1,654
Views
0
CrossRef citations to date
0
Altmetric
Brief Report

Effect of truncation on TRPM7 channel activity

ORCID Icon & ORCID Icon
Article: 2200874 | Received 20 Nov 2022, Accepted 04 Apr 2023, Published online: 11 Apr 2023

References

  • Nadler MJS, Hermosura MC, Inabe K, et al. LTRPC7 is a Mg·ATP-regulated divalent cation channel required for cell viability. Nature. 2001 May 31;411(6837):590–14. doi:10.1038/35079092. PubMed PMID: 11385574.
  • Runnels LW, Yue L, Clapham DE. TRP-PLIK, a bifunctional protein with kinase and ion channel activities. Science. 2001 Feb 9;291(5506):1043–1047. doi:10.1126/science.1058519. PubMed PMID: 11161216.
  • Chubanov V, Mittermeier L, Gudermann T. TRPM7 reflected in cryo-emirror. Cell Calcium. 2018 Dec;76:129–131. doi:10.1016/j.ceca.2018.11.004. PubMed PMID: 30470536.
  • Abumaria N, Li W, Clarkson AN. Role of the chanzyme TRPM7 in the nervous system in health and disease. Cell Mol Life Sci. 2019 Sep;76(17):3301–3310. doi:10.1007/s00018-019-03124-2. PubMed PMID: 31073743.
  • Abumaria N, Li W, Liu Y. TRPM7 functions in non-neuronal and neuronal systems: perspectives on its role in the adult brain. Behav Brain Res. 2018 Mar 15;340:81–86. doi:10.1016/j.bbr.2016.08.038. PubMed PMID: 27555537.
  • Desai BN, Krapivinsky G, Navarro B, et al. Cleavage of TRPM7 releases the kinase domain from the ion channel and regulates its participation in Fas-induced apoptosis. Dev Cell. 2012 Jun 12;22(6):1149–1162. doi:10.1016/j.devcel.2012.04.006. PubMed PMID: 22698280; PubMed Central PMCID: PMCPMC3397829.
  • Landman N, Jeong SY, Shin SY, et al. Presenilin mutations linked to familial Alzheimer’s disease cause an imbalance in phosphatidylinositol 4,5-bisphosphate metabolism. Proc Natl Acad Sci U S A. 2006 Dec 19;103(51):19524–19529. doi:10.1073/pnas.0604954103. PubMed PMID: 17158800; PubMed Central PMCID: PMC1748258. eng.
  • Oh HG, Chun YS, Kim Y, et al. Modulation of transient receptor potential melastatin related 7 channel by presenilins. Dev Neurobiol. 2012 Jun;72(6):865–877. doi:10.1002/dneu.22001. PubMed PMID: 22102510; PubMed Central PMCID: PMCPMC3727165.
  • Liu YQ, Chen C, Liu YL, et al. TRPM7 is required for normal synapse density, learning, and memory at different developmental stages. Cell Rep. 2018 Jun 19;23(12):3480–3491. doi:10.1016/j.celrep.2018.05.069. PubMed PMID: WOS:000435818300007; English.
  • Demeuse P, Penner R, Fleig A. TRPM7 channel is regulated by magnesium nucleotides via its kinase domain. J General Physiol. 2006 Apr;127(4):421–434. doi:10.1085/jgp.200509410. PubMed PMID: WOS:000236304000006; English.
  • Nadler MJS, Hermosura MC, Inabe K, et al. LTRPC7 is a Mg center dot ATP-regulated divalent cation channel required for cell viability. Nature. 2001 May 31;411(6837):590–595. doi:10.1038/35079092. PubMed PMID: WOS:000168982500053; English.
  • Schmidt E, Narangoda C, Norenberg W, et al. Structural mechanism of TRPM7 channel regulation by intracellular magnesium. Cellular and Molecular Life Sciences. 2022 May;79(5):ARTN 225. doi:10.1007/s00018-022-04192-7. PubMed PMID: WOS:000779754300003; English.
