199
Views
18
CrossRef citations to date
0
Altmetric
Original Article

Neuromuscular dysfunction in the mutant superoxide dismutase mouse model of amyotrophic lateral sclerosis

, , , , , & show all
Pages 24-34 | Received 25 May 2007, Accepted 14 Aug 2007, Published online: 10 Jul 2009

References

  • Gurney M. E., Pu H., Chiu A. Y., Dal Canto M. C., Polchow C. Y., Alexander D. D., et al. Motor neuron degeneration in mice that express a human Cu/Zn superoxide dismutase mutation. Science 1994; 264: 1772–5
  • Boillee S., Yamanaka K., Lobsiger C. S., Copeland N. G., Jenkins N. A., Kassiotis G., et al. Onset and progression in inherited ALS determined by motor neurons and microglia. Science 2006; 312: 1389–92
  • Mohajeri M. H., Figlewicz D. A., Bohn M. C. Selective loss of motor neurons innervating the medial gastrocnemius muscle in a mouse model of amyotrophic lateral sclerosis. Exp Neurol 1998; 50: 329–36
  • Ligon L. A., LaMonte B. H., Wallace K. E., Weber N., Kalb R. G., Holzbaur E. L. F. Mutant superoxide dismutase disrupts cytoplasmic dynein in motor neurons. Neuroreport 2005; 6: 533–6
  • Atkin J. D., Scott R. L., West J. M., Lopes E., Quah A. K. J., Cheema S. S. Properties of slow‐ and fast‐twitch muscle fibres in a mouse model of amyotrophic lateral sclerosis. Neuromusc Dis 2005; 15: 377–88
  • Kong J., Xu Z. Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing mutant SOD1. J Neurosci 1998; 18: 3241–50
  • Fischer L. R., Culver D. G., Tennant P., Davis A. A., Wang M., Castellano‐Sanchez A., et al. Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man. Exp Neurol 2004; 185: 232–40
  • Derave W., van den Bosch L., Lemmens G., Eijnde B. O., Robberecht W., Hespel P. Skeletal muscle properties in a transgenic mouse model for amytrophic lateral sclerosis: effects of creatine treatment. Neurobiol Dis 2003; 13: 264–72
  • Leger B., Vergani L., Soraru G., Hespel P., Gobelet C., D'Ascenzio C., et al. Human skeletal muscle atrophy in amyotrophic lateral sclerosis reveals a reduction in Akt and an increase in atrogin‐1. FASEB J 2006; 20: 583–5
  • Rommel C., Bodine S. C., Clarke B. A., Rossman R., Nunez L., Stitt T. N., et al. Mediation of IGF‐1‐induced skeletal myotube hypertrophy by PI(3)K/PKB/mTOR and PI(3)K/PKB/GSK3 pathways. Nat Cell Biol 2004; 3: 1009–13
  • Li M., Li C., Parkhouse W. S. Age‐related differences in the des IGF‐I‐mediated activation of PKB‐1 and p70 S6K in mouse skeletal muscle. Mech Ageing Dev 2003; 124: 771–8
  • Dudek S. M., Fields R. D. Mitogen‐activated protein kinase/extracellular signal‐regulated kinase activation in somatodendritic compartments: roles of action potentials, frequency, and mode of calcium entry. J Neurosci 2001; 21: 1–5
  • Hu J. H., Chernoff K., Pelech S., Krieger C. Protein kinase and protein phosphatase expression in the central nervous system of G93A mSOD overexpressing mice. J Neurochem 2003; 85: 422–31
  • Zhang H., Shi X., Zhang Q. J., Hampong M., Paddon H., Wahyuningsih D., et al. Nocodazole‐induced p53‐dependent c‐Jun N‐terminal kinase activation reduces apoptosis in human colon carcinoma HCT116 cells. J Biol Chem 2002; 277: 43648–58
  • Covault J., Sanes J. R. Distribution of N‐CAM in synaptic and extrasynaptic portions of developing and adult skeletal muscle. J Cell Biol 1986; 102: 716–30
  • Feeney S. J., McKelvie P. A., Austin L., Jean‐Francois M. J., Kapsa R., Tombs S. M., et al. Presymptomatic motor neuron loss and reactive astrocytosis in the SOD1 mouse model of amyotrophic lateral sclerosis. Muscle Nerve 2001; 24: 1510–9
  • Frey D., Schneider C., Xu L., Borg J., Spooren W., Caroni P. Early and selective loss of neuromuscular synapse subtypes with low sprouting competence in motor neuron diseases. J Neurosci 2000; 20: 2534–42
  • Kieran D., Hafezparast M., Bohnert S., Dick J. R. T., Martin J., Schiavo G., et al. A mutation in dynein rescues axonal transport defects and extends the life span of ALS mice. J Cell Biol 2005; 169: 561–7
  • Li S., Wang X., Klee C. B., Krieger C. Overexpressed mutant G93A superoxide dismutase protects calcineurin from inactivation. Mol Brain Res 2004; 125: 156–61
  • Jaarsma D., Haasdijk E. D., Grashorn J. A. C., Hawkins R., van Duijn W., Verspaget H. W., et al. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration and premature motor neuron death and accelerates motor neuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1. Neurobiol Dis 2000; 7: 623–43
  • Sanes J. R., Schachner M., Covault J. Expression of several adhesive macromolecules (N‐CAM, L1, J1, NILE, uvomorulin, laminin, fibronectin, and heparin sulphate proteoglycan) in embryonic, adult, and denervated adult skeletal muscle. J Cell Biol 1986; 102: 420–31
  • Cashman N. R., Covault J., Wollman R. L., Sanes J. R. Neural cell adhesion molecule in normal, denervated, and myopathic human muscle. Ann Neurol 1987; 21: 481–9
  • Tews D. S., Goebel H. H., Schneider I., Gunkel A., Stennert E., Neiss W. F. Expression profile of stress proteins, intermediate filaments, and adhesion molecules in experimentally denervated and re‐innervated rat facial muscle. Exp Neurol 1997; 146: 125–34
  • Schoser B. G., Wehling S., Blottner D. Cell death and apoptosis‐related proteins in muscle biopsies of sporadic amyotrophic lateral sclerosis and polyneuropathy. Muscle Nerve 2001; 24: 1083–9
  • Bodine S. C., Stitt T. N., Gonzalez M., Kline W. O., Stover G. L., Bauerlein R., et al. PKB/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo. Nat Cell Biol 2001; 3: 1014–9
  • Rommel C., Bodine S. C., Clarke B. A., Rossman R., Nunez L., Stitt T. N., et al. Mediation of IGF‐1‐induced skeletal myotube hypertrophy by PI(3)K/PKB/mTOR and PI(3)K/PKB/GSK3 pathways. Nat Cell Biol 2001; 3: 1009–13
  • Dobrowolny G., Giacinti C., Pelosi L., Nicoletti C., Winn N., Barberi L., et al. Muscle expression of local Igf‐1 isoform protects motor neurons in an ALS mouse model. J Cell Biol 2005; 168: 193–9
  • Kaspar B. K., Llado J., Sherkat N., Rothstein J. D., Gage F. H. Retrograde viral delivery of IGF‐1 prolongs survival in a mouse ALS model. Science 2003; 301: 839–42
  • Boillee S., Cleveland D. W. Gene therapy for ALS delivers. Trends Neurosci 2004; 27: 235–8

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.