References
- Watson WA, Litovitz TL, Rodgers GC, Klein-Schwartz W, Reid N, Youniss J, Flanagan A, Wruk KM. 2004 annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System. Am J Emerg Med 2005; 23: 589–666
- 2. Toxic Exposure Surveillance System (TESS). American Association of Poison Control Centers 2000–2005.
- Miller TR, Lestina DC. Costs of poisoning in the United States and savings from poison control centers: a benefit-cost analysis. Ann Emerg Med 1997; 29: 239–245
- Poisindex system, RK Klasco. Thomson Micromedex, Greenwood Village, CO 2004, edition expires March
- Mosby's Drug Consult. Elsevier, Philadelphia 2005, 2005.
- Stork CM. Serotonin reuptake inhibitors and atypical antidepressants. Goldfrank's Toxicologic Emergencies7th, LR Goldfrank, NE Flomenbaum, NA Lewin, MA Howland, RS Hoffman, LS Nelson. McGraw-Hill, New York 2002; 865–874
- Whyte IM, Dawson AH, Buckley NA. Relative toxicity of venlafaxine and selective serotonin reuptake inhibitors in overdose compared to tricyclic antidepressants. QJM 2003; 96: 369–374
- Grundemar L, Wohlfart B, Lagerstedt C, Bengtsson F, Eklundh G. Symptoms and signs of severe citalopram overdose. Lancet 1997; 349: 1602
- Ho R, Norman RF, van Veen MM, Anderson IB. A 3-year review of citalopram and escitalopram ingestions. [abstract]. J Toxicol Clin Toxicol 2004; 42: 746
- Kelly CA, Dhaun N, Laing WJ, Strachan FE, Good AM, Bateman DN. Comparative toxicity of citalopram and the newer antidepressants after overdose. J Toxicol Clin Toxicol 2004; 42: 67–71
- Öström, Eriksson A, Thorson J, Spigset O. Fatal overdose with citalopram. Lancet 1996; 348: 339–340
- Boyer EW, Shannon M. The serotonin syndrome. N Engl J Med 2005; 352: 1112–1120
- http://www.fda.gov/medwatch/safety/2005/safety05.htm#Paxil3
- Gentile S. SSRIs in pregnancy and lactation: emphasis on neurodevelopmental outcome. CNS Drugs 2005; 19: 623–633
- Malm H, Klaukka T, Neuvonen PJ. Risks associated with selective serotonin reuptake inhibitors in pregnancy. Obstet Gynecol 2005; 106: 1289–1296
- Shaneyfelt TM, Mayo-Smith MF, Rothwangl J. Are guidelines following guidelines? The methodological quality of clinical practice guidelines in the peer-reviewed medical literature. JAMA 1999; 281: 1900–1905
- Shiffman RN, Shekelle P, Overhage JM, Slutsky J, Grimshaw J, Deshpande AM. Standardized reporting of clinical practice guidelines: a proposal from the Conference on Guideline Standardization. Ann Intern Med 2003; 139: 493–498
- Kuczmarski RJ, Ogden CL, Grummer-Strawn LM, Flegal KM, Guo SS, Wei R, Mei Z, Curtin LR, Roche AF, Johnson CL. CDC Growth Charts: United States. Advance Data from Vital and Health Statistics; No. 314. National Center for Health Statistics, Hyattsville, MD 2000
- Benowitz NL. Antidepressants, general (noncyclic). Poisoning & drug overdose4th, KR Olson. McGraw Hill, New York 2004; 88–90
- Brent J. Serotonin reuptake inhibitors, newer antidepressants, and the serotonin syndrome. Clinical Toxicology, MD Ford, KA Delaney, LJ Ling, T Erickson. WB Saunders, Philadelphia 2001; 522–531
