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Case Report

Toxicokinetics and toxicodynamics of elemental mercury following self-administration

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Pages 869-876 | Received 29 Nov 2007, Accepted 17 Apr 2008, Published online: 02 Dec 2008

References

  • WL Hughes. A physicochemical rationale for the biological activity of mercury and its compounds. Ann N Y Acad Sci 1957; 65:454–460.
  • L Magos, and TW Clarkson. Overview of the clinical toxicity of mercury. Ann Clin Biochem 2006; 43:257–268.
  • JB Hursh. Partition coefficients of mercury (203 Hg) vapor between air and biological fluids. J Appl Toxicol 1985; 5:327–332.
  • NC Cowan, P Kane, and J Karani. Case report: metallic mercury embolism-deliberate self-injection. Clin Radiol 1992; 46:357–358.
  • EH Kayias, GI Drosos, D Hapsas, and GA Anagnostopoulou. Elemental mercury-induced subcutaneous granuloma. A case report and review of the literature. Acta Orthop Belg 2003; 69:280–284.
  • RH Gadsden, GB Bradham, JT BuxtonJr, and JC Hewitt. Metallic mercury embolism: report of cases. J Am Med Assoc 1965; 193:573–575.
  • HB Devlin, and M Sudlow. Peripheral mercury embolization occurring during arterial blood sampling. Br Med J 1967; 1:347–348.
  • E Schulz, and H Beskind. Systemic deposition of metallic mercury. J Pediatr 1960; 57:733–737.
  • R Chitkara, NS Seriff, and HY Kinas. Intravenous self-administration of metallic mercury in attempted suicide. Chest 1978; 73:234–236.
  • F Eyer, N Felgenhauer, R Pfab, G Drasch, and T Zilker. Neither DMPS nor DMSA is effective in quantitative elimination of elemental mercury after intentional IV injection. Clin Toxicol (Phila) 2006; 44:395–397.
  • RJ Giombetti, DH Rosen, AR Kuczmierczyk, and DO Marsh. Repeated suicide attempts by the intravenous injection of elemental mercury. Int J Psychiatry Med 1988; 18:153–167.
  • M Díaz-Sánchez, FJ Martínez-Lagares, WR Castaned, A Givica Pérez, and JM Santana Montesdeoca. Deliberate, repeated self-administration of metallic mercury injection: case report and review of the literature. Eur Radiol 2001; 11:1351–1354.
  • JW Gulden, F Christ, E Hauser, and HJ Kramer. Circulatory distribution of intravenously injected metallic mercury. Rontgenblatter 1987; 40:401–405.
  • HT Haffner, J Erdelkamp, E Goller, F Schweinsberg, and V Schmidt. Morphological and toxicological findings after intravenous injection of metallic mercury. Dtsch Med Wochenschr 1991; 116:1342–1346.
  • H Hohage, B Otte, G Westermann, J Witta, U Welling, W Zidek, and S Heidenreich. Elemental mercurial poisoning. South Med J 1997; 90:1033–1036.
  • HRM Johnson, and O Koumides. Unusual case of mercury poisoning. Br Med J 1967; 1:340–341.
  • A Kedziora, and J Duflou. Attempted suicide by intravenous injection of mercury: a rare cause of cardiac granulomas. A case report. Am J Forensic Med Pathol 1995; 16:172–176.
  • V Maniatis, G Zois, and K Stringaris. IV mercury self-injection: CT imaging. AJR Am J Roentgenol 1997; 169:1197–1198.
  • RB McFee, and TR Caraccio. Intravenous mercury injection and ingestion: clinical manifestations and management. J Toxicol Clin Toxicol 2001; 39:733–738.
  • P Nalepa, T Lech, and W Kotucha. Intravenous injection of metallic mercury: case report. Pneumonol Alergol Pol 1996; 64:88–92.
  • C Papadopoulos, N Vasile, JP Richard, and JL Renard. Mercury pulmonary embolism. Two case reports. Rev Pneumol Clin 1999; 55:43–46.
  • N Peterson, W Harvey-Smith, and CA Rohrmann. Radiographic aspects of metallic mercury embolism. AJR Am J Roentgenol 1980; 135:1079–1081.
  • IM Rodrigues, ND Hopkinson, and RI Harris. Pulmonary embolism associated with self-administration of mercury. Hum Toxicol 1986; 5:287–289.
  • L Garza-Ocanas, A Pineyro-Lopez, and O Torres Alanis. Intravenous self-administration of metallic mercury: report of a case with a 5-year follow-up. J Toxicol Clin Toxicol 1997; 35:83–87.
  • F Umber. Quecksilber-Embolien der lebenden Lunge durch intravenose Injektion von metallischem Quecksilber. Med Klin 1923; 19:35.
  • E Walter. Long-term observation of a case of intravenous injection of elemental mercury. Radiologe 1986; 26:40–46.
  • G Wedekind, and D Beyer. Multiple microembolization caused by elemental mercury. Radiologe 1994; 34:483–486.
  • R Winker, AW Schaffer, C Konnaris, A Barth, P Giovanoli, W Osterode, HW Rudiger, and C Wolf. Health consequences of an intravenous injection of metallic mercury. Int Arch Occup Env Health 2002; 75:581–586.
  • A Kumar, R Jain, S Sawhney, AK Goel, and K Chattopadhyay. Intravenous administration of metallic mercury with homicidal intent. J Assoc Physicians India 1992; 40:640–641.
