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Research Article

GENETIC DIVERSITY IN SNAKE VENOM THREE-FINGER PROTEINS AND PHOSPHOLIPASE A2 ENZYMES

Pages 143-167 | Published online: 11 Oct 2008

References

  • Afifiyan F., Armugam A., Tan C. H., Gopalakrishnakone P., Jeyaseelan K. Postsynaptic α-neurotoxin gene of the spitting cobra, Naja naja sputatrix: structure, organization and phylogenetic analysis. Genome Res. 1999; 9: 259–266
  • Aird S. D., Womble G. C., Yates J. R., Griffin P. R. Primary structure of γ-bungarotoxin, a new postsynaptic neurotoxin from the venom of Bungarus multicinctus. Toxicon 1999; 37: 609–625
  • Armugam A., Gong N., Li X., Siew P. Y., Chai S. C., Nair R., Jeyaseelan K. Group IB phospholipase A2 from Pseudonaja textilis. Arch. Biochem. Biophys. 2004; 421: 10–20
  • Chang L. S., Chou Y. C., Lin S. R., Wu B. N., Lin J., Hong E., Sun Y. J., Hsiao C. D. A novel neurotoxin, cobrotoxin b, from Naja naja atra (Taiwan cobra) venom: purification, characterization and gene organization. J. Biochem. 1997; 122: 1252–1259
  • Chang L. S., Chung C., Lin J., Hong E. Organization and phylogenetic analysis of κ-bungarotoxin genes from Bungarus multicinctus (Taiwan banded krait). Genetica 2002a; 115: 213–221
  • Chang L. S., Chung C., Liou J. C., Chang C. W., Yang C. C. Novel neurotoxins from Taiwan banded krait (Bungarus multicinctus) venom: purification, characterization and gene organization. Toxicon 2003; 42: 323–330
  • Chang L. S., Chung C., Wu B. N., Yang C. C. Characterization and gene organization of Taiwan banded krait (Bungarus multicinctus) γ-bungarotoxin. J. Protein Chem. 2002b; 21: 223–229
  • Chang L. S., Hong E. SnoRNA from Naja naja atra (Taiwan cobra) and Bungarus multicinctus (Taiwan banded krait), formed sequence complementarity to 5S rRNA. Biochem. Biophys. Res. Commun. 1997; 236: 782–784
  • Chang L. S., Lin J. cDNA sequence analysis of a novel neurotoxin homology from Taiwan banded krait. Biochem. Mol. Biol. Int. 1997; 43: 347–354
  • Chang L. S., Lin J., Chou Y. C., Hong E. Genomic structures of cardiotoxin 4 and cobrotoxin from Naja naja atra (Taiwan cobra). Biochem. Biophys. Res. Commun. 1997; 239: 756–762
  • Chang L. S., Lin J., Wu P. F. cDNA sequence and expression of cardiotoxin V and a new cardiotoxin VII from Naja naja atra (Taiwan cobra). Biochim. Biophys. Acta 1996; 1295: 1–4
  • Chang L. S., Lin J., Wu P. F., Chang C. C., Hung E. cDNA sequence analysis and expression of κ-bungarotoxin from Taiwan banded krait. Biochem. Biophys. Res. Commun. 1997; 230: 192–195
  • Chang L. S., Lin S. K., Chung C. Molecular cloning and evolution of the genes encoding the precursors of Taiwan cobra cardiotoxin and cardiotoxin-like basic protein. Biochem. Genetics 2004; 42: 429–440
  • Chang L. S., Lin S. K., Huang S. B., Hsiao M. Genetic organization of α-bungarotoxins from Bungarus multicinctus (Taiwan banded krait): Evidence showing that the production of α-bungarotoxin isotoxins is not derived from edited mRNAs. Nucleic Acids Res. 1999; 27: 3970–3975
  • Chang L. S., Lin S. K., Wu P. F. Differentially expressed snoRNAs in Bungarus multicinctus (Taiwan banded krait). Biochem. Biophys. Res. Commun. 1998; 245: 397–402
