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Original

The Drosophila Innexin7 Gap Junction Protein Is Required for Development of the Embryonic Nervous System

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Pages 155-167 | Received 29 Oct 2007, Accepted 14 Dec 2007, Published online: 11 Jul 2009

REFERENCES

  • Barbe M T, Monyer H, Bruzzone R. Cell-cell communication beyond connexins: the pannexin channels. Physiology 2006; 21: 103–114
  • Bauer R, Lehmann C, Hoch M. Gastrointestinal development in the Drosophila embryo requires the activity of innexin gap junction channel proteins. Cell Commun Adhes 2001; 8: 307–310
  • Bauer R, Lehmann C, Fuss B, Eckardt F, Hoch M. The Drosophila gap junction channel gene innexin 2 controls foregut development in response to Wingless signalling. J Cell Sci 2002; 115: 1859–1860, (Pt 9)
  • Bauer R, Lehmann C, Martini J, Eckardt F, Hoch M. Gap junction channel protein innexin 2 is essential for epithelial morphogenesis in the Drosophila embryo. Mol Biol Cell 2004; 15: 2992–3004
  • Bauer R, Löer B, Ostrowski K, Martini J, Weimbs A, Lechner H, Hoch M. Intercellular communication: The Drosophila innexin multiprotein family of gap junction proteins. Chem Biol 2005; 12: 515–526
  • Brand A H, Perrimon N. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 1993; 118: 401–415
  • Brand A H, Manoukian A S, Perrimon N. Ectopic expression in Drosophila. Methods Cell Biol 1994; 44: 635–654
  • Chuang C F, Vanhoven M K, Fetter R D, Verselis V K, Bargmann C I. An innexin-dependent cell network establishes left-right neuronal asymmetry in C elegans. Cell 2007; 129: 787–799
  • Chu-LaGraff Q, Wright D M, McNeil L K, Doe C Q. The prospero gene encodes a divergent homeodomain protein that controls neuronal identity in Drosophila. Development 1991; 79–85, Suppl 2
  • Curtin K D, Zhang Z, Wyman R J. Gap junction proteins are not interchangeable in development of neural function in the Drosophila visual system. J Cell Sci 2002; 115: 3379–3388, (Pt 17)
  • Doe C Q, Chu-LaGraff Q, Wright D M, Scott M P. The prospero gene specifies cell fates in the Drosophila central nervous system. Cell 1991; 65(3)451–464
  • Fuss B, Hoch M. Drosophila endoderm development requires a novel homeobox gene which is a target of Wingless and Dpp signalling. Mech Dev 1998; 79: 83–97
  • Fuss B, Becker T, Zinke I, Hoch M. The cytohesin Steppke is essential for insulin signalling in Drosophila. Nature 2006; 444: 945–948
  • Giesen K, Hummel T, Stollewerk A, Harrison S, Travers A, Klämbt C. Glial development in the Drosophila CNS requires concomitant activation of glial and repression of neuronal differentiation genes. Development 1997; 124: 2307–2316
  • Gilboa L, Forbes A, Tazuke S I, Fuller M T, Lehmann R. Germ line stem cell differentiation in Drosophila requires gap junctions and proceeds via an intermediate state. Development 2003; 130: 6625–6634
  • Goodenough D A, Goliger J A, Paul D L. Connexins, connexons, and intercellular communication. Annu Rev Biochem 1996; 65: 475–502
  • Grenningloh G, Rehm E J, Goodman C S. Genetic analysis of growth cone guidance in Drosophila: Fasciclin II functions as a neuronal recognition molecule. Cell 1991; 67: 45–57
  • Hartenstein V, Campos-Ortéga J A. The Embryonic Development of Drosophila melanogaster, 1st edition. Springer, Berlin 1984; 1091–1201
  • Hummel T, Krukkert K, Roos J, Davis G, Klämbt C. Drosophila Futsch/22C10 is a MAP1B-like protein required for dendritic and axonal development. Neuron 2000; 26: 357–370
  • Jacobs K, Todman M G, Allen M J, Davies J A, Bacon J P. Synaptogenesis in the giant-fibre system of Drosophila: Interaction of the giant fibre and its major motorneuronal target. Development 2000; 127: 5203–5212
  • Klämbt C, Jacobs J R, Goodman C S. The midline of the Drosophila central nervous system: A model for the genetic analysis of cell fate, cell migration, and growth cone guidance. Cell 1991; 64: 801–815
  • Klämbt C, Goodman C S. The diversity and pattern of glia during axon pathway formation in the Drosophila embryo. Glia 1991; 4: 205–213
  • Klämbt C, Goodman C S. Role of the midline glia and neurons in the formation of the axon commissures in the central nervous system of the Drosophila embryo. Ann N Y Acad Sci 1991; 633: 142–159
  • Krishnan S N, Frei E, Swain G P, Wyman R J. Passover: A gene required for synaptic connectivity in the giant fiber system of Drosophila. Cell 1993; 73: 967–977
  • Lechner H, Josten F, Fuss B, Bauer R, Hoch M. Cross regulation of intercellular gap junction communication and paracrine signaling pathways during organogenesis in Drosophila. Dev Biol. 2007; 310: 23–34
  • Lee Y S, Carthew R W. Making a better RNAi vector for Drosophila: Use of intron spacers. Methods. 2003; 30: 322–329
