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Expert Opinion on Drug Metabolism & Toxicology Volume 13, 2017 - Issue 1
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Letter to the Editor

Polymorphisms of genes related to metotrexate response and toxicity in high-grade osteosarcoma

Massimo SerraPharmacogenomics and Pharmacogenetics Research Unit, Laboratory of Experimental Oncology, Orthopaedic Rizzoli Institute, Bologna, ItalyCorrespondence[email protected]
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Claudia Maria HattingerPharmacogenomics and Pharmacogenetics Research Unit, Laboratory of Experimental Oncology, Orthopaedic Rizzoli Institute, Bologna, ItalyView further author information
Page 123 | Published online: 21 Nov 2016

References

  • Hattinger CM, Tavanti E, Fanelli M, et al. Pharmacogenomics of genes involved in antifolate drug response and toxicity in osteosarcoma. Expert Opin Drug Metab Toxicol. 2016. Forthcoming. DOI:10.1080/17425255.2017.1246532
  • Hattinger CM, Biason P, Iacoboni E, et al. Candidate germline polymorphisms of genes belonging to the pathways of four drugs used in osteosarcoma standard chemotherapy associated with risk, survival and toxicity in non-metastatic high-grade osteosarcoma. Oncotarget. 2016. Epub 2016 Aug 22. [Epub ahead of print]. DOI:10.18632/oncotarget.11486
  • Hegyi M, Arany A, Semsei AF, et al. Pharmacogenetic analysis of high-dose methotrexate treatment in children with osteosarcoma. Oncotarget. 2016. Epub 2016 Aug 23. [Epub ahead of print]. DOI:10.18632/oncotarget.11543
  • Kimchi-Sarfaty C, Gribar JJ, Gottesman MM. Functional characterization of coding polymorphisms in the human MDR1 gene using a vaccinia virus expression system. Mol Pharmacol. 2002;62:1–6. Epub 2002 Jun 18.

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