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Letter to the Editor

Reply to: “Amitriptyline-induced Brugada pattern fails to respond to sodium bicarbonate”

, M.D. & , DABT , MD
Pages 90-91 | Published online: 20 Jan 2009

References

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  • Sasyniuk BI, Jhamandas V. Mechanism of reversal of toxic effects of amitriptyline on cardiac Purkinje fibers by sodium bicarbonate. J Pharmacol Exp Ther 1984; 231(2)387–94
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  • Pentel P, Benowitz N. Efficacy and mechanism of action of sodium bicarbonate in the treatment of desipramine toxicity in rats. J Pharmacol Exp Ther 1984; 230(1)12–9
  • Nattel S, Mittleman M. Treatment of ventricular tachyarrhythmias resulting from amitriptyline toxicity in dogs. J Pharmacol Exp Ther 1984; 231(2)430–5
  • Bebarta VS, Phillips S, Eberhardt A, Calihan KJ, Heard K, Waksman J. Incidence and outcomes of patients with the Brugada pattern in a large case series of tricyclic overdoses. J Toxicol Clin Toxicol 2004; 42(5)714

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