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Review

A review of the protective effect of melatonin in pesticide-induced toxicity

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Pages 545-554 | Received 01 May 2016, Accepted 15 Jul 2016, Published online: 29 Jul 2016

References

  • Karami-Mohajeri S, Abdollahi M. Toxic influence of organophosphate, carbamate, and organochlorine pesticides on cellular metabolism of lipids, proteins, and carbohydrates: a systematic review. Hum Exp Toxicol. 2011;30(9):1119–1140.
  • Mostafalou S, Abdollahi M. Pesticides and human chronic diseases: evidences, mechanisms, and perspectives. Toxicol Appl Pharmacol. 2013;268(2):157–177.
  • Hodjat M, Rezvanfar MA, Abdollahi M. A systematic review on the role of environmental toxicants in stem cells aging. Food Chem Toxicol. 2015;86:298–308.
  • Maqbool F, Mostafalou S, Bahadar H, et al. Review of endocrine disorders associated with environmental toxicants and possible involved mechanisms. Life Sci. 2015;145:265–273.
  • Mokarizadeh A, Faryabi MR, Rezvanfar MA, et al. A comprehensive review of pesticides and the immune dysregulation: mechanisms, evidence and consequences. Toxicol Mech Meth. 2015;25(4):258–278.
  • Abdollahi M, Ranjbar A, Shadnia S, et al. Pesticides and oxidative stress: a review. Med Sci Monit. 2004;10(6):RA141–RA147.
  • Govender J, Loos B, Marais E, et al. Mitochondrial catastrophe during doxorubicin-induced cardiotoxicity: a review of the protective role of melatonin. J Pineal Res. 2014;57(4):367–380.
  • Mozaffari S, Abdollahi M. Melatonin, a promising supplement in inflammatory bowel disease: a comprehensive review of evidences. Curr Pharm Des. 2011;17(38):4372–4378.
  • Mozaffari S, Nikfar S, Abdollahi M. Metabolic and toxicological considerations for the latest drugs used to treat irritable bowel syndrome. Expert Opin Drug Metab Toxicol. 2013;9(4):403–421.
  • Manchester LC, Coto‐Montes A, Boga JA, et al. Melatonin: an ancient molecule that makes oxygen metabolically tolerable. J Pineal Res. 2015;59(4):403–419.
  • Ghayomi F, Navaei-Nigjeh M, Baeeri M, et al. A mechanistic approach for modulation of chlorpyrifos-induced toxicity in human lymphocytes by melatonin, coenzyme Q10, and vinpocetine. Hum Exp Toxicol. 2016;35(8):839-850.
  • Colovic MB, Krstic DZ, Lazarevic-Pasti TD, et al. Acetylcholinesterase inhibitors. Pharmacol Toxicol. 2013;11(3):315–335.
  • Ishii N, Senoo-Matsuda N, Miyake K, et al. Coenzyme Q10 can prolong C. elegans lifespan by lowering oxidative stress. Mech Ageing Dev. 2004;125(1):41–46.
  • Espino J, Bejarano I, Paredes SD, et al. Protective effect of melatonin against human leukocyte apoptosis induced by intracellular calcium overload: relation with its antioxidant actions. J Pineal Res. 2011;51(2):195–206.
  • Sidhu IP, Bhatti JS, Bhatti GK. Modulatory action of melatonin against chlorpyrifos induced hepatotoxicity in Wistar rats. AJMS. 2014;2(9):123–131.
  • Gultekin F, Patat S, Akca H, et al. Melatonin can suppress the cytotoxic effects of chlorpyrifos on human HepG2 cell lines. Hum Exp Toxicol. 2006;25(2):47–55.
  • Umosen AJ, Chidiebere U. Effect of melatonin on chlorpyrifos-induced alterations in reproductive hormones and semen characteristics in Wistar rats. AJPCT. 2012;2(6):742–753.
  • Umosen AJ, Ambali SF, Ayo JO, et al. Alleviating effects of melatonin on oxidative changes in the testes and pituitary glands evoked by subacute chlorpyrifos administration in Wistar rats. Asian Pac J Trop Biomed. 2012;2(8):645–650.
  • Heydary V, Navaei-Nigjeh M, Rahimifard M, et al. Biochemical and molecular evidences on the protection by magnesium oxide nanoparticles of chlorpyrifos-induced apoptosis in human lymphocytes. J Res Med Sci. 2015;20(11):1021–1031.
  • Karaoz E, Gultekin F, Akdogan M, et al. Protective role of melatonin and a combination of vitamin C and vitamin E on lung toxicity induced by chlorpyrifos-ethyl in rats. Exp Toxicol Pathol. 2002;54(2):97–108.