- Pentel PR, Keyler DE, Haddad LM. Tricyclic antidepressants and selective serotonin reuptake inhibitors. Clinical Management of Poisoning and Drug Overdose3rd, LM Haddad, MW Shannon, JF Winchester. WB Saunders, Philadelphia 1998; 437–451
- Whyte IM. Serotonin uptake inhibitors. Medical Toxicology3rd, RC Dart. Lippincott Williams & Wilkins, Philadelphia 2004; 843–851
- Nelson Textbook of Pediatrics17th, RE Behrman, RM Kliegman, HB Jenson. WB Saunders, Philadelphia 2004
- Lee C, Robertson J, Shilkofski N. Drug doses. The Harriet Lane Handbook: a Manual for Pediatric House Officers / the Harriet Lane Service, Children's Medical and Surgical Center of the Johns Hopkins Hospital, J Robertson, N Shilkofski. Elsevier Mosby, Philadelphia 2005
- http://www.fda.gov/cder/drug/antidepressants/SSRIPHA200410.htm
- Isbister GK, Dawson A, Whyte IM. Citalopram overdose, serotonin toxicity, or neuroleptic malignant syndrome?. Can J Psychiatry 2001; 46: 657–659
- Wijnands-Kleukers APG, van Zoelen G, de Dries I, Muelenbelt J. A prospective study on intoxications with citalopram [abstract]. J Toxicol Clin Toxicol 2002; 40: 274–275
- Baker SD, Morgan DL. Fluoxetine exposures: are they safe for children?. Am J Emerg Med 2004; 22: 211–213
- Barbey JT, Roose SP. SSRI safety in overdose. J Clin Psychiatry 1998; 59(Suppl 15)42–48
- Spiller HA, Morse S, Muir C. Fluoxetine ingestion: a one year retrospective study. Vet Hum Toxicol 1990; 32: 153–155
- Feierabend RH, Jr. Benign course in a child with a massive fluoxetine overdose. J Fam Pract 1995; 41: 289–291
- Garnier R, Azoyan P, Chataigner D, Taboulet P, Dellattre D, Efthymiou ML. Acute fluvoxamine poisoning. J Int Med Res 1993; 21: 197–208
- Fraser J, South M. Life-threatening fluvoxamine overdose in a 4-year-old child. Intensive Care Med 1999; 25: 548
- Myers LB, Dean BS, Krenzelok EP. Paroxetine (Paxil): overdose assessment of a new selective serotonin reuptake inhibitor [abstract]. Vet Hum Toxicol 1994; 36: 370
- Myers LB, Krenzelok EP. Paroxetine (Paxil) overdose: a pediatric focus. Vet Hum Toxicol 1997; 39: 86–88
- Baker SD, Vincent CB, Morgan DL. Paroxetine exposures: five-year analysis of unintentional ingestions in the pediatric population reported to the Texas Poison Center Network. [abstract]. J Toxicol Clin Toxicol 2003; 41: 712
- Klein-Schwartz W, Anderson B. Analysis of sertraline-only overdoses. Am J Emerg Med 1996; 14: 456–458
- Myers LB, Dean BS, Krenzelok EP. A closer look: sertraline (Zoloft) and pediatric overdoses [abstract]. J Toxicol Clin Toxicol 1995; 33: 551
- Lau GT, Horowitz BZ. Sertraline overdose. Acad Emerg Med 1996; 3: 132–136
- Catalano G, Cooper DS, Catalano MC, Guttman JM. Pediatric sertraline overdose. Clin Neuropharmacol 1998; 21: 59–61
- Pao M, Tipnis T. Serotonin syndrome after sertraline overdose in a 5‐year-old girl. Arch Pediatr Adolesc Med 1997; 151: 1064–1067
- Personne M, Persson H, Sjöberg E. Citalopram toxicity. Lancet 1997; 350: 518–519
- Personne M, Sjöberg G, Persson H. Citalopram overdose–review of cases treated in Swedish hospitals. J Toxicol Clin Toxicol 1997; 35: 237–240
- Aydin N, Anac E, Caykoylu A, Akcay F. Neuroleptic malignant syndrome due to citalopram overdose. Can J Psychiatry 2000; 45: 941–942
