Expression patterns and changes of the LCN2 gene in the testes of induced cryptorchidism and busulfan-treated mice

References

• Abella, V., Scotece, M., Conde, J., Gómez, R., Lois, A., Pino, J., et al. (2015) The potential of lipocalin-2/NGAL as biomarker for inflammatory and metabolic diseases. Biomarkers 20(8): 565–571.
   PubMed Web of Science ®Google Scholar
• Beamer, W.G., Cunliffe-Beamer, T.L., Shultz, K.L., Langley, S.H. and Roderick, T.H. (1988) Juvenile spermatogonial depletion (jsd): a genetic defect of germ cell proliferation of male mice. Biol Reprod 38(4): 899–908.
   PubMed Web of Science ®Google Scholar
• Chamindrani Mendis-Handagama, S.M.L. and Siril Ariyaratne, H.B. (2001) Differentiation of the Adult Leydig Cell Population in the Postnatal Testis 1. Biol Reprod 65(3): 660–671.
   Google Scholar
• Chen, H., Ge, R.S. and Zirkin, B.R. (2009) Leydig cells: from stem cells to aging. Mol Cell Endocrinol 306(1): 9–16.
   PubMed Web of Science ®Google Scholar
• Dutta, S., Joshi, K.R., Sengupta, P. and Bhattacharya, K. (2013) Unilateral and bilateral cryptorchidism and its effect on the testicular morphology, histology, accessory sex organs, and sperm count in laboratory mice. J Hum Reprod Sci 6(2): 106.
   Google Scholar
• Emmelot-Vonk, M.H., Verhaar, H.J., Pour, H.R. N., Aleman, A., Lock, T.M., Bosch, J.R., et al. (2008) Effect of testosterone supplementation on functional mobility, cognition, and other parameters in older men: a randomized controlled trial. Jama 299(1): 39–52.
   Google Scholar
• Flower, D.R. (1996) The lipocalin protein family: structure and function. Biochem J 318(1): 1–14.
   PubMed Web of Science ®Google Scholar
• Fujino, R.S., Tanaka, K., Morimatsu, M., Tamura, K., Kogo, H. and Hara, T. (2006) Spermatogonial cell-mediated activation of an IkappaBzeta-independent nuclear factor-kappaB pathway in Sertoli cells induces transcription of the lipocalin-2 gene. Mol Endocrinol 20(4): 904–915.
   PubMed Web of Science ®Google Scholar
• Guyonnet, B., Marot, G., Dacheux, J.L., Mercat, M.J., Schwob, S., Jaffrézic, F., et al. (2009) The adult boar testicular and epididymal transcriptomes. BMC Genomics 10(1): 369.
   PubMedGoogle Scholar
• Jin, D., Zhang, Y. and Chen, X. (2011) Lipocalin 2 deficiency inhibits cell proliferation, autophagy, and mitochondrial biogenesis in mouse embryonic cells. Mol Cell Biochem 351(1–2): 165–172.
   PubMed Web of Science ®Google Scholar
• Joel, R.Y.O.N., Bendickson, L. and Nilsen-Hamilton, M. (2002) High expression in involuting reproductive tissues of uterocalin/24p3, a lipocalin and acute phase protein. Biochem J 367(1): 271–277.
   Google Scholar
• Jung, K.Y., Yon, J.M., Lin, C., Jung, A.Y., Lee, J.G., Baek, I.J., et al. (2015a) Phospholipid hydroperoxide glutathione peroxidase is involved in the maintenance of male fertility under cryptorchidism in mice. Reprod Toxicol 57: 73–80.
   PubMed Web of Science ®Google Scholar
• Jung, S.W., Kim, H.J., Lee, B.H., Choi, S.H., Kim, H.S., Choi, Y.K., et al. (2015b) Effects of Korean Red Ginseng extract on busulfan-induced dysfunction of the male reproductive system. J Ginseng Res 39(3): 243–249.
   PubMed Web of Science ®Google Scholar
• Kehrer, J.P. (2010) Lipocalin-2: pro-or anti-apoptotic?. Cell Biol Toxicol 26(2): 83–89.
   PubMed Web of Science ®Google Scholar
• Kojima, Y., Kominami, K., Dohmae, K., Nonomura, N., Miki, T., Okuyama, A., et al. (1997) Cessation of Spermatogenesis in Juvenile Spermatogonia Depletion (jsd/jsd) Mice. Int J Urol 4(5): 500–507.
   PubMedGoogle Scholar
• Krausz, C. and Giachini, C. (2007) Genetic risk factors in male infertility. Arch Androl 53(3): 125–133.
   PubMed Web of Science ®Google Scholar
• Li, Z., Tian, J., Cui, G., Wang, M. and Yu, D. (2015) Effects of local testicular heat treatment on Leydig cell hyperplasia and testosterone biosynthesis in rat testes. Reprod Fertil Dev 28(9): 1424–1432.
   Web of Science ®Google Scholar
• Lilja, H.E., Morrison, W.A., Han, X.L., Palmer, J., Taylor, C., Tee, R., et al. (2012) An adipoinductive role of inflammation in adipose tissue engineering: key factors in the early development of engineered soft tissues. Stem Cells Dev 22(10): 1602–1613.