  • Buyukokuroglu ME, Cemek M, Yurumez Y, et al. Antioxidative role of melatonin in organophosphate toxicity in rats. Cell Biol Toxicol. 2008;24(2):151–158.
  • Cemek M, Büyükokuroğlu ME, Yürümez Y, et al. Tissue trace and major element levels in organophosphate insecticide fenthion (Lebaycid) toxicity in rats: prophylactic and therapeutic effect of exogenous melatonin. Ecotoxicol Environ Saf. 2010;73(2):206–212.
  • Fakhri-Bafghi MS, Ghasemi-Niri SF, Mostafalou S, et al. Protective effect of selenium-based medicines on toxicity of three common organophosphorus compounds in human erythrocytes in vitro. Cell J. 2016;17(4):740–747.
  • Karamian A, Shokrzadeh M, Ahmadi A. The potential chemoprotective effects of melatonin against genotoxicity induced by diazinon in human peripheral blood lymphocytes. Toxicol Ind Health. 2013;32(2):360–366.
  • Kamanyire R, Karalliedde L. Organophosphate toxicity and occupational exposure. Occup Med. 2004;54(2):69–75.
  • Barrett K, Jaward FM. A review of endosulfan, dichlorvos, diazinon, and diuron – pesticides used in Jamaica. Int J Environ Health Res. 2012;22(6):481–499.
  • Grover P, Danadevi K, Mahboob M, et al. Evaluation of genetic damage in workers employed in pesticide production utilizing the Comet assay. Mutagenesis. 2003;18(2):201–205.
  • Sarabia L, Maurer I, Bustos-Obregón E. Melatonin prevents damage elicited by the organophosphorous pesticide diazinon on mouse sperm DNA. Ecotoxicol Environ Saf. 2009;72(2):663–668.
  • Sarabia L, Maurer I, Bustos-Obregón E. Melatonin prevents damage elicited by the organophosphorous pesticide diazinon on the mouse testis. Ecotoxicol Environ Saf. 2009;72(3):938–942.
  • Sarabia L, Espinoza-Navarro O, Maurer I, et al. Protective effect of melatonin on damage in the sperm parameters of mice exposed to diazinon. Int J Morphol. 2011;29(4):1241–1247.
  • Jayasinghe SS. Effects of acute organophosphate ingestion on cognitive function, assessed with the mini mental state examination. J Postgrad Med. 2012;58(3):171.
  • Win-Shwe T, Nakajima D, Fujimaki H. Involvement of TLR4 in diazinon-induced neurotoxicity in mice. J Uoeh. 2012;34(1):1–13.
  • Ahmed MAE, Ahmed HI, El-Morsy EM. Melatonin protects against diazinon-induced neurobehavioral changes in rats. Neurochem Res. 2013;38(10):2227–2236.
  • Manzo L, Gregotti C, Di Nucci A, et al. Toxicology of paraquat and related bipyridyls: biochemical, clinical and therapeutic aspects. Vet Hum Toxicol. 1979;21(6):404–410.
  • Xu J, Sun S, Wei W, et al. Melatonin reduces mortality and oxidatively mediated hepatic and renal damage due to diquat treatment. J Pineal Res. 2007;42(2):166–171.
  • Winiarska K, Fraczyk T, Malinska D, et al. Melatonin attenuates diabetes‐induced oxidative stress in rabbits. J Pineal Res. 2006;40(2):168–176.
  • Reiter RJ, Tan D-X, Kim SJ, et al. Melatonin as a pharmacological agent against oxidative damage to lipids and DNA. Proc West Pharmacol Soc. 1998;41:229–236.
  • Moravčík R, Okuliarová M, Kováčová E, et al. Diquat-induced cytotoxicity on Vero and HeLa cell lines: effect of melatonin and dihydromelatonin. Interdiscip Toxicol. 2014;7(4):184–188.
  • Mussi MA, Calcaterra NB. Paraquat-induced oxidative stress response during amphibian early embryonic development. Comp Biochem Physiol C. 2010;151(2):240–247.
  • Hausburg MA, DeKrey GK, Salmen JJ, et al. Effects of paraquat on development of preimplantation embryos in vivo and in vitro. ‎Reprod Toxicol. 2005;20(2):239–246.
  • Bacchetta R, Mantecca P, Vailati G. Oocyte degeneration and altered ovipository activity induced by paraquat in the freshwater snail Physa fontinalis (Gastropoda: Pulmonata). J Mollusc Stud. 2002;68(2):181–186.
  • McCormack AL, Atienza JG, Johnston LC, et al. Role of oxidative stress in paraquat‐induced dopaminergic cell degeneration. ‎J Neurochem. 2005;93(4):1030–1037.
  • Gradinaru D, Minn A-L, Artur Y, et al. Effect of oxidative stress on UDP-glucuronosyltransferases in rat astrocytes. Toxicol Lett. 2012;213(3):316–324.
