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Review

Mitral transcatheter edge-to-edge repair: patient selection, current devices, and clinical outcomes

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Pages 187-196 | Received 06 Sep 2023, Accepted 20 Dec 2023, Published online: 28 Dec 2023

References

  • Vahanian A, Beyersdorf F, Praz F, et al. 2021 ESC/EACTS guidelines for the management of valvular heart disease. Eur Heart J. 2022 Feb 12;43(7):561–632. doi: 10.1093/eurheartj/ehab395
  • Nkomo VT, Gardin JM, Skelton TN, et al. Burden of valvular heart diseases: a population-based study. Lancet. 2006 Sep 16;368(9540):1005–1011. doi: 10.1016/S0140-6736(06)69208-8
  • El Sabbagh A, Reddy YNV, Nishimura RA. Mitral valve regurgitation in the contemporary era: insights into diagnosis, management, and future directions. JACC Cardiovasc Imaging. 2018 Apr;11(4):628–643. doi: 10.1016/j.jcmg.2018.01.009
  • Raman J, Narang A, Appadurai V, et al. The increasing use of mitral transcatheter edge-to-edge repair in complex and high-risk patients. Heart Lung Circ. 2023 Jun;32(6):653–655.
  • Alfieri O, De Bonis M. The role of the edge-to-edge repair in the surgical treatment of mitral regurgitation. J Card Surg. 2010 Sep;25(5):536–541. doi: 10.1111/j.1540-8191.2010.01073.x
  • Feldman T, Wasserman HS, Herrmann HC, et al. Percutaneous mitral valve repair using the edge-to-edge technique: six-month results of the EVEREST Phase I Clinical Trial. J Am Coll Cardiol. 2005 Dec 6;46(11):2134–2140. doi: 10.1016/j.jacc.2005.07.065
  • Li CH, Arzamendi D, Carreras F. Role of Imaging Techniques in Percutaneous Treatment of Mitral Regurgitation. Rev Esp Cardiol (Engl Ed). 2016 Apr;69(4):421–436. doi: 10.1016/j.recesp.2015.12.009
  • Layoun H, Harb SC, Krishnaswamy A, et al. Patient selection for mitral transcatheter edge-to-edge repair. Methodist DeBakey Cardiovasc J. 2023;19(3):26–36. doi: 10.14797/mdcvj.1199
  • Mauri L, Garg P, Massaro JM, et al. The EVEREST II Trial: design and rationale for a randomized study of the evalve mitraclip system compared with mitral valve surgery for mitral regurgitation. Am Heart J. 2010 Jul;160(1):23–29.
  • Feldman T, Kar S, Elmariah S, et al. Randomized comparison of percutaneous repair and surgery for mitral regurgitation: 5-year results of EVEREST II. J Am Coll Cardiol. 2015 Dec 29;66(25):2844–2854. doi: 10.1016/j.jacc.2015.10.018
  • Stone GW, Lindenfeld J, Abraham WT, et al. Transcatheter Mitral-Valve Repair in patients with heart failure. N Engl J Med. 2018 Dec 13;379(24):2307–2318. doi: 10.1056/NEJMoa1806640
  • Obadia JF, Messika-Zeitoun D, Leurent G, et al. Percutaneous Repair or Medical Treatment for Secondary Mitral Regurgitation. N Engl J Med. 2018 Dec 13;379(24):2297–2306. doi: 10.1056/NEJMoa1805374
  • Pibarot P, Delgado V, Bax JJ. MITRA-FR vs. COAPT: lessons from two trials with diametrically opposed results. Eur Heart J Cardiovasc Imaging. 2019 Jun 1;20(6):620–624.
