Right heart failure after durable left ventricular assist device implantation

References

• Mehra MR, Goldstein DJ, Cleveland JC, et al. Five-year outcomes in patients with fully magnetically levitated vs axial-flow left ventricular assist devices in the MOMENTUM 3 randomized trial. JAMA. 2022;328(12):1233–1242. doi: 10.1001/jama.2022.16197
   PubMed Web of Science ®Google Scholar
• Uriel N, Colombo PC, Cleveland JC, et al. Hemocompatibility-related outcomes in the momentum 3 trial at 6 months. Circulation. 2017;135(21):2003–2012. doi: 10.1161/CIRCULATIONAHA.117.028303
   PubMed Web of Science ®Google Scholar
• Mehra MR, Uriel N, Naka Y, et al. A fully magnetically levitated left ventricular assist device — final report. N Engl J Med. 2019;380(17):1618–1627. doi: 10.1056/NEJMoa1900486
   PubMed Web of Science ®Google Scholar
• Rose EA, Gelijns AC, Moskowitz AJ, et al. Long-term use of a left ventricular assist device for end-stage heart failure. N Engl J Med. 2001;345(20):1435–1443. doi: 10.1056/NEJMoa012175
   PubMed Web of Science ®Google Scholar
• Heatley G, Sood P, Goldstein D, et al. Clinical trial design and rationale of the multicenter study of MagLev technology in patients undergoing mechanical circulatory support therapy with HeartMate 3 (MOMENTUM 3) investigational device exemption clinical study protocol. J Heart Lung Transplant. 2016;35(4):528–536. doi: 10.1016/j.healun.2016.01.021
   PubMed Web of Science ®Google Scholar
• Eisen HJ. Left ventricular assist devices (LVADS): history, clinical application and complications. Korean Circ J. 2019 Jul;49(7):568–585. doi: 10.4070/kcj.2019.0161
   PubMed Web of Science ®Google Scholar
• Miller T, Topkara VK. Mechanical circulatory support device selection for bridging to cardiac transplantation: a clinical guide. Expert Rev Med Devices. 2023;20(6):1–9. doi: 10.1080/17434440.2023.2206562
   PubMed Web of Science ®Google Scholar
• Mullan CW, Chouairi F, Sen S, et al. Changes in use of left ventricular assist devices as bridge to transplantation with new heart allocation policy. JACC Heart Fail. 2021 Jun 01;9(6):420–429. doi: 10.1016/j.jchf.2021.01.010
   PubMed Web of Science ®Google Scholar
• Uriel MH, Clerkin KJ, Takeda K, et al. Bridging to transplant with HeartMate 3 left ventricular assist devices in the new heart organ allocation system: an individualized approach. J Heart Lung Transplant. 2022 Sep 10;42(1):124–133. doi: 10.1016/j.healun.2022.08.022
   PubMed Web of Science ®Google Scholar
• Goldstein DJ, Naka Y, Horstmanshof D, et al. Association of clinical outcomes with left ventricular assist device use by bridge to transplant or destination therapy intent: the multicenter study of MagLev technology in patients undergoing mechanical circulatory support therapy with HeartMate 3 (MOMENTUM 3) randomized clinical trial. JAMA Cardiol. 2020;5(4):411–419. doi: 10.1001/jamacardio.2019.5323
   PubMed Web of Science ®Google Scholar
• Teuteberg JJ, Stewart GC, Jessup M, et al. Implant strategies change over time and impact outcomes: insights from the INTERMACS (interagency registry for mechanically assisted circulatory support). JACC Heart Fail. 2013 Oct 01;1(5):369–378. doi: 10.1016/j.jchf.2013.05.006
   PubMedGoogle Scholar
