Can trophectoderm RNA analysis predict human blastocyst competency?

References

• Achache H, Revel A. 2006. Endometrial receptivity markers, the journey to successful embryo implantation. Hum Reprod Update. 12(6):731–746.
   PubMed Web of Science ®Google Scholar
• Armstrong S, Vail A, Mastenbroek S, Jordan V, Farquhar C. 2015. Time-lapse in the IVF-lab: how should we assess potential benefit? Hum Reprod. 30(1):3–8.
   Google Scholar
• Arriza JL, Weinberger C, Cerelli G, Glaser TM, Handelin BL, Housman DE, Evans RM. 1987. Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor. Science. 237(4812):268–275.
   PubMed Web of Science ®Google Scholar
• Ashton KA, Proietto A, Otton G, Symonds I, McEvoy M, Attia J, Gilbert M, Hamann U, Scott RJ. 2010. Polymorphisms in genes of the steroid hormone biosynthesis and metabolism pathways and endometrial cancer risk. Cancer Epidemiol. 34(3):328–337.
   PubMed Web of Science ®Google Scholar
• Assou S, Boumela I, Haouzi D, Monzo C, Dechaud H, Kadoch I-J, Hamamah S. 2012. Transcriptome analysis during human trophectoderm specification suggests new roles of metabolic and epigenetic genes. PLoS One. 7(6):e39306.
   PubMed Web of Science ®Google Scholar
• Babu K, Zhang J, Moloney S, Pleasants T, McLean CA, Phua SH, Sheppard AM. 2012. Epigenetic regulation of ABCG2 gene is associated with susceptibility to xenobiotic exposure. J Proteomics. 75(12):3410–3418.
   PubMed Web of Science ®Google Scholar
• Bagchi IC, Li Q, Cheon YP. 2001. Role of steroid hormone‐regulated genes in implantation. Ann N Y Acad Sci. 943(1):68–76.
   PubMedGoogle Scholar
• Bergh C. 2005. Single embryo transfer: a mini-review. Hum Reprod. 20(2):323–327.
   PubMed Web of Science ®Google Scholar
• Blakeley P, Fogarty NM, Del Valle I, Wamaitha SE, Hu TX, Elder K, Snell P, Christie L, Robson P, Niakan KK. 2015. Defining the three cell lineages of the human blastocyst by single-cell RNA-seq. Development. 142(18):3151–3165.
   PubMed Web of Science ®Google Scholar
• Braude PR. 1979. Control of protein synthesis during blastocyst formation in the mouse. Dev Biol. 68(2):440–452.
   PubMed Web of Science ®Google Scholar
• Brison DR. 2000. Apoptosis in mammalian preimplantation embryos: regulation by survival factors. Hum Fertil. 3(1):36–47.
   Google Scholar
• Brison DR, Houghton FD, Falconer D, Roberts SA, Hawkhead J, Humpherson PG, Lieberman BA, Leese HJ. 2004. Identification of viable embryos in IVF by non-invasive measurement of amino acid turnover. Hum Reprod. 19(10):2319–2324.
   PubMed Web of Science ®Google Scholar
• Cai C, Liu J, Wang C, Shen J. 2012. KHDC1A, a novel translational repressor, induces endoplasmic reticulum-dependent apoptosis. DNA Cell Biol. 31(9):1447–1457.
   PubMed Web of Science ®Google Scholar
• Calhaz-Jorge C, de Geyter C, Kupka MS, de Mouzon J, Erb K, Mocanu E, Motrenko T, Scaravelli G, Wyns C, Goossens V. 2016. Assisted reproductive technology in Europe, 2012: results generated from European registers by ESHRE. Hum Reprod. 31(8):1638–1652.
   Google Scholar
• Chittenden T, Flemington C, Houghton AB, Ebb RG, Gallo GJ, Elangovan B, Chinnadurai G, Lutz RJ. 1995. A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions. Embo J. 14(22):5589.
   PubMed Web of Science ®Google Scholar
• Choi Y, Kim H-R, Lim EJ, Park M, Yoon JA, Kim YS, Kim E-K, Shin J-E, Kim JH, Kwon H. 2016. Integrative analyses of uterine transcriptome and MicroRNAome reveal compromised LIF-STAT3 signaling and progesterone response in the endometrium of patients with recurrent/repeated implantation failure (RIF). PLoS One. 11(6):e0157696.
