Association of polymorphisms in vascular endothelial growth factor gene with the age of onset of amyotrophic lateral sclerosis

References

• Siddique T., Lalani I. Genetic aspects of amyotrophic lateral sclerosis. Adv Neurol 2002; 88: 21–32
   PubMedGoogle Scholar
• Andersen P. M. Genetics of sporadic ALS. Amyotroph Lateral Scler Other Motor Neuron Disord 2001; 2((Suppl 1))37–41
   Google Scholar
• Hand C. K., Rouleau G. A. Familial amyotrophic lateral sclerosis. Muscle Nerve 2002; 25: 135–59
   PubMed Web of Science ®Google Scholar
• Bruijn L. I., Miller T. M., Cleveland D. W. Unravelling the mechanisms involved in motor neuron degeneration in ALS. Annu Rev Neurosci 2004; 27: 723–49
   PubMed Web of Science ®Google Scholar
• Mulder D. W. Clinical limits of amyotrophic lateral sclerosis. Adv Neurol 1982; 36: 15–22
   PubMedGoogle Scholar
• Fernández‐Santiago R., Sharma M., Mueller J. C., Gohlke H., Illig T., Anneser J., et al. Possible gender‐dependent association of vascular endothelial growth factor gene and ALS. Neurology 2006; 66: 1929–31
   PubMed Web of Science ®Google Scholar
• Panas M., Karadima G., Kalfakis N., Psarrou O., Floroskoufi P., Kladi A., et al. Genotyping of presenilin‐1 polymorphism in amyotrophic lateral sclerosis. J Neurol 2000; 247: 940–2
   PubMed Web of Science ®Google Scholar
• Veldink J. H., van den Berg L. H., Cobben J. M., Stulp R. P., De Jong J. M. B. V., Vogels O. J., et al. Homozygous deletion of the survival motor neuron 2 gene is a prognostic factor in sporadic ALS. Neurology 2001; 56: 749–52
   PubMed Web of Science ®Google Scholar
• Siddique T., Pericak‐Vance M. A., Caliendo J., et al. Lack of association between apolipoprotein E genotype and sporadic amyotrophic lateral sclerosis. Neurogenetics 1998; 1: 213–6
   PubMed Web of Science ®Google Scholar
• Lacomblez L., Doppler V., Beucler I., Costes G., Salachas F., Raisonnier A. APOE: a potential marker of disease progression in ALS. Neurology 2002; 58: 1112–4
   PubMed Web of Science ®Google Scholar
• Sondell M., Lundborg G., Kanje M. The vascular endothelial growth factor has neurotrophic activity and stimulates axonal outgrowth, enhancing cell survival and Schwann cell proliferation in the peripheral nervous system. J Neurosci 1999; 19: 5731–40
   PubMed Web of Science ®Google Scholar
• Schratzberger P., Schratzberger G., Silver M., Curry C., Kearney M., Magner M., et al. Favourable effect of the vascular endothelial growth factor gene transfer on ischaemic peripheral neuropathy. Nat Med 2000; 6: 405–13
   PubMed Web of Science ®Google Scholar
• Jin K., Zhu Y. H., Sun Y. J., Mao X. O., Xie L., Greenberg D. A. The vascular endothelial growth factor stimulates neurogenesis in vitro and in vivo. P Natl Acad Sci USA 2002; 99: 11946–50
   PubMed Web of Science ®Google Scholar
• Tischer E., Mitchell R., Hartman T., Silva M., Gospodarowicz D., Fiddes J. C., et al. The human gene for the vascular endothelial growth factor: multiple protein forms are encoded through alternative exon splicing. J Biol Chem 1991; 266: 11947–54
   PubMed Web of Science ®Google Scholar
• Vincenti V., Caterina C., Rocchi M., Persico M. Assignment of the vascular endothelial growth factor gene to human chromosome 6P21.3. Circulation 1996; 93: 1493–5
   PubMed Web of Science ®Google Scholar
• I. J. Brogan, N. Khan, K. Isaac, J. A. Hutchinson, V. Pravica, I. V. Hutchinson. 1999. Novel polymorphisms in the promoter and 5′ UTR regions of the human vascular endothelial growth factor gene., Hum Immunol, 60, 1245-9
   Google Scholar
• Lambrechts D., Storkebaum E., Morimoto M., Del‐Favero J., Desmet F., Marklund S. L., et al. VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motor neurons against ischaemic death. Nature Genet 2003; 34: 383–94
   PubMed Web of Science ®Google Scholar
• Zhang Y., Zhang H., Fu Y., Song H., Wang L., Zhang J., et al. VEGF C2578A polymorphism does not contribute to amyotrophic lateral sclerosis susceptibility in sporadic Chinese patients. Amyotroph Lateral Scler Other Motor Neuron Disord 2006; 7: 119–22
