Spaceflight associated neuro-ocular syndrome (SANS): a systematic review, implications for the sans case definition

References

• Martin PY, Mudie LI, Subramanian PS. Spaceflight associated neuro-ocular syndrome (SANS): a systematic review and future directions. Eye Brain. 2020 Oct 19;12:105–117. doi: 10.2147/EB.S234076
   PubMed Web of Science ®Google Scholar
• Hailey M, Urbina M, Hughlett J, et al. Evaluating the medical kit system for the international space station a paradigm revisited. In: 82nd Annual Scientific and Human Performance Meeting of the Aerospace Medical Association. JSC-CN-23382. 2011 May; Houston, TX, USA.
   Google Scholar
• Mader TH, Gibson CR, Pass AF, et al. Optic disc edema, globe flattening, choroidal folds, and hyperopic shifts observed in astronauts after long-duration space flight. Ophthalmol. 2011 Oct;118(10):2058–2069.
   PubMed Web of Science ®Google Scholar
• Stenger MB, Tarver WJ, Brunstetter T, et al. Evidence report: risk of spaceflight associated neuro-ocular syndrome (SANS). No. JSC-E-DAA-TN49801. In: Lyndon BJ, editor. National Aeronautics and Space Administration, Lyndon B. Houston (TX): Johnson Space Center; 2017 Nov 30;38–42.
   Google Scholar
• Lee AG, Mader TH, Gibson CR, et al. Spaceflight associated neuro-ocular syndrome (SANS) and the neuro-ophthalmologic effects of microgravity: a review and an update. NPJ Microgravity. 2020 Feb 7;6(1):7. doi: 10.1038/s41526-020-0097-9
   PubMed Web of Science ®Google Scholar
• Lee AG, Mader TH, Gibson CR, et al. Space flight-associated neuro-ocular syndrome. JAMA Ophthalmol. 2017 Sep 1;135(9):992–994. doi: 10.1001/jamaophthalmol.2017.2396
   PubMed Web of Science ®Google Scholar
• Page MJ, McKenzie JE, Bossuyt PM, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021 Mar 29;372:n71. doi: 10.1136/bmj.n71
   PubMed Web of Science ®Google Scholar
• National Heart and Blood Institute L. Health NI of, Services USD of H and H. Study quality assessment tools [Internet]. [cited 2022 Dec 6]. Available from: https://www.nhlbi.nih.gov/health-topics/study-quality-assessment-tools
   Google Scholar
• Lo CK, Mertz D, Loeb M. Newcastle-Ottawa scale: comparing reviewers’ to authors’ assessments. BMC Med Res Methodol. 2014 Apr 1;14(1):45.
   PubMed Web of Science ®Google Scholar
• Balduzzi S, Rücker G, Schwarzer G. How to perform a meta-analysis with R: a practical tutorial. Evid Based Ment Health. 2019 Nov;22(4):153–160. doi: 10.1136/ebmental-2019-300117
   PubMed Web of Science ®Google Scholar
• The R Project for Statistical Computing [Internet]. Vienna: The R Foundation; 2018 [cited 2023 Nov 30]. Available from: https://www.r-project.org/
   Google Scholar
• Johnston A. Standard deviation. Commun Int [Internet]. 2002;29(8):36. [cited 2022 Dec 6]. Available from: https://www.calculator.net
   Google Scholar
• Sater SH, Rohr JJ, Sass AM, et al. Magnetic resonance imaging quantification of ophthalmic changes due to spaceflight. Fluids Barriers CNS. 2019;16:177.
   Google Scholar
• Marshall-Bowman K, Barratt MR, Gibson CR. Ophthalmic changes and increased intracranial pressure associated with long duration spaceflight: an emerging understanding. Acta Astronaut. 2013;87:77–87. doi: 10.1016/j.actaastro.2013.01.014
   Web of Science ®Google Scholar
• Mader TH, Gibson CR, Otto CA, et al. Persistent asymmetric optic disc swelling after long-duration space flight: implications for pathogenesis. J Neuroophthalmol. 2017;37(2):133–139. doi: 10.1097/WNO.0000000000000467
   PubMed Web of Science ®Google Scholar
• Patel N, Pass A, Mason S, et al. Optical coherence tomography analysis of the optic nerve head and surrounding structures in long-duration international space station astronauts. JAMA Ophthalmol. 2018 Feb 1;136(2):193–200. doi: 10.1001/jamaophthalmol.2017.6226
   PubMed Web of Science ®Google Scholar
• Macias BR, Patel NB, Gibson CR, et al. Association of long-duration spaceflight with anterior and posterior ocular structure changes in astronauts and their recovery. JAMA Ophthalmol. 2020 May 1;138(5):553–559. doi: 10.1001/jamaophthalmol.2020.0673
   PubMed Web of Science ®Google Scholar
• Kramer LA, Sargsyan AE, Hasan KM, et al. Orbital and intracranial effects of microgravity: findings at 3-T MR imaging. Radiology. 2012 Jun;263(3):819–827. doi: 10.1148/radiol.12111986
   PubMed Web of Science ®Google Scholar
• Mader TH, Gibson CR, Pass AF, et al. Optic disc edema in an astronaut after repeat long-duration space flight. J Neuroophthalmol. 2013 Sep;33(3):249–255.