  • Lehmann C, Lechner H, Löer B, Knieps M, Herrmann S, Famulok M, Bauer R, Hoch M. Heteromerization of innexin gap junction proteins regulates epithelial tissue organization in Drosophila. Mol Biol Cell 2006; 17: 1676–1685
  • Locovei S, Bao L, Dahl G. Pannexin 1 in erythrocytes: Function without a gap. Proc Natl Acad Sci U S A 2006; 103: 7655–7659
  • Martin P E, Evans W H. Incorporation of connexins into plasma membranes and gap junctions. Cardiovas. Res 2004; 62: 378–387
  • Matsuzaki F, Koizumi K, Hama C, Yoshioka T, Nabeshima Y. Cloning of the Drosophila prospero gene and its expression in ganglion mother cells. Biochem Biophys Res Commun. 1992; 182: 1326–1332
  • Panchin Y, Kelmanson I, Matz M, Lukyanov K, Usman N, Lukyanov S. A ubiquitous family of putative gap junction molecules. Curr. Biol 2000; 10: R473–R474
  • Pankratz M J, Hoch M. Control of epithelial morphogenesis by cell signaling and integrin molecules in the Drosophila foregut. Development. 1995; 121: 1885–1898
  • Phelan P, Nakagawa M, Wilkin M B, Moffat K G, O'Kane C J, Davies J A, Bacon J P. Mutations in shaking-B prevent electrical synapse formation in the Drosophila giant fiber system. J Neurosci 1996; 16: 1101–1113
  • Phelan P, Bacon J P, Davies J A, Stebbings L A, Todman M G, Avery L, Baines R A, Barnes T M, Ford C, Hekimi S, Lee R, Shaw J E, Starich T A, Curtin K D, Sun Y A, Wyman R J. Innexins: A family of invertebrate gap-junction proteins. Trends Genet 1998; 14: 348–349
  • Phelan P, Starich T A. Innexins get into the gap. Bioessays 2001; 23: 388–396
  • Phelan P. Innexins: members of an evolutionarily conserved family of gap-junction proteins. Biochim Biophys Acta 2005; 711: 225–245
  • Rothberg J M, Hartley D A, Walther Z, Artavanis-Tsakonas S. slit: An EGF-homologous locus of D. melanogaster involved in the development of the embryonic central nervous system. Cell. 1988; 55: 1047–1059
  • Rubin G M, Spradling A C. Genetic transformation of Drosophila with transposable element vectors. Science. 1982; 218: 348–353
  • Scholz H, Sadlowski E, Klaes A, Klambt C. Control of midline glia development in the embryonic Drosophila CNS. Mech. Dev 1997; 62: 79–91
  • Seeger M, Tear G, Ferres-Marco D, Goodman C S. Mutations affecting growth cone guidance in Drosophila: Genes necessary for guidance toward or away from the midline. Neuron 1993; 10: 409–426
  • Segretain D, Falk M M. Regulation of connexin biosynthesis, assembly, gap junction formation, and removal. Biochim Biophys Acta 2004; 1662: 3–21
  • Shimohigashi M, Meinertzhagen I A. The shaking B gene in Drosophila regulates the number of gap junctions between photoreceptor terminals in the lamina. J Neurobiol 1998; 35: 105–117
  • Stebbings L A, Todman M G, Phelan P, Bacon J P, Davies J A. Two Drosophila innexins are expressed in overlapping domains and cooperate to form gap-junction channels. Mol Biol Cell. 2000; 11: 2459–2470
  • Taghert P H, Bastiani M J, Ho R K, Goodman C S. Guidance of pioneer growth cones: Filopodial contacts and coupling revealed with an antibody to Lucifer Yellow. Dev Biol. 1982; 94: 391–399
  • Tazuke S I, Schulz C, Gilboa L, Fogarty M, Mahowald A P, Guichet A, Ephrussi A, Wood C G, Lehmann R, Fuller M T. A germline-specific gap junction protein required for survival of differentiating early germ cells. Development 2002; 129: 2529–2539
  • Vaessin H, Grell E, Wolff E, Bier E, Jan L Y, Jan Y N. Prospero is expressed in neuronal precursors and encodes a nuclear protein that is involved in the control of axonal outgrowth in Drosophila. Cell. 1991; 67: 941–953
  • Watanabe T, Kankel D R. he l(1)ogre gene of Drosophila melanogaster is expressed in postembryonic neuroblasts. Dev. Biol 1992; 152: 172–183
  • Wei C J, Xu X, Lo C W. Connexins and cell signaling in development and disease. Annu Rev Cell Dev Biol 2004; 20: 811–838
  • Wolszon L R, Gao W Q, Passani M B, Macagno E R. Growth cone “collapse” in vivo: Are inhibitory interactions mediated by gap junctions?. J Neurosci. 1994; 14: 999–1010, (3 Pt 1)
  • Yuasa Y, Okabe M, Yoshikawa S, Tabuchi K, Xiong W C, Hiromi Y, Okano H. Drosophila homeodomain protein REPO controls glial differentiation by cooperating with ETS and BTB transcription factors. Development. 2003; 130: 2419–2428
  • Zhang Z, Curtin K D, Sun Y A, Wyman R J. Nested transcripts of gap junction gene have distinct expression patterns. J Neurobiol 1999; 40: 288–301
  • Zinke I, Schütz C S, Katzenberger J D, Bauer M, Pankratz M J. Nutrient control of gene expression in Drosophila: microarray analysis of starvation and sugar-dependent response. EMBO J. 2002; 21: 6162–6173
  • Zou Y, Stoeckli E, Chen H, Tessier-Lavigne M. Squeezing axons out of the gray matter: A role for slit and semaphorin proteins from midline and ventral spinal cord. Cell. 2000; 102: 363–375

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