1,738
Views
0
CrossRef citations to date
0
Altmetric
Research Article

Assessment of the Relationship Between Genetic Determinants of Obesity, Unhealthy Eating Habits and Chronic Obstructive Pulmonary Disease: A Mendelian Randomisation Study

, , , , , & show all
Article: 2309236 | Received 15 Nov 2023, Accepted 18 Jan 2024, Published online: 13 Feb 2024

Reference

  • Celli B, Fabbri L, Criner G, et al. Definition and nomenclature of chronic obstructive pulmonary disease: time for its revision. Am J Respir Crit Care Med. 2022;206(11):1–7. doi: 10.1164/rccm.202204-0671PP.
  • Sin DD, Anthonisen NR, Soriano JB, et al. Mortality in COPD: role of comorbidities. Eur Respir J. 2006;28(6):1245–1257. doi: 10.1183/09031936.00133805.
  • Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med. 2006;3(11):e442. doi: 10.1371/journal.pmed.0030442.
  • Wu T, Jahangir MR, Mensink-Bout SM, et al. Visceral adiposity and respiratory outcomes in children and adults: a systematic review. Int J Obes (Lond). 2022;46(6):1083–1100. doi: 10.1038/s41366-022-01091-6.
  • Pinto LM, Alghamdi M, Benedetti A, et al. Derivation and validation of clinical phenotypes for COPD: a systematic review. Respir Res. 2015;16(1):50. doi: 10.1186/s12931-015-0208-4.
  • Parvizian MK, Dhaliwal M, Li J, et al. Relationship between dietary patterns and COPD: a systematic review and meta-analysis. ERJ Open Res. 2020;6(2):00168-2019. doi: 10.1183/23120541.00168-2019.
  • Ng R, Sutradhar R, Yao Z, et al. Smoking, drinking, diet and physical activity-modifiable lifestyle risk factors and their associations with age to first chronic disease. Int J Epidemiol. 2020;49(1):113–130. doi: 10.1093/ije/dyz078.
  • Sekula P, Del Greco M F, Pattaro C, et al. Mendelian randomization as an approach to assess causality using observational data. J Am Soc Nephrol. 2016;27(11):3253–3265. doi: 10.1681/ASN.2016010098.
  • Birney E. Mendelian randomization. Cold Spring Harb Perspect Med. 2022;12(4):a041302. doi: 10.1101/cshperspect.a041302.
  • Clarke T-K, Adams MJ, Davies G, et al. Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK biobank (N = 112 117). Mol Psychiatry. 2017;22(10):1376–1384. doi: 10.1038/mp.2017.153.
  • Palmer TM, Lawlor DA, Harbord RM, et al. Using multiple genetic variants as instrumental variables for modifiable risk factors. Stat Methods Med Res. 2012;21(3):223–242. doi: 10.1177/0962280210394459.
  • Wang S, Zhu H, Pan L, et al. Systemic inflammatory regulators and risk of acute-on-chronic liver failure: a bidirectional mendelian-randomization study. Front Cell Dev Biol. 2023;11:1125233. doi: 10.3389/fcell.2023.1125233.
  • Venkatesan P. GOLD COPD report: 2023 update. Lancet Respir Med. 2023;11(1):18. doi: 10.1016/S2213-2600(22)00494-5.
  • Singh D, Agusti A, Anzueto A, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive lung disease: the GOLD science committee report 2019. Eur Respir J. 2019;53(5):1900164. doi: 10.1183/13993003.00164-2019.
  • Yousuf A, McAuley H, Elneima O, et al. The different phenotypes of COPD. Br Med Bull. 2021;137(1):82–97. doi: 10.1093/bmb/ldaa043.
  • Agustí A, Celli BR, Criner GJ, et al. Global initiative for chronic obstructive lung disease 2023 report: GOLD executive summary. Arch Bronconeumol. 2023;59(4):232–248. doi: 10.1016/j.arbres.2023.02.009.
  • Viegi G, Maio S, Fasola S, et al. Global burden of chronic respiratory diseases. J Aerosol Med Pulm Drug Deliv. 2020;33(4):171–177. doi: 10.1089/jamp.2019.1576.
  • Luis López-Campos J, Tan W, Soriano JB. Global burden of COPD. Respirology. 2016;21(1):14–23. doi: 10.1111/resp.12660.
  • Foreman KJ, Marquez N, Dolgert A, et al. Forecasting life expectancy, years of life lost, and all-cause and cause-specific mortality for 250 causes of death: reference and alternative scenarios for 2016-40 for 195 countries and territories. Lancet. 2018;392(10159):2052–2090. doi: 10.1016/S0140-6736(18)31694-5.
  • Gerstein E, Bierbrier J, Whitmore GA, et al. Impact of undiagnosed COPD and asthma on symptoms, quality of life, healthcare utilization and work productivity. Am J Respir Crit Care Med. 2023;208(12):1271–1282. doi: 10.1164/rccm.202307-1264OC.