  • Pang YW, Sun YQ, Sun WJ, et al. Melatonin inhibits paraquat‐induced cell death in bovine preimplantation embryos. J Pineal Res. 2015;60(2):155–166.
  • Yamamoto H, Mohanan PV. Effects of melatonin on paraquat or ultraviolet light exposure‐induced DNA damage. J Pineal Res. 2001;31(4):308–313.
  • Choi S-I, Dadakhujaev S, Ryu H, et al. Melatonin protects against oxidative stress in granular corneal dystrophy type 2 corneal fibroblasts by mechanisms that involve membrane melatonin receptors. J Pineal Res. 2011;51(1):94–103.
  • Göcgeldi E, Uysal B, Korkmaz A, et al. Establishing the use of melatonin as an adjuvant therapeutic against paraquat-induced lung toxicity in rats. Exp Biol Med. 2008;233(9):1133–1141.
  • García JJ, López‐Pingarrón L, Almeida‐Souza P, et al. Protective effects of melatonin in reducing oxidative stress and in preserving the fluidity of biological membranes: a review. J Pineal Res. 2014;56(3):225–237.
  • Janda E, Parafati M, Aprigliano S, et al. The antidote effect of quinone oxidoreductase 2 inhibitor against paraquat‐induced toxicity in vitro and in vivo. Br J Pharmacol. 2013;168(1):46–59.
  • Singhal NK, Chauhan AK, Jain SK, et al. Silymarin- and melatonin-mediated changes in the expression of selected genes in pesticides-induced Parkinsonism. Mol Cell Biochem. 2013;384(1–2):47–58.
  • Sharma AK, Mehta AK, Rathor N, et al. Melatonin attenuates cognitive dysfunction and reduces neural oxidative stress induced by phosphamidon. Fundam Clin Pharmacol. 2013;27(2):146–151.
  • Smulders CJ, Bueters TJ, Van Kleef RG, et al. Selective effects of carbamate pesticides on rat neuronal nicotinic acetylcholine receptors and rat brain acetylcholinesterase. Toxicol Appl Pharmacol. 2003;193(2):139–146.
  • Maran E, Fernández M, Barbieri P, et al. Effects of four carbamate compounds on antioxidant parameters. Ecotoxicol Environ Saf. 2009;72(3):922–930.
  • Thiruchelvam M, Richfield EK, Baggs RB, et al. The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb: implications for Parkinson’s disease. J Neurosci. 2000;20(24):9207–9214.
  • Mayeux R. Epidemiology of neurodegeneration. Annu Rev Neurosci. 2003;26(1):81–104.
  • Ishido M. Melatonin inhibits maneb-induced aggregation of alpha-synuclein in rat pheochromocytoma cells. J Pineal Res. 2007;42(2):125–130.
  • Institóris L, Papp A, Siroki O, et al. Immuno- and neurotoxicological investigation of combined subacute exposure with the carbamate pesticide propoxur and cadmium in rats. Toxicology. 2002;178(2):161–173.
  • Suke SG, Kumar A, Ahmed RS, et al. Protective effect of melatonin against propoxur-induced oxidative stress and suppression of humoral immune response in rats. Indian J Exp Biol. 2006;44(4):312–315.
  • Mehta KD, Mehta AK, Halder S, et al. Protective effect of melatonin on propoxur-induced impairment of memory and oxidative stress in rats. Environ Toxicol. 2014;29(6):705–713.
  • Ackerman F. The economics of atrazine. Int J Occup Environ Med. 2007;13(4):437–445.
  • Singh M, Kaur P, Sandhir R, et al. Protective effects of vitamin E against atrazine-induced genotoxicity in rats. Mutat Res Genet Toxicol Environ Mutagen. 2008;654(2):145–149.
  • Bhatti JS, Sidhu IP, Bhatti GK. Ameliorative action of melatonin on oxidative damage induced by atrazine toxicity in rat erythrocytes. Mol Cell Biochem. 2011;353(2):139–149.
  • Sharma B, Rai DK, Rai PK, et al. Determination of erythrocyte fragility as a marker of pesticide-induced membrane oxidative damage. In: Armstrong D, editor. Advanced protocols in oxidative stress II. New York: Humana Press; 2010. p. 123–128.
  • Tesoriere L, D’Arpa D, Conti S, et al. Melatonin protects human red blood cells from oxidative hemolysis: new insights into the radical‐scavenging activity. J Pineal Res. 1999;27(2):95–105.
  • Sethunathan N, Megharaj M, Chen Z, et al. Persistence of endosulfan and endosulfan sulfate in soil as affected by moisture regime and organic matter addition. Bull Environ Contam Toxicol. 2002;68(5):725–731.
