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Clinical Toxicology Volume 59, 2021 - Issue 2
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Clinical Research

Single versus continued dosing of fomepizole during hemodialysis in ethylene glycol toxicity

Alexander M. Sidlaka Division of Medical Toxicology, Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-2181-8250
ORCID Icon,
Ryan T. Marinob Division of Medical Toxicology, Department of Emergency Medicine, University Hospitals, Cleveland, OH, USAORCID Iconhttps://orcid.org/0000-0001-7005-0474
ORCID Icon,
James P. Van Meerbekec Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
&
Anthony F. Pizona Division of Medical Toxicology, Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Pages 106-110 | Received 30 Jan 2020, Accepted 08 May 2020, Published online: 26 May 2020

References

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  • Brent J, McMartin K, Phillips S, et al. Fomepizole for the treatment of ethylene glycol poisoning. Methylpyrazole for Toxic Alcohols Study Group. N Engl J Med. 1999;340(11):832–838.
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  • Sivilotti MLA, Burns MJ, McMartin KE, et al. Toxicokinetics of ethylene glycol during fomepizole therapy: implications for management. Ann Emerg Med. 2000;36(2):114–125.
  • Faessel H, Houze P, Baud FJ, et al. 4-methylpyrazole monitoring during haemodialysis of ethylene glycol intoxicated patients. Eur J Clin Pharmacol. 1995;49(3):211–213.
  • Hovda KE, Julsrud J, Ovrebo S, et al. Studies on ethylene glycol poisoning: one patient – 154 admissions. Clin Toxicol (Phila). 2011;49(6):478–484.
  • Moreau CL, Kerns W, Tomaszewski CA, et al. Glycolate kinetics and hemodialysis clearance in ethylene glycol poisoning. META Study Group. J Toxicol Clin Toxicol. 1998;36(7):659–666.
  • Porter WH, Rutter PW, Bush BA, et al. Ethylene glycol toxicity: the role of serum glycolic acid in hemodialysis. J Toxicol Clin Toxicol. 2001;39(6):607–615.

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