   PubMed Web of Science ®Google Scholar
• Makarov IA, Danilichev SN. Papilledema in space flight: pathogenesis, diagnostics and monitoring. Ophthalmol Russ. 2020;17(4):752–760. doi: 10.18008/1816-5095-2020-4-752-760
   Google Scholar
• Rohr JJ, Sater S, Sass AM, et al. Quantitative magnetic resonance image assessment of the optic nerve and surrounding sheath after spaceflight. NPJ Microgravity. 2020 Oct 8;6:30. doi: 10.1038/s41526-020-00119-3
   PubMed Web of Science ®Google Scholar
• Iwasaki KI, Ogawa Y, Kurazumi T, et al. Long-duration spaceflight alters estimated intracranial pressure and cerebral blood velocity. J Physiol. 2021 Feb;599(4):1067–1081.
   PubMed Web of Science ®Google Scholar
• Buckey JC, Phillips SD, Anderson AP, et al. Microgravity-induced ocular changes are related to body weight. Am J Physiol Regul Integr Comp Physiol. 2018 Sep 1;315(3):R496–R499. doi: 10.1152/ajpregu.00086.2018
   PubMed Web of Science ®Google Scholar
• Zwart SR, Gregory JF, Zeisel SH, et al. Genotype, B-vitamin status, and androgens affect spaceflight-induced ophthalmic changes. FASEB J. 2016 Jan;30(1):141–148.
   PubMed Web of Science ®Google Scholar
• Laurie SS, Lee SMC, Macias BR, et al. Optic Disc Edema and choroidal engorgement in astronauts during spaceflight and individuals exposed to bed rest. JAMA Ophthalmol. 2020 Feb 1;138(2):165–172. doi: 10.1001/jamaophthalmol.2019.5261
   PubMed Web of Science ®Google Scholar
• Wåhlin A, Holmlund P, Fellows AM, et al. Optic nerve length before and after spaceflight. Ophthalmol. 2021 Feb;128(2):309–316. doi: 10.1016/j.ophtha.2020.07.007
   PubMed Web of Science ®Google Scholar
• Mader TH, Gibson CR, Barratt MR, et al. Persistent globe flattening in astronauts following long-duration spaceflight. Neuroophthal-mology. 2020 Sep 3;45(1):29–35. doi: 10.1080/01658107.2020.1791189
   PubMed Web of Science ®Google Scholar
• Sater SH, Sass AM, Rohr JJ, et al. Automated MRI-based quantification of posterior ocular globe flattening and recovery after long-duration spaceflight. Eye. 2021;35(7):1869–1878. doi: 10.1038/s41433-021-01408-1
   PubMed Web of Science ®Google Scholar
• Killer HE, Jaggi GP, Miller NR. Papilledema revisited: is its pathophysiology really understood? Clin Exp Ophthalmol. 2009;37(5):444–447. doi: 10.1111/j.1442-9071.2009.02059.x
   PubMed Web of Science ®Google Scholar
• Mader TH, Gibson CR, Pass AF, et al. Optic disc edema, globe flattening, choroidal folds, and hyperopic shifts observed in astronauts after long-duration space flight. Ophthalmol. 2011;118(10):2058–2069. doi: 10.1016/j.ophtha.2011.06.021
   PubMed Web of Science ®Google Scholar
• Cassidy LM, Sanders MD. Choroidal folds and papilloedema. Br J Ophthalmol. 1999;83(10):1139–1143. doi: 10.1136/bjo.83.10.1139
   PubMed Web of Science ®Google Scholar
• Sibony PA, Laurie SS, Ferguson CR, et al. Ocular deformations in spaceflight-associated neuro-ocular syndrome and idiopathic intracranial hypertension. Invest Ophthalmol Vis Sci. 2023 Mar 1;64(3):32. doi: 10.1167/iovs.64.3.32
   PubMed Web of Science ®Google Scholar
• Schmidt D. The mystery of cotton-wool spots - a review of recent and historical descriptions. Eur J Med Res. 2008 Jun 24;13(6):231–266. doi: 10.1159/000351088
   PubMed Web of Science ®Google Scholar
• Gomez ML, Mojana F, Bartsch DU, et al. Imaging of long-term retinal damage after resolved cotton wool spots. Ophthalmol. 2009 Dec;116(12):2407–2414. doi: 10.1016/j.ophtha.2009.05.012
   PubMed Web of Science ®Google Scholar
• Seregard S, Pelayes DE, Singh AD. Radiation therapy: posterior segment complications. Dev Ophthalmol. 2013;52:114–123. doi: 10.1159/000351088
   PubMedGoogle Scholar