  • Omurtag GZ, Tozan A, Sehirli AO, et al. Melatonin protects against endosulfan-induced oxidative tissue damage in rats. J Pineal Res. 2008;44(4):432–438.
  • Banerjee B, Hussain Q. Effects of endosulfan on humoral and cell-mediated immune responses in rats. Bull Environ Contam Toxicol. 1987;38(3):435–441.
  • Naqvi SM, Vaishnavi C. Bioaccumulative potential and toxicity of endosulfan insecticide to non-target animals. Comp Biochem Physiol C Comp Pharmacol. 1993;105(3):347–361.
  • Hsu C-H, Chi B-C, Casida JE. Melatonin reduces phosphine-induced lipid and DNA oxidation in vitro and in vivo in rat brain. J Pineal Res. 2002;32(1):53–58.
  • Baghaei A, Solgi R, Jafari A, et al. Molecular and biochemical evidence on the protection of cardiomyocytes from phosphine-induced oxidative stress, mitochondrial dysfunction and apoptosis by acetyl-l-carnitine. Environ Toxicol Pharmacol. 2016;42:30–37.
  • Hsu CH, Chi BC, Liu MY, et al. Phosphine-induced oxidative damage in rats: role of glutathione. Toxicology. 2002;179(1):1–8.
  • Urata Y, Honma S, Goto S, et al. Melatonin induces γ-glutamylcysteine synthetase mediated by activator protein-1 in human vascular endothelial cells. Free Radic Biol Med. 1999;27(7):838–847.
  • Vollrath L. The pineal organ. Berlin: Springer; 1981.
  • Al-Omary F. Melatonin: comprehensive profile. Profiles Drug Subst Excip Relat Methodol. 2013;38:159–226.
  • Erdemli HK, Akyol S, Armutcu F, et al. Melatonin and caffeic acid phenethyl ester in the regulation of mitochondrial function and apoptosis: the basis for future medical approaches. Life Sci. 2016;148:305–312.
  • Touitou Y. Human aging and melatonin. Clinical relevance. Exp Geront. 2001;36(7):1083–1100.
  • Andersen L, Werner M, Rosenberg J, et al. A systematic review of peri‐operative melatonin. Anaesthesia. 2014;69(10):1163–1171.
  • Rivara S, Pala D, Bedini A, et al. Therapeutic uses of melatonin and melatonin derivatives: a patent review (2012–2014). Expert Opin Ther Pat. 2015;25(4):425–441.
  • Waldhauser F, Waldhauser M, Lieberman H, et al. Bioavailability of oral melatonin in humans. Neuroendocrinology. 1984;39(4):307–313.
  • Bellapart J, Roberts JA, Appadurai V, et al. Pharmacokinetics of a novel dosing regimen of oral melatonin in critically ill patients. Clin Chem Lab Med. 2015;54(3):467–472.
  • Guardiola-Lemaître B. Toxicology of melatonin. J Biol Rhythms. 1997;12(6):697–706.
  • Lane EA, Moss HB. Pharmacokinetics of melatonin in man: first pass hepatic metabolism. J Clin Endocrinol Metab. 1985;61(6):1214–1216.
  • Andersen LP, Werner MU, Rosenkilde MM, et al. Pharmacokinetics of oral and intravenous melatonin in healthy volunteers. BMC Pharmacol Toxicol. 2016;17(1):1–8.
  • Harpsøe NG, Andersen LPH, Gögenur I, et al. Clinical pharmacokinetics of melatonin: a systematic review. Eur J Clin Pharmacol. 2015;m71(8):m901–m909.
  • Härtter S, Grözinger M, Weigmann H, et al. Increased bioavailability of oral melatonin after fluvoxamine coadministration. Clin Pharmacol Ther. 2000;67(1):1–6.
  • Proietti S, Carlomagno G, Dinicola S, et al. Soft gel capsules improve melatonin’s bioavailability in humans. Expert Opin Drug Metab Toxicol. 2014;10(9):1193–1198.
  • Charão MF, Baierle M, Gauer B, et al. Protective effects of melatonin-loaded lipid-core nanocapsules on paraquat-induced cytotoxicity and genotoxicity in a pulmonary cell line. Mutat Res Genet Toxicol Environ Mutagen. 2015;784:1–9.
  • Charão MF, Souto C, Brucker N, et al. Caenorhabditis elegans as an alternative in vivo model to determine oral uptake, nanotoxicity, and efficacy of melatonin-loaded lipid-core nanocapsules on paraquat damage. Int J Nanomedicine. 2015;10:5093.
  • Gooneratne NS, Edwards AY, Zhou C, et al. Melatonin pharmacokinetics following two different oral surge‐sustained release doses in older adults. J Pineal Res. 2012;52(4):437–445.

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