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Brief Communications

Serotonin syndrome following sibutramine poisoning in a child, with sequential quantification of sibutramine and its primary and secondary amine metabolites in plasma

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Pages 598-601 | Received 17 Mar 2009, Accepted 04 May 2009, Published online: 08 Jul 2009

References

  • Luque CA, Rey JA. Sibutramine: a serotonin-norepinephrine reuptake-inhibitor for the treatment of obesity. Ann Pharmacother 1999; 33:968–978.
  • Yim KM, Ng HW, Chan CK, Yip G, Lau FL. Sibutramine-induced acute myocardial infarction in a young lady. Clin Toxicol (Phila) 2008; 46:877–879.
  • Phan H, Casavant MJ, Crockett S, Lee A, Hall MW, Nahata MC. Serotonin syndrome following a single 50 mg dose of sertraline in a child. Clin Toxicol (Phila) 2008; 46:845–849.
  • Jain DS, Subbaiah G, Sanyal M, Shrivastav PS, Pal U, Ghataliya S, Kakad A, Patel H, Shah S. Liquid chromatography/electrospray ionization tandem mass spectrometry validated method for the simultaneous quantification of sibutramine and its primary and secondary amine metabolites in human plasma and its application to a bioequivalence study. Rapid Commun Mass Spectrom 2006; 20:3509–3521.
  • Alertas Estaduais de Farmacovigilância. Alerta Terapêutico n° 03/01, março de 2002 – Sibutramina. Secretaria de Estado da Saúde, Centro de Vigilância Sanitária, Divisão Técnica de Produtos Relacionados à Saúde. http://www.anvisa.gov.br/farmacovigilancia/alerta/estadual/estadual_3.htm. Accessed 25 February 2009.
  • Park JY, Kim KA, Park PW, Suh KH, Lee GS. Relative bioavailability and pharmacokinetics of a new sibutramine formulation in healthy male subjects: a randomized, open-label, two-period, comparative crossover study. Clin Ther 2004; 26:2092–2101.
  • Ernest D, Gershenzon A, Corallo CE, Nagappan R. Sibutramine-associated QT interval prolongation. Ann Pharmacother 2008; 42:1514–1517.
  • Lee J, Teoh T, Lee TS. Catatonia and psychosis associated with sibutramine: a case report and pathophysiologic correlation. J Psychosom Res 2008; 64:107–109.
  • Chounta A, Tsiodras S, Zouridakis S, Doumas M, Giamarellou H. Sibutramine use associated with reversible hepatotoxicity. Ann Intern Med 2005; 143:763–764.
  • Esposito P, Rampino T, Gregorini M, Soccio G, Piotti G, Bedino G, Balenzano CT, Roscini E, Cosmai L, Portalupi V, Libetta C, Dal Canton A. Severe symptomatic hyponatremia during sibutramine therapy: a case report. Am J Kidney Dis 2008; 52:137–139.
  • Brvat M, Stajer D, Kozelj G, Osredkar J, Mozina M, Bunc M. Urinary serotonin level is associated with serotonin syndrome after moclobemide, sertraline, and citalopram overdose. Clin Toxicol (Phila) 2007; 45:458–460.

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