138
Views
0
CrossRef citations to date
0
Altmetric
Original Research

The CXCLs-CXCR2 axis modulates the cross-communication between tumor-associated neutrophils and tumor cells in cervical cancer

, , , , , , & show all
Pages 559-569 | Received 23 Oct 2023, Accepted 08 Jan 2024, Published online: 24 Jan 2024

References

  • Sadik CD, Kim ND, Luster AD. Neutrophils cascading their way to inflammation. Trends Immunol. 2011 Oct;32(10):452–60. doi: 10.1016/j.it.2011.06.008
  • Han X, Shi H, Sun Y, et al. CXCR2 expression on granulocyte and macrophage progenitors under tumor conditions contributes to mo-MDSC generation via SAP18/ERK/STAT3. Cell Death Dis. 2019 Aug 8;10(8):598. doi: 10.1038/s41419-019-1837-1
  • Cheng Y, Mo F, Li Q, et al. Targeting CXCR2 inhibits the progression of lung cancer and promotes therapeutic effect of cisplatin. Mol Cancer. 2021 Apr 4;20(1):62. doi: 10.1186/s12943-021-01355-1
  • Wu F, Zhao Y, Jiao T, et al. CXCR2 is essential for cerebral endothelial activation and leukocyte recruitment during neuroinflammation. J Neuroinflammation. 2015 May 21;12(1):98. doi: 10.1186/s12974-015-0316-6
  • Korbecki J, Kupnicka P, Chlubek M, et al. CXCR2 receptor: regulation of expression, signal transduction, and involvement in cancer. Int J Mol Sci. 2022 Feb 16;23(4):2168. doi: 10.3390/ijms23042168
  • Korbecki J, Kojder K, Kapczuk P, et al. The effect of hypoxia on the expression of CXC chemokines and CXC chemokine receptors—A review of literature. IJMS. 2021 Jan 15;22(2):843. doi: 10.3390/ijms22020843
  • Wu S, Saxena S, Varney ML, et al. CXCR1/2 chemokine network regulates melanoma resistance to chemotherapies mediated by NF-kappaB. Curr Mol Med. 2017;17(6):436–449. doi: 10.2174/1566524018666171219100158
  • Okunade KS. Human papillomavirus and cervical cancer. J Obstet Gynaecol. 2020 Jul;40(5):602–608. doi: 10.1080/01443615.2019.1634030
  • Spurgeon ME, den Boon JA, Horswill M, et al. Human papillomavirus oncogenes reprogram the cervical cancer microenvironment independently of and synergistically with estrogen. Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):E9076–E9085. doi: 10.1073/pnas.1712018114
  • Boccardo E, Lepique AP, Villa LL. The role of inflammation in HPV carcinogenesis. Carcinogenesis. 2010 Nov;31(11):1905–12. doi: 10.1093/carcin/bgq176
  • Sun J, Yuan J. Chemokine (C-X-C motif) ligand 1/chemokine (C-X-C motif) receptor 2 autocrine loop contributes to cellular proliferation, migration and apoptosis in cervical cancer. Bioengineered. 2022 Mar;13(3):7579–7591. doi: 10.1080/21655979.2022.2036896
  • Zhang W, Wu Q, Wang C, et al. AKIP1 promotes angiogenesis and tumor growth by upregulating CXC-chemokines in cervical cancer cells. Mol Cell Biochem. 2018 Nov;448(1–2):311–320.
  • Zhang N, Pang C, Li Z, et al. Serum CXCL8 and CXCR2 as diagnostic biomarkers for noninvasive screening of cervical cancer. Medicine (Baltimore). 2023 Aug 25;102(34):e34977. doi: 10.1097/MD.0000000000034977
  • Carus A, Ladekarl M, Hager H, et al. Tumour-associated CD66b+ neutrophil count is an independent prognostic factor for recurrence in localised cervical cancer. Br J Cancer. 2013 May 28;108(10):2116–22. doi: 10.1038/bjc.2013.167
  • Matsumoto Y, Mabuchi S, Kozasa K, et al. The significance of tumor-associated neutrophil density in uterine cervical cancer treated with definitive radiotherapy. Gynecol Oncol. 2017 Jun;145(3):469–475.
  • Liu X, Ni G, Zhang P, et al. Single-nucleus RNA sequencing and deep tissue proteomics reveal distinct tumour microenvironment in stage-I and II cervical cancer. J Exp Clin Cancer Res. 2023 Jan 23;42(1):28. doi: 10.1186/s13046-023-02598-0
  • Thul PJ, Akesson L, Wiking M, et al. A subcellular map of the human proteome. Science. 2017 May 26;356(6340). doi: 10.1126/science.aal3321