  • JJ Ambre, MJ Welch, and CW Svare. Intravenous elemental mercury injection: blood levels and excretion of mercury. Ann Intern Med 1977; 87:451–453.
  • Z Chodorowski, and JS Anand. Intravenous self-administration of metallic mercury by two alcohol abusers. Przegl Lek 2000; 57:585–587.
  • ME Conrad, JP Sanford, and JA Preston. Metallic mercury embolization; clinical and experimental. Arch Intern Med 1957; 100:59–65.
  • MA De Ruggieri, E Pampiglione, B Annicchiarico Petruzzelli, and A Aurizi. A case of embolism caused by metallic mercury in a drug addict. Ann Ig 1989; 1:673–678.
  • E Naidich, D Bartelt, P Wheeler, and W Stern. Metallic mercury emboli. Am J Roentgenol Radium Ther Nucl Med 1973; 117:886–891.
  • H Ochs, I Boldt, W Messerschmidt, and U Boldt. Intravenous injection of thermometer mercury. Munch Med Wochenschr 1975; 117:1117–1120.
  • MG Stahl, HW Bonekat, and JW Shigeoka. Concomitant pulmonary thromboembolism and metallic mercury embolism. Chest 1985; 88:787–789.
  • B Celli, and MA Khan. Mercury embolization of the lung. New Engl J Med 1976; 295:883–885.
  • Z Chodorowski, and J Sein Anand. Repeated metallic mercury intravenous injection for doping. Przegl Lek 2002; 59:377–378.
  • SV Manoukian, and NK Wenger. Mercury in the heart. Am J Cardiol 1991; 67:317–318.
  • F Deschamps, C Strady, G Deslee, B Menciere-Faroy, and S Deschamps. Five years of follow-up after elemental mercury self-poisoning. Am J Forensic Med Pathol 2002; 23:170–172.
  • SE Rossi, PC Goodman, and T Franquet. Nonthrombotic pulmonary emboli. AJR Am J Roentgenol 2000; 174:1499–1508.
  • P Apostoli, A Colombi, M Buratti, G Elia, C Flore, P Carta, A Ibba, I Cortesi, A Mangili, and L Alessio. Evaluation of the dose of mercury in exposed and control subjects. Med Lav 2002; 93:159–175.
  • M Dell'Omo, G Muzi, A Bernard, S Filiberto, RR Lauwerys, and G Abbritti. Long-term pulmonary and systemic toxicity following intravenous mercury injection. Arch Toxicol 1997; 72:59–62.
  • JL Lin, and PS Lim. Massive oral ingestion of elemental mercury. J Toxicol Clin Toxicol 1993; 31:487–492.
  • N Wright, WB Yeoman, and GF Carter. Massive oral ingestion of elemental mercury without poisoning. Lancet 1980; 1:206.
  • SJ Balk. Resources for pediatricians. How do I answer questions from parents, patients, teachers, and others?. Pediatr Clin North Am 2001; 48:1099–1111.viii.
  • M Berlin. Handbook of the Toxicology of Metals. L Friberg, GF Nordberg, and VB Vouk. Specific metals. Amsterdam/New York/Oxford: Elsevier; 1990: II387–445.
  • P Davey, and M Benson. A young man with a heavy heart. Hearth 1999; 82:e11.
  • T Konopka, P Nalepa, and E Rzepecka-Wozniak. Long-term survival after a suicidal intravenous injection of mercury. Arch Med Sadowej Kryminol 2006; 56:267–270.
  • CR Larios, S Gonzalo Tropez, O Raudales, and C Barahona. Pulmonary hydrargyrosis. Bull Am Coll Physicians 1970; 9:22.
  • BG Hanningan. Self-administration of metallic mercury by intravenous injection. Br Med J 1978; 2:933.
  • KM Murray, and JC Hedgepeth. Intravenous self-administration of elemental mercury: efficacy of dimercaprol therapy. Drug Intell Clin Pharm 1988; 22:972–975.
  • BA Fowler. Mechanisms of kidney cell injury from metals. Environ Health Perspect 1993; 100:57–63.
  • EM Souza, ML Cintra, VG Melo, RJ Vieira, EM De Capitani, and FA Zambrone. Subcutaneous injection of elemental mercury with distant skin lesions. J Toxicol Clin Toxicol 2000; 38:441–443.
  • NI McNeil, HC Issler, RE Olver, and OM Wrong. Domestic metallic mercury poisoning. Lancet 1984; 1:269–271.
  • TW Clarkson. Mercury. J Am Coll Toxicol 1989; 8:1291–1296.
  • L Zolla, G Lupidi, A Bellelli, and G Amiconi. Effect of mercuric ions on human erythrocytes. Relationships between hypotonic swelling and cell aggregation. Biochim Biophys Acta 1997; 1328:273–280.
  • HB Gerstner, and JE Huff. Clinical toxicology of mercury. J Toxicol Environ Health 1977; 2:491–526.
  • M Goldoni, S Catalani, G De Palma, P Manini, O Acampa, M Corradi, R Bergonzi, P Apostoli, and A Mutti. Exhaled breath condensate as a suitable matrix to assess lung dose and effects in workers exposed to cobalt and tungsten. Environ Health Perspect 2004; 112:1293–1298.
  • J Aaseth, J Alexander, and N Raknerud. Treatment of mercuric chloride poisoning with dimercaptosuccinic acid and diuretics: preliminary studies. J Toxicol Clin Toxicol 1982; 19:173–186.
  • S Suzuki, and N Ozaki. The protective effects of thiol-containing compounds on mercuric chloride-induced acute inhibition of enzymes from mouse kidney. Toxicology 1984; 29:207–220.

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