  • Chang L. S., Lin S. R., Wang J. J., Hu W. P., Wu B. N., Huang H. B. Structure-function studies on Taiwan cobra long neurotoxin homolog. Biochim. Biophys. Acta 2000; 1480: 293–301
  • Chang L. S., Wu P. F., Lin J. cDNA sequence analysis and expression of cardiotoxins from Taiwan cobra. Biochem. Biophys. Res. Commun. 1996; 219: 116–121
  • Chiappinelli V. A. κ-Neurotoxins and α-neurotoxins: effects on neuronal nicotinic acetylcholine receptors. Snake Toxins, A. L. Harvey. Pergamon Press, New York, 223–258
  • Chu Y. P., Chang L. S. The organization of the genes encoding the A chain of β-bungarotoxins: evidence for the skipping of exon. Toxicon 2002; 40: 1437–1443
  • Chung C., Wu B. N., Yang C. C., Chang L. S. Muscarinic toxin-like proteins from Taiwan banded krait (Bungarus multicinctus) venom: purification, characterization and gene organization. Biol. Chem. 2002; 383: 1397–1406
  • Daltry J. C., Ponnudurai G., Shin C. K., Tan N. H., Thorpe R. S., Wuster W. Electrophoretic profiles and biological activities: intraspecific variation in the venom of the Malayan pit viper (Calloselasma rhodostoma). Toxicon 1996; 34: 67–79
  • Daltry J. C., Wuster W., Thorpe R. S. Diet and snake venom evolution. Nature 1996; 379: 537–540
  • Danse J. M., Garnier J. M., Kempf J. cDNA deduced amino-acid sequence of a new phospholipase from Bungarus multicinctus. Nucleic Acids Res. 1990; 18: 4610
  • Danse J. M., Gasparini S., Menez A. Molecular biology of snake venom phospholipases A2. Venom Phospholipase A2 Enzymes: Structure, Function and Mechanism, R. M. Kini. John Wiley & Sons, New York 1997; 29–71
  • Danse J. M., Toussaint J. L., Kempf J. Nucleotide sequence encoding β-bungarotoxin A2 chain from the venom glands of Bungarus multicinctus. Nucleic Acids Res. 1990; 18: 4609
  • Dewan J. C., Grant G. A., Sacchettini J. C. Crystal structure of kappa-bungarotoxin at 2.3 Å resolution. Biochemistry 1994; 33: 13147–13154
  • Ducancel F., Bouchier C., Tamiya T., Boulain J. C., Menez A. Cloning and expression of toxin cDNAs. Snake Toxins, A. L. Harvey. Pergamon Press, New York 1991; 385–414
  • Ducancel F., Rowan E. G., Cassart E., Harvey A., Menez A., Boulain J. C. Amino acid sequence of a muscarinic toxin deduced from the cDNA sequence. Toxicon 1991; 29: 516–520
  • Endo T., Tamiya N. Structure-function relationship of postsynaptic neurotoxins from snake venoms. Snake Toxins, A. L. Harvey. Pergamon Press, New York 1991; 165–222
  • Fujimi T. J., Nakajyo T., Nishimura E., Ogura E., Tsuchiya T., Tamiya T. Molecular evolution and diversification of snake toxin genes, revealed by analysis of intron sequences. Gene 2003; 313: 111–118
  • Fujimi T. J., Tsuchiga T., Tamiya T. A comparative analysis of invaded sequences from group IA phospholipase A2 genes provides evidence about the divergence period of genes groups and snake families. Toxicon 2002; 40: 873–884
  • Fuse N., Tsuchiya T., Nonomura Y., Menez A., Tamiya T. Structure of the short-chain neurotoxin, erabutoxin c, precursor gene. Eur. J. Biochem. 1990; 629–633
  • Gong N., Armugam A., Jeyaseelan K. Molecular cloning, characterization and evolution of the gene encoding a new group of short-chain α-neurotoxins in an Australian elapid, Pseudonaja textilis. FEBS Lett. 2000; 473: 303–310
