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Research Article

CroFab® reconstitution in various media: an in vitro solubility study

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Pages 808-810 | Received 25 May 2007, Accepted 31 Mar 2008, Published online: 02 Dec 2008

References

  • CroFab package insert. Savage Laboratories, Protherics WC. Brentwood, TN, 2006.
  • RC Dart, SA Seifert, L Carroll, RF Clark, E Hall, LV Boyer-Hassen, SC Curry, CS Kitchens, and RA Garcia. Affinity-purified, mixed monospecific crotalid antivenom ovine Fab for the treatment of crotalid venom poisoning. Ann Emerg Med 1997; 30 (1):33–39.
  • RC Dart, SA Seifert, LV Boyer, RF Clark, E Hall, P McKinney, J McNally, CS Kitchens, SC Curry, GM Bogdan, SB Ward, and RS Porter. A randomized multicenter trial of crotalinae polyvalent immune Fab (ovine) antivenom for the treatment for crotaline snakebite in the United States. Arch Intern Med 2001; 161 (16):2030–2036.
  • RE Hill, GM Bogdan, and RC Dart. Time to reconstitution: purified Fab antivenom vs. unpurified IgG antivenom. Toxicon 2001; 39 (5):729–731.
  • AD Kanavage, LV Boyer, J McNally, and JJ Osterhout. Resistance of antivenom proteins to foaming-induced denaturation. Toxicon 2006; 47 (4):445–452.
  • WW Decker, GM Bogdan, RA Garcia, P Wollen, and RC Dart. Heat and motion stability of polyvalent Crotalidae antivenin, ovine Fab. Toxicon 1998; 36 (2):377–382.
  • PA Goldberg, A Kedves, K Walter, A Groszmann, A Belous, and SE Inzucchi. “Waste not, want not”: determining the optimum priming volume in insulin infusions. Diabetes Technol Ther 2006; 8 (5):598–601.

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