- Catalano G, Catalano MC, Epstein MA, Tsambiras PE. QTc interval prolongation associated with citalopram overdose: a case report and literature review. Clin Neuropharmacol 2001; 24: 158–162
- Cuenca PJ, Holt KR, Hoefle JD. Seizure secondary to citalopram overdose. J Emerg Med 2004; 26: 177–181
- Engebretsen KM, Harris CR, Wood JE. Cardiotoxicity and late onset seizures with citalopram overdose. J Emerg Med 2003; 25: 163–166
- Lepola U, Leinonen E, Koponen H. Serum drug levels and electroencephalographic findings after citalopram intoxication. Nord J Psychiatry 1996; 50: 61–62
- Rothenhausler HB, Hoberl C, Ehrentrout S, Kapfhammer HP, Weber MM. Suicide attempt by pure citalopram overdose causing long-lasting severe sinus bradycardia, hypotension and syncope: successful therapy with a temporary pacemaker. Pharmacopsychiatry 2000; 33: 150–152
- Snider RD. Case report: left bundle branch block–a rare complication of citalopram overdose. J S C Med Assoc 2001; 97: 380–382
- Tarabar AF, Hoffman RS, Nelson LS. Citalopram overdose: late presentation of torsades de pointes (TDP) with cardiac arrest [abstract]. J Toxicol Clin Toxicol 2003; 41: 676
- Penfornis C, Hueber-Paysant V, Souplet JP, Curtes JP, Caubet A. Fatal case of citalopram intoxication [abstract]. Vet Hum Toxicol 1998; 40: 178
- Lindgren KN, Bangh SA, Ling L, Stremski E, Mueller C. Escitalopram, a review of adverse effects in overdose reported to select regional poison center [abstract]. J Toxicol Clin Toxicol 2003; 41: 658
- Olsen DG, Dart RC, Robinett M. Severe serotonin syndrome from escitalopram overdose [abstract]. J Toxicol Clin Toxicol 2004; 42: 744–745
- Borys DJ, Setzer SC, Ling LJ, Reisdorf JJ, Day LC, Krenzelok EP. The effects of fluoxetine in the overdose patient. J Toxicol Clin Toxicol 1990; 28: 331–340
- Cooper GL. The safety of fluoxetine--an update. Br J Psychiatry Suppl 1988; 77–86
- Braitberg G, Curry SC. Seizure after isolated fluoxetine overdose. Ann Emerg Med 1995; 26: 234–237
- Finnegan KT, Gabiola JM. Fluoxetine overdose. Am J Psychiatry 1988; 145: 1604
- Graudins A, Vossler C, Wang R. Fluoxetine-induced cardiotoxicity with response to bicarbonate therapy. Am J Emerg Med 1997; 15: 501–503
- Gross R, Dannon PN, Lepkifker E, Zohar J, Kotler M. Generalized seizures caused by fluoxetine overdose. Am J Emerg Med 1998; 16: 328–329
- Grover J, Caravati EM. Right bundle branch block and delayed seizure associated with citalopram and fluoxetine ingestion [abstract]. J Toxicol Clin Toxicol 2001; 39: 491
- Kim SW, Pentel PR. Flu-like symptoms associated with fluoxetine overdose: a case report. J Toxicol Clin Toxicol 1989; 27: 389–393
- Kincaid RL, McMullin MM, Crookham SB, Rieders F. Report of a fluoxetine fatality. J Anal Toxicol 1990; 14: 327–329
- Kious T, Wax P, Cobaugh D. Tramadol and fluoxetine induced serotonin syndrome with subsequent severe hyperpyrexia despite cyproheptadine [abstract]. J Toxicol Clin Toxicol 1999; 37: 631–632
- Lherm T, Lottin F, Larbi D, Bray M, Legall C, Caen D. Torsade de pointes après intoxication monomedicamenteuse à la fluoxetine. Presse Med 2000; 29: 306–307