  • Gong N. L., Armugam A., Mirtschin P., Jeyaseelan K. Cloning and characterization of the pseudonajatoxin b precursor. Biochem. J. 2001; 358: 647–656
  • Guignery-Frelat G., Ducancel F., Menez A., Boulain J. C. Sequence of a cDNA encoding a snake venom phospholipase A2. Nucleic Acid Res. 1987; 15: 5892
  • Harris J. B. Phospholipases in snake venoms and their effects on nerve and muscle. Snake Toxins, A. L. Harvey. Pergamon Press, New York 1991; 91–129
  • Heinrikson R. L., Kruger E., Keim P. S. Amino acid sequence of phospholipase A2-α from the venom of Crotalus adamenteus, a new classification of phospholipase A2 based upon structural determinants. J. Biol. Chem. 1977; 252: 4913–4921
  • Jeyaseelan K., Armugam A., Ma D., Tan N. H. Structure and phylogeny of the venom group I phospholipase A2 gene. Mol. Biol. Evol. 2000; 17: 1010–1021
  • Jeyaseelan K., Ma D., Armugam A. Real-time detection of gene promoter activity: Quantitation of toxin gene transcription. Nucleic Acids. Res. 2001; 29: E58–8
  • Jeyaseelan K., Poh S. L., Nair R., Armugam A. Structurally conserved α-neurotoxin genes encode functionally diverse proteins in the venom of Naja sputatrix. FEBS Lett. 2003; 553: 333–341
  • John T. R., Smith L. A., Kaiser I. I. Genomic sequences encoding the acidic and basic subunits of mojave toxin: unusually high sequence identity of non-coding regions. Gene 1994; 139: 229–234
  • Kini R. M. Phospholipase A2: a complex multifunctional protein puzzle. Venom Phospholipase A2 Enzymes: Structure, Function and Mechanism, R. M. Kini. John Wiley & Sons, New York 1997; 1–28
  • Kordis D., Bdolah A., Gubensek F. Positive Darwinian selection in Vipera palaestinae phospholipase A2 genes is unexpectedly limited to the third exon. Biochem. Biophys. Res. Commun. 1998; 251: 613–619
  • Kordis D., Gubensek F. Adaptive evolution of animal toxin multigene families. Gene 2000; 261: 43–52
  • Kordis D., Gubensek F. Ammodytoxin C gene helps to elucidate irregular structure of Crotalinae group II phospholipase A2 genes. Eur. J. Biochem. 1996; 83–90
  • Kordis D., Gubensek F. Bov-B long interspersed repeated DNA (LINE) sequences are presented in Vipera ammodytes phospholipase A2 genes and in genome of Viperidae snakes. Eur. J. Biochem. 1997; 246: 772–779
  • Lachumanan R., Armugam A., Tan C. H., Jeyaseelan K. Structure and organization of the cardiotoxin genes in Naja naja sputatrix. FEBS Lett. 1998; 433: 119–124
  • Ma D., Armugam A., Jeyaseelan K. α-Neurotoxin gene expression in Naja sputatrix: identification of a silencer element in the promoter region. Arch. Biochem. Biophys. 2002; 404: 98–105
  • Ma D., Armugam A., Jeyaseelan K. Expression of cardiotoxin-2 gene. Cloning, characterization and deletion of the promoter. Eur. J. Biochem. 2001; 1844–1850
  • Moura-da-Silva A. M., Paine M. J., Diniz M. R., Theakston R. D., Crampton J. M. The molecular cloning of a phospholipase A2 from Bothrops jararacussu snake venom: evolution of venom group II phospholipase A2's may imply gene duplications. J. Mol. Evol. 1995; 41: 74–179
  • Nobuhisa I., Nakashima K., Deshimaru M., Ogawa T., Shimohigashi Y., Fukumaki Y., Sakaki Y., Hattori S., Kihara H., Ohno M. Accelerated evolution of Trimeresurus okinavensis venom gland phospholipase A2 isozymes genes. Gene 1996; 172: 267–272
