2,219
Views
0
CrossRef citations to date
0
Altmetric
Review Article

Diagnostic and prognostic role of elafin in skin acute graft versus host disease: a systematic review

, , , , , , , , , & show all
Article: 2293497 | Received 20 Aug 2023, Accepted 02 Dec 2023, Published online: 19 Dec 2023

References

  • Ramachandran V, Kolli SS, Strowd LC. Review of graft-versus-host disease. Dermatol Clin. 2019;37(4):569–582. doi:10.1016/j.det.2019.05.014
  • Shantanam S. MUELLER. 乳鼠心肌提取 HHS public access. Physiol Behav. 2018;176(1):139–148.
  • Ferrara JL, Levine JE, Reddy P, et al. Graft-versus-host disease. Lancet. 2009;373(9674):1550–1561. doi:10.1016/S0140-6736(09)60237-3
  • Zewde MG, Morales G, Gandhi I, et al. Evaluation of elafin as a prognostic biomarker in acute graft-versus-host disease: M. G. Zewde et al. Transplant Cell Ther. 2021;27(12):988.e1–988.e7.
  • Lee SJ, Schubert MM. Graft-vs.-host disease. Crit Rev Oral Biol Med. 1997;8(2):201–216.
  • Levine JE, Logan BR, Wu J, et al. Acute graft-versus-host disease biomarkers measured during therapy can predict treatment outcomes: a blood and marrow transplant clinical trials network study. Blood. 2012;119(16):3854–3860. doi:10.1182/blood-2012-01-403063
  • Nagasawa M. Biomarkers of graft-vs-host disease: understanding and applications for the future. World J Transplant. 2021;11(8):335–343. doi:10.5500/wjt.v11.i8.335
  • Mahabal GD, George L, Peter D, et al. Utility of tissue elafin as an immunohistochemical marker for diagnosis of acute skin graft-versus-host disease: a pilot study. Clin Exp Dermatol. 2019;44(2):161–168. doi:10.1111/ced.13678
  • Van Bergen BH, Andriessen MPM, Spruijt KIJ, et al. Expression of SKALP/elafin during wound healing in human skin. Arch Dermatol Res. 1996;288(8):458–462. doi:10.1007/BF02505235
  • Alkemade HAC, van Vlijmen-Willems IMJJ, van Haelst UJGM, et al. Demonstration of skin-derived antileukoproteinase (skalp) and its target enzyme human leukocyte elastase in squamous cell carcinoma. J Pathol. 1994;174(2):121–129. doi:10.1002/path.1711740208
  • Chacon AH, Farooq U, Shiman MI, et al. Elafin: a possible new biomarker and immunohistochemical stain for pre-engraftment syndrome. J Am Acad Dermatol. 2013;69(2):e102–e103. doi:10.1016/j.jaad.2012.11.024
  • Paczesny S, Braun TM, Levine JE, et al. Elafin is a biomarker of graft-versus-host disease of the skin. Sci Transl Med. 2010;2(13):1–19.
  • Nomura S, Ishii K, Fujita S, et al. Associations between acute GVHD-related biomarkers and endothelial cell activation after allogeneic hematopoietic stem cell transplantation. Transpl Immunol. 2017;43–44(6):27–32.
  • Li X, Chen T, Gao Q, et al. A panel of 4 biomarkers for the early diagnosis and therapeutic efficacy of aGVHD. JCI Insight. 2019;4(16):e130413.
  • Metafuni E, Giammarco S, De Ritis DG, et al. Changes in protein serum levels during stem cell transplantation. Eur J Clin Invest. 2017;47(10):711–718. doi:10.1111/eci.12796
  • Nelson RP, Khawaja MR, Perkins SM, et al. Prognostic biomarkers for acute graft-versus-host disease risk after cyclophosphamide-fludarabine nonmyeloablative allotransplantation. Biol Blood Marrow Transplant. 2014;20(11):1861–1864. doi:10.1016/j.bbmt.2014.06.039
  • George L, Mahabal G, Mohanan E, et al. Limited utility of plasma elafin as a biomarker for skin graft-versus-host disease following allogeneic stem cell transplantation. Clin Exp Dermatol. 2021;46(8):1482–1487. doi:10.1111/ced.14785
  • Brüggen MC, Petzelbauer P, Greinix H, et al. Epidermal elafin expression is an indicator of poor prognosis in cutaneous graft-versus-host disease. J Invest Dermatol. 2015;135(4):999–1006. doi:10.1038/jid.2014.489
  • Wegner J, Weidenthaler-Barth B, Engelbert J, et al. Immunohistochemical markers for histopathological diagnosis and differentiation of acute cutaneous graft-versus-host disease. Exp Dermatol. 2021;30(12):1814–1819. doi:10.1111/exd.14416
  • Martin PJ, Schoch G, Fisher L, et al. A retrospective analysis of therapy for acute graft-versus-host disease: secondary treatment. Blood. 1991;77(8):1821–1828. doi:10.1182/blood.V77.8.1821.1821
  • Solán L, Carbonell D, Muñiz P, et al. Elafin as a predictive biomarker of acute skin graft-versus-host disease after haploidentical stem cell transplantation using post-transplant high-dose cyclophosphamide. Front Immunol. 2021;12(2):1–7.
  • Elgharib I, Khashaba SA, Elsaid HH, et al. Serum elafin as a potential inflammatory marker in psoriasis. Int J Dermatol. 2019;58(2):205–209. doi:10.1111/ijd.14217
  • Wang J, Ortiz C, Fontenot L, et al. High circulating elafin levels are associated with Crohn’s disease-associated intestinal strictures. PLoS One. 2020;15(4). doi:10.1371/journal.pone.0231083
  • Ollague JE, Nousari CH. Expression of elafin in dermatitis herpetiformis. Am J Dermatopathol. 2018;40(1):1–6. doi:10.1097/DAD.0000000000000915
  • Krawiec P, Pac-Kożuchowska E. Clinical significance of serum elafin in children with inflammatory bowel disease. Biomedicines. 2022;10(12):3267.
  • Solán L, Carbonell D, Muñiz P, et al. Elafin as a predictive biomarker of acute skin graft-versus-host disease after haploidentical stem cell transplantation using post-transplant high-dose cyclophosphamide. Front Immunol. 2021;12:516078.
  • Ali AM, DiPersio JF, Schroeder MA. The role of biomarkers in the diagnosis and risk stratification of acute graft-versus-host disease: a systematic review. Biol Blood Marrow Transplant. 2016;22(9):1552–1564. doi:10.1016/j.bbmt.2016.04.022