824
Views
1
CrossRef citations to date
0
Altmetric
Original Research

Lidocaine-loaded dissolving microneedle for safe local anesthesia on oral mucosa for dental procedure

, ORCID Icon, , , , , , , , , & show all
Pages 851-861 | Received 26 Jan 2023, Accepted 15 May 2023, Published online: 30 May 2023

References

  • Kaufman E, Epstein JB, Naveh E, et al. A survey of pain, pressure, and discomfort induced by commonly used oral local anesthesia injections. Anesth Prog. 2005;52(4):122–127. DOI:10.2344/0003-3006(2005)52[122:ASP]2.0.CO;2
  • St George G, Morgan A, Meechan J, et al. Injectable local anaesthetic agents for dental anaesthesia. Cochrane Database Systematic Rev. 2018;10(7): CD006487. DOI:10.1002/14651858.CD006487.pub2
  • Sisk AL. Long-acting local anesthetics in dentistry. Anesth Prog. 1992;39(3):53.
  • Meechan J. Effective topical anesthetic agents and techniques. Dental Clinics. 2002;46(4):759–766.
  • Eger EI, White PF, Bogetz MS. Clinical and economic factors important to anaesthetic choice for day-case surgery. Pharmacoeconomics. 2000;17(3):245–262.
  • Lee H-S. Recent advances in topical anesthesia. J Dent Anesth Pain Med. 2016;16(4):237–244.
  • Desai C, Wood FM, Schug SA, et al. Effectiveness of a topical local anaesthetic spray as analgesia for dressing changes: a double-blinded randomised pilot trial comparing an emulsion with an aqueous lidocaine formulation. Burns. 2014;40(1):106–112. DOI:10.1016/j.burns.2013.05.013
  • Das B, Nayak AK, Nanda U. Topical gels of lidocaine HCl using cashew gum and Carbopol 940: preparation and in vitro skin permeation. Int j biol macromol. 2013;62:514–517.
  • Ma Y, Tao W, Krebs SJ, et al. Vaccine Delivery to the Oral Cavity Using Coated Microneedles Induces Systemic and Mucosal Immunity. Pharm Res. 2014;2014(9):2393–2403. DOI:10.1007/s11095-014-1335-1
  • Santos SDC, Fávaro-Moreira NC, Abdalla HB, et al. A crossover clinical study to evaluate pain intensity from microneedle insertion in different parts of the oral cavity. Int J Pharmaceut. 2021;592:120050.
  • Lee B-M, Lee C, Lahiji SF, et al. Dissolving microneedles for rapid and painless local anesthesia. Pharmaceutics. 2020;12(4):366. DOI:10.3390/pharmaceutics12040366
  • Larrañeta E, McCrudden MT, Courtenay AJ, et al. Microneedles: a new frontier in nanomedicine delivery. Pharm Res. 2016;33(5):1055–1073. DOI:10.1007/s11095-016-1885-5
  • Yang H, Kim S, Kang G, et al. Centrifugal lithography: self‐shaping of polymer microstructures encapsulating biopharmaceutics by centrifuging polymer drops. Adv Healthcare Mater. 2017;6(19):1700326. DOI:10.1002/adhm.201700326
  • Nayak A, Das DB. Potential of biodegradable microneedles as a transdermal delivery vehicle for lidocaine. Biotechnol Lett. 2013;35(9):1351–1363.
  • Kochhar JS, Lim WXS, Zou S, et al. Microneedle integrated transdermal patch for fast onset and sustained delivery of lidocaine. Mol Pharmaceut. 2013;10(11):4272–4280. DOI:10.1021/mp400359w
  • Li X-J, Li Y, Meng Y, et al. Composite dissolvable microneedle patch for therapy of oral mucosal diseases. Biomater Sci. 2022;139:213001.
  • Kim Y-C, Park J-H, Prausnitz MR. Microneedles for drug and vaccine delivery. Adv Drug Delivery Rev. 2012;64(14):1547–1568.
  • Ingrole RS, Azizoglu E, Dul M, et al. Trends of microneedle technology in the scientific literature, patents, clinical trials and internet activity. Biomaterials. 2021;267:120491.
  • Yang H, Kang G, Jang M, et al. Development of lidocaine-loaded dissolving microneedle for rapid and efficient local anesthesia. Pharmaceutics. 2020;12(11):1067. DOI:10.3390/pharmaceutics12111067
  • Zhu T, Yu X, Yi X, et al. Lidocaine-loaded hyaluronic acid adhesive microneedle patch for oral mucosal topical anesthesia. Pharmaceutics. 2022;14(4):686. DOI:10.3390/pharmaceutics14040686
  • Lee S-Y, Wu C-L, Kuo L-K, et al. The effects of xylocaine spray for pain control caused by endotracheal tube in critical care. Int J Gerontol. 2012;6(1):11–15. DOI:10.1016/j.ijge.2011.09.018
  • Bruchim Y, Itay S, Shira BH, et al. Evaluation of lidocaine treatment on frequency of cardiac arrhythmias, acute kidney injury, and hospitalization time in dogs with gastric dilatation volvulus. J Vet Emerg Crit Care. 2012;22(4):419–427. DOI:10.1111/j.1476-4431.2012.00779.x
  • Larrañeta E, Moore J, Vicente-Pérez EM, et al. A proposed model membrane and test method for microneedle insertion studies. Int J Pharmaceut. 2014;472(1–2):65–73. DOI:10.1016/j.ijpharm.2014.05.042
  • Jang M, Baek S, Kang G, et al. Dissolving microneedle with high molecular weight hyaluronic acid to improve skin wrinkles, dermal density and elasticity. Int J Cosmet Sci. 2020;42(3):302–309. DOI:10.1111/ics.12617
  • Liu S, Jin M-N, Quan Y-S, et al. The development and characteristics of novel microneedle arrays fabricated from hyaluronic acid, and their application in the transdermal delivery of insulin. JControlled Release. 2021;161(3):933–941. DOI:10.1016/j.jconrel.2012.05.030
  • Wassdrop M, Krom BP, Bikker FJ, et al. The Bigger Picture: why Oral Mucosa Heals Better Than Skin. Biomolecules. 2021;11(8):1165. DOI:10.3390/biom11081165
  • Khalil H. A basic review on the inferior alveolar nerve block techniques. Anesth Essays And Res. 2014;8(1):3–8.
  • Min H, Kim Y, Nam J, et al. Shape of dissolving microneedles determines skin penetration ability and efficacy of drug delivery. Biomater Sci. 2023;145:213248.
  • Waghule T, Singhvi G, Dubey SK, et al. Microneedles: a smart approach and increasing potential for transdermal drug delivery system. Biomed Pharmacother. 2019;109:1249–1258.
  • Sarapultseva M, Sarapultsev A, Medvedeva S, et al. Structural damage to periodontal tissues at varying rate of anesthetic injection. J Dent Anesth Pain Med. 2018;18(2):89–95. DOI:10.17245/jdapm.2018.18.2.89

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.