver diseases. Orvosi Hetilap 130:2723–2727.
   PubMedGoogle Scholar
• M. J. Gething, and J. Sambrook. (1992). Protein folding in the cell. Nature 355:33–45.
   PubMed Web of Science ®Google Scholar
• S. B. Goldfarb, O. B. Kashlan, J. N. Watkins, L. Suaud, W. Yan, T. R. Kleyman, and R. C. Rubenstein. (2006). Differential effects of Hsc70 and Hsp70 on the intracellular trafficking and functional expression of epithelial sodium channels. Proc. Natl. Acad. Sci. USA 15:5817–5822.
   Google Scholar
• N HailJr.. (2005). Mitochondria: a novel target for the chemoprevention of cancer. Apoptosis 10:687–705.
   PubMed Web of Science ®Google Scholar
• N. Hosokawa, K. Hirayoshi, A. Nakai, Y. Hosokawa, N. Marui, M. Yoshida, T. Sakai, H. Nishino, A. Aoike, K. Kawai, and K. Nagata. (1990). Flavonoids inhibit the expression of heat shock proteins. Cell Struct. Funct. 15:393–401.
   PubMed Web of Science ®Google Scholar
• Y. Ishikawa, and M. Kitamura. (2000). Anti-apoptotic effect of quercetin: intervention in the JNK- and ERK-mediated apoptotic pathways. Kidney Int. 58:1078–1087.
   PubMed Web of Science ®Google Scholar
• S. Kaviarasan, and C. V. Anuradha. (2007). Fenugreek (Trigonella foenum graecum) seed polyphenols protect liver from alcohol toxicity: a role on hepatic detoxification system and apoptosis. Die Pharmazie 62:299–304.
   PubMed Web of Science ®Google Scholar
• S. Kaviarasan, G. H. Naik, R. Gangabhagirathi, C. V. Anuradha, and K. I. Priyadarsini. (2007). In vitro studies on antiradical and antioxidant activities of fenugreek (Trigonella foenum graecum) seeds. Food Chem. 103:31–37.
   Web of Science ®Google Scholar
• S. Kaviarasan, P. Ramamurty, N. Gunasekaran, E. Varalakshmi, and C. V. Anuradha. (2006). Fenugreek seed extract prevents ethanol-induced toxicity and apoptosis in Chang liver cells. Alcohol Alcoholism 41:267–273.
   PubMed Web of Science ®Google Scholar
• W. M. Keung. (1993). Biochemical studies of a new class of alcohol dehydrogenase inhibitors from Radix puerariae. Alcohol Clin. Exp. Res. 17:1254–1260.
   PubMed Web of Science ®Google Scholar
• P. Khosla, D. D. Gupta, and R. K. Nagpal. (1995, April). Effect of Trigonella foenum graecum (Fenugreek) on blood glucose in normal and diabetic rats. Indian J. Pharmacol. 39(2):173–174.
   Google Scholar
• C. H. Ko, S. C. Shen, and Y. C. Chen. (2004). Hydroxylation at C40 or C6 is essential for apoptosis-inducing activity of flavanone through activation of the caspase-3 cascade and production of reactive oxygen species. Free Radic. Biol. Med. 36:897–910.
   PubMed Web of Science ®Google Scholar
• B. T. Lai, N. W. Chin, A. E. Stanek, W. Keh, and K. W. Lanks. (1984). Quantitation and intracellular localization of the 85 K heat shock protein by using monoclonal and polyclonal antibodies. Mol. Cell Biol. 4:2802–2810.
   PubMed Web of Science ®Google Scholar
• E. B. Lasunskaia, I. I. Fridlianskaia, Z. A. Darieva, M. S. da Silva, M. M. Kanashiro, and B. A. Margulis. (2003). Transfection of NS0 myeloma fusion partner cells with HSP70 gene results in higher hybridoma yield by improving cellular resistance to apoptosis. Biotechnol. Bioeng. 81:496–504.
   PubMed Web of Science ®Google Scholar
• S. Lautraite, A. C. Musonda, J. Doehmer, G. O. Edwards, and J. K. Chipman. (2002). Flavonoids inhibit genetic toxicity producedby carcinogens in cells expressing CYP1A2 and CYP1A1. Mutagenesis 17:45–53.
   PubMed Web of Science ®Google Scholar
• L. Y. Li, X. Luo, and X. Wang. (2001). Endonuclease G is an apoptotic DNase when released from mitochondria. Nature 412:95–99.
   PubMed Web of Science ®Google Scholar
• H. Y. Lin, S. H. Juan, S. C. Shen, F. L. Hsu, and Y. C. Chen. (2003). Inhibition of lipopolysaccharide-induced nitric oxide production by flavonoids in RAW264.7 macrophages involves heme oxygenase-1. Biochem. Pharmacol. 66:1821–1832.
   PubMed Web of Science ®Google Scholar
• X. Liu, C. N. Kim, J. Yang, R. Jemmerson, and X. Wang. (1996). Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 86:147–157.
   PubMed Web of Science ®Google Scholar
• O. H. Lowry, A. L. Rosebrough, N. J. Farr, and R. J. Randall. (1951). Protein measurment with folin phenol reagent. J. Biol. Chem. 193:265–275.