  • Grayburn PA, Sannino A, Packer M. Proportionate and disproportionate functional mitral regurgitation: a new conceptual framework that reconciles the results of the MITRA-FR and COAPT trials. JACC Cardiovasc Imaging. 2019 Feb;12(2):353–362. doi: 10.1016/j.jcmg.2018.11.006
  • Cruz-Gonzalez I, Estevez-Loureiro R, Barreiro-Perez M, et al. Mitral and tricuspid valve disease: diagnosis and management. Consensus document of the section on valvular heart disease and the cardiovascular imaging, clinical cardiology, and Interventional Cardiology Associations of the Spanish Society of Cardiology. Revista Española de Cardiología (English Edition). 2022 Aug 1;75(11):911–922. doi: 10.1016/j.rec.2022.05.031
  • Shah N, Madhavan MV, Gray WA, et al. Prediction of death or HF hospitalization in patients with severe FMR: the COAPT risk score. JACC: Cardiovasc Interv. 2022 Oct 10;15(19):1893–1905. doi: 10.1016/j.jcin.2022.08.005
  • Adamo M, Rubbio AP, Zaccone G, et al. Prediction of mortality and heart failure hospitalisations in patients undergoing M-TEER: external validation of the COAPT risk score. EuroIntervention. 2023 Apr 24;18(17):1408–1417. doi: 10.4244/EIJ-D-22-00992
  • Lim DS, Herrmann HC, Grayburn P, et al. Consensus document on non-suitability for transcatheter mitral valve repair by edge-to-edge therapy. Structural Heart. 2021 May 04;5(3):227–233. doi: 10.1080/24748706.2021.1902595
  • Rogers JH, Asch F, Sorajja P, et al. Expanding the spectrum of TEER suitability: evidence from the EXPAND G4 post approval study. JACC: Cardiovasc Interv. 2023 Jun 26;16(12):1474–1485. doi: 10.1016/j.jcin.2023.05.014
  • Hausleiter J, Lim DS, Gillam LD, et al. Transcatheter edge-to-edge repair in patients with anatomically complex degenerative mitral regurgitation. J Am Coll Cardiol. 2023 Feb 7;81(5):431–442. doi: 10.1016/j.jacc.2022.11.034
  • Chakravarty T, Makar M, Patel D, et al. Transcatheter edge-to-edge mitral valve repair with the MitraClip G4 system. JACC: Cardiovasc Interv. 2020 Oct 26;13(20):2402–2414. doi: 10.1016/j.jcin.2020.06.053
  • Stolz L, Braun D, Higuchi S, et al. Transcatheter edge-to-edge mitral valve repair in mitral regurgitation: current status and future prospects. Expert Rev Med Devices. 2023 Feb;20(2):99–108.
  • Hausleiter J, Stocker TJ, Adamo M, et al. Mitral valve transcatheter edge-to-edge repair. EuroIntervention. 2023 Jan 23;18(12):957–976. doi: 10.4244/EIJ-D-22-00725
  • Feldman T, Foster E, Glower DD, et al. Percutaneous repair or surgery for mitral regurgitation. N Engl J Med. 2011 Apr 14;364(15):1395–1406. doi: 10.1056/NEJMoa1009355
  • Otto CM, Nishimura RA, Bonow RO, et al. ACC/AHA guideline for the management of patients with valvular heart disease: executive summary: a report of the American College of Cardiology/American Heart Association Joint Committee on clinical practice guidelines. Circulation. 2021 Feb 2;143(5):e35–e71.
  • Stone GW, Abraham WT, Lindenfeld J, et al. Five-year follow-up after transcatheter repair of secondary mitral regurgitation. N Engl J Med. 2023 Jun 1;388(22):2037–2048. doi: 10.1056/NEJMoa2300213
  • Iung B, Armoiry X, Vahanian A, et al. Percutaneous repair or medical treatment for secondary mitral regurgitation: outcomes at 2 years. Eur J Heart Fail. 2019 Dec;21(12):1619–1627.
