REFERENCES
- Abraham S. N., Arock M. Mast cells and basophils in innate immunity. Sem. Immunol. 1998; 10: 373–381, [CSA]
- Abrams J. R., Kelley S. L., Hayes E., Kikuchi T., Brown M. J., Kang S., Lebwohl M. G., Guzzo C. A., Jegasothy B. V., Linsley P. S., Krueger J. G. Blockade of T-lymphocyte costimulation with cytotoxic T-lymphocyte-associated antigen 4-immunoglobulin (CTLA4Ig) reverses the cellular pathology of psoriatic plaques, including the activation of keratinocytes, dendritic cells, and endothelial cells. J. Exp. Med. 2000; 192: 681–694, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Aiba S., Katz S. I. Phenotypic and functional characteristics of in vivo-activated Langerhans cells. J. Immunol. 1990; 145: 2791–2796, [PUBMED], [INFOTRIEVE]
- Aiba S., Manome H., Nakagawa S., Mollah Z. U., Mizuashi M., Ohtani T., Yoshino Y., Tagami H. p38 Mitogen-activated protein kinase and extracellular signal-regulated kinases play distinct roles in the activation of dendritic cells by two representative haptens, NiCl2 and 2,4-dinitrochloro-benzene. J. Invest. Dermatol. 2003; 120: 390–399, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Aiba S., Manome H., Yoshino Y., Tagami H. In vitro treatment of human transforming growth factor-β1-treated monocyte-derived dendritic cells with haptens can induce the phenotypic and functional changes similar to epidermal Langerhans cells in the initiation phase of allergic contact sensitivity reaction. Immunology 2000; 101: 68–75, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Aiba S., Terunuma A., Manome H., Tagami H. Dendritic cells differently respond to haptens and irritants by their production of cytokines and expression of co-stimulatory molecules. Eur. J. Immunol. 1997; 27: 3031–3038, [PUBMED], [INFOTRIEVE], [CSA]
- Akaiwa M., Yu B., Umeshita-Suyama R., Terada N., Suto H., Koga T., Arima K., Matsushita S., Saito H., Ogawa H., Furue M., Hamasaki N., Ohshima K., Izuhara K. Localization of human interleukin-13 receptor in non-haematopoietic cells. Cytokine 2001; 13: 75–84, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Albanesi C., Scarponi C., Cavani A., Federici M., Nasorri F., Girolomoni G. Interleukin-17 is produced by both TH1 and TH2 lymphocytes, and modulates interferon-gamma- and interleukin-4-induced activation of human keratinocytes. J. Invest. Dermatol. 2000; 115: 81–87, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Anonymous. ECVAM News and Views. ATLA 1994; 22: 7–11
- Ansel J., Perry P., Brown J., Damm D., Phan T., Hart C., Luger T., Hefeneider S. Cytokine modulation of keratinocyte cytokines. J. Invest. Dermatol. 1990; 94: 101–107, [CROSSREF]
- Araya A. V., Pavez V., Perez C., Gonzalez F., Columbo A., Aguirre A., Schiattino I., Aguillon J. C. Ex vivo lipopolysaccharide (LPS)-induced TNFα, IL-1β, IL-6 and PGE2 secretion in whole blood from Type 1 diabetes mellitus patients with or without aggressive periodontitis. Eur. Cytokine Network 2003; 14: 128–133, [CSA]
- Ardeshna K. M., Pizzey A. R., Devereux S., Khwaja A. The PI3 kinase, p38 SAP kinase, and NF-κ B signal transduction pathways are involved in the survival and maturation of lipopolysaccharide-stimulated human monocyte-derived dendritic cells. Blood 2000; 96: 1039–1046, [PUBMED], [INFOTRIEVE], [CSA]
- Arock M., Devillier P., Luffau G., Guillosson J., Renoux M. Histamine-releasing activity of endogenous peptides on mast cells derived from different sites and species. Int. Arch. Allergy Appl. Immunol. 1989; 89: 229–235, [PUBMED], [INFOTRIEVE], [CSA]
- Arrighi J. F., Rebsamen M., Rousset F., Kindler V., Hauser C. A critical role for p38 mitogen-activated protein kinase in the maturation of human blood-derived dendritic cells induced by lipopolysaccharide, TNFα, and contact sensitizers. J. Immunol. 2001; 166: 3837–3845, [PUBMED], [INFOTRIEVE]
- Asero R. Intolerance to nonsteroidal anti-inflammatory drugs might precede by years the onset of chronic urticaria. J. Allergy Clin. Immunol. 2003; 111: 1095–1098, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Banchereau J., Steinman R. M. Dendritic cells and the control of immunity. Nature 1998; 392: 245–252, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Barker J. N., Mitra R. S., Griffiths C. E., Dixit V. M., Nickoloff B. J. Keratinocytes as initiators of inflammation. Lancet 1991; 337: 211–214, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Barten M. J., Dhein S., Chang H., Bittner H. B., Tarnok A., Rahmel A., Mohr F. W., Gummert J. F. Assessment of immunosuppressive drug interactions: Inhibition of lymphocyte function in peripheral human blood. J. Immunol. Meth. 2003; 283: 99–114, [CSA], [CROSSREF]
- Bauer B., Baier G. Protein kinase C and AKT/protein kinase B in CD4+ T-lymphocytes: New partners in TCR/CD28 signal integration. Mol. Immunol. 2002; 38: 1087–1099, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Bellou A., Schaub B., Ting L., Finn P. W. Toll receptors modulate allergic responses: Interaction with dendritic cells, T-cells and mast cells. Curr. Opin. Allergy Clin. Immunol. 2003; 3: 487–494, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Bini E. J., Weinshel E. H. Severe exacerbation of asthma: A new side effect of interferon-alpha in patients with asthma and chronic hepatitis C. Mayo Clin. Proc. 1999; 74: 367–370, [PUBMED], [INFOTRIEVE], [CSA]
- Blumberg H., Conklin D., Xu W. F., Grossmann A., Brender T., Carollo S., Eagan M., Foster D., Haldeman B. A., Hammond A., Haugen H., Jelinek L., Kelly J. D., Madden K., Maurer M. F., Parrish-Novak J., Prunkard D., Sexson S., Sprecher C., Waggie K., West J., Whitmore T. E., Yao L., Kuechle M. K., Dale B. A., Chandrasekher Y. A. Interleukin 20: Discovery, receptor identification, and role in epidermal function. Cell 2001; 104: 9–19, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Bohn E., Autenrieth I. B. IL-12 is essential for resistance against Yersinia enterocolitica by triggering IFNγ production in NK cells and CD4+ T-cells. J. Immunol. 1996; 156: 1458–1468, [PUBMED], [INFOTRIEVE]