• Topkara VK, Garan AR, Fine B, et al. Myocardial recovery in patients receiving contemporary left ventricular assist devices: results from the interagency registry for mechanically assisted circulatory support (INTERMACS). Circ Heart Fail. 2016 Jul;9(7). doi: 10.1161/CIRCHEARTFAILURE.116.003157
   Web of Science ®Google Scholar
• Birks EJ, George RS, Firouzi A, et al. Long-term outcomes of patients bridged to recovery versus patients bridged to transplantation. J Thorac Cardiovasc Surg. 2012;144(1):190–196. doi: 10.1016/j.jtcvs.2012.03.021
   PubMed Web of Science ®Google Scholar
• Houston BA, Brittain EL, Tedford RJ, et al. Right ventricular failure. N Engl J Med. 2023;388(12):1111–1125. doi: 10.1056/NEJMra2207410
   PubMed Web of Science ®Google Scholar
• Hall SA, Copeland H, Alam A, et al. The “right” definition for post-left ventricular assist device right heart failure: the more we learn, the less we know. Front Cardiovasc Med. 2022;9:893327. doi: 10.3389/fcvm.2022.893327
   PubMed Web of Science ®Google Scholar
• Kormos RL, Antonides CFJ, Goldstein DJ, et al. Updated definitions of adverse events for trials and registries of mechanical circulatory support: a consensus statement of the mechanical circulatory support academic research consortium. J Heart Lung Transplant. 2020;39(8):735–750. doi: 10.1016/j.healun.2020.03.010
   PubMed Web of Science ®Google Scholar
• Sack KL, Dabiri Y, Franz T, et al. Investigating the role of interventricular interdependence in development of right heart dysfunction during LVAD support: a patient-specific methods-based approach. Front Physiol. 2018;9:520. doi: 10.3389/fphys.2018.00520
   PubMed Web of Science ®Google Scholar
• Brener MI, Masoumi A, Ng VG, et al. Invasive right ventricular pressure-volume analysis: basic principles, clinical applications, and practical recommendations. Circ Heart Fail. 2022;15(1):e009101. doi: 10.1161/CIRCHEARTFAILURE.121.009101
   PubMed Web of Science ®Google Scholar
• Wang Y, Loghmanpour N, Vandenberghe S, et al. Simulation of dilated heart failure with continuous flow circulatory support. PLoS One. 2014;9(1):e85234. doi: 10.1371/journal.pone.0085234
   PubMed Web of Science ®Google Scholar
• Park JIK, Heikhmakhtiar AK, Kim CH, et al. The effect of heart failure and left ventricular assist device treatment on right ventricular mechanics: a computational study. Biomed Eng Online. 2018 May 22;17(1):62. doi: 10.1186/s12938-018-0498-0
   PubMedGoogle Scholar
• Uriel N, Sayer G, Addetia K, et al. Hemodynamic ramp tests in patients with left ventricular assist devices. JACC Heart Fail. 2016 Mar 1;4(3):208–217. doi: 10.1016/j.jchf.2015.10.001
   PubMed Web of Science ®Google Scholar
• Dang NC, Topkara VK, Mercando M, et al. Right heart failure after left ventricular assist device implantation in patients with chronic congestive heart failure. J Heart Lung Transplant. 2006;25(1):1–6. doi: 10.1016/j.healun.2005.07.008
   PubMed Web of Science ®Google Scholar
• Rame JE, Pagani FD, Kiernan MS, et al. Evolution of late right heart failure with left ventricular assist devices and association with outcomes. J Am Coll Cardiol. 2021 Dec 7;78(23):2294–2308. doi: 10.1016/j.jacc.2021.09.1362
   PubMed Web of Science ®Google Scholar
• Lo Coco V, De Piero ME, Massimi G, et al. Right ventricular failure after left ventricular assist device implantation: a review of the literature. J Thorac Dis. 2021 Feb;13(2):1256–1269.
