136
Views
6
CrossRef citations to date
0
Altmetric
Research Article

Experimental antivenoms from chickens and rabbits and their comparison with commercially available equine antivenom against the venoms of Daboia russelii and Echis carinatus snakes

, , , , , & show all
Pages 702-713 | Received 08 Mar 2020, Accepted 14 Apr 2020, Published online: 30 Apr 2020

References

  • Almeida, C.M.C., et al., 2008. Development of process to produce polyvalent IgY antibodies anti-African snake venom. Toxicon, 52, 293–301.
  • Araujo, A.S., et al., 2010. Brazilian IgY-Bothrops antivenom: studies on the development of a process in chicken egg yolk. Toxicon, 55, 739–744.
  • Bawaskar, H.S., and Bawaskar, P.H., 2019. Snakebite envenoming. The lancet, 393 (10167), 131.
  • Beghini, D.G., et al., 2008. Ability of rabbit antiserum against crotapotin to neutralize the neurotoxic, myotoxic and phospholipase A2 activities of crotoxin from Crotalus durissus cascavella snake venom. Toxicology in vitro, 22 (1), 240–248.
  • Bradford, M.M., 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical biochemistry, 72 (1–2), 248–254.
  • Camey, K.U., et al., 2002. Pharmacological characterization and neutralization of the venoms used in the production of Bothropic antivenom in Brazil. Toxicon, 40 (5), 501–509.
  • Choudhury, M., et al., 2017. Comparison of proteomic profiles of the venoms of two of the ‘Big Four’ snakes of India, the Indian cobra (Naja naja) and the common krait (Bungarus caeruleus), and analyses of their toxins. Toxicon, 135, 33–42.
  • da Rocha, D.G., et al., 2017. Development of IgY antibodies against anti-snake toxins endowed with highly lethal neutralizing activity. European journal of pharmaceutical sciences, 106, 404–412.
  • Duan, H.L., et al., 2016. Anti-Trimeresurus albolabris venom IgY antibodies: preparation, purification and neutralization efficacy. Journal of venomous animals and toxins including tropical diseases, 22 (1), 23.
  • Gutierrez, J.M., 2017. Antivenoms: life saving drugs for envenomings by animal bites and stings. Toxicon, 150, 11–12.
  • Joseph, J.K., et al., 2007. First authenticated cases of life-threatening envenoming by the hump-nosed pit viper (Hypnale hypnale) in India. Transactions of the royal society of tropical medicine & hygiene, 101 (1), 85–90.
  • Kalita, B., et al., 2018. Proteomic analysis reveals geographic variation in venom composition of Russell’s Viper in the Indian subcontinent: implications for clinical manifestations post-envenomation and antivenom treatment. Expert review of proteomics, 15 (10), 837–849.
  • Kiem, T.X., 2000. The production of Calloselasma rhodostoma antivenom (C.R.A.V.) from egg yolk of hens immunized with venom: its application for treatment of snake bite patients in Vietnam. In: Proceedings of the XIIIth World Congress of the International Society of Toxinology. Paris, France: International Society of Toxinology.
  • Laustsen, A.H., et al., 2018. Pros and cons of different therapeutic antibody formats for recombinant antivenom development. Toxicon, 146, 151–175.
  • Lee, W., et al., 2017. Insights into the chicken IgY with emphasis on the generation and applications of chicken recombinant monoclonal antibodies. Journal of immunological methods, 447, 71–78.
  • León, G., et al., 2000. Comparative study on the ability of IgG and Fab sheep antivenoms to neutralize local hemorrhage, edema and myonecrosis induced by Bothrops asper (terciopelo) snake venom. Toxicon, 38 (2), 233–244.
  • Liu, J., et al., 2017. Preparation and neutralization efficacy of IgY antibodies raised against Deinagkistrodon acutus venom. Journal of venomous animals and toxins including tropical diseases, 23 (1), 22.