  • Goren A, Gupta S, Dong P, et al. Burden of smoking among adults with COPD, chronic bronchitis, and emphysema in urban China. Int J Clin Pract. 2015;69(9):1015–1028. doi: 10.1111/ijcp.12680.
  • Lelieveld J, Evans JS, Fnais M, et al. The contribution of outdoor air pollution sources to premature mortality on a global scale. Nature. 2015;525(7569):367–371. doi: 10.1038/nature15371.
  • Manian P. Chronic obstructive pulmonary disease classification, phenotypes and risk assessment. J Thorac Dis. 2019;11(Suppl 14):S1761–S1766. doi: 10.21037/jtd.2019.05.10.
  • Zhen G, Yingying L, Jingcheng D. Drug therapies for COPD: a bibliometric review from 1980 to 2021. Front Pharmacol. 2022;13:820086. doi: 10.3389/fphar.2022.820086.
  • McDonald VM, Wood LG, Holland AE, et al. Obesity in COPD: to treat or not to treat? Expert Rev Respir Med. 2017;11(2):81–83. doi: 10.1080/17476348.2017.1267570.
  • Hanson C, LeVan T. Obesity and chronic obstructive pulmonary disease: recent knowledge and future directions. Curr Opin Pulm Med. 2017;23(2):149–153. doi: 10.1097/MCP.0000000000000354.
  • Beijers RJHCG, Steiner MC, Schols AMWJ. The role of diet and nutrition in the management of COPD. Eur Respir Rev. 2023;32(168):230003. doi: 10.1183/16000617.0003-2023.
  • O’Donnell DE, Ciavaglia CE, Neder JA. When obesity and chronic obstructive pulmonary disease collide. Physiological and clinical consequences. Ann Am Thorac Soc. 2014;11(4):635–644. doi: 10.1513/AnnalsATS.201312-438FR.
  • Zutler M, Singer JP, Omachi TA, et al. Relationship of obesity with respiratory symptoms and decreased functional capacity in adults without established COPD. Prim Care Respir J. 2012;21(2):194–201. doi: 10.4104/pcrj.2012.00028.
  • Dreher M, Kabitz H-J. Impact of obesity on exercise performance and pulmonary rehabilitation. Respirology. 2012;17(6):899–907. doi: 10.1111/j.1440-1843.2012.02151.x.
  • Poulain M, Doucet M, Major GC, et al. The effect of obesity on chronic respiratory diseases: pathophysiology and therapeutic strategies. CMAJ. 2006;174(9):1293–1299. doi: 10.1503/cmaj.051299.
  • Wouters EFM. Obesity and metabolic abnormalities in chronic obstructive pulmonary disease. Ann Am Thorac Soc. 2017;14(Supplement_5):S389–S394. doi: 10.1513/AnnalsATS.201705-371AW.
  • Wang X, Liang Q, Li Z, et al. Body composition and COPD: a new perspective. Int J Chron Obstruct Pulmon Dis. 2023;18:79–97. doi: 10.2147/COPD.S394907.
  • Zhang X, Chen H, Gu K, et al. Association of body mass index and abdominal obesity with the risk of airflow obstruction: national health and nutrition examination survey (NHANES) 2007-2012. COPD. 2022;19(1):99–108. doi: 10.1080/15412555.2022.2032627.
  • Lavie CJ, Sanchis-Gomar F, Neeland IJ. Body composition and pulmonary diseases. COPD. 2022;19(1):262–264. doi: 10.1080/15412555.2022.2070465.
  • Zuccolo L, Holmes MV. Commentary: mendelian randomization-inspired causal inference in the absence of genetic data. Int J Epidemiol. 2017;46(3):962–965. doi: 10.1093/ije/dyw327.
  • Lambert AA, Putcha N, Bradley Drummond M, COPDGene Investigators., et al. Obesity is associated with increased morbidity in moderate to severe COPD. Chest. 2017;151(1):68–77. doi: 10.1016/j.chest.2016.08.1432.
  • Zammit C, Liddicoat H, Moonsie I, et al. Obesity and respiratory diseases. Int J Gen Med. 2010;3:335–343. doi: 10.2147/IJGM.S11926.
  • Şahin H, Naz İ, Varol Y, et al. The effect of obesity on dyspnea, exercise capacity, walk work and workload in patients with COPD. Tuberk Toraks. 2017;65(3):202–209. doi: 10.5578/tt.57228.
  • Larsson SC, Burgess S. Causal role of high body mass index in multiple chronic diseases: a systematic review and meta-analysis of mendelian randomization studies. BMC Med. 2021;19(1):320. doi: 10.1186/s12916-021-02188-x.
  • Shi Z, Dal Grande E, Taylor AW, et al. Association between soft drink consumption and asthma and chronic obstructive pulmonary disease among adults in Australia. Respirology. 2012;17(2):363–369. doi: 10.1111/j.1440-1843.2011.02115.x.
  • Greene CC, Bradley KA, Bryson CL, et al. The association between alcohol consumption and risk of COPD exacerbation in a veteran population. Chest. 2008;134(4):761–767. doi: 10.1378/chest.07-3081.