- Boislève F., Kerdine-Römer S., Rougier-Larzat N., Pallardy M. Nickel and dinitrochlorobenzene induced CCR7 expression on human dendritic cells through different signalling pathways: Role of TNFα and MAPK pathway. J. Invest. Dermatol. 2004; 123: 494–502, [CROSSREF]
- Bolt H. M., Kiesswetter E. Is multiple chemical sensitivity a clinically defined entity?. Toxicol. Lett. 2002; 128: 99–106, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Bondy G. S., Pestka J. J. Dietary exposure to the trichothecene vomitoxin (deoxynivalenol) stimulates terminal differentiation of Peyer's patch B-cells to Ia-secreting plasma cells. Toxicol. Appl. Pharmacol. 1991; 108: 520–530, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Bonish B., Jullien D., Dutronc Y., Huang B. B., Modlin R., Spada F. M., Porcelli S. A., Nickoloff B. J. Overexpression of CD1d by keratinocytes in psoriasis and CD1d-dependent IFNγ production by NK-T cells. J. Immunol. 2000; 165: 4076–4085, [PUBMED], [INFOTRIEVE]
- Borgermann J., Friedrich I., Flohe S., Spillner J., Majetschak M., Kuss O., Sablotzki A., Feldt T., Reidemeister J. C., Schade F. U. Tumor necrosis factor-alpha production in whole blood after cardiopulmonary bypass: Down-regulation caused by circulating cytokine-inhibitory activities. J. Thorac. Cardiovasc. Surg. 2002; 124: 608–617, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Manual of Immunological Methods, P. Brousseau, Y. Payette, H. Tryphonas, B. Blakley, H. Boermans, D. Flip, M. Fournier. CRC Press, New York 1998
- Bugelski P. J., Thiem P. A., Soleveld H. A., Morgan D. G. Effects of sensitization to dinitrochlorobenzene (DNCB) on clinical pathology parameters and mitogen-mediated blastogenesis in cynomolgus monkeys (Macaca fascicularis). Toxicol. Pathol. 1990; 18: 643–650, [PUBMED], [INFOTRIEVE]
- Burchiel S. W., Kerkvliet N. L., Gerberick G. F., Lawrence D. A., Ladics G. S. Assessment of immunotoxicity by multiparameter flow cytometry. Fundam. Appl. Toxicol. 1997; 38: 38–54, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Burns L. A., White K. L., McCay J. A., Fuchs B. A., Stern M., Brown R. D., Musgrove D. L., Holsapple M. P., Luster M. I., Bradley S. G. Immunotoxicity of mono-nitrotoluenes in female B6C3F1 mice: II. Meta-nitrotoluene. Drug. Chem. Toxicol. 1994; 17: 359–399, [PUBMED], [INFOTRIEVE], [CSA]
- Caron G., Delneste Y., Roelandts E., Duez C., Bonnefoy J. Y., Pestel J., Jeannin P. Histamine polarizes human dendritic cells into TH2 cell-promoting effector dendritic cells. J. Immunol. 2001b; 167: 3682–3686, [PUBMED], [INFOTRIEVE]
- Caron G., Delneste Y., Roelandts E., Duez C., Herbault N., Magistrelli G., Bonnefoy J. Y., Pestel J., Jeannin P. Histamine induces CD86 expres-sion and chemokine production by human immature dendritic cells. J. Immunol. 2001a; 166: 6000–6006, [PUBMED], [INFOTRIEVE]
- Caux C., Dezutter-Dambuyant C., Schmitt D., Banchereau J. GM-CSF and TNFα cooperate in the generation of dendritic Langerhans cells. Nature 1992; 360: 258–261, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Caux C., Massacrier C., Vanbervliet B., Dubois B., Van Kooten C., Durand I., Banchereau J. Activation of human dendritic cells through CD40 cross-linking. J. Exp. Med. 1994; 180: 1263–1272, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Cederbrant K., Marcusson-Stahl M., Condevaux F., Descotes J. NK-cell activity in immunotoxicity drug evaluation. Toxicology 2003; 185: 241–250, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Cella M., Salio M., Sakakibara Y., Langen H., Julkunen I., Lanzavecchia A. Maturation, activation, and protection of dendritic cells induced by double-stranded RNA. J. Exp. Med. 1999; 189: 821–829, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Cella M., Sallusto F., Lanzavecchia A. Origin, maturation and antigen presenting function of dendritic cells. Curr. Opin. Immunol. 1997; 9: 10–16, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Companjen A. R., van der Velden V. H., Vooys A., Debets R., Benner R., Prens E. P. Human keratinocytes are major producers of IL-18: Predominant expression of the unprocessed form. Eur. Cytokine Netw. 2000; 11: 383–390, [PUBMED], [INFOTRIEVE], [CSA]
- Condevaux F., Guichard J., Forichon A., Aujoulat M., Descotes J. Compared effects of morphine and nickel chloride on NK cell activity in vitro in rats and monkeys. J. Appl. Toxicol. 2001; 21: 431–434, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Corsini E., Primavera A., Marinovich M., Galli C. L. Selective induction of cell-associated interleukin-1alpha in murine keratinocytes by chemical allergens. Toxicology 1998; 129: 193–200, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Corsini E., Limiroli E., Marinovich M., Cohen C., Roguet R., Galli C. L. Selective induction of interleukin-12 by chemical allergens in reconstituted human epidermis. ATLA 1999; 27: 261–269
- Coutant K. D., de Fraissinette A. B., Cordier A., Ulrich P. Modulation of the activity of human monocyte-derived dendritic cells by chemical haptens, a metal allergen, and a staphylococcal superantigen. Toxicol. Sci. 1999a; 52: 189–198, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Coutant K. D., Ulrich P., Thomas H., Cordier A., Brugerolle de Fraissinette A. Early changes in murine epidermal cell phenotype by contact sensitizers. Toxicol. Sci. 1999b; 48: 74–81, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Crivellato E., Beltrami C. A., Mallardi F., Ribatti D. The mast cell: An active participant or an innocent bystander?. Histol. Histopathol. 2004; 19: 259–270, [PUBMED], [INFOTRIEVE], [CSA]