   PubMed Web of Science ®Google Scholar
• Cimadomo D, Capalbo A, Ubaldi FM, Scarica C, Palagiano A, Canipari R, Rienzi L. 2016. The impact of biopsy on human embryo developmental potential during preimplantation genetic diagnosis. Biomed Res Int, 2016.
   PubMedGoogle Scholar
• Clemente M, Lopez-Vidriero I, O’Gaora P, Mehta J, Forde N, Gutierrez-Adan A, Lonergan P, Rizos D. 2011. Transcriptome changes at the initiation of elongation in the bovine conceptus. Biol Reprod. 85(2):285–295.
   PubMed Web of Science ®Google Scholar
• Cullinan EB, Abbondanzo SJ, Anderson PS, Pollard JW, Lessey BA, Stewart CL. 1996. Leukemia inhibitory factor (LIF) and LIF receptor expression in human endometrium suggests a potential autocrine/paracrine function in regulating embryo implantation. Proc Natl Acad Sci. 93(7):3115–3120.
   PubMed Web of Science ®Google Scholar
• De Geyter C, Calhaz-Jorge C, Kupka M, Wyns C, Mocanu E, Motrenko T, Scaravelli G, Smeenk J, Vidakovic S, Goossens V. 2018. ART in Europe, 2014: results generated from European registries by ESHRE: the European IVF-monitoring Consortium (EIM) for the European Society of Human Reproduction and Embryology (ESHRE). Hum Reprod. 33(9):1586–1601.
   PubMed Web of Science ®Google Scholar
• De Neubourg D, Gerris J. 2003. Single embryo transfer–state of the art. Reprod Biomed Online. 7(6):615–622.
   PubMedGoogle Scholar
• Dickmann Z, Dey SK, Gupta JS. 1975. Steroidogenesis in rabbit preimplantation embryos. Proc Natl Acad Sci. 72(1):298–300.
   PubMed Web of Science ®Google Scholar
• El-Sayed A, Hoelker M, Rings F, Salilew D, Jennen D, Tholen E, Sirard M-A, Schellander K, Tesfaye D. 2006. Large-scale transcriptional analysis of bovine embryo biopsies in relation to pregnancy success after transfer to recipients. Physiol Genomics. 28(1):84–96.
   PubMed Web of Science ®Google Scholar
• Fagerberg L, Hallström BM, Oksvold P, Kampf C, Djureinovic D, Odeberg J, Habuka M, Tahmasebpoor S, Danielsson A, Edlund K. 2014. Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics. Mol Cell Proteomics. 13(2):397–406.
   PubMed Web of Science ®Google Scholar
• Feigelson HS, Cox DG, Cann HM, Wacholder S, Kaaks R, Henderson BE, Albanes D, Altshuler D, Berglund G, Berrino F. 2006. Haplotype analysis of the HSD17B1 gene and risk of breast cancer: a comprehensive approach to multicenter analyses of prospective cohort studies. Cancer Res. 66(4):2468–2475.
   PubMed Web of Science ®Google Scholar
• Follit JA, Tuft RA, Fogarty KE, Pazour GJ. 2006. The intraflagellar transport protein IFT20 is associated with the Golgi complex and is required for cilia assembly. Mol Biol Cell. 17(9):3781–3792.
   PubMed Web of Science ®Google Scholar
• Franasiak JM, Forman EJ, Hong KH, Werner MD, Upham KM, Treff NR, Scott RT. 2014. The nature of aneuploidy with increasing age of the female partner: a review of 15,169 consecutive trophectoderm biopsies evaluated with comprehensive chromosomal screening. Fertil Steril. 101(3):656–663. e651.
   PubMed Web of Science ®Google Scholar
• Fujii H, Tatsumi K, Kosaka K, Yoshioka S, Fujiwara H, Fujii S. 2006. Eph–ephrin A system regulates murine blastocyst attachment and spreading. Dev Dyn. 235(12):3250–3258.
   PubMed Web of Science ®Google Scholar
• Gardner DK, Balaban B. 2016. Assessment of human embryo development using morphological criteria in an era of time-lapse, algorithms and ‘OMICS’: is looking good still important? MHR Basic Sci Reprod Med. 22(10):704–718.
   Google Scholar
• Gardner DK, Schoolcraft WB. 1999. Culture and transfer of human blastocysts. Curr Opin Obstetrics Gynecology. 11(3):307–311.