  • H-Z J, Chen L, Ren M, et al. CXCL8 Promotes Endothelial-to-Mesenchymal Transition of Endothelial Cells and Protects Cells from Erastin-Induced Ferroptosis via CXCR2-Mediated Activation of the NF-κB Signaling Pathway. Pharma. 2023;16(9):1210. doi: 10.3390/ph16091210
  • Zeng D, Ye Z, Shen R, et al. IOBR: multi-omics immuno-oncology biological research to decode tumor microenvironment and signatures. Front Immunol. 2021;12:687975. doi: 10.3389/fimmu.2021.687975
  • Kuang Y, Parthasarathy U, Martinelli R. Protocol for density gradient neutrophil isolation and flow cytometry-based characterization from human peripheral blood. STAR Protoc. 2023 Aug 16;4(3):102497.
  • Zhou Z, Wang P, Sun R, et al. Tumor-associated neutrophils and macrophages interaction contributes to intrahepatic cholangiocarcinoma progression by activating STAT3. J Immunother Cancer. 2021 Mar;9(3):e001946.
  • Newman AM, Liu CL, Green MR, et al. Robust enumeration of cell subsets from tissue expression profiles. Nat Methods. 2015 May;12(5):453–7.
  • Cheng Y, Ma XL, Wei YQ, et al. Potential roles and targeted therapy of the CXCLs/CXCR2 axis in cancer and inflammatory diseases. Biochim Biophys Acta Rev Cancer. 2019 Apr;1871(2):289–312.
  • Sano M, Ijichi H, Takahashi R, et al. Blocking CXCLs-CXCR2 axis in tumor-stromal interactions contributes to survival in a mouse model of pancreatic ductal adenocarcinoma through reduced cell invasion/migration and a shift of immune-inflammatory microenvironment. Oncogenesis. 2019 Jan 18;8(2):8. doi: 10.1038/s41389-018-0117-8
  • Matsushima K, Yang D, Oppenheim JJ. Interleukin-8: An evolving chemokine. Cytokine. 2022 May;153: 155828. doi: 10.1016/j.cyto.2022.155828
  • Guan X. Cancer metastases: challenges and opportunities. Acta Pharm Sin B. 2015 Sep;5(5):402–18. doi: 10.1016/j.apsb.2015.07.005
  • Man X, Yang X, Wei Z, et al. High expression level of CXCL1/GROalpha is linked to advanced stage and worse survival in uterine cervical cancer and facilitates tumor cell malignant processes. BMC Cancer. 2022 Jun 28;22(1):712. doi: 10.1186/s12885-022-09749-0
  • Li JL, Lim CH, Tay FW, et al. Neutrophils self-regulate immune complex-mediated cutaneous inflammation through CXCL2. J Invest Dermatol. 2016 Feb;136(2):416–424.
  • Reyes N, Figueroa S, Tiwari R, et al. CXCL3 signaling in the tumor microenvironment. Adv Exp Med Biol. 2021;1302:15–24.
  • Tran le S, Mittal D, Mattarollo SR, et al. Interleukin-17A promotes arginase-1 production and 2,4-dinitrochlorobenzene-induced acute hyperinflammation in human papillomavirus E7 oncoprotein-expressing skin. J Innate Immun. 2015;7(4):392–404. doi: 10.1159/000374115
  • Gijsbers K, Gouwy M, Struyf S, et al. GCP-2/CXCL6 synergizes with other endothelial cell-derived chemokines in neutrophil mobilization and is associated with angiogenesis in gastrointestinal tumors. Exp Cell Res. 2005 Feb 15;303(2):331–42. doi: 10.1016/j.yexcr.2004.09.027
  • Capucetti A, Albano F, Bonecchi R. Multiple roles for chemokines in neutrophil biology. Front Immunol. 2020;11:1259. doi: 10.3389/fimmu.2020.01259
  • Jaillon S, Ponzetta A, Di Mitri D, et al. Neutrophil diversity and plasticity in tumour progression and therapy. Nat Rev Cancer. 2020 Sep;20(9):485–503.
  • Shaul ME, Fridlender ZG. Tumour-associated neutrophils in patients with cancer. Nat Rev Clin Oncol. 2019 Oct;16(10):601–620. doi: 10.1038/s41571-019-0222-4
  • Guan X, Lu Y, Zhu H, et al. The crosstalk between cancer cells and neutrophils enhances hepatocellular carcinoma metastasis via neutrophil extracellular traps-associated cathepsin G component: a potential therapeutic target. J Hepatocell Carcinoma. 2021;8:451–465. doi: 10.2147/JHC.S303588

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.