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Research Article

Lead-Induced Stress Response in Endoplasmic Reticulum of Astrocytes in CNS

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Pages 751-757 | Received 16 Oct 2007, Accepted 23 Dec 2007, Published online: 02 Dec 2008

REFERENCES

  • G. Audesirk, D. Shugarts, G. Nelson, and J. Przekwas. 1989. Organic and inorganic lead inhibit neurite growth in vertebrate and invertebrate neurons in culture. In Vitro Cell. Dev. Biol. 25:1121–1128.
  • S. H. Back, M. Schroder, K. Lee, K. Zhang, and R. J. Kaufman. 2005. ER stress signaling by regulated splicing: IRE1/HAC1/XBP1. Methods 35:395–416.
  • M. W. Bradbury, and R. Deane. 1993. Permeability of the blood-brain barrier to lead. Neurotoxicology 14:131–136.
  • J. W. Brewer, and J. A. Diehl. 2000. PERK mediates cell-cycle exit during the mammalian unfolded protein response. Proc. Natl. Acad. Sci. USA 97:12625–12630.
  • J. W. Brewer, L. M. Hendershot, C. J. Sherr, and J. A. Diehl. 1999. Mammalian unfolded protein response inhibits cyclin D1 translation and cell-cycle progression. Proc. Natl. Acad. Sci. USA 96:8505–8510.
  • L. Hendershot, J. Wei, J. Gaut, J. Melnick, S. Aviel, and Y. Argon. 1996. Inhibition of immunoglobulin folding and secretion by dominant negative Bip ATPase mutants. Proc. Natl. Acad. Sci. USA 93:5269–5274.
  • R. J. Kaufman. 1999. Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls. Genes Dev. 13:1211–1233.
  • R. Kim, M. Emi, K. Tanabe, and S. Murakami. 2006. Role of the unfolded protein response in cell death. Apoptosis 11:5–13.
  • Y. Kozutsumi, M. Segal, K. Normington, M. J. Gething, and J. Sambrook. 1988. The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins. Nature 332:462–464.
  • A. L. Laitusis, M. A. Brostrom, and C. O. Brostrom. 1999. The dynamic role of GRP78/BiP in the coordination of mRNA translation with protein processing. J. Biol. Chem. 274:486–493.
  • L. S. Lindahl, L. Bird, M. B. Legare, G. Mikeska, G. R. Bratton, and E. Tiffany-Castiglioni. 1999. Differential ability of astrocyte and neuronal cells to accumulate lead: dependence on cell type and on degree of differentiation. Toxicol. Sci. 50:236–243.
  • E. Little, M. Ramakrishnan, B. Roy, G. Gazit, and A. S. Lee. 1994. The glucose-regulated proteins (GRP78 and GRP94): Functions, gene regulation, and applications. Crit. Rev. Eukaryotic Gene Expression 4:1–18.
  • A. H. Mir, M. L. B. Christopher, P. Jonathan, and L. John. 2000. Induction of vascular endothelial growth factor in human astrocytes by lead. J Biol. Chem. 275:27874–27882.
  • Y. Qian, and E. Tiffany-Castiglioni. 2003. Lead-induced endoplasmic reticulum (ER) stress responses in the nervous system. Neurochem. Res. 28:153–162.
  • Y. Qian, M. H. Falahatpished, Y. Zheng, K. S. Ramos, and E. Tiffany-Castiglioni. 2001. Induction of 78kD glucose-regulated protein (GRP78) expression and redox-regulated transcription factor activity by lead and mercury in C6 rat glioma cells. Neurotox. Res. 3:581–589.
  • Y. Qian, E. D. Harris, Y. Zheng, and E. Tiffany-Castiglioni. 2000. Lead targets GRP78, a molecular chaperone, in C6 rat glioma cells. Toxicol. Appl. Pharmacol. 163:260–266.
  • Y. Qian, G. Mikeska, E. D. Harris, G. R. Bratton, and E. Tiffany-Castiglioni. 1999. Effect of lead exposure and accumulation on copper homeostasis in cultured C6 rat glioma cells. Toxicol. Appl. Pharmacol. 158:41–49.
  • Y. Qian, E. Tiffany-Castiglioni, and E. D. Harris. 1995. Copper transport and kinetics in cultured C6 rat glioma cells. Am. J. Physiol. 269:C892–C898.
  • M. Schroder, and R. J. Kaufman. 2005a. The mammalian unfolded protein response. Annu. Rev. Biochem. 74:739–789.
  • M. Schroder, and R. J. Kaufman. 2005b. ER stress and the unfolded protein response. Mutat. Res. 569:29–63.
  • E. M. Sierra, and E. Tiffany-Castiglioni. 1991. Reduction of glutamine synthetase activity in astrocyte exposed in culture to low levels of inorganic lead. Toxicology 65:295–304.
  • C. Suresh, A. O. Dennis, J. Heinz, M. C. Vemuri, and C. S. Chetty. 2006. Melatonin protection against lead-induced changes in human neruoblastoma cell cultures. Int. J. Toxicol. 25:459–464.
  • E. Tiffany-Castiglioni. 1993. Cell culture models for lead toxicity in neuronal and glial cells. Neurotoxicology 14:513–536.
  • K. J. Travers, C. K. Patil, L. Wodicka, D. J. Lockhart, J. S. Weissman, and P. Walter. 2000. Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation. Cell 101:249–258.
  • H. Q. Wang, Z. X. Du, H. Y. Zhang, and D. X. Gao. 2007. Different induction of GRP78 and CHOP as a predictor of sensitivity to proteasome inhibitors in thyroid cancer cells. Endocrinology 148:3258–3270.
  • X. Z. Wang, H. P. Harding, Y. Zhang, E. M. Jolicoeur, M. Kuroda, and D. Ron. 1998. Cloning of mammalian Ire1 reveals diversity in the ER stress responses. EMBO J. 17:5708–5717.
  • X. Z. Wang, B. Lawson, J. W. Brewer, H. Zinszner, A. Sanjay, L. J. Mi, R. Boorstein, G. Kreibich, L. M. Hendershot, and D. Ron. 1996. Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153). Mol. Cell. Biol. 16:4273–4280.
  • S. K. Wooden, L. J. Li, D. Navarro, I. Qadri, L. Pereira, and A. S. Lee. 1991. Transactivation of the grp78 promoter by malfolded proteins, glycosylation block, and calcium ionophore is mediated through a proximal region containing a CCAAT motif which interacts with CTF/NF-I. Mol. Cell. Biol. 11:5612–5623.
  • Z. W. Zhu, R. L. Yang, G. J. Dong, and Z. Y. Zhao. 2005. Study on the neurotoxic effects of low-level lead exposure in rats. J. Zhejiang Univ. Sci. B 6:686–692.

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