   Web of Science ®Google Scholar
• Brogan I. J., et al. Novel polymorphisms in the promoter and 5′ UTR regions of the human vascular endothelial growth factor gene. Hum Immunol 1999; 60: 1245–9
   PubMed Web of Science ®Google Scholar
• Sondell M., Lundborg G., Kanje M. Vascular endothelial growth factor has neurotrophic activity and stimulates axonal outgrowth, enhancing cell survival and Schwann cell proliferation in the peripheral nervous system. J Neurosci 1999; 19: 5731–40
   PubMed Web of Science ®Google Scholar
• Ilzecka J. Cerebrospinal fluid vascular endothelial growth factor in patients with amyotrophic lateral sclerosis. Clin Neurol Neurosurg 2004; 106: 289–93
   PubMed Web of Science ®Google Scholar
• Carmeliet P. Mechanisms of angiogenesis and arteriogenesis. Nat Med 2000; 6: 389–95
   PubMed Web of Science ®Google Scholar
• Oosthuyse B., Moons L., Storkebaum E., Beck H., Nuyens D., Brusselmans K., et al. Deletion of the hypoxia‐response element in the vascular endothelial growth factor promoter causes motor neuron degeneration. Nature Genet 2001; 28: 131–8
   PubMed Web of Science ®Google Scholar
• Semenza G. L. Expression of hypoxia‐inducible factor 1: mechanisms and consequences. Biochem Pharmacol 2000; 59: 47–53
   PubMed Web of Science ®Google Scholar
• Murakami T., Ilieva H., Shiote M., Nagata T., Nagano I., Shoji M., et al. Hypoxic induction of vascular endothelial growth factor is selectively impaired in mice carrying the mutant SOD1 gene. Brain Res 2003; 989: 231–7
   PubMed Web of Science ®Google Scholar
• Carmeliet P. Blood vessels and nerves: common signals, pathways and diseases. Nature Rev Genet 2003; 4: 710–20
   PubMed Web of Science ®Google Scholar
• Schratzberger P., Schratzberger G., Silver M., Curry C., Kearney M., Magner M., et al. Favourable effect of VEGF gene transfer on ischaemic peripheral neuropathy. Nature Med 2000; 6: 405–13
   PubMed Web of Science ®Google Scholar
• Jin K. L., Mao X. O., Greenberg D. A. Vascular endothelial growth factor: direct neuroprotective effect in in vitro ischaemia. Proc Natl Acad Sci USA 2000; 97: 10242–7
   PubMed Web of Science ®Google Scholar
• van den Bosch L., Storkebaum E., Vleminckx V., Moons L., Vanopdenbosch L., Scheveneels W., et al. Effects of vascular endothelial growth factor on motor neuron degeneration. Neurobiol Dis 2004; 17: 21–8
   PubMed Web of Science ®Google Scholar
• Matsuzaki H., Tamatani M., Yamaguchi A., Namikawa K., Kiyama H., Vitek M. P., et al. Vascular endothelial growth factor rescues hippocampal neurons from glutamate‐induced toxicity: signal transduction cascades. FASEB J 2001; 15: 1218–20
   PubMed Web of Science ®Google Scholar
• Li B., Xu W., Luo C., Gozal D., Liu R. VEGF‐induced activation of the PI3‐K/Akt pathway reduces mutant SOD1‐mediated motor neuron cell death. Brain Res Mol Brain Res 2003; 111: 155–64
   PubMedGoogle Scholar
• Azzouz M., Ralph G. S., Storkebaum E., Walmsley L. E., Mitrophanous K. A., Kingsman S. M., et al. VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model. Nature 2004; 429: 413–7
   PubMed Web of Science ®Google Scholar
• Zheng C., Nennesmo I., Fadeel B., Henter J. I. Vascular endothelial growth factor prolongs survival in a transgenic mouse model of ALS. Ann Neurol 2004; 56: 564–7
   PubMed Web of Science ®Google Scholar
• Moreau C., Devos D., Brunaud‐Danel V., Defebvre L., Perez T., Destee A., et al. Paradoxical response of VEGF expression to hypoxia in CSF of patients with ALS. J Neurol Neurosurg Psychiatry 2006; 77: 255–7
   PubMed Web of Science ®Google Scholar
• Devos D., Moreau C., Lassalle P., Perez T., De Seze J., Brunaud‐Danel V., et al. Low levels of the vascular endothelial growth factor in CSF from early ALS patients. Neurology 2004; 62: 2127–9
   PubMed Web of Science ®Google Scholar
• Manly K. F. Conventional p‐values fail to assure reproducibility for genetic association tests. Trends Genet 2005; 21: 268–9
   PubMed Web of Science ®Google Scholar