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Research Articles

Lycopene mitigates arsenic-induced nephrotoxicity with activation of the Nrf2 pathway in mice

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Pages 446-456 | Received 16 Dec 2020, Accepted 14 Feb 2021, Published online: 02 Mar 2021

References

  • Aebi, H., 1984. Catalase in vitro. Methods in enzymology, 105, 121–126.
  • Al Olayan, E.M., et al., 2020. Protocatechuic acid mitigates cadmium-induced neurotoxicity in rats: role of oxidative stress, inflammation and apoptosis. The science of the total environment, 723, 137969.
  • Ali, M.M. and Agha, F.G., 2009. Amelioration of streptozotocin-induced diabetes mellitus, oxidative stress and dyslipidemia in rats by tomato extract lycopene. Scandinavian journal of clinical and laboratory investigation, 69 (3), 371–379.
  • Al-Megrin, W.A., et al., 2020. Nephroprotective effects of chlorogenic acid against sodium arsenite-induced oxidative stress, inflammation, and apoptosis. Journal of the science of food and agriculture, 100 (14), 5162–5170.
  • Atessahin, A., Ceribasi, A.O., and Yilmaz, S., 2007. Lycopene, a carotenoid, attenuates cyclosporine-induced renal dysfunction and oxidative stress in rats. Basic & clinical pharmacology & toxicology, 100 (6), 372–376.
  • Bayramoglu, A., Bayramoglu, G., and Senturk, H., 2013. Lycopene partially reverses symptoms of diabetes in rats with streptozotocin-induced diabetes. Journal of medicinal food, 16 (2), 128–132.
  • Boyacioglu, M., et al., 2016. The effects of lycopene on DNA damage and oxidative stress on indomethacin-induced gastric ulcer in rats. Clinical nutrition, 35 (2), 428–435.
  • Cavusoglu, K., et al., 2009. Protective effect of lycopene against mercury-induced cytotoxicity in albino mice: pathological evaluation. Journal of environmental biology, 30 (5), 807–814.
  • Clinton, S.K., 1998. Lycopene: chemistry, biology, and implications for human health and disease. Nutrition reviews, 56 (2), 35–51.
  • Cui, W., et al., 2017. Role of nuclear factor erythroid 2-related factor 2 in diabetic nephropathy. Journal of diabetes research, 2017, 3797802.
  • Di Mascio, P., Kaiser, S., and Sies, H., 1989. Lycopene as the most efficient biological carotenoid singlet oxygen quencher. Archives of biochemistry and biophysics, 274 (2), 532–538.
  • Dkhil, M.A., et al., 2020. Chlorogenic acid prevents hepatotoxicity in arsenic-treated mice: role of oxidative stress and apoptosis. Molecular biology reports, 47 (2), 1161–1171.
  • El-Gerbed, M.S., 2014. Protective effect of lycopene on deltamethrin-induced histological and ultrastructural changes in kidney tissue of rats. Toxicology and industrial health, 30 (2), 160–173.
  • El-Khadragy, M.F., et al., 2021. Chlorogenic acid abates male reproductive dysfunction in arsenic-exposed mice via attenuation of testicular oxido-inflammatory stress and apoptotic responses. Chemico-biological interactions, 333, 109333.
  • Ellman, G.L., 1959. Tissue sulfhydryl groups. Archives of biochemistry and biophysics, 82 (1), 70–77.
  • Factor, V.M., et al., 1998. Disruption of redox homeostasis in the transforming growth factor-alpha/c-myc transgenic mouse model of accelerated hepatocarcinogenesis. The journal of biological chemistry, 273 (25), 15846–15853.
  • Fouad, A.A., Al-Mulhim, A.S., and Jresat, I., 2012. Telmisartan treatment attenuates arsenic-induced hepatotoxicity in mice. Toxicology, 300 (3), 149–157.
  • Green, L.C., et al., 1982. Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. Analytical biochemistry, 126 (1), 131–138.
  • Hong, Y.S., Song, K.H., and Chung, J.Y., 2014. Health effects of chronic arsenic exposure. Journal of preventive medicine and public health, 47 (5), 245–252.
  • Hu, Y., et al., 2020. The role of reactive oxygen species in arsenic toxicity. Biomolecules, 10 (2), 240.
  • Huang, C., et al., 2019. Lycopene protects against t-BHP-induced neuronal oxidative damage and apoptosis via activation of the PI3K/Akt pathway. Molecular biology reports, 46 (3), 3387–3397.
  • Hughes, M.F., et al., 2011. Arsenic exposure and toxicology: a historical perspective. Toxicological sciences, 123 (2), 305–332.
  • Kapaj, S., et al., 2006. Human health effects from chronic arsenic poisoning–a review. Journal of environmental science and health, part A, 41 (10), 2399–2428.
  • Kaplan, S.A., 2005. Lycopene: modes of action to promote prostate health. The journal of urology, 174 (2), 679.
  • Karahan, I., et al., 2005. Protective effect of lycopene on gentamicin-induced oxidative stress and nephrotoxicity in rats. Toxicology, 215 (3), 198–204.
  • Li, X., et al., 2008. Urinary arsenic speciation and its correlation with 8-OHdG in Chinese residents exposed to arsenic through coal burning. Bulletin of environmental contamination and toxicology, 81 (4), 406–411.