- Cumberbatch M., Dearman R. J., Antonopoulos C., Groves R. W., Kimber I. Interleukin (IL)-18 induces Langerhans cell migration by a tumour necrosis factor-alpha- and IL-1β -dependent mechanism. Immunology 2001; 102: 323–330, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Cumberbatch M., Dearman R. J., Kimber I. Langerhans cells require signals from both tumour necrosis factor-alpha and interleukin-1β for migration. Immunology 1997; 92: 388–395, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Degwert J. S., Hoppe U., Kligman L. H. In vitro model for contact sensitization: I. Stimulatory capacities of human blood-derived dendritic cells and their phenotypical alterations in the presence of contact sensitizers. Toxicol. In Vitro 1997; 11: 613–618, [CSA], [CROSSREF]
- Demoly P., Bousquet J. Epidemiology of drug allergy. Curr. Opin. Allergy Clin. Immunol. 2001; 1: 305–310, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Derocq J. M., Segui M., Poinot-Chazel C., Minty A., Caput D., Ferrara P., Casellas P. Interleukin-13 stimulates interleukin-6 production by human keratinocytes. Similarity with interleukin-4. FEBS Lett. 1994; 343: 32–36, [PUBMED], [INFOTRIEVE], [CROSSREF]
- De Smedt A. C., Van Den Heuvel R. L., Zwi Berneman N., Schoeters G. E. Modulation of phenotype, cytokine production and stimulatory function of CD34+-derived DC by NiCl2 and SDS. Toxicol. In Vitro 2001; 15: 319–325, [PUBMED], [INFOTRIEVE], [CSA]
- Descotes J. Immunomodulating agents and hepatic drug-metabolizing enzymes. Drug. Metab. Rev. 1985; 16: 175–184, [PUBMED], [INFOTRIEVE]
- Immunotoxicity of Drugs and Chemicals, Principles and Methods in Immunotoxicology, J. Descotes. Elsevier, Amsterdam 2004a; Vol. 1
- Descotes J. Health consequences of immunotoxic effects. Immunotoxicology of Drugs and Chemicals: An Experimental and Clinical Approach, Principles and Methods of Immunotoxicology, J. Descotes. Elsevier, Amsterdam 2004b; Vol. 1: 55–126
- Devouassoux G., Saxon A., Metcalfe D. D., Prussin C., Colomb M. G., Brambilla C., Diaz-Sanchez D. Chemical constituents of diesel exhaust particles induce IL-4 production and histamine release by human basophils. J. Allergy Clin. Immunol. 2002; 109: 847–853, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Dewailly E., Ayotte P., Bruneau S., Gingras S., Belles-Isles M., Roy R. Susceptibility to infections and immune status in Inuit infants exposed to organochlorines. Environ. Health Perspect. 2000; 108: 205–211, [PUBMED], [INFOTRIEVE], [CSA]
- Dieu-Nosjean M. C., Massacrier C., Homey B., Vanbervliet B., Pin J. J., Vicari A., Lebecque S., Dezutter-Dambuyant C., Schmitt D., Zlotnik A., Caux C. Macrophage inflammatory protein 3alpha is expressed at inflamed epithelial surfaces and is the most potent chemokine known in attracting Langerhans cell precursors. J. Exp. Med. 2000; 192: 705–718, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Enk A. H., Katz S. I. Early molecular events in the induction phase of contact sensitivity. Proc. Natl. Acad. Sci. USA 1992; 89: 1398–1402, [PUBMED], [INFOTRIEVE], [CSA]
- Fennrich S., Fischer M., Hartung T., Lexa P., Montag-Lessing T., Sonntag H. G., Weigandt M., Wendel A. Detection of endotoxins and other pyrogens using human whole blood. Dev. Biol. Standards. 1999; 101: 131–139, [CSA]
- Flavell R. A., Dong C., Davis R. J. Signaling and cell death in lymphocytes. Inflamm. Res. 2002; 51: 80–82, [PUBMED], [INFOTRIEVE], [CSA]
- Forster R., Schubel A., Breitfeld D., Kremmer E., Renner-Muller I., Wolf E., Lipp M. CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs. Cell 1999; 99: 23–33, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Fowler C. J., Sandberg M., Tiger G. Effects of water-soluble cigarette smoke extract upon release of β-hexosaminidase from RBL-2H3 basophilic leukaemia cells in response to substance P, compound 48/80, concanavalin A and antigen stimulation. Inflamm. Res. 2003; 52: 461–469, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Geissmann F., Prost C., Monnet J. P., Dy M., Brousse N., Hermine O. Transforming growth factor-beta-1, in the presence of granulocyte/macrophage colony-stimulating factor and interleukin 4, induces differentiation of human peripheral blood monocytes into dendritic Langerhans cells. J. Exp. Med. 1998; 187: 961–966, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Goebeler M., Trautmann A., Voss A., Brocker E. V., Toksoy A., Gillitzer R. Differential and sequential expression of multiple chemokines during elicitation of allergic contact hypersensitivity. Am. J. Pathol. 2001; 158: 431–440, [PUBMED], [INFOTRIEVE]
- Gore E. R., Gower J., Kurali E., Sui J., Bynum J., Ennulat D., Herzyk D. J. Primary antibody response to keyhole limpet hemocyanin in rat as a model for immunotoxicity evaluation. Toxicology 2004; 197: 23–35, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Grabbe S., Schwarz T. Immunoregulatory mechanisms involved in elicitation of allergic contact hypersensitivity. Immunol. Today 1998; 19: 37–44, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Grabbe S., Steinert M., Mahnke K., Schwartz A., Luger T. A., Schwarz T. Dissection of antigenic and irrative effects of epicutaneously applied haptens in mice. Evidence that not the antigenic component but non-specific proinflam-matory effects of haptens determine the concentration-dependent elicitation of allergic contact dermatitis. J. Clin. Invest. 1996; 98: 1158–1164, [PUBMED], [INFOTRIEVE], [CSA]
- Granberg M., Fowler C. J., Jacobsson S. O. Effects of the cannabimimetic fatty acid derivatives 2-arachidonoylglycerol, anandamide, palmitoylethanol-amide and methanandamide upon IgE-dependent antigen-induced β -hexosamin-idase, serotonin and TNFα release from rat RBL-2H3 basophilic leukaemic cells. Naun-Schiedenberg's Arch. Pharmacol. 2001; 364: 66–73, [CSA], [CROSSREF]
- Gunn M. D., Kyuwa S., Tam C., Kakiuchi T., Matsuzawa A., Williams L. T., Nakano H. Mice lacking expression of secondary lymphoid organ chemo-kine have defects in lymphocyte homing and dendritic cell localization. J. Exp. Med. 1999; 189: 451–460, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Haas J., Lipkow T., Mohamadzadeh M., Kolde G., Knop J. Induction of inflammatory cytokines in murine keratinocytes upon in vivo stimulation with contact sensitizers and tolerizing analogues. Exp. Dermatol. 1992; 1: 16–83