  • Takezawa R, Schmitz C, Demeuse P, et al. Receptor-mediated regulation of the TRPM7 channel through its endogenous protein kinase domain. Proc Natl Acad Sci USA. 2004 Apr 20;101(16):6009–6014. doi:10.1073/pnas.0307565101. PubMed PMID: WOS:000220978000061; English.
  • Chokshi R, Matsushita M, Kozak JA. Detailed examination of Mg2+ and pH sensitivity of human TRPM7 channels. Am J Physiol Cell Physiol. 2012 Apr;302(7):C1004–1011. doi:10.1152/ajpcell.00422.2011. PubMed PMID: WOS:000302342700006; English.
  • Runnels LW, Yue LX, Clapham DE. The TRPM7 channel is inactivated by PIP2 hydrolysis. Nat Cell Biol. 2002 May;4(5):329–336. doi:10.1038/ncb781. PubMed PMID: WOS:000175325100013; English.
  • Schmitz C, Perraud AL, Johnson CO, et al. Regulation of vertebrate cellular Mg2+ Homeostasis by TRPM7. Cell. 2003 Jul 25;114(2):191–200. doi:10.1016/S0092-8674(03)00556-7. PubMed PMID: WOS:000184378700009; English.
  • Matsushita M, Kozak JA, Shimizu Y, et al. Channel function is dissociated from the intrinsic kinase activity and autophosphorylation of TRPM7/ChaK1. J Biol Chem. 2005 May 27;280(21):20793–20803. doi:10.1074/jbc.M413671200. PubMed PMID: WOS:000229242000077; English.
  • Ryazanova LV, Rondon LJ, Zierler S, et al. TRPM7 is essential for Mg2+ homeostasis in mammals. Nature Communications. 2010 Nov; 1: ARTN 109 doi:10.1038/ncomms1108. PubMed PMID: WOS:000288224800007; English.
  • Jansen C, Sahni J, Suzuki S, et al. The coiled-coil domain of zebrafish TRPM7 regulates Mg center dot nucleotide sensitivity. Scientific Reports. 2016 Sep 15; 6. ARTN 33459. doi:10.1038/srep33459. PubMed PMID: WOS:000383169900001; English.
  • Monteilh-Zoller MK, Hermosura MC, Nadler MJ, et al. TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions. J Gen Physiol. 2003 Jan;121(1):49–60. doi:10.1085/jgp.20028740. PubMed PMID: 12508053; PubMed Central PMCID: PMCPMC2217320.
  • Kim BJ, Jeon JH, Kim SJ, et al. Regulation of transient receptor potential melastatin 7 (TRPM7) currents by mitochondria. Mol Cells. 2007 Jun 30;23(3):363–369. PubMed PMID: 17646711.
  • Gualdani R, Gailly P, Yuan JH, et al. A TRPM7 mutation linked to familial trigeminal neuralgia: omega current and hyperexcitability of trigeminal ganglion neurons. Proc Natl Acad Sci U S A. 2022 Sep 20;119(38):e2119630119. doi:10.1073/pnas.2119630119. PubMed PMID: 36095216; PubMed Central PMCID: PMCPMC9499596.
  • Kollewe A, Chubanov V, Tseung FT, et al. The molecular appearance of native TRPM7 channel complexes identified by high-resolution proteomics. Elife. 2021 Nov 12;10. doi:10.7554/eLife.68544. PubMed PMID: 34766907; PubMed Central PMCID: PMCPMC8616561.
  • Yee NS, Kazi AA, Yee RK. Cellular and developmental biology of TRPM7 CHannel-Kinase: implicated roles in cancer. Cells. 2014 Jul 30;3(3):751–777. doi:10.3390/cells3030751. PubMed PMID: 25079291; PubMed Central PMCID: PMCPMC4197629.
