Chemoprevention of Colon Cancer by a Synthetic Curcumin Analog Involves Amelioration of Oxidative Stress

REFERENCES

• Quershi A, Gorey T F, Byme P, Kay E, Mekkever J, Hennessy P J. Oxygen free radical activity in experimental colonic carcinoma. Br J Surg 1994; 81: 1058–1059, [CSA]
   PubMedGoogle Scholar
• Moghadasian M H, Freeman H J, Gadin D V. Endogenous antioxidant status in neoplastic and adjacent tissues in 1,2-dimethylhydrazine-induced colon cancer in rats: effects of olsalazine. Carcinogenesis 1996; 17: 983–987, [PUBMED], [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Tiwari A K. Imbalance in antioxidant defence and human disease: Multiple approach of natural antioxidant therapy. Current Sci 2001; 81: 1179–1187, [CSA]
   Web of Science ®Google Scholar
• Balasenthil S, Ramachandran C R, Nagini S. Prevention of 4-nitroquinoline- 1-oxide-induced rat tongue carcinogenesis by garlic. Fitoterapia 2001; 524–531, [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Arivazhagan S, Balasenthil S, Nagini S. Modulatory effects of garlic and neem leaf extracts on N-methyl-N′ -nitro-N-nitroguanidine (MNNG)-induced oxidative stress in Wistar rats. Cell Biochem Funct 2000; 18: 17–21, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Devasena T, Rajasekaran K N, Menon V P. Bis-1,7-(2-hydroxyphenyl)-hepta-1,6-diene-3,5-dione (a curcumin analog) ameliorates DMH-induced hepatic oxidative stress during colon carcinogenesis. Pharmacol Res 2002; 46: 39–45, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Ray G, Batra S, Shukla N K, Deo S, Raina V, Ashok S, Hussain S A. Lipid peroxidation, free radical production and antioxidant status in breast cancer. Breast Cancer Res Treat 2000; 59: 163–170, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Manoj G P, Thampi B SH, Menon V P, Leelamma S. Influence of dietary fibre from coconut kernel (Cocus nucifera) on the 1,2-dimethylhydrazine-induced lipid peroxidation in rats. J Nutr Biochem 1999; 10: 555–560, [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Zhao Y, Xue Y, Obereley T D, Kiningham K K, Lin S M, Yen H C, Majima H, St. Hines J, Clair D. Over expression of manganese superoxide dismutase suppresses tumor formation by modulation of activator protein-1 signalling in a multistage skin carcinogenesis model. Cancer Res 2001; 61(16)6082–6088, [PUBMED], [INFOTRIEVE], [CSA]
   PubMedGoogle Scholar
• Devasena T, Menon V P. Enhancement of circulatory antioxidants by fenugreek during 1,2-dimethylhydrazine-induced colon carcinogenesis. Biochem Mol Biol Biophys 2002; 6(4)289–292, [CSA]
   PubMedGoogle Scholar
• Pawlega B, Jakubowicz-Gil J, Rzymowska J, Gawron A. The effect of quercetin on apoptosis and necrosis induction in human colon adenocarcinoma cell line LS180. Folia Histochem Cytobiol 2001; 39(2)217–218, [CSA]
   PubMedGoogle Scholar
• Van Leishout E MM, Bedaf M MG, Pieter M, Ekkel C, Nijhoff W A, Pefers W HM. Effects of dietary anticarcinogens on rat gastrointestinal glutathione S-transferase theta 1-1 levels. Carcinogenesis 1998; 19(11)2055–2057, [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Nijhoff W A, Groen G M, Peters W HM. Induction of rat hepatic and intestinal glutathione S-transferase and glutathione by dietary naturally occurring anticarcinogens. Int J Oncol 1993; 3: 1131–1139, [CSA]
   PubMed Web of Science ®Google Scholar
• Dinkova-Kostova A T, Talalay P. Relation of structure of curcumin analogs to their potencies as inducers of phase 2 detoxification enzymes. Carcinogenesis 1999; 20(5)911–914, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Dinesh Babu K V, Rajasekaran K N. Simplified conditions for the synthesis of curcumin I and other curcuminoids. Org Procedure Int 1994; 26: 674–677, [CSA]
   Google Scholar
• Rajakrishnan V, Jayadeep A, Arun O S, Sudhakaran P R, Menon V P. Changes in the prostaglandin levels in alcohol toxicity: Effect of curcumin and N-acetylcysteine. J Nutr Biochem 2000; 11: 509–514, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Yagi K. Lipid peroxides and human disease. Chem Physiol Lipids 1978; 45: 337–351, [CSA], [CROSSREF]
   Web of Science ®Google Scholar