  • Nokashima K., Nobuhisa I., Deshimaru M., Nakai M., Ogawa T., Shimohigashi Y., Fukumaki Y., Hottori M., Sakaki Y., Hattori S., Ohno M. Accelerated evolution in the protein-coding regions is universal in crotalinae snake venom gland phospholipase A2 isozyme genes. Proc. Natl. Acad. Sci. USA 1995; 92: 5605–5609
  • Ohno M., Chijiwa T., Oda-Ueda N., Ogawa T., Hattori S. Molecular evolution of myotoxic phospholipase A2 from snake venom. Toxicon 2002; 42: 841–854
  • Ohno M., Menez R., Ogawa T., Danse J. M., Shimohigashi Y., Fromen C., Ducancel F., Zinn-Justin S., Le Du M. H., Boulain J. C., Tamiya T., Menez A. Molecular evolution of snake toxins: is the functional diversity of snake toxins associated with a mechanism of accelerated evolution?. Prog. Nucleic Acid Res. Mol. Biol. 1998; 59: 307–364
  • Patthy L. Protein Evolution. Blackwell Science, Oxford 1999
  • Rosenberg P. Lethal potency of snake venom phospholipase A2 enzymes. Venom Phospholipase A2 Enzymes: Structure, Function and Mechanism, R. M. Kini. John Wiley & Sons, New York 1997a; 130–154
  • Rosenberg P. Pitfalls to avoid in the study of correlations between enzymatic activity and pharmacological properties of phospholipase A2 enzymes. Venom Phospholipase A2 Enzymes: Structure, Function and Mechanism, R. M. Kini. John Wiley & Sons, New York 1997b; 155–183
  • Scott D. L. Phospholipase A2: structure and catalytic properties. Venom Phospholipase A2 Enzymes: Structure, Function and Mechanism, R. M. Kini. John Wiley & Sons, New York 1997; 97–128
  • Sivaraman T., Kumar T. K.S., Jayaraman G., Han C. C., Yu C. Characterization of a partially structured state in an all-beta-sheet protein. Biochem. J. 1997; 321: 457–464
  • Sun Y. J., Wu W. G., Chiang C. M., Hsin A.Y., Hsiao C. D. Crystal structure of cardiotoxin V from Taiwan cobra venom: pH-dependent conformational change and a novel membrane-binding motif identified in the three-finger loops of P-type cardiotoxin. Biochemistry 1997; 36: 2403–2413
  • Tamiya T., Lamouroux A., Julien J. F., Grima B., Mallet J., Fromageot P., Menez A. Cloning and sequence analysis of the cDNA encoding a snake neurotoxin precursor. Biochimie 1985; 67: 185–189
  • Tsai I. H., Chen Y. H., Wang Y. M., Liau M. Y., Lu P. J. Differential expression and geographic variation of venom phospholipase A2 of Calloselasma rhodostoma and Trimeresurus mucrosquamatus. Arch. Biochem. Biophys. 2001; 387: 257–264
  • Tsetlin V. I. Snake venom α-neurotoxins and other “three-finger” proteins. Eur. J. Biochem. 1999; 264: 281–286
  • Wu P. F., Chang L. S. Genetic organization of A chain and B chain of β-bungarotoxin from Taiwan banded krait (Bungarus multicinctus). A chain genes and B chain genes do not share a common origin. Eur. J. Biochem. 2000; 267: 4668–4675
  • Yang C. C. Structure-function relationship of phospholipase A2 from snake venoms. J. Toxicol. 1994; 13: 125–177
  • Yang C. C. Chemical modification and functional sites of phospholipases A2. Venom Phospholipase A2 Enzymes: Structure, Function and Mechanism, R. M. Kini. John Wiley & Sons, New York 1997; 185–204
  • Yang C. C., Chang L.S. Biochemistry and molecular biology of snake neurotoxin. J. Chinese Chem. Soc. 1999; 46: 319–332

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