REFERENCES
- Bailly M, Yan L, Whitesides G M, Condeelis J S, Segall J E. Regulation of protrusion shape and adhesion to the substratum during chemotactic responses of mammalian carcinoma cells. Exp Cell Res 1998; 241: 285–299, [PUBMED], [INFOTRIEVE], [CSA]
- Heath J P, Holifield B F. Cell locomotion: New research tests old ideas on membrane and cytoskeletal flow. Cell Motil Cytoskeleton 1991; 18: 245–257, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Lauffenburger D A, Horwitz A F. Cell migration: A physically integrated molecular process. Cell 1996; 84: 359–369, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Ridley A J, Schwartz M A, Burridge K, Firtel R A, Ginsberg M H, Borisy G, Parsons J T, Horwitz A R. Cell migration: Integrating signals from front to back. Science 2003; 302: 1704–1709, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- DePasquale J A, Izzard C S. Evidence for an actin-containing cytoplasmic precursor of the focal contact and the timing of incorporation of vinculin at the focal contact. J Cell Biol 1987; 105: 2803–2809, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Izzard C S. A precursor of the focal contact in cultured fibroblasts. Cell Motil Cytoskeleton 1988; 10: 137–142, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Geiger B, Bershadsky A, Pankov R, Yamada K M. Transmembrane crosstalk between the extracellular matrix—cytoskeleton crosstalk. Nat Rev Mol Cell Biol 2001; 2: 793–805, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Geiger B, Bershadsky A. Assembly and mechanosensory function of focal contacts. Curr Opin Cell Biol 2001; 13: 584–592, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Nobes C D, Hall A. Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 1995; 81: 53–62, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Zaidel-Bar R, Ballestrem C, Kam Z, Geiger B. Early molecular events in the assembly of matrix adhesions at the leading edge of migrating cells. J Cell Sci 2003; 116: 4605–4613, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Belkin A M, Koteliansky V E. Interaction of iodinated vinculin, metavinculin and alpha-actinin with cytoskeletal proteins. FEBS Lett 1987; 220: 291–294, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Burridge K, Fath K, Kelly T, Nuckolls G, Turner C. Focal adhesions: Transmembrane junctions between the extracellular matrix and the cytoskeleton. Annu Rev Cell Biol 1988; 4: 487–525, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Burridge K, Mangeat P. An interaction between vinculin and talin. Nature 1984; 308: 744–746, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Johnson R P, Craig S W. F-actin binding site masked by the intramolecular association of vinculin head and tail domains. Nature 1995; 373: 261–264, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Kroemker M, Rudiger A H, Jockusch B M, Rudiger M. Intramolecular interactions in vinculin control alpha-actinin binding to the vinculin head. FEBS Lett 1994; 355: 259–262, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Menkel A R, Kroemker M, Bubeck P, Ronsiek M, Nikolai G, Jockusch B M. Characterization of an F-actin-binding domain in the cytoskeletal protein vinculin. J Cell Biol 1994; 126: 1231–1240, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Turner C E, Glenney J R, Jr, Burridge K. Paxillin: A new vinculin-binding protein present in focal adhesions. J Cell Biol 1990; 111: 1059–1068, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Craig S W, Chen H. Lamellipodia protrusion: Moving interactions of vinculin and Arp2/3. Curr Biol 2003; 13: R236–238, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- DeMali K A, Barlow C A, Burridge K. Recruitment of the Arp2/3 complex to vinculin: Coupling membrane protrusion to matrix adhesion. J Cell Biol 2002; 159: 881–891, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Ridley A J. Rho GTPases and cell migration. J Cell Sci 2001; 114: 2713–2722, [PUBMED], [INFOTRIEVE], [CSA]
- Wozniak M A, Kwong L, Chodniewicz D, Klemke R L, Keely P J. R-Ras controls membrane protrusion and cell migration through the spatial regulation of Rac and Rho. Mol Biol Cell 2005; 16: 84–96, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Billuart P, Winter C G, Maresh A, Zhao X, Luo L. Regulating axon branch stability: The role of p190 RhoGAP in repressing a retraction signaling pathway. Cell 2001; 107: 195–207, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Arthur W T, Burridge K. RhoA inactivation by p190RhoGAP regulates cell spreading and migration by promoting membrane protrusion and polarity. Mol Biol Cell 2001; 12: 2711–2720, [PUBMED], [INFOTRIEVE], [CSA]
- Borbiev T, Nurmukhambetova S, Liu F, Verin A D, Garcia J G. Introduction of C3 exoenzyme into cultured endothelium by lipofectamine. Anal Biochem 2000; 285: 260–264, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Sekine A, Fujiwara M, Narumiya S. Asparagine residue in the rho gene product is the modification site for botulinum ADP-ribosyltransferase. J Biol Chem 1989; 264: 8602–8605, [PUBMED], [INFOTRIEVE], [CSA]