   PubMed Web of Science ®Google Scholar
• Geisert R, Yelich J. 1996. Regulation of conceptus development and attachment in pigs. J Reprod Fertil Suppl. 52:133–149.
   Google Scholar
• Gilbert SF. 2000. An Introduction to Early Developmental Processes. In: Developmental Biology. 6th edition. Sunderland (MA): Sinauer Associates.
   Google Scholar
• Ham E, Cirillo V, Zanetti ME, Kuehl F. 1975. Estrogen-directed synthesis of specific prostaglandins in uterus. Proc Natl Acad Sci. 72(4):1420–1424.
   PubMed Web of Science ®Google Scholar
• Haouzi D, Dechaud H, Assou S, Monzo C, De Vos J, Hamamah S. 2011. Transcriptome analysis reveals dialogues between human trophectoderm and endometrial cells during the implantation period. Hum Reprod. 26(6):1440–1449.
   PubMed Web of Science ®Google Scholar
• Hardarson T, Ahlström A, Rogberg L, Botros L, Hillensjö T, Westlander G, Sakkas D, Wikland M. 2012. Non-invasive metabolomic profiling of Day 2 and 5 embryo culture medium: a prospective randomized trial. Hum Reprod. 27(1):89–96.
   PubMed Web of Science ®Google Scholar
• Hardwick L, Velamakanni S, Veen H. 2007. The emerging pharmacotherapeutic significance of the breast cancer resistance protein (ABCG2). Br J Pharmacol. 151(2):163–174.
   PubMed Web of Science ®Google Scholar
• Harper JC. 2018. Preimplantation genetic screening. J Med Screen. 25(1):1–5.
   PubMed Web of Science ®Google Scholar
• Harton GL, Munné S, Surrey M, Grifo J, Kaplan B, McCulloh DH, Griffin DK, Wells D, Group PP. 2013. Diminished effect of maternal age on implantation after preimplantation genetic diagnosis with array comparative genomic hybridization. Fertil Steril. 100(6):1695–1703.
   PubMed Web of Science ®Google Scholar
• Herrero J, Meseguer M. 2013. Selection of high potential embryos using time-lapse imaging: the era of morphokinetics. Fertil Steril. 99(4):1030–1034.
   PubMed Web of Science ®Google Scholar
• Holets L, Carletti M, Kshirsagar S, Christenson L, Petroff M. 2009. Differentiation-induced post-transcriptional control of B7-H1 in human trophoblast cells. Placenta. 30(1):48–55.
   PubMed Web of Science ®Google Scholar
• Holm P, Booth PJ, Callesen H. 2002. Kinetics of early in vitro development of bovine in vivo-and in vitro-derived zygotes produced and/or cultured in chemically defined or serum-containing media. Reproduction. 123(4):553–565.
   PubMed Web of Science ®Google Scholar
• Hosseini S, Dufort I, Caballero J, Moulavi F, Ghanaei H, Sirard M. 2015. Transcriptome profiling of bovine inner cell mass and trophectoderm derived from in vivo generated blastocysts. BMC Dev Biol. 15(1):49.
   PubMedGoogle Scholar
• Houghton FD. 2006. Energy metabolism of the inner cell mass and trophectoderm of the mouse blastocyst. Differentiation. 74(1):11–18.
   PubMed Web of Science ®Google Scholar
• Ing NH. 2005. Steroid hormones regulate gene expression posttranscriptionally by altering the stabilities of messenger RNAs. Biol Reprod. 72(6):1290–1296.
   PubMed Web of Science ®Google Scholar
• Iqbal K, Chitwood JL, Meyers-Brown GA, Roser JF, Ross PJ. 2014. RNA-seq transcriptome profiling of equine inner cell mass and trophectoderm. Biol Reprod. 90(3):61, 61–69.
   PubMed Web of Science ®Google Scholar
• Janvilisri T, Shahi S, Venter H, Balakrishnan L. 2005. Arginine-482 is not essential for transport of antibiotics, primary bile acids and unconjugated sterols by the human breast cancer resistance protein (ABCG2). Biochem J. 385(2):419–426.
   PubMedGoogle Scholar
• Jones GM, Cram DS, Song B, Kokkali G, Pantos K, Trounson AO. 2008. Novel strategy with potential to identify developmentally competent IVF blastocysts. Hum Reprod. 23(8):1748–1759.
   PubMed Web of Science ®Google Scholar
• Ka H, Seo H, Choi Y, Yoo I, Han J. 2018. Endometrial response to conceptus-derived estrogen and interleukin-1β at the time of implantation in pigs. J Anim Sci Biotechnol. 9(1):44.
   PubMedGoogle Scholar
• Kanehisa M, Goto S. 2000. KEGG: kyoto encyclopedia of genes and genomes. Nucleic Acids Res. 28(1):27–30.
   PubMed Web of Science ®Google Scholar
• Kawai K, Harada T, Ishikawa T, Sugiyama R, Kawamura T, Yoshida A, Tsutsumi O, Ishino F, Kubota T, Kohda T. 2018. Parental age and gene expression profiles in individual human blastocysts. Sci Rep. 8(1):2380.
   PubMedGoogle Scholar
• Kimber SJ. 2005. Leukaemia inhibitory factor in implantation and uterine biology. Reproduction. 130(2):131–145.
   PubMed Web of Science ®Google Scholar
• Kirkegaard K, Svane ASP, Nielsen JS, Hindkjær JJ, Nielsen NC, Ingerslev HJ. 2014. Nuclear magnetic resonance metabolomic profiling of Day 3 and 5 embryo culture medium does not predict pregnancy outcome in good prognosis patients: a prospective cohort study on single transferred embryos. Hum Reprod. 29(11):2413–2420.
   PubMed Web of Science ®Google Scholar
• Kirkegaard K, Villesen P, Jensen JM, Hindkjær JJ, Kølvraa S, Ingerslev HJ, Lykke-Hartmann K. 2015. Distinct differences in global gene expression profiles in non-implanted blastocysts and blastocysts resulting in live birth. Gene. 571(2):212–220.
   PubMed Web of Science ®Google Scholar
• Koo G, Conley SK, Wassif CA, Porter FD. 2010. Discordant phenotype and sterol biochemistry in Smith–lemli–opitz syndrome. Am J Med Genet Part A. 152(8):2094–2098.
   Google Scholar
• Krisher RL, Schoolcraft WB, Katz-Jaffe MG. 2015. Omics as a window to view embryo viability. Fertil Steril. 103(2):333–341.
   PubMed Web of Science ®Google Scholar
• Lamp M, Peters M, Reinmaa E, Haller-Kikkatalo K, Kaart T, Kadastik Ü, Karro H, Metspalu A, Salumets A. 2011. Polymorphisms in ESR1, ESR2 and HSD17B1 genes are associated with fertility status in endometriosis. Gynecological Endocrinol. 27(6):425–433.
   PubMed Web of Science ®Google Scholar
• Lee H-L, McCulloh DH, Hodes-Wertz B, Adler A, McCaffrey C, Grifo JA. 2015. In vitro fertilization with preimplantation genetic screening improves implantation and live birth in women age 40 through 43. J Assist Reprod Genet. 32(3):435–444.
   PubMed Web of Science ®Google Scholar
• Loutradi KE, Tarlatzis BC, Goulis DG, Zepiridis L, Pagou T, Chatziioannou E, Grimbizis GF, Papadimas I, Bontis I. 2006. The effects of sperm quality on embryo development after intracytoplasmic sperm injection. J Assist Reprod Genet. 23(2):69–74.
   PubMed Web of Science ®Google Scholar
• Maglott D, Ostell J, Pruitt KD, Tatusova T. 2005. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 33(suppl_1):D54–D58.
   PubMedGoogle Scholar
• Majumdar G, Majumdar A, Verma IC, Upadhyaya KC. 2017. Relationship between morphology, euploidy and implantation potential of cleavage and blastocyst stage embryos. J Hum Reprod Sci. 10(1):49.
   PubMedGoogle Scholar
• Margalioth EJ, Ben-Chetrit A, Gal M, Eldar-Geva T. 2006. Investigation and treatment of repeated implantation failure following IVF-ET. Hum Reprod. 21(12):3036–3043.
   PubMed Web of Science ®Google Scholar
• Martinez-Arguelles DB, Papadopoulos V. 2010. Epigenetic regulation of the expression of genes involved in steroid hormone biosynthesis and action. Steroids. 75(7):467–476.