   PubMed Web of Science ®Google Scholar
• Rajapreyar I, Soliman O, Brailovsky Y, et al. Late right heart failure after left ventricular assist device implantation: contemporary insights and future perspectives. JACC Heart Fail. 2023 Aug 1;11(8, Part 1):865–878. doi: 10.1016/j.jchf.2023.04.014
   PubMed Web of Science ®Google Scholar
• Rich JD, Gosev I, Patel CB, et al. The incidence, risk factors, and outcomes associated with late right-sided heart failure in patients supported with an axial-flow left ventricular assist device. J Heart Lung Transplant. 2017;36(1):50–58. doi: 10.1016/j.healun.2016.08.010
   PubMed Web of Science ®Google Scholar
• Frankfurter C, Molinero M, Vishram-Nielsen JKK, et al. Predicting the risk of right ventricular failure in patients undergoing left ventricular assist device implantation. Circ Heart Fail. 2020;13(10):e006994. doi: 10.1161/CIRCHEARTFAILURE.120.006994
   PubMed Web of Science ®Google Scholar
• Soliman OII, Akin S, Muslem R, et al. Derivation and validation of a novel right-sided heart failure Model after implantation of continuous flow left ventricular assist devices. Circulation. 2018;137(9):891–906. doi: 10.1161/CIRCULATIONAHA.117.030543
   PubMed Web of Science ®Google Scholar
• Matthews JC, Koelling TM, Pagani FD, et al. The right ventricular failure risk score: a preoperative tool for assessing the risk of right ventricular failure in left ventricular assist device candidates. J Am Coll Cardiol. 2008 Jun 3;51(22):2163–2172. doi: 10.1016/j.jacc.2008.03.009
   PubMed Web of Science ®Google Scholar
• Fitzpatrick JR 3rd, Frederick JR, Hsu VM, et al. Risk score derived from preoperative data analysis predicts the need for biventricular mechanical circulatory support. J Heart Lung Transplant. 2008 Dec;27(12):1286–1292.
   PubMed Web of Science ®Google Scholar
• Drakos SG, Janicki L, Horne BD, et al. Risk factors predictive of right ventricular failure after left ventricular assist device implantation. Am J Cardiol. 2010;105(7):1030–1035. doi: 10.1016/j.amjcard.2009.11.026
   PubMed Web of Science ®Google Scholar
• Kormos RL, Teuteberg JJ, Pagani FD, et al. Right ventricular failure in patients with the HeartMate II continuous-flow left ventricular assist device: incidence, risk factors, and effect on outcomes. J Thorac Cardiovasc Surg. 2010;139(5):1316–1324. doi: 10.1016/j.jtcvs.2009.11.020
   PubMed Web of Science ®Google Scholar
• Wang Y, Simon MA, Bonde P, et al. Decision tree for adjuvant right ventricular support in patients receiving a left ventricular assist device. J Heart Lung Transplant. 2012 Feb;31(2):140–149.
   PubMed Web of Science ®Google Scholar
• Atluri P, Goldstone AB, Fairman AS, et al. Predicting right ventricular failure in the modern, continuous flow left ventricular assist device era. Ann Thorac Surg. 2013 Sep;96(3):857–863; discussion 863-4. doi: 10.1016/j.athoracsur.2013.03.099
   PubMed Web of Science ®Google Scholar
• Kapelios CJ, Lund LH, Wever-Pinzon O, et al. Right heart failure following left ventricular device implantation: natural history, risk factors, and outcomes: an analysis of the STS INTERMACS database. Circ Heart Fail. 2022;15(6):e008706. doi: 10.1161/CIRCHEARTFAILURE.121.008706
   PubMed Web of Science ®Google Scholar
• Read JM, Azih NI, Peters CJ, et al. Hemodynamic reserve predicts early right heart failure after LVAD implantation. J Heart Lung Transplant. 2022;41(12):1716–1726. doi: 10.1016/j.healun.2022.07.003
   PubMed Web of Science ®Google Scholar
• Alkhunaizi FA, Azih NI, Read JM, et al. Characteristics and predictors of late right heart failure after left ventricular assist device implantation. ASAIO J. 2023;69(3):315–323. doi: 10.1097/MAT.0000000000001804
