Trends in dextromethorphan cough and cold products: 2000–2015 National Poison Data System intentional abuse exposure calls

References

• U.S. Food and Drug Administration. Klein M, Overview of the September 14, 2010, DSaRM Advisory Committee Meeting to Discuss the Drug Enforcement Administration (DEA) Request for an Abuse Potential Evaluation and Scheduling Recommendation for Dextromethorphan (DXM); [cited 2010 August 23]. Available from: https://www.fda.gov/downloads/advisorycommittees/drugs/ucm224446.pdf
   Google Scholar
• Drug Enforcement Administration, Office of Diversion Control. Drug and Chemical Evaluation section. Dextromethorphan (Street Names: DXM, CCC, Triple C, Skittles, Robo, Poor Man’s PCP). March, 2014. Available from: http://www.deadiversion.usdoj.gov/drug_chem_info/dextro_m.pdf.
   Google Scholar
• Reissig CJ, Carter LP, Johnson MW, et al. High doses of dextromethorphan, an NMDA antagonist, produce effects similar to classic hallucinogens. Psychopharmacology. 2012;223:1–15.
   PubMed Web of Science ®Google Scholar
• McCarthy JP. Some less familiar drugs of abuse. Med J Aust. 1971;2:1078–1081.
   PubMedGoogle Scholar
• Darboe MN, Keenan GR Jr, Richards TK. The abuse of dextromethorphan-based cough syrup: a pilot study of the community of Waynesboro, Pennsylvania. Adolescence. 1996;31:633–644.
   PubMedGoogle Scholar
• Banerji S, Anderson IB. Abuse of coricidin HBP cough & cold tablets: episodes recorded by a poison center. Am J Health Syst Pharm. 2001;58:1811–1814.
   PubMed Web of Science ®Google Scholar
• G-Baker SD, Borys DJ. A possible trend suggesting increased abuse of coricidin exposures reported to the Texas poison network: comparing 1998 to 1999. Vet Hum Toxicol. 2002;44:169–171.
   PubMedGoogle Scholar
• Bryner JK, Wang UK, Hui JW, et al. Dextromethorphan abuse in adolescence: an increasing trend: 1999–2004. Arch Pediatr Adolesc Med. 2006;160:1217–1222.
   PubMed Web of Science ®Google Scholar
• Schwartz RH. Adolescent abuse of dextromethorphan. Clin Pediatr. 2005;44:565–568.
   PubMed Web of Science ®Google Scholar
• Logan BK, Goldfogel G, Hamilton R, et al. Five deaths resulting from abuse of dextromethorphan sold over the internet. J Anal Toxicol. 2009;33:99–103.
   PubMed Web of Science ®Google Scholar
• Desai S, Aldea D, Daneels E, et al. Chronic addiction to dextromethorphan cough syrup: a case report. J Am Board Fam Med. 2006;19:320–323.
   PubMed Web of Science ®Google Scholar
• Wilson MD, Ferguson RW, Mazer ME, et al. Monitoring trends in dextromethorphan abuse using the National Poison Data System: 2000–2010. Clin Toxicol. 2011;49:409–415.
   PubMed Web of Science ®Google Scholar
• Consumer Healthcare Products Association. Dextromethorphan: preventing Teen Cough Medicine Abuse. Washington (DC): Consumer Healthcare Products Association 2017. Available from: http://www.chpa.org/Dex.aspx
   Google Scholar
• Logan BK, Yeakel JK, Goldfogel G, et al. Dextromethorphan abuse leading to assault, suicide, or homicide. J Forensic Sci. 2012;57:1388–1394.
   PubMed Web of Science ®Google Scholar
• Roy AK, III, Hsieh C, Crapanzano K. Dextromethorphan addiction mediated through the NMDA system: common pathways with alcohol? J Addict Med. 2015;9:499–501.
   PubMed Web of Science ®Google Scholar
• Small E, Sandefur BJ. Acute renal failure after ingestion of guaifenesin and dextromethorphan. J Emerg Med. 2014;47:26–29.
   PubMed Web of Science ®Google Scholar
• Miller SC. Dextromethorphan psychosis, dependence, and physical withdraw. Addict Biol. 2005;10:325–327.