  • Maya, D.C., et al., 2002. Development of viper-venom antibodies in chicken egg yolk and assay of their antigen binding capacity. Toxicon, 40, 857–861.
  • Meenatchisundaram, S., et al., 2008. Studies on pharmacological effects of Russell’s viper and Saw-scaled viper venom and its neutralization by chicken egg yolk antibodies. International immunopharmacology, 8 (8), 1067–1073.
  • Melo, L.L., et al., 2017. Cross-reactivity and inhibition myotoxic effects induced by Bothrops snake venoms using specific polyclonal anti-BnSP7 antibodies. Biologicals, 50, 109–116.
  • Navarro, D., et al., 2016. Development of a chicken-derived antivenom against the taipan snake (Oxyuranus scutellatus) venom and comparison with an equine antivenom. Toxicon, 120, 1–8.
  • Padula, A.M., and Winkel, K.D., 2016. Antivenom production in the alpaca (Vicugnapacos): physiological and antibody responses to monovalent and polyvalent immunization with Australian elapid venoms. Small ruminant research, 141, 63–69.
  • Padula, A.M., and Winkel, K.D., 2017. Antivenom production in the alpaca (Vicugnapacos): monovalent and polyvalent antivenom neutralisation of lethal and procoagulant toxins in Australian elapid venoms. Small ruminant research, 149, 34–39.
  • Patra, A., et al., 2017. Proteomics and antivenomics of Echis carinatus carinatus venom: correlation with pharmacological properties and pathophysiology of envenomation. Scientific reports, 7 (1), 17119.
  • Patrick Fernandez, G., et al., 2009. Neutralization of Bothrops mattogrossensis snake venom from Bolivia: experimental evaluation of llama and donkey antivenoms produced by caprylic acid precipitation. Toxicon, 55, 642–645.
  • Pawade, B. S., et al., 2016. Rapid and selective detection of experimental snake envenomation – use of gold nanoparticle based lateral flow assay. Toxicon, 119, 299–306.
  • Polson, A., et al., 1980. Isolation of viral IgY antibodies from yolks of immunized hens. Immunological communications, 9 (5), 475–493.
  • Prabhu, R.R., et al., 2010. Extraction and characterization of polyclonal egg yolk antibodies (IgY) in chicken against Cobra (Naja naja) venom. Current Science, 98 (2), 237–239.
  • Schade, R., et al., 2005. Chicken egg yolk antibodies (IgY -Technology): a review in progress in production and use in research and human and veterinary medicine. Alternatives to laboratory animals, 33 (2), 129–154.
  • Senji Laxme, R., et al., 2019. Beyond the ‘big four’: venom profiling of the medically important yet neglected Indian snakes reveals disturbing antivenom deficiencies. PLoS neglected tropical diseases, 13 (12), e0007899.
  • Shaikh, I.K., et al., 2017. Development of dot-ELISA for the detection of venoms of major Indian venomous snakes. Toxicon, 139, 66–73.
  • Sifi, A., et al., 2018. Development of a new approach of immunotherapy against scorpion envenoming: avian IgYs an alternative to equine IgGs. International immunopharmacology, 61, 256–265.
  • Tanaka, G.D., et al., 2016. Micrurus snake species: venom immunogenicity, antiserum cross reactivity and neutralization potential. Toxicon, 117, 59–68.
  • Tanwar, P.D., et al., 2017. Production and preclinical assessment of camelid immunoglobulins against Echis sochureki venom from desert of Rajasthan. Toxicon, 134, 1–5.
  • Venkatesan, C., et al., 2014. Neutralization of cobra venom by cocktail antiserum against venom proteins of cobra (Naja naja naja). Biologicals, 42 (1), 8–21.
  • Y-Neng Chiou, V., 2008. The development of IgY (ΔFc) antibody based neurotoxin antivenoms and the study on their neutralization efficacies. Clinical toxicology, 46 (6), 539–544.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.