- Hacker H., Mischak H., Miethke T. CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation. Embo J. 1998; 17: 6230–6240, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Haig D. M., McMenamin C., Redmond J., Brown D., Young I. G., Cohen S. D., Hapel A. J. Rat IL-3 stimulates the growth of rat mucosal mast cells in culture. Immunology 1988; 65: 205–211, [PUBMED], [INFOTRIEVE]
- Han G. W., Iwatsuki K., Inoue M., Matsui T., Nishibu A., Akiba H., Kaneko F. Interleukin-15 is not a constitutive cytokine in the epidermis, but is inducible in culture or inflammatory conditions. Acta Derm. Venereol. 1999; 79: 37–40, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Hart D. N. Dendritic cells: Unique leukocyte populations that control the primary immune response. Blood 1997; 90: 3245–3287, [PUBMED], [INFOTRIEVE], [CSA]
- Hartung T. Comparison and validation of novel pyrogen tests based on the human fever reaction. ATLA 2002; 30: 49–51, (Suppl. 2)[PUBMED], [INFOTRIEVE]
- Hartung T., Aaberge I., Berthold S., Carlin G., Charton E., Coecke S., Fennrich S., Fischer M., Gommer M., Halder M., Haslov K., Jahnke M., Monatg-Lessing T., Poole S., Schechtman L., Wendel A., Werner-Felmayer G. ECVAM workshop on novel pyrogen tests based on the human fever reaction. ATLA 2001; 29: 99–123, [PUBMED], [INFOTRIEVE]
- Hartung T., Döcke W. D., Gantner F., Krieger G., Sauer A., Stevens P., Volk H. -D., Wendel A. Effect of granulocyte colony-stimulating factor treatment on ex vivo blood cytokine response in human volunteers. Blood 1995; 85: 2482–2489, [PUBMED], [INFOTRIEVE], [CSA]
- Heagy W., Nieman K., Hansen C., Cohen M., Danielson D., West M. A. Lower levels of whole blood LPS-stimulated cytokine release are associated with poorer clinical outcomes in surgical ICU patients. Surg. Infect (Larchmt). 2003; 4: 171–180, [CSA], [CROSSREF]
- Helm R. M. Hypersensitivity reactions: Non-rodent animal models. Investigative Immunotoxicology, H. Tryphonas, M. Fournier, J. E. Blakley, J. E. Smits, P. Brousseau. CRC Press, Boca Raton, FL 2005, Chapter 18
- Henz B. M., Maurer M., Lippert U., Worm M., Babina M. Mast cells as initiators of immunity and host defense. Exp. Dermatol. 2001; 10: 1–10, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Hermann C., von Aulock S., Graf K., Hartung T. A model of human whole blood lymphokine release for in vitro and ex vivo use. J. Immunol. Meth. 2003; 275: 69–79, [CSA], [CROSSREF]
- Hertz-Picciotto I., Dostal M., Dejmek J., Selevan S. G., Wegienka G., Gomez-Caminero A., Sram R. J. Air pollution and distributions of lymphocyte immunophenotypes in cord and maternal blood at delivery. Epidemiology 2002; 13: 172–183, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Hill S., Edwards A. J., Kimber I., Knight S. C. Systemic migration of dendritic cells during contact sensitization. Immunology 1990; 71: 277–281, [PUBMED], [INFOTRIEVE]
- Holladay S. D., Smith B. J. Alterations in murine fetal thymus and liver hematopoietic cell populations following developmental exposure to 7,12-di-methylbenz[a]anthracene. Environ. Res. 1995; 68: 106–113, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Homey B., Dieu-Nosjean M. C., Wiesenborn A., Massacrier C., Pin J. J., Oldham E., Catron D., Buchanan M. E., Muller A., deWaal Malefyt R., Deng G., Orozco R., Ruzicka T., Lehmann P., Lebecque S., Caux C., Zlotnik A. Up-regulation of macrophage inflammatory protein-3 alpha/CCL20 and CC chemokine receptor 6 in psoriasis. J. Immunol. 2000; 164: 6621–6632, [PUBMED], [INFOTRIEVE]
- House D., Chinh N. T., Hien T. T., Parry C. P., Ly N. T., Diep T. S., Wain J., Dunstan S., White N. J., Dougan G., Farrar J. J. Cytokine release by lipopolysaccharide-stimulated whole blood from patients with typhoid fever. J. Infect. Dis. 2002; 186: 240–245, [PUBMED], [INFOTRIEVE], [CROSSREF]
- House R. V., Thomas P. T. In vitro induction of cytotoxic T-lymphocytes. Methods in Immunotoxicology, G. R. Burleson, J. H. Dean, A. E. Munson. Wiley-Liss, New York 1995; Vol. 1: 159–171
- House R. V. An overview of in vitro/ex vivo assays for preclinical evaluation of immunomodulation. Human Exp. Toxicol. 2001a; 19: 246–250, [CSA], [CROSSREF]
- House R. V. Cytokine measurement techniques for assessing hypersensi-tivity. Toxicology 2001b; 158: 51–58, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Janeway C. A., Medzhitov R. Innate immune recognition. Annu. Rev. Immunol. 2002; 20: 197–216, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Jerne N. K., Henry C., Nordin A. A., Fuji H., Koros A. M., Lefkovits I. Plaque-forming cells: Methodology and theory. Transplant. Rev. 1974; 18: 130–191, [PUBMED], [INFOTRIEVE]
- Junghans V., Jung T., Neumann C. Human keratinocytes constitutively express IL-4 receptor molecules and respond to IL-4 with an increase in B7/BB1 expression. Exp. Dermatol. 1996; 5: 316–324, [PUBMED], [INFOTRIEVE], [CSA]
- Kämpfer H., Mühl H., Manderscheid M., Kalina U., Kauschat D., Pfeilschifter J., Frank S. Regulation of interleukin-18 (IL-18) expression in keratinocytes (HaCaT): Implications of early wound healing. Eur. Cytokine Netw. 2000; 11: 626–633, [CSA]
- Katz S. I., Tamaki K., Sachs D. H. Epidermal Langerhans cells are derived from cells originating in bone marrow. Nature 1979; 282: 324–326, [PUBMED], [INFOTRIEVE]
- Kemp S. F., Lockey R. F. Anaphylaxis: A review of causes and mechanisms. J. Allergy Clin. Immunol. 2002; 111: 341–348, [CROSSREF]
- Kim Y. M., Im J. Y., Han S. H., Kang H. S., Choi I. IFNγ up-regulates IL-18 gene expression via IFN consensus sequence-binding protein and activator protein-1 elements in macrophages. J. Immunol. 2000; 165: 3198–3205, [PUBMED], [INFOTRIEVE]