  • Spargias K, Lim DS, Makkar R, et al. Three-year outcomes for transcatheter repair in patients with mitral regurgitation from the CLASP study. Catheter Cardiovasc Interv. 2023 Jul;102(1):145–154. doi: 10.1002/ccd.30686
  • Lim DS, Smith RL, Gillam LD, et al. Randomized comparison of transcatheter edge-to-edge repair for degenerative mitral regurgitation in prohibitive surgical risk patients. JACC: Cardiovasc Interv. 2022 Dec 26;15(24):2523–2536. doi: 10.1016/j.jcin.2022.09.005
  • Maisano F, Franzen O, Baldus S, et al. Percutaneous mitral valve interventions in the real world: early and 1-year results from the ACCESS-EU, a prospective, multicenter, nonrandomized post-approval study of the MitraClip therapy in Europe. J Am Coll Cardiol. 2013 Sep 17;62(12):1052–1061. doi: 10.1016/j.jacc.2013.02.094
  • Nickenig G, Estevez-Loureiro R, Franzen O, et al. Percutaneous mitral valve edge-to-edge repair: in-hospital results and 1-year follow-up of 628 patients of the 2011-2012 Pilot European Sentinel Registry. J Am Coll Cardiol. 2014 Sep 2;64(9):875–884. doi: 10.1016/j.jacc.2014.06.1166
  • Puls M, Lubos E, Boekstegers P, et al. One-year outcomes and predictors of mortality after MitraClip therapy in contemporary clinical practice: results from the German transcatheter mitral valve interventions registry. Eur Heart J. 2016 Feb 21;37(8):703–712. doi: 10.1093/eurheartj/ehv627
  • Pascual I, Arzamendi D, Carrasco-Chinchilla F, et al. Transcatheter mitral repair according to the cause of mitral regurgitation: real-life data from the Spanish MitraClip registry. Rev Esp Cardiol (Engl Ed). 2020 Aug;73(8):643–651.
  • von Bardeleben RS, Rogers JH, Mahoney P, et al. Real-world outcomes of fourth-generation mitral transcatheter repair: 30-day results from EXPAND G4. JACC: Cardiovasc Interv. 2023 Jun 26;16(12):1463–1473. doi: 10.1016/j.jcin.2023.05.013
  • Mauri V, Besler C, Riebisch M, et al. German multicenter experience with a new leaflet-based transcatheter mitral valve repair system for mitral regurgitation. JACC: Cardiovasc Interv. 2020 Dec 14;13(23):2769–2778. doi: 10.1016/j.jcin.2020.08.025
  • Li CP, Estevez-Loureiro R, Freixa X, et al. Iberian experience with PASCAL transcatheter edge-to-edge repair for mitral valve regurgitation. Rev Esp Cardiol (Engl Ed). 2023 Jan;76(1):25–31.
  • Schneider L, Markovic S, Mueller K, et al. Mitral valve transcatheter edge-to-edge repair using MitraClip or PASCAL: a multicenter propensity score-matched comparison. JACC: Cardiovasc Interv. 2022 Dec 26;15(24):2554–2567. doi: 10.1016/j.jcin.2022.10.028
  • Luedike P, Riebisch M, Schindhelm F, et al. Impact of mitral valve repair technologies on predictability of post-delivery residual mitral regurgitation. JACC: Cardiovasc Interv. 2021 Dec 13;14(23):2638–2640. doi: 10.1016/j.jcin.2021.09.024
  • Kar S, Feldman T, Qasim A, et al. Five-year outcomes of transcatheter reduction of significant mitral regurgitation in high-surgical-risk patients. Heart. 2019 Nov;105(21):1622–1628.
  • Wang TKM, Chatfield A, Wang MTM, et al. Comparison of percutaneous MitraClip versus mitral valve surgery for severe mitral regurgitation: a meta-analysis: mitraclip and mitral valve surgery meta-analysis. AsiaIntervention. 2020 Dec;6(2):77–84.
  • Agricola E, Oppizzi M, Pisani M, et al. Ischemic mitral regurgitation: mechanisms and echocardiographic classification. Eur J Echocardiogr. 2007 Mar;9(2):207–221.