  • Manikandan, R., et al., 2011. Ameliorative effects of curcumin against renal injuries mediated by inducible nitric oxide synthase and nuclear factor kappa B during gentamicin-induced toxicity in Wistar rats. European journal of pharmacology, 670 (2–3), 578–585.
  • Metwally, D.M., et al., 2020. Chlorogenic acid confers robust neuroprotection against arsenite toxicity in mice by reversing oxidative stress, inflammation, and apoptosis. Journal of functional foods, 75, 104202.
  • Mumtaz, F., et al., 2020. Exposure to arsenite and cadmium induces organotoxicity and miRNAs deregulation in male rats. Environmental science and pollution research international, 27 (14), 17184–17193.
  • Nezu, M. and Suzuki, N., 2020. Roles of Nrf2 in protecting the kidney from oxidative damage. International journal of molecular sciences, 21 (8), 2951.
  • Nurchi, V.M., et al., 2020. Arsenic toxicity: molecular targets and therapeutic agents. Biomolecules, 10 (2), 235.
  • Ohkawa, H., Ohishi, N., and Yagi, K., 1979. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Analytical biochemistry, 95 (2), 351–358.
  • Paglia, D.E. and Valentine, W.N., 1967. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. The journal of laboratory and clinical medicine, 70 (1), 158–169.
  • Palabiyik, S.S., et al., 2013. Protective effect of lycopene against ochratoxin A induced renal oxidative stress and apoptosis in rats. Experimental and toxicologic pathology, 65 (6), 853–861.
  • Pandir, D., Unal, B., and Bas, H., 2016. Lycopene protects the diabetic rat kidney against oxidative stress-mediated oxidative damage induced by furan. Brazilian archives of biology and technology, 59, e16150794.
  • Pfaffl, M.W., 2001. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic acids research, 29 (9), e45.
  • Prabhulkar, S. and Li, C.Z., 2010. Assessment of oxidative DNA damage and repair at single cellular level via real-time monitoring of 8-OHdG biomarker. Biosensors & bioelectronics, 26 (4), 1743–1749.
  • Prabu, S.M. and Muthumani, M., 2012. Silibinin ameliorates arsenic induced nephrotoxicity by abrogation of oxidative stress, inflammation and apoptosis in rats. Molecular biology reports, 39 (12), 11201–11216.
  • Ratnaike, R.N., 2003. Acute and chronic arsenic toxicity. Postgraduate medical journal, 79 (933), 391–396.
  • Robles-Osorio, M.L., Sabath-Silva, E., and Sabath, E., 2015. Arsenic-mediated nephrotoxicity. Renal failure, 37 (4), 542–547.
  • Rovero Costa, M., et al., 2019. Lycopene modulates pathophysiological processes of non-alcoholic fatty liver disease in obese rats. Antioxidants, 8 (8), 276.
  • Roy, A., Manna, P., and Sil, P.C., 2009. Prophylactic role of taurine on arsenic mediated oxidative renal dysfunction via MAPKs/ NF-kappaB and mitochondria dependent pathways. Free radical research, 43 (10), 995–1007.
  • Shalaby, A.M. and El Shaer, D.F., 2019. Lycopene protects against renal cortical damage induced by nandrolone decanoate in adult male rats. Annals of anatomy, 224, 142–152.
  • Sinha, M., Manna, P., and Sil, P.C., 2008. Arjunolic acid attenuates arsenic-induced nephrotoxicity. Pathophysiology, 15 (3), 147–156.
  • Sun, Y., Oberley, L.W., and Li, Y., 1988. A simple method for clinical assay of superoxide dismutase. Clinical chemistry, 34 (3), 497–500.
  • Tapiero, H., Townsend, D.M., and Tew, K.D., 2004. The role of carotenoids in the prevention of human pathologies. Biomedicine & pharmacotherapy, 58 (2), 100–110.
  • Tripathi, P., et al., 2019. Antioxidant therapy (lycopene and green tea extract) in periodontal disease: a promising paradigm. Journal of Indian Society of Periodontology, 23 (1), 25–30.
  • Vervaet, B.A., D’Haese, P.C., and Verhulst, A., 2017. Environmental toxin-induced acute kidney injury. Clinical kidney journal, 10 (6), 747–758.
  • Wang, H., et al., 2019. Inclusion complexes of lycopene and beta-cyclodextrin: preparation, characterization, stability and antioxidant activity. Antioxidants, 8 (8), 314.
  • Yilmaz, S., et al., 2006. Protective effect of lycopene on adriamycin-induced cardiotoxicity and nephrotoxicity. Toxicology, 218 (2–3), 164–171.
  • Yu, K., et al., 2018. Lycopene attenuates AFB1-induced renal injury with the activation of the Nrf2 antioxidant signaling pathway in mice. Food & function, 9 (12), 6427–6434.
  • Zeng, Y.C., et al., 2017. Protective effect and mechanism of lycopene on endothelial progenitor cells (EPCs) from type 2 diabetes mellitus rats. Biomedicine & pharmacotherapy, 92, 86–94.
  • Zhang, W., et al., 2014. Protective effect of resveratrol on arsenic trioxide-induced nephrotoxicity in rats. Nutrition research and practice, 8 (2), 220–226.
  • Zhao, Y., et al., 2020. Lycopene prevents DEHP-induced leydig cell damage with the Nrf2 antioxidant signaling pathway in mice. Journal of agricultural and food chemistry, 68 (7), 2031–2040.

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