  • Cai N, Bai ZY, Nanda V, et al. Mass spectrometric analysis of trpm6 and trpm7 phosphorylation reveals regulatory mechanisms of the channel-Kinases. Scientific Reports. 2017 Feb 21;7: ARTN 42739. doi:10.1038/srep42739. PubMed PMID: WOS:000394709700001; English.
  • Valente P, Fernandez-Carvajal A, Camprubi-Robles M, et al. Membrane-tethered peptides patterned after the TRP domain (TRPducins) selectively inhibit TRPV1 channel activity. FASEB J. 2011 May;25(5):1628–1640. doi:10.1096/fj.10-174433. PubMed PMID: 21307333.
  • Xie J, Sun BN, Du JY, et al. Phosphatidylinositol 4,5-bisphosphate (PIP2) controls magnesium gatekeeper TRPM6 activity. Scientific Reports. 2011 Nov 9;1 ARTN 146doi:10.1038/srep00146. PubMed PMID: WOS:000300555700001; English.
  • Liao M, Cao E, Julius D, et al. Structure of the TRPV1 ion channel determined by electron cryo-microscopy. Nature. 2013 Dec 5;504(7478):107–112. doi:10.1038/nature12822. PubMed PMID: 24305160; PubMed Central PMCID: PMCPMC4078027.
  • Cao E, Liao M, Cheng Y, et al. TRPV1 structures in distinct conformations reveal activation mechanisms. Nature. 2013 Dec 5;504(7478):113–118. doi:10.1038/nature12823. PubMed PMID: 24305161; PubMed Central PMCID: PMCPMC4023639.
  • Duan JJ, Li ZL, Li J, et al. Structure of the mammalian TRPM7, a magnesium channel required during embryonic development. Proc Natl Acad Sci USA. 2018 Aug 28;115(35):Eb201–210. doi:10.1073/pnas.1810719115. PubMed PMID: WOS:000442861600016; English.
  • Taberner FJ, Lopez-Cordoba A, Fernandez-Ballester G, et al. The region adjacent to the C-end of the inner gate in transient receptor potential melastatin 8 (TRPM8) channels plays a central role in allosteric channel activation. J Biol Chem. 2014 Oct 10;289(41):28579–28594. doi:10.1074/jbc.M114.577478. PubMed PMID: 25157108; PubMed Central PMCID: PMCPMC4192508.
  • Rohacs T, Lopes CMB, Michailidis I, et al. Pi(4,5)P-2 regulates the activation and desensitization of TRPM8 channels through the TRP domain. Nat Neurosci. 2005 May;8(5):626–634. doi:10.1038/nn1451. PubMed PMID: WOS:000228895100023; English.
  • Wehage E, Eisfeld J, Heiner I, et al. Activation of the cation channel long transient receptor potential channel 2 (LTRPC2) by hydrogen peroxide. A splice variant reveals a mode of activation independent of ADP-ribose. J Biol Chem. 2002 Jun 28;277(26):23150–23156. doi:10.1074/jbc.M112096200. PubMed PMID: 11960981.
  • XZS X, Moebius F, Gill DL, et al. Regulation of melastatin, a TRP-related protein, through interaction with a cytoplasmic isoform. Proc Natl Acad Sci USA. 2001 Sep 11;98(19):10692–10697. doi:10.1073/pnas.191360198. PubMed PMID: WOS:000170966800037; English.
  • Chubanov V, Waldegger S, Mederos Y, et al. Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia. Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):2894–2899. doi:10.1073/pnas.0305252101. PubMed PMID: 14976260; PubMed Central PMCID: PMCPMC365716.
  • Bousova K, Zouharova M, Herman P, et al. TRPM7 N-terminal region forms complexes with calcium binding proteins CaM and S100A1. Heliyon. 2021 Dec;7(12):e08490. doi:10.1016/j.heliyon.2021.e08490. PubMed PMID: 34917797; PubMed Central PMCID: PMCPMC8645431.