- Kirshenbaum A. S., Goff J. P., Semere T., Foster B., Scott L. M., Metcalfe D. D. Demonstration that human mast cells arise from a progenitor cell population that is CD34(+), c-kit(+), and expresses aminopeptidase N (CD13). Blood 1999; 94: 2333–2342, [PUBMED], [INFOTRIEVE], [CSA]
- Klein N. C., Go C. H., Cunha B. A. Infections associated with steroid use. Infect. Dis. Clin. North Amer. 2001; 15: 423–432, [CSA], [CROSSREF]
- Knippels L. M., Penninks A. H. Assessment of the allergic potential of food protein extracts and proteins on oral application using the brown Norway rat model. Environ. Health Perspect. 2003; 111: 233–238, [PUBMED], [INFOTRIEVE], [CSA]
- Koizumi H., Sato-Matsumura K. C., Nakamura H., Shida K., Kikkawa S., Matsumoto M., Toyoshima K., Seya T. Distribution of IL-18 and IL-18 receptor in human skin: Various forms of IL-18 are produced in keratinocytes. Arch. Dermatol. Res. 2001; 293: 325–333, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Komine M., Rao L. S., Freedberg I. M., Simon M., Milisavljevic V., Blumenberg M. Interleukin-1 induces transcription of keratin K6 in human epidermal keratinocytes. J. Invest. Dermatol. 2001; 116: 330–338, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Kremer L., Dupre L., Wolowczuk I., Locht C. In vivo immunomodulation following intradermal injection with DNA encoding IL-18. J. Immunol. 1999; 163: 3226–3231, [PUBMED], [INFOTRIEVE]
- Kripke M. L., Munn C. G., Jeevan A., Tang J. M., Bucana C. Evidence that cutaneous antigen-presenting cells migrate to regional lymph nodes during contact sensitization. J. Immunol. 1990; 145: 2833–2838, [PUBMED], [INFOTRIEVE]
- Langezaal I., Hoffmann S., Hartung T., Coecke S. Evaluation and pre-validation of an immunotoxicity test based on human whole-blood cytokine release. ATLA 2002; 30: 581–595, [PUBMED], [INFOTRIEVE]
- Lebrec H., Roger R., Blot C., Burleson G. R., Bohuon C., Pallardy M. Immunotoxicological investigation using pharmaceutical drugs. In vitro evaluation of immune effects using rodent or human immune cells. Toxicology 1995; 96: 147–156, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Leonardi G. S., Houthuijs D., Steerenberg P. A., Fletcher T., Armstrong B., Antova T., Lochman I., Lochmanova A., Rudnai P., Erdei E., Musial J., Jazwiec-Kanyion B., Niciu E. M., Durbaca S., Fabianova E., Koppova K., Lebret E., Brunekreef B., van Loveren H. Immune biomarkers in relation to exposure to particulate matter: A cross-sectional survey in 17 cities of Central Europe. Inhal. Toxicol. 2000; 12: 1–14, (Suppl. 4)[PUBMED], [INFOTRIEVE], [CSA]
- Levy S. M., Herberman R. B., Lee J., Whiteside T., Beadle M., Heiden L., Simons A. Persistently low natural killer cell activity, age, and environmental stress as predictors of infectious morbidity. Nat. Immun. Cell. Growth Regul. 1991; 10: 289–307, [PUBMED], [INFOTRIEVE]
- Lisby S., Muller K. M., Jongeneel C. V., Saurat J. H., Hauser C. Nickel and skin irritants up-regulate tumor necrosis factor-alpha mRNA in keratinocytes by different but potentially synergistic mechanisms. Int. Immunol. 1995; 7: 343–352, [PUBMED], [INFOTRIEVE]
- Love K. S., Lakshmanan R. R., Butterfield J. H., Fox C. C. IFNγ -stimulated enhancement of MHC Class II antigen expression by the human mast cell line HMC-1. Cell. Immunol. 1996; 170: 85–90, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Lü Y. C. Clinical findings and immunological abnormalities in Yu-Cheng patients. Environ. Health Perspect. 1985; 59: 17–29
- Luster M. I., Portier C., Pait D. G., Rosenthal G. J., Germolec D. R., Corsini E., Blaylock B. L., Pollock P., Kouchi Y., Craig W., White K. L., Munson A. E., Comment C. E. Risk assessment in immunotoxicology II. Relationships between immune and host resistance tests. Fundam. Appl. Toxicol. 1993; 21: 71–82, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Luster M. I., Portier C., Pait D. G., White K. L., Gennings C., Munson A. E., Rosenthal G. J. Risk assessment in immunotoxicology I. Sensitivity and predictability of immune tests. Fundam. Appl. Toxicol. 1992; 18: 200–210, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- MacGlashan D. Histamine: A mediator of inflammation. J. Allergy Clin. Immunol. 2003; 112: 53–59, [CROSSREF]
- Marcusson-Stahl M., Cederbrant K. A flow-cytometric NK-cytotoxicity assay adapted for use in rat repeated dose toxicity studies. Toxicology 2003; 193: 269–279, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Masten S. A., Shiverick K. T. The Ah receptor recognizes DNA binding sites for the B-cell transcription factor, BSAP: A possible mechanism for dioxin-mediated alteration of CD19 gene expression in human B-lymphocytes. Biochem. Biophys. Res. Commun. 1995; 212: 27–34, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- McKenzie R. C., Sauder D. N. The role of keratinocyte cytokines in inflammation and immunity. J. Invest. Dermatol. 1990; 95: 105S–107S, [PUBMED], [INFOTRIEVE], [CROSSREF]
- McLachlan J. B., Hart J. P., Pizzo S. V., Shelburne C. P., Staats H. F., Gunn M. D., Abraham S. N. Mast cell-derived tumor necrosis factor induces hyper-trophy of draining lymph nodes during infection. Nat. Immunol. 2003; 4: 1199–1205, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Mee J. B., Alam Y., Groves R. W. Human keratinocytes constitutively produce but do not process interleukin-18. Br. J. Dermatol. 2000; 143: 330–336, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Miossec P. Cytokine-induced autoimmune disorders. Drug Safety 1997; 17: 93–104, [PUBMED], [INFOTRIEVE], [CSA]
- Mohamadzadeh M., Muller M., Hultsch T., Enk A., Saloga J., Knop J. Enhanced expression of IL-8 in normal human keratinocytes and human keratinocyte cell line HaCaT in vitro after stimulation with contact sensitizers, tolerogens and irritants. Exp. Dermatol. 1994; 3: 298–303, [PUBMED], [INFOTRIEVE], [CSA]