• Ellman G L. Tissue sulphydryl groups. Arch Biochem Biophys 1959; 82: 70–77, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Rotruck J T, Pope A L, Ganther H E, Swanson A B, Hafeman D G, Hoekstra W G. Biochemical roles as a component of glutathione peroxidase. Science 1973; 179: 588–590, [PUBMED], [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Habig W H, Pabst M J, Jakoby W B. Glutathione S-transferase, the first enzymatic step in mercapturic acid formation. J Biol Chem 1974; 249: 7130–7139, [PUBMED], [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Lowry O H, Roseborough N J, Farr A L, Randll A J. Protein measurement with Folin's phenol reagent. J Biol Chem 1951; 193: 265–275, [PUBMED], [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Devasena T, Rajasekaran K N, Gunasekaran G, Viswanathan P, Menon V P. Anticarcinogenic effect of bis-1,7-(2-hydroxyphenyl)-hepta-1,6-diene-3,5-dione, a curcumin analog on DMH-induced colon cancer model. Pharmacol Res 2003; 47: 133–140, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Anto R J, George J, Dinesh Babu K V, Rajasekaran K N, Kuttan R. Antimutagenic and anticarcinogenic activity of natural and synthetic curcuminoids. Mutat Res 1996; 370: 127–131, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Wood A W, Huang M T, Chang R L, Newmark H L, Lehr R E, Yagi H, Sayer J M, Jerina D M, Conney A H. Inhibition of the mutagenicity of bay-region diol epoxides of polycyclic aromatic hydrocarbons by naturally occurring phenols: Exceptional activity of ellagic acid. Proc Natl Acad Sci (USA) 1982; 19: 5513–5517, [CSA]
   Google Scholar
• Hoffman E J, Webster N R, Wiggins P A, Chisholm E M, Glier G R., Leveson S H. Free radical detoxifying systems in human colorectal cancer. Br J Cancer 1995; 51: 127–129, [CSA]
   Google Scholar
• Longo W E, Grossman E M, Erickson B, Panosar N, Mazuski J E, Kaminski D L. The effect of phospholipase A2 inhibitors on proliferation and apoptosis of marine intestinal cells. J Surg Res 1999; 84: 51–56, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Devasena T, Gunasekaran G, Viswanathan P, Menon V P. Chemoprevention of 1,2-dimethylhydrazine-induced colon carcinogenesis by seeds of Trigonella foenum graecum L. Biol Bratis 2003; 58: 357–367, [CSA]
   Google Scholar
• Nalini N, Sabitha K, Chitra P, Viswanathan P, Menon V P. Histopathological and lipid changes in experimental colon cancer: Effect of coconut kernel and red chilli powder. Ind J Exp Biol 1997; 35: 964–971, [CSA]
   PubMedGoogle Scholar
• Cheesman H, Collins H, Proudfoot K, Slater T F, Burton W, Webb A C, Ingold K U. Studies on lipid peroxidation in normal and tumor tissues. J Biol Chem 1986; 235: 507–514, [CSA]
   Google Scholar
• Tanaka T, Kawabata K, Kakumoto M, Hara A, Murakami A, Kuki W, Takahashi Y, Yonei H, Maeda M, Ota T, Odshima S, Yamane T, Koshimizu K, Ohigashi H. Citrus auraptene exerts dose dependent chemopreventive activity in rat large bowel tumorigenesis: The inhibition correlates with suppression of cell proliferation and lipid peroxidation and with induction of Phase II drug metabolising enzymes. Cancer Res 1998; 58: 2550–2556, [PUBMED], [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Barrera G, Brossa O, Fazio A M, Farace M G, Paradisi C, Gravela E. Effects of 4-hydroxynonenal, a product of lipid peroxidation on cell proliferation and ornithine decarboxylase activity. Free Rad Res Commun 1991; 14: 81–89, [CSA]
   PubMed Web of Science ®Google Scholar
• Borroz K I, Beutler T M, Ealon D L. Modulation of γ -glutamylcysteine synthetase large subunit mRNA expression by butylated hydroxyanisole. Toxicol Appl Pharmacol 1994; 126: 150–155, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Forman H J, Lin R M, Shi M M. Biothiols in health and disease. Glutathione synthesis in oxidative stress, L Packer, E Cadenas. Mercked Dekker, New York, 189–212
   Google Scholar
• Van Leishout E MM, Roelofs H MJ, Dekker R, Mulder C JJ, Wobber T, Janson B MJ, Peters W HM. Polymorphic expression of the glutathione S-transferase P1 gene and its susceptibility to Barret's oesaphagus andoesophageal carcinoma. Cancer Research 1995; 59: 586–589, [CSA]
   Google Scholar
• Fiala E S. Investigations into the metabolism and mode of action of colon carcinogens 1,2-dimethylhydrazine and azoxymethane. Cancer 1977; 40(5)2436–2445, [PUBMED], [INFOTRIEVE], [CSA]
   PubMedGoogle Scholar
• Ketterer B. Protective role of glutathione and glutathione transferases in mutagenesis and carcinogenesis. Mutat Res 1988; 202: 343–361, [PUBMED], [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar