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ORIGINAL ARTICLE

Role of enteral ebselen and ethylhydroxyethyl cellulose in pancreatitis-associated multiple-organ dysfunction in humans

, , , & , MD , PhD
Pages 43-50 | Published online: 11 Jul 2009

References

  • Blum T, Maisonneuve P, Lowenfels AB, Lankisch PG. Fatal outcome in acute pancreatitis: its occurrence and early prediction. Pancreatology 2001; 1: 237–41
  • Gloor B, Müller CH, Worny M, Martignoni ME, Uhl W, Büchler MW. Late mortality in patients with severe acute pancreatitis. Br J Surg 2001; 88: 975–9
  • Wang XD. Organ dysfunction: a systemic consequence of acute and chronic diseases. J Organ Dysfunct 2005; 1: 2–3
  • Halonen KI, Pettila V, Leppaniemi AK, Kemppainen EA, Puolakkainen PA, Haapiainen RK. Multiple organ dysfunction associated with severe acute pancreatitis. Crit Care Med 2002; 30: 1274–9
  • Zimmerman JE, Knaus WA, Wagner DP, Sun X, Hakim RB, Nystrom PO. A comparison of risks and outcomes for patients with organ system failure: 1982–1990. Crit Care Med 1996; 24: 1633–41
  • Tran DD, Cuesta MA, van Leeuwen PA, Nauta JJ, Wesdorp RI. Risk factors for multiple organ system failure and death in critically injured patients. Surgery 1993; 114: 21–30
  • Wang XD, Andersson R, Soltezs V, Ihse I. Gut origin sepsis, macrophage function, and oxygen extraction in acute pancreatitis in the rat. World J Surg 1996; 20: 299–308
  • Andersson R, Wang XD. Potential mechanisms of gut origin sepsis in experimental acute pancreatitis. Ann Acad Med Singapore 1999; 28: 141–6
  • Shi CB, Andersson R, Zhao X, Wang XD. Potential role of reactive oxygen species in pancreatitis-associated multiple organ dysfunction. Pancreatology 2005; 5: 492–500
  • Wang XD, Sun ZW, Börjesson A, Andersson R. Inhibition of platelet-activating factor, intercellular adhesion molecule-1, and platelet endothelial cell adhesion molecule-1 reduces pancreatitis-associated gut endothelial dysfunction in rats. Br J Surg 1999; 86: 411–6
  • Zhao H, Zhao X, Bai CX, Wang XD. Potential factors of interorgan signals in the development of pancreatitis-associated acute lung injury and acute respiratory distress syndrome. J Organ Dysfunct 2005; 1: 32–44
  • Avgerinos C, Delis S, Rizos S, Dervenis C. Nutritional support in acute pancreatitis. Dig Dis 2003; 21: 214–19
  • Gupta R, Patel K, Calder PC, Yaqoob P, Primrose JN, Johnson CD. A randomised clinical trial to assess the effect of total enteral and total parenteral nutritional support on metabolic, inflammatory and oxidative markers in patients with predicted severe acute pancreatitis (APACHE II > or = 6). Pancreatology 2003; 3: 406–13
  • Olah A, Belagyi T, Issekutz A, Gamal ME, Bengmark S. Randomized clinical trial of specific lactobacillus and fibre supplement to early enteral nutrition in patients with acute pancreatitis. Br J Surg 2002; 89: 1103–7
  • Wang XD, Parsson H, Soltesz V, Johansson K, Andersson R. Bacterial translocation and intestinal capillary permeability following major liver resection in the rat. J Surg Res 1995; 58: 351–8
  • Wang XD, Andersson R, Soltesz V, Guo W, Bengmark S. Water-soluble ethylhydroxyethyl cellulose prevents bacterial translocation induced by major liver resection in the rat. Ann Surg 1993; 217: 155–67
  • Wang XD, Soltesz V, Guo W, Andersson R. Water-soluble ethylhydroxyethyl cellulose: a new agent against bacterial translocation from the gut after major liver resection. Scand J Gastroenterol 1994; 29: 833–40
  • Wang X, Guo W, Wang Q, Soltesz V, Andersson R. Effects of a water-soluble ethylhydroxyethyl cellulose on gut physiology, bacteriology, and bacterial translocation in acute liver failure. J Invest Surg 1995; 8: 65–84
  • Niederau C, Ude K, Niederau M, Luthen R, Strohmeyer G, Ferrell LD, et al. Effects of the seleno-organic substance Ebselen in two different models of acute pancreatitis. Pancreas 1991; 6: 282–90
  • Wang XD, Deng XM, Haraldsen P, Andersson R, Ihse I. Antioxidant and calcium channel blockers counteract endothelial barrier injury induced by acute pancreatitis in rats. Scand J Gastroenterol 1995; 30: 1129–36
  • Wang XD, Andersson R, Soltesz V, Wang WQ, Ar'Rajab A, Bengmark S. Phospholipids prevent enteric bacterial translocation in the early stage of experimental acute liver failure in the rat. Scand J Gastroenterol 1994; 29: 1117–21
  • Yamaguchi T, Sano K, Takakura K, Saito I, Shinohara Y, Asano T, et al. Ebselen in acute ischemic stroke: a placebo-controlled, double-blind clinical trial. Stroke 1998; 29: 12–17
  • Blamey SL, Imrie CW, O'Neil J, Gilmour WM, Carter DC. Prognostic factors in acute pancreatitis. Gut 1984; 25: 1340–6
  • Knaus WA, Draper EA, Wagner DP, Zimmerman JE. APACHE II: a severity of disease classification system. Crit Care Med 1985; 13: 818–29
  • Ranson J, Rifkind K, Roses D, Fink S, Eng K, Spencer FC. Prognostic signs and the role of operative management in acute pancreatitis. Surg Gynecol Obstet 1974; 139: 69–81