- Moore K. W., de Waal Malefyt R., Coffman R. L., O'Garra A. Interleukin-10 and the interleukin-10 receptor. Annu. Rev. Immunol. 2001; 19: 683–765, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Muller G., Saloga J., Germann T., Bellinghausen I., Mohamadzadeh M., Knop J., Enk A. H. Identification and induction of human keratinocyte-derived IL-12. J. Clin. Invest. 1994; 94: 1799–1805, [PUBMED], [INFOTRIEVE], [CSA]
- Müschen A., Mirmohammadsadegh A., Jarzebska-Deussen B., Abts H. F., Ruzicka T., Michel G. Differential IL-10 receptor gene expression in acute versus chronic atopic eczema. Modulation by immunosuppressive drugs and cytokines in normal cultured keratinocytes. Inflamm. Res. 1999; 48: 539–543, [CSA], [CROSSREF]
- Naik A. M., Canno G., Burbach G. J., Singh S. R., Swerlick R. A., Wilcox J. N., Ansel J. C., Caugham S. W. Human keratinocytes constitutively express IL-18 and secrete biologically active IL-18 after treatment with proinflam-matory mediators and dinitrochlorobenzene. J. Invest. Dermatol. 1999; 113: 766–772, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Nakanishi Y., Shigematsu N., Kurita Y., Matsuba K., Kanegae H., Ishimaru S., Kawazoe Y. Respiratory involvement and immune status in Yusho patients. Environ. Health Perspect. 1985; 59: 31–36, [PUBMED], [INFOTRIEVE]
- Nakayama T., Fujisawa R., Yamada H., Horikawa T., Kawasaki H., Hieshima K., Izawa D., Fujiie S., Tezuka T., Yoshie O. Inducible expression of a CC chemokine liver- and activation-regulated chemokine (LARC)/macrophage inflammatory protein (MIP)-3α /CCL20 by epidermal keratinocytes and its role in atopic dermatitis. Int. Immunol. 2001; 13: 95–103, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Ohta Y., Hamada Y., Katsuoka K. Expression of IL-18 in psoriasis. Arch. Dermatol. Res. 2001; 293: 334–342, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Pasqualetti D., Ghirardini A., Cafolla A., Biffoni M., Coluzzi S., Vaglio S., Girelli G. Lymphocyte T subsets and natural killer cells in Italian and Philippino blood donors. Vox Sang. 2003; 84: 68–72, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Pastore S., Shivji G. M., Kondo S., Kono T., McKenzie R. C., Segal L., Somers D., Sauder D. N. Effects of contact sensitizers neomycin sulfate, benzo-caine and 2,4-dinitrobenzene 1-sulfonate, sodium salt on viability, membrane integrity and IL-1α mRNA expression of cultured normal human keratinocytes. Food Chem. Toxicol. 1995; 33: 57–68, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Penn I. De novo cancers in organ allograft recipients. Curr. Opin. Organ Transplant 1995; 3: 188–196
- Perkins S. L. Examination of the blood and bone marrow. Wintrobe's Clinical Hematology, 10th Edition, G. R. Lee, J. Foersten, J. Lukens, F. Panaskevas, J. Greer, G. Rodgers, M. Wintrobe. Williams & Wilkins, Baltimore, MD 1999; Vol. 1: 9–35
- Pessina A., Albella B., Bueren J., Brantom P., Casati S., Gribaldo L., Croera C., Gagliardi G., Foti P., Parchment R., Parent-Massin D., Sibiril Y., van den Heuvel R. Prevalidation of a model for predicting acute neutropenia by colony forming unit granulocyte/macrophage (CFU-GM) assay. Toxicol. in Vitro 2001; 15: 729–740, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Petsonk E. L. Work-related asthma and implications for the general public. Environ. Health Perspect. 2002; 110: 569–572, (Suppl. 4)[PUBMED], [INFOTRIEVE], [CSA]
- Pieters R., Ezendam J., Bleumink R., Bol M., Nierkens S. Predictive testing for autoimmunity. Toxicol. Lett. 2002; 127: 83–91, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Prussin C., Metcalfe D. D. IgE, mast cells, basophils, and eosinophils. J. Allergy Clin. Immunol. 2003; 111: 486–494, [CSA], [CROSSREF]
- Pulido O., Caldwell D., Murphy M., Gill S. Practical considerations for the toxicologic pathology assessment of the immune system in rodents and non-human primates. Investigative Immunotoxicology, H. Tryphonas, M. Fournier, J. E. Blakley, J. E. Smits, P. Brousseau. CRC Press, Boca Raton, FL 2005, Chapter 15
- Puxeddu I., Piliponsky A. M., Bachelet I., Levi-Schaffer F. Mast cells in allergy and beyond. Int. J. Biochem. Cell. Biol. 2003; 35: 1601–1607, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Reich K., Garbe C., Blaschke V., Maurer C., Middel P., Westphal G., Lippert U., Neumann C. Response of psoriasis to interleukin-10 is associated with suppression of cutaneous type 1 inflammation, downregulation of the epidermal interleukin-8/CXCR2 pathway and normalization of keratinocyte maturation. J. Invest. Dermatol. 2001; 116: 319–329, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Renton K. W. Alteration of drug biotransformation and elimination during infection and inflammation. Pharmacol. Ther. 2001; 92: 147–163, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Rescigno M., Martino M., Sutherland C. L., Gold M. R., Ricciardi-Castagnoli P. Dendritic cell survival and maturation are regulated by different signaling pathways. J. Exp. Med. 1998; 188: 2175–2180, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Rhile M. J., Nagarkatti M., Nagarkatti P. S. Role of Fas apoptosis and MHC genes in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced immunotoxicity of T-cells. Toxicology 1996; 110: 153–167, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Rietschel R. L., Mathias C. G., Fowler J. F., Pratt M., Taylor J. S., Sherertz E. F., Marks J. G., Belsito D. V., Storrs F. J., Maibach H. I., Fransway A. F., Deleo V. A. North American Contact Dermatitis Group. Relationship of occupation to contact dermatitis: Evaluation in patients tested from 1998 to 2000. Am. J. Contact Derm. 2002; 13: 170–176, [CSA], [CROSSREF]