- Wilde C, Genth H, Aktories K, Just I. Recognition of RhoA by Clostridium botulinum C3 exoenzyme. J Biol Chem 2000; 275: 16478–16483, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Manser E, Chong C, Zhao Z S, Leung T, Michael G, Hall C, Lim L. Molecular cloning of a new member of the p21-Cdc42/Rac-activated kinase (PAK) family. J Biol Chem 1995; 270: 25070–25078, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Ishizaki T, Maekawa M, Fujisawa K, Okawa K, Iwamatsu A, Fujita A, Watanabe N, Saito Y, Kakizuka A, Morii N, et al. The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase. Embo J 1996; 15: 1885–1893, [PUBMED], [INFOTRIEVE], [CSA]
- Feng J, Ito M, Ichikawa K, Isaka N, Nishikawa M, Hartshorne D J, Nakano T. Inhibitory phosphorylation site for Rho-associated kinase on smooth muscle myosin phosphatase. J Biol Chem 1999; 274: 37385–37390, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Kawano Y, Fukata Y, Oshiro N, Amano M, Nakamura T, Ito M, Matsumura F, Inagaki M, Kaibuchi K. Phosphorylation of myosin-binding subunit (MBS) of myosin phosphatase by Rho-kinase in vivo. J Cell Biol 1999; 147: 10237–1038, [CSA], [CROSSREF]
- Amano M, Ito M, Kimura K, Fukata Y, Chihara K, Nakano T, Matsuura Y, Kaibuchi K. Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase). J Biol Chem 1996; 271: 20246–20249, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Kureishi Y, Kobayashi S, Amano M, Kimura K, Kanaide H, Nakano T, Kaibuchi K, Ito M. Rho-associated kinase directly induces smooth muscle contraction through myosin light chain phosphorylation. J Biol Chem 1997; 272: 12257–12260, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Totsukawa G, Yamakita Y, Yamashiro S, Hartshorne D J, Sasaki Y, Matsumura F. Distinct roles of ROCK (Rho-kinase) and MLCK in spatial regulation of MLC phosphorylation for assembly of stress fibers and focal adhesions in 3T3 fibroblasts. J Cell Biol 2000; 150: 797–806, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Amano M, Chihara K, Nakamura N, Fukata Y, Yano T, Shibata M, Ikebe M, Kaibuchi K. Myosin II activation promotes neurite retraction during the action of Rho and Rho-kinase. Genes Cells 1998; 3: 177–188, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Chihara K, Amano M, Nakamura N, Yano T, Shibata M, Tokui T, Ichikawa H, Ikebe R, Ikebe M, Kaibuchi K. Cytoskeletal rearrangements and transcriptional activation of c-fos serum response element by Rho-kinase. J Biol Chem 1997; 272: 25121–25127, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Matsui T, Maeda M, Doi Y, Yonemura S, Amano M, Kaibuchi K, Tsukita S. Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association. J Cell Biol 1998; 140: 647–657, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Worthylake R A, Burridge K. RhoA and ROCK promote migration by limiting membrane protrusions. J Biol Chem 2003; 278: 13578–13584, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Ghosh M, Song X, Mouneimne G, Sidani M, Lawrence D S, Condeelis J S. Cofilin promotes actin polymerization and defines the direction of cell motility. Science 2004; 304: 743–746, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Maekawa M, Ishizaki T, Boku S, Watanabe N, Fujita A, Iwamatsu A, Obinata T, Ohashi K, Mizuno K, Narumiya S. Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase. Science 1999; 285: 895–898, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Yang N, Higuchi O, Ohashi K, Nagata K, Wada A, Kangawa K, Nishida E, Mizuno K. Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization. Nature 1998; 393: 809–812, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Ishizaki T, Uehata M, Tamechika I, Keel J, Nonomura K, Maekawa M, Narumiya S. Pharmacological properties of Y-27632, a specific inhibitor of rho-associated kinases. Mol Pharmacol 2000; 57: 976–983, [PUBMED], [INFOTRIEVE], [CSA]
- Uehata M, Ishizaki T, Satoh H, Ono T, Kawahara T, Morishita T, Tamakawa H, Yamagami K, Inui J, Maekawa M, et al. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature 1997; 389: 990–994, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Chen B H, Tzen J T, Bresnick A R, Chen H C. Roles of Rho-associated kinase and myosin light chain kinase in morphological and migratory defects of focal adhesion kinase-null cells. J Biol Chem 2002; 277: 33857–33863, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Strickland S, Mahdavi V. The induction of differentiation in teratocarcinoma stem cells by retinoic acid. Cell 1978; 15: 393–403, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Dahl S C, Grabel L B. Altered accumulations of fibronectin are not dependent on fibronectin modifications during the differentiation of F-9 teratocarcinoma stem cells. Exp Cell Res 1988; 176: 234–247, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Grabel L, Becker S, Lock L, Maye P, Zanders T. Using EC and ES cell culture to study early development: Recent observations on Indian hedgehog and Bmps. Int J Dev Biol 1998; 42: 917–925, [PUBMED], [INFOTRIEVE], [CSA]