   PubMed Web of Science ®Google Scholar
• Matsumoto H. 2017. Molecular and cellular events during blastocyst implantation in the receptive uterus: clues from mouse models. J Reprod Dev.
   Web of Science ®Google Scholar
• Meseguer M, Herrero J, Tejera A, Hilligsøe KM, Ramsing NB, Remohí J. 2011. The use of morphokinetics as a predictor of embryo implantation. Hum Reprod. 26(10):2658–2671.
   PubMed Web of Science ®Google Scholar
• Meseguer M, Rubio I, Cruz M, Basile N, Marcos J, Requena A. 2012. Embryo incubation and selection in a time-lapse monitoring system improves pregnancy outcome compared with a standard incubator: a retrospective cohort study. Fertil Steril. 98(6):1481–1489. e1410.
   PubMed Web of Science ®Google Scholar
• Moayeri M, Saeidi H, Modarresi MH, Hashemi M. 2016. The effect of preimplantation genetic screening on implantation rate in women over 35 years of age. Cell J (Yakhteh). 18(1):13.
   PubMed Web of Science ®Google Scholar
• Munne S, Marquez C, Reing A, Garrisi J, Alikani M. 1998. Chromosome abnormalities in embryos obtained after conventional in vitro fertilization and intracytoplasmic sperm injection. Fertil Steril. 69(5):904–908.
   PubMed Web of Science ®Google Scholar
• Nagaoka SI, Hassold TJ, Hunt PA. 2012. Human aneuploidy: mechanisms and new insights into an age-old problem. Nat Rev Genet. 13(7):493–504.
   PubMed Web of Science ®Google Scholar
• Niakan KK, Han J, Pedersen RA, Simon C, Pera RAR. 2012. Human pre-implantation embryo development. Development. 139(5):829–841.
   PubMed Web of Science ®Google Scholar
• Noci I, Fuzzi B, Rizzo R, Melchiorri L, Criscuoli L, Dabizzi S, Biagiotti R, Pellegrini S, Menicucci A, Baricordi OR. 2005. Embryonic soluble HLA-G as a marker of developmental potential in embryos. Hum Reprod. 20(1):138–146.
   PubMed Web of Science ®Google Scholar
• Ntostis P, Agiannitopoulos K, Tsaousis G, Pantos K, Lamnissou K. 2015. Evidence for association of the rs605059 polymorphism of HSD17B1 gene with recurrent spontaneous abortions. J Maternal-Fetal Neonatal Med. 28(18):2250–2253.
   PubMed Web of Science ®Google Scholar
• Ntostis P, Carter D, Iles D, Huntriss J, Tzetis M, Miller D. 2017. Potential sperm contributions to the murine zygote predicted by in silico analysis. Reproduction. 154(6):777–788.
   PubMed Web of Science ®Google Scholar
• Nygren KG, Andersen AN. 2001. Assisted reproductive technology in Europe, 1997. Results generated from European registers by ESHRE. European IVF-Monitoring Programme (EIM), for the European Society of Human Reproduction and Embryology (ESHRE). Hum Reprod. 16(2):384–391.
   PubMed Web of Science ®Google Scholar
• Ozawa M, Sakatani M, Yao J, Shanker S, Yu F, Yamashita R, Wakabayashi S, Nakai K, Dobbs KB, Sudano MJ. 2012. Global gene expression of the inner cell mass and trophectoderm of the bovine blastocyst. BMC Dev Biol. 12(1):33.
   PubMedGoogle Scholar
• Pal A, Mehn D, Molnar E, Gedey S, Meszaros P, Nagy T, Glavinas H, Janaky T, Von Richter O, Bathori G. 2007. Cholesterol potentiates ABCG2 activity in a heterologous expression system: improved in vitro model to study function of human ABCG2. J Pharmacol Exp Ther. 321(3):1085–1094.
   PubMed Web of Science ®Google Scholar
• Parks JC, McCallie BR, Janesch AM, Schoolcraft WB, Katz-Jaffe MG. 2011. Blastocyst gene expression correlates with implantation potential. Fertil Steril. 95(4):1367–1372.
   PubMed Web of Science ®Google Scholar
• Payne D, Flaherty SP, Barry MF, Matthews CD. 1997. Preliminary observations on polar body extrusion and pronuclear formation in human oocytes using time-lapse video cinematography. Hum Reprod. 12(3):532–541.