   PubMed Web of Science ®Google Scholar
• Zajac M, Andrzeiczyk A, Kuich A, et al. Recreational usage of dextromethorphan–analysis based on internet users experiences. Prezegl Lek. 2013;70:525–527.
   PubMedGoogle Scholar
• Mowry JB, Spyker DA, Brooks DE, et al. 2015 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 33rd Annual Report. Clin Toxicol. 2016;54:924–1109.
   PubMed Web of Science ®Google Scholar
• American Association of Poison Control Centers. National Poison Data System (NPDS) Data Dictionary. Version 2016.07.11. July 11, 2016.
   Google Scholar
• National Institute on Drug Abuse. Sex and Gender Difference in Substance Abuse. Advancing Addiction Science; [cited Sep 2016]. Available from: https://www.drugabuse.gov/publications/research-reports/substance-use-in-women/sex-gender-differences-in-substance-use
   Google Scholar
• CDC WONDER. Bridged-Race Population Estimates 1990–2015 Request. 2017 [cited 2017 Nov 14]. Available from: https://wonder.cdc.gov/Bridged-Race-v2015.html
   Google Scholar
• National Poison Data System. American Association of Poison Control Centers Annual Reports. 2017 [cited 2017 Nov 14]. Available from: http://www.aapcc.org/annual-reports/.
   Google Scholar
• Partnership for Drug-Free Kids. Over-the-counter Drug Abuse More Common in Boys: Study; [cited 2012 November 2]. Available from: https://www.sciencedaily.com/releases/2012/10/121029154259.htm
   Google Scholar
• SAMHSA, Center for Behavioral Health Statistics and Quality, National Survey on Drug Use and Health, 2006–2013. 2017 [cited 2017 Nov 14]. Available from: http://www.samhsa.gov/data/sites/default/files/NSDUH-DetTabs2013.pdf
   Google Scholar
• Miech RA, Johnson LD, O’Malley PM, et al. Monitoring the future national survey results on drug use 1975–2015: volume i, secondary school students. Ann Arbor (MI): Institute for Social Research, The University of Michigan; 2016.
   Google Scholar
• The Partnership Attitude Tracking Study Teens and Parents 2013. 2017 [cited 2017 Nov 14]. Available from: https://drugfree.org/wp-content/uploads/2014/07/PATS-2013-FULL-REPORT.pdf
   Google Scholar
• Texas School Survey of Drug and Alcohol Use. 2017 [cited 2017 Nov 14]. Available from: http://www.texasschoolsurvey.org/, http://www.texasschoolsurvey.org/Documents/Reports/State/14State712.pdf, http://www.texasschoolsurvey.org/Documents/Reports/State/12State712.pdf, http://www.texasschoolsurvey.org/Documents/Reports/State/10State712.pdf, http://www.texasschoolsurvey.org/Documents/Reports/State/08State712.pdf
   Google Scholar
• Vries L. Cough Medicien Abuse By Kids. CBS News. 2017 [cited 2003 December 29]. Available from: http://www.cbsnews.com/news/cough-medicine-abuse-by-kids/
   Google Scholar
• Stossel J. Teens Using Cold Medicine to Get High. abc NEWS. 2017 [cited 2004 January 9]. Available from: http://abcnews.go.com/2020/story?id=124334
   Google Scholar
• U.S. Food and Drug Administration. Legal Requirements for the Sale and Purchase of Drug Products Containing Pseudoephedrine, Ephedrine, and Phenylpropanolamine; [cited 13 September 2016]. Available from: http://www.fda.gov/Drugs/DrugSafety/InformationbyDrugClass/ucm072423.htm
   Google Scholar
• Soslow AR, Woolf AD. Reliability of data sources for poisoning deaths in Massachusetts. Am J Emerg Med. 1992;10:124–127.
   PubMed Web of Science ®Google Scholar
• SAMHSA, Center for Behavioral Health Statistics and Quality, NSDUH, 2014 and 2015. National Survey on Drug Use and Health National Maps of Prevalence Estimates, by State. 2017 [cited 2017 Nov 14]. Available from: http://samhda.s3-us-gov-west-1.amazonaws.com/s3fs-public/field-uploads/2k15StateFiles/NSDUHsaeMaps2015.htm
   Google Scholar