- Moore JL, Rodriguez R. Toxicity of fluoxetine in overdose. Am J Psychiatry 1990; 147: 1089
- Riddle MA, Brown N, Dzubinski D, Jetmalani AN, Law Y, Woolston JL. Fluoxetine overdose in an adolescent. J Am Acad Child Adolesc Psychiatry 1989; 28: 587–588
- Henry JA. Overdose and safety with fluvoxamine. Int Clin Psychopharmacol 1991; 6(Suppl 3)41–45
- Martin AJ, Tebbs VM, Ashford JJ. Affective disorders in general practice. Treatment of 6000 patients with fluvoxamine. Pharmatherapeutica 1987; 5: 40–49
- Amital D, Amital H, Gross R, Kindler S, Zohar J. Sinus bradycardia due to fluvoxamine overdose. Br J Psychiatry 1994; 165: 553–554
- Banerjee AK. Recovery from prolonged cerebral depression after fluvoxamine overdose. Br Med J (Clin Res Ed) 1988; 296: 1774
- Buchberger R, Wagner W. Fluvoxamine: safety profile in extensive post-marketing surveillance. Pharmacopsychiatry 2002; 35: 101–108
- Chen Y, Barboteu M, Taboulet P, Le Gall JR. Convulsions et arrêt circulatoire lors d'une intoxication par la fluvoxamine et la paroxetine. Therapie 1998; 53: 165–167
- Gill M, LoVecchio F, Selden B. Serotonin syndrome in a child after a single dose of fluvoxamine. Ann Emerg Med 1999; 33: 457–459
- Hahn I, Blancaflor G, Hoffman RS, Howland MA, Nelson LS. Fluvoxamine overdose producing status epilepticus [abstract]. J Toxicol Clin Toxicol 2000; 38: 573
- Langlois RP, Paquette D. Sustained bradycardia during fluvoxamine and buspirone intoxication. Can J Psychiatry 1994; 39: 126–127
- Lebegue B. Survivable fluvoxamine overdose. Am J Psychiatry 1990; 147: 1689
- Manet P, Hilpert F, Fouet P, Toledano D. Troubles du rythme ventriculaire lors d'une intoxication à la fluvoxamine. Therapie 1993; 48: 62–63
- De Riu PL, Rosati G, Sotgiu S, Sechi G. Epileptic seizures after treatment with thiocolchicoside. Epilepsia 2001; 42: 1084–1086
- Greb WH, Buscher G, Dierdorf HD, von Schrader HW, Wolf D. Ability of charcoal to prevent absorption of paroxetine. Acta Psychiatr Scand Suppl 1989; 350: 156–157
- Lund J, Lomholt B, Fabricius J, Christensen JA, Bechgaard E. Paroxetine: pharmacokinetics, tolerance and depletion of blood 5-HT in man. Acta Pharmacol Toxicol (Copenh) 1979; 44: 289–295
- Christensen O, Sorensen HA, Almdal TP. Bivirkninger ved behandling med selektive serotoningenoptagelseshaemmere. Hyponotrioemi pa grund af Schwartz-Bartters syndrome. Ugeskr Laeger 1996; 158: 6920–6922
- Dunbar GC. An interim overview of the safety and tolerability of paroxetine. Acta Psychiatr Scand Suppl 1989; 350: 135–137
- Gorman SE, Rice T, Simmons HF. Paroxetine overdose. Am J Emerg Med 1993; 11: 682
- Graeme K, Curry S, Kunkel D. Delayed cardiotoxicity after haloperidol and paroxetine overdose [abstract]. J Toxicol Clin Toxicol 1999; 37: 635
- Johnsen CR, Hoejlyng N. Hyponatremia following acute overdose with paroxetine. Int J Clin Pharmacol Ther 1998; 36: 333–335
- Johnson R, Velez LI, Roth B. Paroxetine as a sole cause of serotonin syndrome: a massive overdose with documented serum paroxetine levels [abstract]. J Toxicol Clin Toxicol 2001; 39: 491