   PubMed Web of Science ®Google Scholar
• Bahl A, Qureshi B, Zhang K, et al. Explainable machine learning analysis of right heart failure after left ventricular assist device implantation. ASAIO J. 2023;69(5):417–423. doi: 10.1097/MAT.0000000000001843
   PubMed Web of Science ®Google Scholar
• Shad R, Quach N, Fong R, et al. Predicting post-operative right ventricular failure using video-based deep learning. Nat Commun. 2021 Aug 31;12(1):5192. doi: 10.1038/s41467-021-25503-9
   PubMed Web of Science ®Google Scholar
• Kato TS, Chokshi A, Singh P, et al. Markers of extracellular matrix turnover and the development of right ventricular failure after ventricular assist device implantation in patients with advanced heart failure. J Heart Lung Transplant. 2012;31(1):37–45. doi: 10.1016/j.healun.2011.10.007
   PubMed Web of Science ®Google Scholar
• Pinsino A, Mondellini GM, Royzman EA, et al. Cystatin C- versus creatinine-based assessment of renal function and prediction of early outcomes among patients with a left ventricular assist device. Circ Heart Fail. 2020;13(1):e006326. doi: 10.1161/CIRCHEARTFAILURE.119.006326
   PubMed Web of Science ®Google Scholar
• Feldman D, Pamboukian SV, Teuteberg JJ, et al. The 2013 international society for heart and lung transplantation guidelines for mechanical circulatory support: executive summary. J Heart Lung Transplant. 2013;32(2):157–187. doi: 10.1016/j.healun.2012.09.013
   PubMed Web of Science ®Google Scholar
• Anderson MB, Goldstein J, Milano C, et al. Benefits of a novel percutaneous ventricular assist device for right heart failure: the prospective recover right study of the impella RP device. J Heart Lung Transplant. 2015;34(12):1549–1560. doi: 10.1016/j.healun.2015.08.018
   PubMed Web of Science ®Google Scholar
• Costanzo MR, Saltzberg M, O’Sullivan J, et al. Early ultrafiltration in patients with decompensated heart failure and diuretic resistance. J Am Coll Cardiol. 2005 Dec 06;46(11):2047–2051. doi: 10.1016/j.jacc.2005.05.099
   PubMed Web of Science ®Google Scholar
• Bart BA, Goldsmith SR, Lee KL, et al. Ultrafiltration in decompensated heart failure with cardiorenal syndrome. N Engl J Med. 2012;367(24):2296–2304. doi: 10.1056/NEJMoa1210357
   PubMed Web of Science ®Google Scholar
• Haddad F, Hunt SA, Rosenthal DN, et al. Right Ventricular Function in Cardiovascular Disease, Part I. Circulation. 2008;117(11):1436–1448. doi: 10.1161/CIRCULATIONAHA.107.653576
   PubMed Web of Science ®Google Scholar
• Kukucka M, Potapov E, Stepanenko A, et al. Acute impact of left ventricular unloading by left ventricular assist device on the right ventricle geometry and function: effect of nitric oxide inhalation. J Thorac Cardiovasc Surg. 2011;141(4):1009–1014. doi: 10.1016/j.jtcvs.2010.08.010
   PubMed Web of Science ®Google Scholar
• Kapur NK, Paruchuri V, Korabathina R, et al. Effects of a percutaneous mechanical circulatory support device for medically refractory right ventricular failure. J Heart Lung Transplant. 2011;30(12):1360–1367. doi: 10.1016/j.healun.2011.07.005
   PubMed Web of Science ®Google Scholar
• Aggarwal V, Einhorn BN, Cohen HA. Current status of percutaneous right ventricular assist devices: first-in-man use of a novel dual lumen cannula. Catheter Cardiovasc Interv. 2016;88(3):390–396. doi: 10.1002/ccd.26348
   PubMed Web of Science ®Google Scholar
• John R, Long JW, Massey HT, et al. Outcomes of a multicenter trial of the levitronix centriMag ventricular assist system for short-term circulatory support. J Thorac Cardiovasc Surg. 2011;141(4):932–939. doi: 10.1016/j.jtcvs.2010.03.046
   PubMed Web of Science ®Google Scholar
• Daneshmand MA, Bishawi M, Milano CA, et al. The HeartMate 6. ASAIO J. 2020 Mar;66(3):e46–e49.