  • Estevez-Loureiro R, Tavares Da Silva M, Baz-Alonso JA, et al. Percutaneous mitral valve repair in patients developing severe mitral regurgitation early after an acute myocardial infarction: a review. Front Cardiovasc Med. 2022;9:987122. doi: 10.3389/fcvm.2022.987122
  • Estevez-Loureiro R, Adamo M, Arzamendi D, et al. Transcatheter mitral valve repair in patients with acute myocardial infarction: insights from the European registry of MitraClip in acute mitral regurgitation following an acute myocardial infarction (EREMMI). EuroIntervention. 2020 Feb 20;15(14):1248–1250. doi: 10.4244/EIJ-D-19-00653
  • Estevez-Loureiro R, Shuvy M, Taramasso M, et al. Use of MitraClip for mitral valve repair in patients with acute mitral regurgitation following acute myocardial infarction: effect of cardiogenic shock on outcomes (IREMMI registry). Catheter Cardiovasc Interv. 2021 May 1;97(6):1259–1267. doi: 10.1002/ccd.29552
  • Haberman D, Estevez-Loureiro R, Benito-Gonzalez T, et al. Conservative, surgical, and percutaneous treatment for mitral regurgitation shortly after acute myocardial infarction. Eur Heart J. 2022 Feb 12;43(7):641–650. doi: 10.1093/eurheartj/ehab496
  • Tang GHL, Estevez-Loureiro R, Yu Y, et al. Survival following edge-to-edge transcatheter mitral valve repair in patients with cardiogenic shock: a nationwide analysis. J Am Heart Assoc. 2021 Apr 20;10(8):e019882. doi: 10.1161/JAHA.120.019882
  • Simard T, Vemulapalli S, Jung RG, et al. Transcatheter edge-to-edge mitral valve repair in patients with severe mitral regurgitation and cardiogenic shock. J Am Coll Cardiol. 2022 Nov 29;80(22):2072–2084. doi: 10.1016/j.jacc.2022.09.006
  • Chan V, Messika-Zeitoun D, Labinaz M, et al. Percutaneous mitral repair as salvage therapy in patients with mitral regurgitation and refractory cardiogenic shock. Circ Cardiovasc Interv. 2019 Nov;12(11):e008435.
  • Cheng R, Dawkins S, Hamilton MA, et al. Percutaneous mitral repair for patients in cardiogenic shock requiring inotropes and temporary mechanical circulatory support. JACC: Cardiovasc Interv. 2019 Dec 9;12(23):2440–2441. doi: 10.1016/j.jcin.2019.05.042
  • Falasconi G, Melillo F, Pannone L, et al. Use of edge-to-edge percutaneous mitral valve repair for severe mitral regurgitation in cardiogenic shock: A multicenter observational experience (MITRA-SHOCK study). Catheter Cardiovasc Interv. 2021 Jul 1;98(1):E163–E170. doi: 10.1002/ccd.29683
  • Jung RG, Simard T, Kovach C, et al. Transcatheter mitral valve repair in cardiogenic shock and mitral regurgitation: a patient-level, multicenter analysis. JACC: Cardiovasc Interv. 2021 Jan 11;14(1):1–11. doi: 10.1016/j.jcin.2020.08.037
  • Saran N, Greason KL, Schaff HV, et al. Does Mitral Valve Calcium in Patients Undergoing Mitral Valve Replacement Portend Worse Survival? Ann Thorac Surg. 2019 Feb;107(2):444–452.
  • Cheng R, Tat E, Siegel RJ, et al. Mitral annular calcification is not associated with decreased procedural success, durability of repair, or left ventricular remodelling in percutaneous edge-to-edge repair of mitral regurgitation. EuroIntervention. 2016 Oct 20;12(9):1176–1184. doi: 10.4244/EIJV12I9A191
  • Fernandez-Peregrina E, Pascual I, Freixa X, et al. Transcatheter edge-to-edge mitral valve repair in patients with mitral annulus calcification. EuroIntervention. 2022 Mar 18;17(16):1300–1309. doi: 10.4244/EIJ-D-21-00205
  • Niikura H, Gossl M, Kshettry V, et al. Causes and clinical outcomes of patients who are ineligible for transcatheter mitral valve replacement. JACC: Cardiovasc Interv. 2019 Jan 28;12(2):196–204. doi: 10.1016/j.jcin.2018.10.042
  • Ludwig S, Sedighian R, Weimann J, et al. Management of patients with mitral regurgitation ineligible for standard therapy undergoing TMVI screening. EuroIntervention. 2022 Jun 24;18(3):213–223. doi: 10.4244/EIJ-D-21-00708

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