- Robbie-Ryan M., Brown M. The role of mast cells in allergy and autoimmunity. Curr. Opin. Immunol. 2002; 14: 728–733, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Robinson S. N., Shah R., Wong B. A., Wong V. A., Farris G. M. Immunotoxicological effects of benzene inhalation in male Sprague–Dawley rats. Toxicology 1997; 119: 227–237, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Ross P., De Swart R., Addison R., van Loveren H., Vos J., Osterhaus A. Contaminant-induced immunotoxicity in harbour seals: Wildlife at risk?. Toxicology 1996; 112: 157–169, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Rottman J. B., Smith T. L., Ganley K. G., Kikuchi T., Krueger J. G. Potential role of the chemokine receptors CXCR3, CCR4, and the integrin αE β 7 in the pathogenesis of psoriasis vulgaris. Lab. Invest. 2001; 81: 335–347, [PUBMED], [INFOTRIEVE], [CSA]
- Rougier N., Redziniak G., Mougin D., Schmitt D., Vincent C. In vitro evaluation of the sensitization potential of weak contact allergens using Langerhans-like dendritic cells and autologous T-cells. Toxicology 2000; 145: 73–82, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Saeki H., Moore A. M., Brown M. J., Hwang S. T. Cutting edge: Secondary lymphoid-tissue chemokine (SLC) and CC chemokine receptor 7 (CCR7) participate in the emigration pathway of mature dendritic cells from the skin to regional lymph nodes. J. Immunol. 1999; 162: 2472–2475, [PUBMED], [INFOTRIEVE]
- Schindler S., Hartung T., the Human(e) Pyrogen Test Study Group. Comparison and validation of novel pyrogen tests based on the human fever reaction. Dev. Biol. Stand. 2002; 111: 181–186
- Schulman K. L., Thompson J. A., Benyunes M. C., Winter T. C., Fefer A. Adverse reactions to intravenous contrast media in patients with interleukin-2. J. Immunother. 1993; 13: 208–212
- Sell S. Immunology, Immunopathology and Immunity, 4th Edition. Appleton & Lange, Norwalk, CT 1987
- Shenton J. M., Chen J., Uetrecht J. P. Animal models of idiosyncratic drug reactions. Chem.-Biol. Interact. 2004; 150: 53–70, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Shipp K., Woodward B. D. A simple exsanguination method that minimizes acute pre-anesthesia stress in the mouse: Evidence based on serum corticosterone concentrations. Contemp. Topics Lab. Anim. Sci. 1998; 37: 73–77
- Sia I. G., Paya C. V. Infectious complications following renal trans-plantation. Surg. Clin. North Amer. 1998; 78: 95–112, [CROSSREF]
- Siddiqui A. A., Miner P. B. The role of mast cells in common gastro-intestinal diseases. Curr. Allergy Asthma Rep. 2004; 4: 47–54, [PUBMED], [INFOTRIEVE], [CSA]
- Sleijffers A., Garssen J., van Loveren H. Ultraviolet radiation, resistance to infectious diseases, and vaccination responses. Methods 2002; 28: 111–121, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Steinman R. M., Cohn Z. A. Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution. J. Exp. Med. 1973; 137: 1142–1162, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Stewart C. C., Cookfair D. L., Hovey K. M., Wende K. E., Bell D. S., Warner C. L. Predictive immunophenotypes: Disease-related profile in chronic fatigue syndrome. Cytometry 2003; 53: 26–33, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Strait R. T., Morris S. C., Yang M., Qu X. W., Finkelman F. D. Pathways of anaphylaxis in the mouse. J. Allergy Clin. Immunol. 2002; 109: 658–668, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Sundwall A., Andersson B., Balls M., Dean J., Descotes J., Hammarstrom S., Hultman P., Kimber I., Lorentz M., Luster M., Moldeus P., Odland L., Sjogren H. O., Stejkal V., Walum E., Veronesi B., White K., Vos J. Workshop: Immunotoxicology and in vitro possibilities. Toxicol. In Vitro 1994; 8: 1067–1074
- Termorshuizen F., Garssen J., Norval M., Koulu L., Laihia J., Leino L., Jansen C. T., De Gruijl F., Gibbs N. K., De Simone C., van Loveren H. A review of studies on the effects of ultraviolet irradiation on the resistance to infections: Evidence from rodent infection models and verification by experimental and observational human studies. Int. Immunopharmacol. 2002; 2: 263–275, [PUBMED], [INFOTRIEVE]
- Theoharides T. C., Cochrane D. E. Critical role of mast cells in inflammatory diseases and the effect of acute stress. J. Neuroimmunol. 2004; 146: 1–12, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Trinchieri G. Biology of natural killer cells. Adv. Immunol. 1989; 47: 187–376, [PUBMED], [INFOTRIEVE]
- Tryphonas H. The primate immune system (non-human) and environmental contaminants. Encyclopedia of Immunotoxicology, H. W. Vohr. Springer Press, Heidelberg 2005; 532–536
- Tryphonas H., Feeley M. Polychlorinated biphenyl-induced immuno-modulation and human health effects, in PCBs. Recent Advances in Environmental Toxicology and Health Effects, L. W. Robertson, L. G. Hansen. The University Press of Kentucky. 2001; 194–209
- Tryphonas H., Lacroix F., Hayward S., Izaguirre C., Parenteau M., Fournier J. Cell surface marker evaluation of infant Macaca monkey leukocytes in peripheral whole blood using simultaneous dual-color immunophenotypic analysis. J. Med. Primatol. 1996; 25: 89–105, [PUBMED], [INFOTRIEVE], [CSA]
- Tsuji K., Zsebo K. M., Ogawa M. Murine mast cell colony formation supported by IL-3, IL-4, and recombinant rat stem cell factor, ligand for c-kit. J. Cell. Physiol. 1991; 148: 362–369, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Tuschl H., Kovac R., Weber E. The expression of surface markers on dendritic cells as indicators for the sensitizing potential of chemicals. Toxicol. In Vitro 2000; 14: 541–549, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Ullrich S. E. Mechanism involved in the systemic suppression of antigen-presenting cell function by UV irradiation. Keratinocyte-derived IL-10 modulates antigen-presenting cell function of splenic adherent cells. J. Immunol. 1994; 152: 3410–3416, [PUBMED], [INFOTRIEVE]
- Underhill D. M., Ozinsky A. Toll-like receptors: Key mediators of microbe detection. Curr. Opin. Immunol. 2002; 14: 103–110, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- van Loveren H. Host resistance models. Human. Exp. Toxicol. 1995; 14: 137–140, [CSA]
- van Loveren H., Vos J. G. Immunotoxicological considerations: A practical approach to immunotoxicity testing in the rat. Advances in Applied Toxicology, A. D. Dayan, A. J. Puine. Taylor and Francis, London 1989; 143–164