- Gardner R L. Origin and differentiation of extraembryonic tissues in the mouse. Int Rev Exp Pathol 1983; 24: 63–133, [PUBMED], [INFOTRIEVE], [CSA]
- Grabel L B, Casanova J E. The outgrowth of parietal endoderm from mouse teratocarcinoma stem-cell embryoid bodies. Differentiation 1986; 32: 67–73, [PUBMED], [INFOTRIEVE], [CSA]
- Rossant J, Papaioannou V E, Lawson K, Fraser S, Copp A. NIEHS/EPA Workshops. Cell lineages. Reprod Toxicol 1997; 11: 317–319, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Coll J L, Ben-Ze'ev A, Ezzell R M, Rodriguez Fernandez J L, Baribault H, Oshima R G, Adamson E D. Targeted disruption of vinculin genes in F9 and embryonic stem cells changes cell morphology, adhesion, and locomotion. Proc Natl Acad Sci USA 1995; 92: 9161–9165, [PUBMED], [INFOTRIEVE], [CSA]
- Volberg T, Geiger B, Kam Z, Pankov R, Simcha I, Sabanay H, Coll J L, Adamson E, Ben-Ze'ev A. Focal adhesion formation by F9 embryonal carcinoma cells after vinculin gene disruption. J Cell Sci 1995; 108(Pt 6)2253–2260, [PUBMED], [INFOTRIEVE], [CSA]
- Subauste M C, Pertz O, Adamson E D, Turner C E, Junger S, Hahn K M. Vinculin modulation of paxillin-FAK interactions regulates ERK to control survival and motility. J Cell Biol 2004; 165: 371–381, [PUBMED], [INFOTRIEVE], [CSA]
- Ishibe S, Joly D, Liu Z X, Cantley L G. Paxillin serves as an ERK-regulated scaffold for coordinating FAK and Rac activation in epithelial morphogenesis. Mol Cell 2004; 16: 257–267, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Webb D J, Donais K, Whitmore L A, Thomas S M, Turner C E, Parsons J T, Horwitz A F. FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly. Nat Cell Biol 2004; 6: 154–161, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Jiang R, Grabel L B. Function and differential regulation of the alpha 6 integrin isoforms during parietal endoderm differentiation. Exp Cell Res 1995; 217: 195–204, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Zamir E, Geiger B. Molecular complexity and dynamics of cell-matrix adhesions. J Cell Sci 2001; 114: 3583–3590, [PUBMED], [INFOTRIEVE], [CSA]
- Gluck U, Kwiatkowski D J, Ben-Ze'ev A. Suppression of tumorigenicity in simian virus 40-transformed 3T3 cells transfected with alpha-actinin cDNA. Proc Natl Acad Sci U S A 1993; 90: 383–387, [PUBMED], [INFOTRIEVE], [CSA]
- Knudsen K A, Soler A P, Johnson K R, Wheelock M J. Interaction of alpha-actinin with the cadherin/catenin cell-cell adhesion complex via alpha-catenin. J Cell Biol 1995; 130: 67–77, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Pavalko F M, Schneider G, Burridge K, Lim S S. Immunodetection of alpha-actinin in focal adhesions is limited by antibody inaccessibility. Exp Cell Res 1995; 217: 534–540, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Clow P A, McNally J G. In vivo observations of myosin II dynamics support a role in rear retraction. Mol Biol Cell 1999; 10: 1309–1323, [PUBMED], [INFOTRIEVE], [CSA]
- Kolega J. Asymmetric distribution of myosin IIB in migrating endothelial cells is regulated by a rho-dependent kinase and contributes to tail retraction. Mol Biol Cell 2003; 14: 4745–4757, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Riveline D, Zamir E, Balaban N Q, Schwarz U S, Ishizaki T, Narumiya S, Kam Z, Geiger B, Bershadsky A D. Focal contacts as mechanosensors: Externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism. J Cell Biol 2001; 153: 1175–1186, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Laukaitis C M, Webb D J, Donais K, Horwitz A F. Differential dynamics of alpha 5 integrin, paxillin, and alpha-actinin during formation and disassembly of adhesions in migrating cells. J Cell Biol 2001; 153: 1427–1440, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Webb D J, Brown C M, Horwitz A F. Illuminating adhesion complexes in migrating cells: Moving toward a bright future. Curr Opin Cell Biol 2003; 15: 614–620, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Totsukawa G, Wu Y, Sasaki Y, Hartshorne D J, Yamakita Y, Yamashiro S, Matsumura F. Distinct roles of MLCK and ROCK in the regulation of membrane protrusions and focal adhesion dynamics during cell migration of fibroblasts. J Cell Biol 2004; 164: 427–439, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- DesMarais V, Macaluso F, Condeelis J, Bailly M. Synergistic interaction between the Arp2/3 complex and cofilin drives stimulated lamellipod extension. J Cell Sci 2004; 117: 3499–3510, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Ishibe S, Joly D, Zhu X, Cantley L G. Phosphorylation-dependent paxillin-ERK association mediates hepatocyte growth factor-stimulated epithelial morphogenesis. Mol Cell 2003; 12: 1275–1285, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]