   Web of Science ®Google Scholar
• Lin, C.W., Tseng, S.W., Yang, S.F., Ko, C.P., Lin, C.H., Wei, L.H., et al. (2012) Role of lipocalin 2 and its complex with matrix metalloproteinase-9 in oral cancer. Oral Dis 18(8): 734–740.
   PubMed Web of Science ®Google Scholar
• Lin, H.H., Liao, C.J., Lee, Y.C., Hu, K.H., Meng, H.W. and Chu, S.T. (2011) Lipocalin-2-induced cytokine production enhances endometrial carcinoma cell survival and migration. Int J Biol Sci 7(1): 74–86.
   PubMed Web of Science ®Google Scholar
• Liu, Q., Ryon, J. and Nilsen-Hamilton, M. (1997) Uterocalin: a mouse acute phase protein expressed in the uterus around birth. Mol Reprod Dev 46(4): 507–514.
   PubMed Web of Science ®Google Scholar
• Nishimune, Y. and Tanaka, H. (2006) Infertility caused by polymorphisms or mutations in spermatogenesis-specific genes. J Androl 27(3) 326–334.
   PubMedGoogle Scholar
• O’Shaughnessy, P.J., Hu, L. and Baker, P.J. (2008) Effect of germ cell depletion on levels of specific mRNA transcripts in mouse Sertoli cells and Leydig cells. Reproduction 135(6): 839–850.
   PubMed Web of Science ®Google Scholar
• Pfaffl, M.W. (2001) A new mathematical model for relative quantification in real-time RT–PCR. Nucleic Acids Res 29(9): e45–e45.
   PubMed Web of Science ®Google Scholar
• Qi, Q.R., Zhao, X.Y., Zuo, R.J., Wang, T.S., Gu, X.W., Liu, J.L., et al. (2015) Involvement of atypical transcription factor E2F8 in the polyploidization during mouse and human decidualization. Cell Cycle 14(12): 1842–1858.
   PubMed Web of Science ®Google Scholar
• Qin, Y., Liu, L., He, Y., Wang, C., Liang, M., Chen, X., et al. (2016) Testicular busulfan injection in mice to prepare recipients for spermatogonial stem cell transplantation is safe and non-toxic. PloS One 11(2): e0148388.
   PubMed Web of Science ®Google Scholar
• Risbridger, G.P., Kerr, J.B. and De Kretser, D.M. (1981) Evaluation of Leydig cell function and gonadotropin binding in unilateral and bilateral cryptorchidism: evidence for local control of Leydig cell function by the seminiferous tubule. Biol Reprod 24(3): 534–540.
   PubMed Web of Science ®Google Scholar
• Salier, J.P., Åkerström, B., Borregaard, N. and Flower, D.R. (2004) Lipocalins in bioscience: the first family gathering. Bioessays 26(4): 456–458.
   PubMedGoogle Scholar
• Sanders, J.E., Hawley, J., Levy, W., Gooley, T., Buckner, C.D., Deeg, H.J., et al. (1996) Pregnancies following high-dose cyclophosphamide with or without high-dose busulfan or total-body irradiation and bone marrow transplantation. Blood 87(7): 3045–3052.
   PubMed Web of Science ®Google Scholar
• Sengupta, P. (2013) The laboratory rat: relating its age with human’s. Int J Prev Med 4(6): 624–630.
   PubMedGoogle Scholar
• Suzuki, K., Lareyre, J.J., Sánchez, D., Gutierrez, G., Araki, Y., Matusik, R.J., et al. (2004) Molecular evolution of epididymal lipocalin genes localized on mouse chromosome 2. Gene 339: 49–59.
   PubMed Web of Science ®Google Scholar
• Tanaka, K., Tamura, H., Tanaka, H., Katoh, M., Futamata, Y., Seki, N., et al. (2002) Spermatogonia-dependent expression of testicular genes in mice. Dev Biol 246(2): 466–479.
   PubMed Web of Science ®Google Scholar
• Tremblay, J.J. (2015) Molecular regulation of steroidogenesis in endocrine Leydig cells. Steroids 103: 3–10.
   PubMed Web of Science ®Google Scholar
• Watanabe, H., Takeo, T., Tojo, H., Sakoh, K., Berger, T., Nakagata, N., et al. (2014) Lipocalin 2 binds to membrane phosphatidylethanolamine to induce lipid raft movement in a PKA-dependent manner and modulates sperm maturation. Development 141(10): 2157–2164.
   PubMed Web of Science ®Google Scholar
• Zhang, Y., Foncea, R., Deis, J.A., Guo, H., Bernlohr, D.A. and Chen, X. (2014) Lipocalin 2 expression and secretion is highly regulated by metabolic stress, cytokines, and nutrients in adipocytes. PloS One 9(5): e96997.
   PubMed Web of Science ®Google Scholar
• Zhang, Z.W., Qiao, N., Kang, Z.L., Chen, Z.L., Hu, L.M., Yang, Z.M., et al. (2016) Copper-Induced Spermatozoa Head Malformation Is Related to Oxidative Damage to Testes in CD-1 Mice. Biol Trace Elem Res 173(2): 427–432.
   PubMed Web of Science ®Google Scholar
• Zohni, K., Zhang, X., Tan, S.L., Chan, P. and Nagano, M.C. (2012) The efficiency of male fertility restoration is dependent on the recovery kinetics of spermatogonial stem cells after cytotoxic treatment with busulfan in mice. Hum Reprod 27(1): 44–53.
   PubMed Web of Science ®Google Scholar