- van Loveren H., Vos J. G. Evaluation of OECD Guideline No. 407 for Assessment of Toxicity of Chemicals with Respect to Potential Adverse Effects to the Immune System, National Institute of Public Health and Environmental Protection, Bilthoventhe Netherlands 1992
- Van Och F. M., Van Loveren H., Van Wolfswinkel J. C., Machielsen A. J., Vandebriel R. J. Assessment of potency of allergenic activity of low molecular weight compounds based on IL-1 alpha and IL-18 production by a murine and human keratinocyte cell line. Toxicology 2005; 210: 95–109, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Vestergaard C., Bang K., Gesser B., Yoneyama H., Matsushima K., Larsen C. G. A TH2 chemokine, TARC, produced by keratinocytes may recruit CLA+CCR4+ lymphocytes into lesional atopic dermatitis skin. J. Invest. Dermatol. 2000; 115: 640–646, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Vial T., Choquet-Kastylevsky G., Descotes J. Adverse effects of immunotherapeutics involving the immune system. Toxicology 2002; 174: 3–11, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Vial T., Descotes J. Immune-mediated side effects of cytokines in humans. Toxicology 1995; 105: 31–57, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Vial T., Descotes J. Immunosuppressive drugs and cancer. Toxicology 2003; 185: 229–240, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- von Aulock S., Hermann C., Hartung T. Determination of the eicosanoid response to inflammatory stimuli in whole blood and its pharmacological modulation ex vivo. J. Immunol. Meth. 2003; 188: 938–943
- Vos J. G. Immuntoxicity assesment screening and function studies. Arch. Toxicol. 1980; 4: 95–108
- Vos J. G., van Loveren H. Development of immunotoxicology methods in the rat and applications to the study of environmental pollutants. Toxicol. In Vitro. 1994; 8: 951–956, [CROSSREF]
- Wagner L. A., Brown T., Gil S., Frank I., Carter W., Tamura R., Wayner E. A. The keratinocyte-derived cytokine IL-7 increases adhesion of the epidermal T-cell subset to the skin basement membrane protein laminin-5. Eur. J. Immunol. 1999; 29: 2530–2538, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Wajant H., Pfizenmaier K., Scheurich P. Tumor necrosis factor signaling. Cell Death Differ. 2003; 10: 45–65, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Wakem P., Burns R. P., Jr., Ramirez F., Zlotnick D., Ferbel B., Haidaris C. G., Gaspari A. A. Allergens and irritants transcriptionally upregulate CD80 gene expression in human keratinocytes. J. Invest. Dermatol. 2000; 114: 1085–1092, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Wang M., Tan Z., Zhang R., Kotenko S. V., Liang P. Interleukin 24 (MDA-7/MOB-5) signals through two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2. J. Biol. Chem. 2002; 277: 7341–7347, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Weigt H., Muhlradt P. F., Larbig M., Krug N., Braun A. The toll-loke receptor-2/6 agonist macrophage-activating lipopeptide-2 cooperates with IFNγ to reverse the TH2 skew in an in vitro allergy model. J. Immunol. 2004; 172: 6080–6086, [PUBMED], [INFOTRIEVE]
- Weisglas-Kuperus N., Vreugdenhil H. J., Mulder P. G. Immunological effects of environmental exposure to polychlorinated biphenyls and dioxins in Dutch school children. Toxicol. Lett. 2004; 149: 281–315, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Wery S., Letourneur M., Bertoglio J., Pierre J. Interleukin-4 induces activation of mitogen-activated protein kinase and phosphorylation of shc in human keratinocytes. J. Biol. Chem. 1996; 271: 8529–8532, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Whiteside T. L., Herberman R. B. The role of natural killer cells in human disease. Clin. Immunol. Immunopathol. 1989; 53: 1–23, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Wilmer J. L., Burleson F. G., Kayama F., Kanno J., Luster M. I. Cytokine induction in human epidermal keratinocytes exposed to contact irritants and its relation to chemical-induced inflammation in mouse skin. J. Invest. Dermatol. 1994; 102: 915–922, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Wilson L. D. Skin cancers after organ transplantation. N. Engl. J. Med. 2003; 349: 612–614, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Wu Z., Turner D. R., Oliveira D. B. IL-4 gene expression up-regulated by mercury in rat mast cells: A role of oxidant stress in IL-4 transcription. Int. Immunol. 2001; 13: 297–304, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Wundelich J. R., Canty T. G. Cell-mediated immunity induced in vitro. Nature 1970; 228: 62–67
- Yamanaka K., Tanaka M., Tsutsui H., Kupper T. S., Asahi K., Okamura H., Nakanishi K., Suzuki M., Kayagaki N., Black R. A., Miller D. K., Nakashima K., Shimizu M., Mizutani H. Skin-specific caspase-1-transgenic mice show cutaneous apoptosis and pre-endotoxin shock condition with a high serum level of IL-18. J. Immunol. 2000; 165: 997–1003, [PUBMED], [INFOTRIEVE]
- Yanagihara S., Komura E., Nagafune J., Watarai H., Yamaguchi Y. EBI1/CCR7 is a new member of dendritic cell chemokine receptor that is up-regulated upon maturation. J. Immunol. 1998; 161: 3096–3102, [PUBMED], [INFOTRIEVE]
- Yawalkar N., Egli F., Brand C. U., Pichler W. J., Braathen L. R. Antigen-presenting cells and keratinocytes express IL-12 in allergic contact dermatitis. Contact Dermatitis 2000; 42: 18–22, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Zepter K., Haffner A., Soohoo L. F., DeLuca D., Tang H. P., Fisher P., Chavinson J., Elmets C. A. Induction of biologically-active IL-1β -converting enzyme and mature IL-1β in human keratinocytes by inflammatory and immunologic stimuli. J. Immunol. 1997; 159: 6203–6208, [PUBMED], [INFOTRIEVE]
- Zuberbier T. Pseudoallergy or nonallergic hypersensitivity. Allergy 1999; 54: 397–398, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]