  • Marshall J, Cook D, Christnou N, Bernard G, Sprung C, Sibbald W. Multiple organ dysfunction score: a reliable descriptor of a complex clinical outcome. Crit Care Med 1995; 23: 1638–52
  • Ogawa A, Yoshimoto T, Kikuchi H, Sano K, Saito I, Yamaguchi T, et al. Ebselen in acute middle cerebral artery occlusion: a placebo-controlled, double-blind clinical trial. Cerebrovasc Dis 1999; 9: 112–18
  • Rothlein R, Czajkowski M, O'Neill MM, Marlin SD, Mainolfi E, Merluzzi VJ. Induction of intercellular adhesion molecule 1 on primary and continuous cell lines by pro-inflammatory cytokines: regulation by pharmacologic agents and neutralizing antibodies. J Immunol 1998; 141: 1665–9
  • Keicho N, Elliott WM, Hogg JC, Hayashi S. Adenovirus E1A gene dysregulates ICAM-1 expression in transformed pulmonary epithelial cells. Am J Respir Cell Mol Biol 1997; 16: 23–30
  • Andersson R, Wang X. Patterns of pancreatic cell death: apoptosis versus oncosis. Pancreas 1998; 17: 281–8
  • Bengmark S. Prospect for a new and rediscovered form of therapy: probiotic and phage. Fighting infection in the 21st century, PW Andrew, P Oystrom, GL Smith, DE Stewart-Tull. Blackwells, London 2000; 97–132
  • Powell JJ, Murchison JT, Fearon KC, Ross JA, Siriwardena AK. Randomized controlled trial of the effect of early enteral nutrition on markers of the inflammatory response in predicted severe acute pancreatitis. Br J Surg 2000; 87: 1375–81
  • Wilmer A. ICU management of severe acute pancreatitis. Eur J Intern Med 2004; 15: 274–80
  • Cotgreave IA, Duddy SK, Kass GE, Thompson D, Moldeus P. Studies on the anti-inflammatory activity of ebselen: ebselen interferes with granulocyte oxidative burst by dual inhibition of NADPH oxidase and protein kinase C. Biochem Pharmacol 1989; 38: 649–56
  • Wendel A, Kuesters S, Tiegs G. Ebselen: an in vivo immune response modifier. Biomed Environ Sci 1997; 10: 253–62
  • Dimmeler S, Brüne B, Ullrich V. Ebselen prevents inositol (1,4,5)-trisphosphate binding to its receptor. Biochem Pharmacol 1991; 42: 1151–3
  • Ozaki M, Nakamura M, Teraoka S, Ota K. Ebselen, a novel anti-oxidant compound, protects the rat liver from ischemia-reperfusion injury. Transplant Int 1997; 10: 96–102
  • Ramakrishnan N, Kalinich JF, McClain DE. Ebselen inhibition of apoptosis by reduction of peroxides. Biochem Pharmacol 1996; 51: 1443–51
  • Parnham M, Sies H. Ebselen: prospective therapy for cerebral ischaemia. Expert Opin Investig Drugs 2000; 9: 607–19
  • Windsor AC, Kanwar S, Li AG, Barnes E, Guthrie JA, Spark JI, et al. Compared with parenteral nutrition, enteral feeding attenuates the acute phase response and improves disease severity in acute pancreatitis. Gut 1998; 42: 431–5
  • Mortele KJ, Wiesner W, Intriere L, Shankar S, Zou KH, Kalantari BN, et al. A modified CT severity index for evaluating acute pancreatitis: improved correlation with patient outcome. AJR Am J Roentgenol 2004; 183: 1261–5
  • Kingsnorth AN, Galloway SW, Formela LJ. Randomized, double-blind phase II trial of Lexipafant, a platelet-activating factor antagonist, in human acute pancreatitis. Br J Surg 1995; 82: 1414–20
  • Hall LG, Oyen LJ, Taner CB, Cullinane DC, Baird TK, Cha SS, et al. Fixed-dose vasopressin compared with titrated dopamine and norepinephrine as initial vasopressor therapy for septic shock. Pharmacotherapy 2004; 24: 1002–12
  • Mayer J, Rau B, Gansauge F, Beger HG. Inflammatory mediators in human acute pancreatitis: clinical and pathophysiological implications. Gut 2000; 47: 546–52
  • Mentula P, Kylanpaa ML, Kemppainen E, Jansson SE, Sarna S, Puolakkainen P, et al. Early prediction of organ failure by combined markers in patients with acute pancreatitis. Br J Surg 2004; 92: 68–75
  • Rau B, Baumgart K, Kruger CM, Schilling M, Beger HG. CC-chemokine activation in acute pancreatitis: enhanced release of monocyte chemoattractant protein-1 in patients with local and systemic complications. Intensive Care Med 2003; 29: 622–9
  • Powell JJ, Fearon KC, Siriwardena AK, Ross JA. Evidence against a role for polymorphisms at tumor necrosis factor, interleukin-1 and interleukin-1 receptor antagonist gene loci in the regulation of disease severity in acute pancreatitis. Surgery 2001; 129: 633–40
  • Pastor CM, Rubbia-Brandt L, Hadengue A, Jordan M, Morel P, Frossard JL. Role of macrophage inflammatory peptide-2 in cerulein-induced acute pancreatitis and pancreatitis-associated lung injury. Lab Invest 2003; 83: 471–8
  • Haddad EB, McCluskie K, Birrell MA, Dabrowski D, Pecoraro M, Underwood M, et al. Differential effects of ebselen on neutrophil recruitment, chemokine, and inflammatory mediator expression in a rat model of lipopolysaccharide-induced pulmonary inflammation. J Immunol 2002; 169: 974–82

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