   PubMed Web of Science ®Google Scholar
• M. F. Miles, J. E. Diaz, and V. S. DeGuzman. (1991). Mechanisms of neuronal adaptation to ethanol. Ethanol induces Hsc70 gene transcription in NG108–15 neuroblastoma x glioma cells. J. Biol. Chem. 266:2409–2414.
   PubMed Web of Science ®Google Scholar
• M. Noroozi, W. J. Angerson, and M. E. Lean. (1998). Effects of flavonoids and Vitamin C on oxidative DNA damage to human lymphocytes. Am. J. Clin. Nutr. 67:1210–1218.
   PubMed Web of Science ®Google Scholar
• L. Oliver, M. T. LeCabellec, G. Pradal, K. Meflah, G. Kroemer, and F. M. Vallette. (2005). Constitutive presence of cytochrome c in the cytosol of a chemoresistant leukemic cell line. Apoptosis 10:277–287.
   PubMed Web of Science ®Google Scholar
• C. Park, H. S. So, C. H. Shin, S. H. Baek, B. S. Moon, S. H. Shin, H. S. Lee, D. W. Lee, and R. Park. (2003). Quercetin protects the hydrogen peroxide-induced apoptosis via inhibition of mitochondrial dysfunction in H9c2 cardiomyoblast cells. Biochem. Pharmacol. 66:1287–1295.
   PubMed Web of Science ®Google Scholar
• A. Saleh, S. M. Srinivasula, L. Balkir, P. D. Robbins, and E. S. Alnemri. (2000). Negative regulation of the Apaf-1 apoptosome by Hsp70. Nat. Cell Biol. 2:476–483.
   PubMed Web of Science ®Google Scholar
• M. Shang, S. Cai, J. Han, J. Li, Y. Zhao, J. Zheng, T. Namba, S. Kadota, Y. Tezuka, and W. Fan. (1998a). Studies on flavonoids from fenugreek (Trigonella foenum graecum L). Zhongguo Zhong Yao Za Zhi 23:614–616.
   PubMedGoogle Scholar
• M. Shang, S. Cai, and X. Wang. (1998b). Analysis of amino acids in Trigonella foenum graecum seeds. Zhong Yao Cai 21:188–190.
   PubMedGoogle Scholar
• S. C. Shen, C. H. Ko, S. W. Tseng, S. H. Tsai, and Y. C. Chen. (2004). Structurally related antitumor effects of flavanones in vitro and in vivo: involvement of caspase 3 activation, p21 gene expression, and reactive oxygen species production. Toxicol. Appl. Pharmacol. 197:84–95.
   PubMed Web of Science ®Google Scholar
• S. L. Singleton, and J. A. Rossi. (1965). Colorimetry of total phenolics with phosphomolybdic—phosphotungstic acid reagents. Am. J. Enol. Vitic 16:144–158.
   Google Scholar
• S. A. Susin, H. K. Lorenzo, N. Zamzami, I. Marzo, B. E. Snow, G. M. Brothers, J. Mangion, E. Jacotot, P. Costantini, M. Loeffler, N. Larochette, D. R. Goodlett, R. Aebersold, D. P. Siderovski, J. M. Penninger, and G. Kroemer. (1999). Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 397:441–446.
   PubMed Web of Science ®Google Scholar
• V. Thirunavukkarasu, C. V. Anuradha, and P. Viswanathan. (2003). Protective effect of Fenugreek (Trigonella foenum graecum) seeds in experimental ethanol toxicity. Phytother. Res. 17:737–743.
   PubMed Web of Science ®Google Scholar
• W. Voos, B. D. Gambill, B. Guiard, N. Pfanner, and E. A. Craig. (1993). Presequence and mature part of preproteins strongly influence the dependence of mitochondrial protein import on heat shock protein 70 in the matrix. J. Cell Biol. 123:119–126.
   PubMed Web of Science ®Google Scholar
• H. Wegele, L. Muller, and J. Buchner. (2004). Hsp70 and Hsp90-a relay team for protein refolding. Rev. Physiol. Biochem. Pharmacol. 151:1–44.
   PubMed Web of Science ®Google Scholar
• D. Wu, and A. I. Cederbaum. (2002). Cyclosporine A protects against arachidonic acid toxicity in rat hepatocytes: role of CYP2E1 and mitochondria. Hepatology 35:1420–1430.
   PubMed Web of Science ®Google Scholar
• J. Xia, B. Allenbrand, and G. Y. Sun. (1998). Dietary supplementation of grape polyphenols and chronic ethanol administration on LDL oxidation and platelet function in rats. Life Sci. 63:383–390.
   PubMed Web of Science ®Google Scholar
• L. J. Yan, E. S. Christians, L. Liu, X. Xiao, R. S. Sohal, and I. J. Benjamin. (2002). Mouse heat shock transcription factor 1 deficiency alters cardiac redox homeostasis and increases mitochondrial oxidative damage. EMBO J. 21:5164–5172.
   PubMed Web of Science ®Google Scholar
• H. Zou, W. J. Henzel, X. Liu, A. Lutschg, and X. Wang. (1997). Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 90:405–413.
   PubMed Web of Science ®Google Scholar