- Robert P, Senard JM, Fabre M, Cabot C, Cathala B. Syndrome sétoninergique lors d'une intoxication aiguë aux antidépresseurs. Ann Fr Anesth Reanim 1996; 15: 663–665
- Velez LI, Shepherd G, Roth BA, Benitez FL. Serotonin syndrome with elevated paroxetine concentrations. Ann Pharmacother 2004; 38: 269–272
- Waksman JC, Heard K, Jolliff H, Daly FFS, Bogdan GM, Dart RC. Serotonin syndrome associated with the use of St. John's wort (Hypericum perforatum) and paroxetine. [abstract]. J Toxicol Clin Toxicol 2000; 38: 521
- Mattila MJ, Saarialho-Kere U, Mattila M. Acute effects of sertraline, amitriptyline, and placebo on the psychomotor performance of healthy subjects over 50 years of age. J Clin Psychiatry 1988; 49(Suppl)52–58
- Brendel DH, Bodkin JA, Yang JM. Massive sertraline overdose. Ann Emerg Med 2000; 36: 524–526
- Brown DF, Kerr HD. Sertraline overdose. Ann Pharmacother 1994; 28: 1307
- Caracci G. Unsuccessful suicide attempt by sertraline overdose. Am J Psychiatry 1994; 151: 147
- Kaminski CA, Robbins MS, Weibley RE. Sertraline intoxication in a child. Ann Emerg Med 1994; 23: 1371–1374
- Lopez Gaston OD, Wierzbinsky S, Lopez Gaston RS, Resnik S, Pardomenico S, Jorge M. Sertralina. Efectos adversos por superposicion de manifestaciones de sindromes serotoninico y neuroléptico maligno. Medicina (B Aires) 2000; 60: 241–244
- Meier K, Lam R. 4 gram sertraline (Zoloft®) overdose resulting in delayed seizures [abstract]. J Toxicol Clin Toxicol 1998; 36: 520–521
- Mordel A, Linden CH. Marked sinus tachycardia following sertraline overdose [abstract]. J Toxicol Clin Toxicol 1998; 36: 521
- Vanberkum M, Thiel J, Leikin J, Segovia A. A fatality due to serotonin syndrome [abstract]. J Toxicol Clin Toxicol 1996; 34: 539–540
- Laine K, Kivisto KT, Pelttari S, Neuvonen PJ. The effect of activated charcoal on the absorption of fluoxetine, with special reference to delayed charcoal administration. Pharmacol Toxicol 1996; 79: 270–273
- Lapatto-Reiniluoto O, Kivisto KT, Neuvonen PJ. Effect of activated charcoal alone or given after gastric lavage in reducing the absorption of diazepam, ibuprofen and citalopram. Br J Clin Pharmacol 1999; 48: 148–153
- Isbister GK, Dawson AH, Whyte IM. Feasibility of prehospital treatment with activated charcoal: who could we treat, who should we treat?. Emerg Med J 2003; 20: 375–378
- Phillips S, Brent J, Kulig K, Heiligenstein J, Birkett M. Fluoxetine versus tricyclic antidepressants: a prospective multicenter study of antidepressant drug overdoses. The Antidepressant Study Group. J Emerg Med 1997; 15: 439–445
- Brucculeri M, Kaplan J, Lande L. Reversal of citalopram-induced junctional bradycardia with intravenous sodium bicarbonate. Pharmacotherapy 2005; 25: 119–122
- Caravati EM. Unintentional acetaminophen ingestion in children and the potential for hepatotoxicity. J Toxicol Clin Toxicol 2000; 38: 291–296
- Henry JA. Epidemiology and relative toxicity of antidepressant drugs in overdose. Drug Saf 1997; 16: 374–390
- Isbister GK, Bowe SJ, Dawson A, Whyte IM. Relative toxicity of selective serotonin reuptake inhibitors (SSRIs) in overdose. J Toxicol Clin Toxicol 2004; 42: 277–285