- Alt V, Bechert T, Steinrucke P, Wagener M, Seidel P, Ding-eldein E, Domann E, Schnettler R. An in vitro assessment of the antibacterial properties and cytotxicity of nanopar-ticulate silver bone cement. Biomaterials 2004; 25(18)4383–91
- Anagnostakos K, Kelm J, Regitz T, Schmitt E, Jung W. In vitro evaluation of antibiotic elution from and bacteria growth inhibition by antibiotic-loaded acrylic bone cement spacers. J Biomed Mater Res B Appl Biomater 2005; 72(2)373–8
- Anagnostakos K, Fürst O, Kelm J. Antibiotic-impregnated PMMA hip spacers: current status. Acta Orthop 2006; 77(4)628–37
- Arciola C R, Campoccia D, Montanaro L. Effects on antibiotic resistance of Staphylococcus epidermidis following adhesion to polymethylmethacrylate and to silicone surfaces. Biomaterials 2002; 23(6)1495–502
- Gonzalez Della Valle A, Bostrom M, Brause B, Harney C, Salvati E A. Effective bactericidal activity of tobramycin and vancomycin eluted from acrylic bone cement. Acta Orthop Scand 2001; 72(3)237–40
- Hanssen A D. Prophylactic use of antibiotic bone cement. An emerging standard-in opposition. J Arthroplasty (4 Suppl 1) 2004; 19: 73–7
- Hope P G, Kristinsson K G, Norman P, Elson R A. Deep infection of cemented total hip arthroplasties caused by coagulase-negative staphylococci. J Bone Joint Surg (Br) 1989; 71(5)851–4
- Kelm J, Anagnostakos K, Regitz T, Schmitt E, Schneider G, Ahlhelm F. MRSA-infections-treatment with intraopera-tively produced gentamycin-vancomycin PMMA beads. Chirurg 2004; 75(10)988–95
- Kendall R W, Duncan C P, Smith J A, Ngui-Yen J H. Persistence of bacteria on antibiotic loaded acrylic depots. Clin Orthop 1996, 329: 273–80
- Klekamp J, Dawson J M, Haas D W, DeBoer D, Christie M. The use of vancomycin and tobramycin in acrylic bone cement: biomechanical effects and elution kinetics for use in joint arthroplasty. J Arthroplasty 1999; 14(3)339–46
- Klemm K. Gentamicin-PMMA-beads in treating bone and soft tissue infections. Zentralbl Chir 1979; 104(14)934–42
- König D P, Schierholz J M, Hilgers R-D, Bertram C, Perdreau-Remington F, Rütt J. In vitro adherence and accumulation of Staphylococcus epidermidis RP 62 A and Staphylococcus epidermidis M7 on four different bone cements. Langenbeck's Arch Surg 2001; 386: 328–32
- Masri B A, Duncan C P, Beauchamp C P. Long-term elution of antibiotics from bone cement. An in vivo study using the prosthesis of antibiotic-loaded acrylic bone cement (PROSTALAC) system. J Arthroplasty 1998; 13(3)331–8
- Neut D, Van de Belt H, Stokroos I, Van Horn J R, Van der Mei H C, Busscher H J. Biomaterial-associated infection of getnamicin-loaded PMMA beads in orthopedic revision surgery. J Antimicrob Chemother 2001; 47(6)885–91
- Neut D, Hendriks J G E, Van Horn J R, Van der Mei H C, Busscher H J. Pseudomonas aeruginosa biofilm formation and slime excretion on antibiotic-loaded bone cement. Acta Orthop Scand 2005; 76(1)109–14
- Oga M, Arizono T, Sugioka Y. Inhibition of bacterial adherence to tobramycin-impregnated PMMA bone cement. Acta Orthop Scand 1992; 63(3)301–4
- Ozaki T, Yoshitaka T, Kunisada T, Dan'ura T, Naito N, Inoue H. Vancomycin-impregnated polymethylmethacrylate beads for methicillin-resistant Staphylococcus aureus (MRSA) infection: report of two cases. J Orthop Sci 1998; 3(3)163–8
- Penner M J, Masri B A, Duncan C P. Elution characteristics of tobramycin and vancomycin combined in acrylic bone cement. J Arthroplasty 1996; 11(8)939–44
- Thomes B, Murray P, Bouchier-Hayes D. Development of resistant strains of Staphylococcus epidermidis on genta-micin-loaded bone cement in vivo. J Bone Joint Surg (Br) 2002; 84(5)758–60
- Van de Belt H, Neut D, Schenk W, Van Horn J R, Van der Mei H C, Busscher H J. Gentamicin release form polymethylmethacrylate bone cements and Staphylococcus aureus biofilm formation. Acta Orthop Scand 2000; 71(6)625–9
- Von Eiff C, Proctor R A, Peters G. Staphylococcus aureus small colony variants: formation and clinical impact. Int J Clin Pract (Suppl) 2000; 115: 44–9
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Persistence of bacterial growth on antibiotic-loaded beads: Is it actually a problem?
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