   PubMed Web of Science ®Google Scholar
• Potapov EV, Schweiger M, Stepanenko A, et al. Tricuspid valve repair in patients supported with left ventricular assist devices. ASAIO J. 2011;57(5):363–367. doi: 10.1097/01.MAT.0000398944.12757.eb
   PubMed Web of Science ®Google Scholar
• Piacentino V III, Troupes CD, Ganapathi AM, et al. Clinical impact of concomitant tricuspid valve procedures during left ventricular assist device implantation. Ann Thorac Surg. 2011;92(4):1414–1419. doi: 10.1016/j.athoracsur.2011.05.084
   PubMed Web of Science ®Google Scholar
• Brewer RJ, Cabrera R, El-Atrache M, et al. Relationship of tricuspid repair at the time of left ventricular assist device implantation and survival. Int J Artif Organs. 2014 Nov;37(11):834–838.
   PubMed Web of Science ®Google Scholar
• Nakanishi K, Homma S, Han J, et al. Usefulness of tricuspid annular diameter to predict late right sided heart failure in patients with left ventricular assist device. Am J Cardiol. 2018;122(1):115–120. doi: 10.1016/j.amjcard.2018.03.010
   PubMed Web of Science ®Google Scholar
• Xanthopoulos A, Tryposkiadis K, Triposkiadis F, et al. Postimplant phosphodiesterase type 5 inhibitors use is associated with lower rates of thrombotic events after left ventricular assist device implantation. J Am Heart Assoc. 2020;9(14):e015897. doi: 10.1161/JAHA.119.015897
   PubMed Web of Science ®Google Scholar
• Frantz RP, Desai S, Ewald G, et al. First results of soprano: macitentan in patients (pts) with pulmonary hypertension (PH) post-left ventricular assist device (LVAD) implantation. J Heart Lung Transplant. 2021 Apr 1;40(4, Supplement):S12–S13. doi: 10.1016/j.healun.2021.01.1767
   PubMedGoogle Scholar
• Song HK, Gelow JM, Mudd J, et al. Limited utility of tricuspid valve repair at the Time of left ventricular assist device implantation. Ann Thorac Surg. 2016;101(6):2168–2174. doi: 10.1016/j.athoracsur.2016.03.040
   PubMed Web of Science ®Google Scholar
• Robertson JO, Grau-Sepulveda MV, Okada S, et al. Concomitant tricuspid valve surgery during implantation of continuous-flow left ventricular assist devices: a society of thoracic surgeons database analysis. J Heart Lung Transplant. 2014;33(6):609–617. doi: 10.1016/j.healun.2014.01.861
   PubMed Web of Science ®Google Scholar
• Nair N. Use of machine learning techniques to identify risk factors for RV failure in LVAD patients. Front Cardiovasc Med. 2022;9:848789. doi: 10.3389/fcvm.2022.848789
   PubMed Web of Science ®Google Scholar
• Thohan V, Abraham J, Burdorf A, et al. Use of a pulmonary artery pressure sensor to manage patients with left ventricular assist devices. Circ Heart Fail. 2023;16(6):e009960. doi: 10.1161/CIRCHEARTFAILURE.122.009960
   PubMed Web of Science ®Google Scholar
• Kiernan MS, French AL, DeNofrio D, et al. Preoperative three-dimensional echocardiography to assess risk of right ventricular failure after left ventricular assist device surgery. J Card Fail. 2015;21(3):189–197. doi: 10.1016/j.cardfail.2014.12.009
   PubMed Web of Science ®Google Scholar
• Magunia H, Dietrich C, Langer HF, et al. 3D echocardiography derived right ventricular function is associated with right ventricular failure and mid-term survival after left ventricular assist device implantation. Int J Cardiol. 2018;272:348–355. doi: 10.1016/j.ijcard.2018.06.026
   PubMed Web of Science ®Google Scholar