   PubMed Web of Science ®Google Scholar
• Pierre A, Gautier M, Callebaut I, Bontoux M, Jeanpierre E, Pontarotti P, Monget P. 2007. Atypical structure and phylogenomic evolution of the new eutherian oocyte-and embryo-expressed KHDC1/DPPA5/ECAT1/OOEP gene family. Genomics. 90(5):583–594.
   PubMed Web of Science ®Google Scholar
• Pribenszky C, Mátyás S, Kovács P, Losonczi E, Zádori J, Vajta G. 2010. Pregnancy achieved by transfer of a single blastocyst selected by time-lapse monitoring. Reprod Biomed Online. 21(4):533–536.
   PubMed Web of Science ®Google Scholar
• Pusateri A, Rothschild MF, Warner C, Ford S. 1990. Changes in morphology, cell number, cell size and cellular estrogen content of individual littermate pig conceptuses on days 9 to 13 of gestation. J Anim Sci. 68(11):3727–3735.
   PubMed Web of Science ®Google Scholar
• Raziel A, Friedler S, Schachter M, Kasterstein E, Strassburger D, Ron-El R. 2002. Increased frequency of female partner chromosomal abnormalities in patients with high-order implantation failure after in vitro fertilization. Fertil Steril. 78(3):515–519.
   PubMed Web of Science ®Google Scholar
• Revil T, Gaffney D, Dias C, Majewski J, Jerome-Majewska LA. 2010. Alternative splicing is frequent during early embryonic development in mouse. BMC Genomics. 11(1):399.
   PubMedGoogle Scholar
• Riley P, Anaon-Cartwight L, Cross JC. 1998. The Hand1 bHLH transcription factor is essential for placentation and cardiac morphogenesis. Nat Genet. 18(3):271–275.
   PubMed Web of Science ®Google Scholar
• Robinson L, Gallos ID, Conner SJ, Rajkhowa M, Miller D, Lewis S, Kirkman-Brown J, Coomarasamy A. 2012. The effect of sperm DNA fragmentation on miscarriage rates: a systematic review and meta-analysis. Hum Reprod. 27(10):2908–2917.
   PubMed Web of Science ®Google Scholar
• Scott RT, Upham KM, Forman EJ, Zhao T, Treff NR. 2013. Cleavage-stage biopsy significantly impairs human embryonic implantation potential while blastocyst biopsy does not: a randomized and paired clinical trial. Fertil Steril. 100(3):624–630.
   PubMed Web of Science ®Google Scholar
• Seli E, Sakkas D, Scott R, Kwok SC, Rosendahl SM, Burns DH. 2007. Noninvasive metabolomic profiling of embryo culture media using Raman and near-infrared spectroscopy correlates with reproductive potential of embryos in women undergoing in vitro fertilization. Fertil Steril. 88(5):1350–1357.
   PubMed Web of Science ®Google Scholar
• Sendler E, Johnson GD, Mao S, Goodrich RJ, Diamond MP, Hauser R, Krawetz SA. 2013. Stability, delivery and functions of human sperm RNAs at fertilization. Nucleic Acids Res. gkt132.
   PubMed Web of Science ®Google Scholar
• Shakiba N, White CA, Lipsitz YY, Yachie-Kinoshita A, Tonge PD, Hussein SM, Puri MC, Elbaz J, Morrissey-Scoot J, Li M. 2015. CD24 tracks divergent pluripotent states in mouse and human cells. Nat Commun, 6.
   PubMed Web of Science ®Google Scholar
• Shemesh M, Milaguir F, Ayalon N, Hansel W. 1979. Steroidogenesis and prostaglandin synthesis by cultured bovine blastocysts. J Reprod Fertil. 56(1):181–185.
   PubMedGoogle Scholar
• Steptoe PC, Edwards RG. 1978. Birth after the reimplantation of a human embryo. Lancet. 312(8085):366.
   Google Scholar
• Turpeenniemi-Hujanen T, Feinberg RF, Kauppila A, Puistola U. 1995. Extracellular matrix interactions in early human embryos: implications for normal implantation events. Fertil Steril. 64(1):132–138.
   PubMed Web of Science ®Google Scholar
• Twisk M, Mastenbroek S, van Wely M, Heineman MJ, Van der Veen F, Repping S. 2006. Preimplantation genetic screening for abnormal number of chromosomes (aneuploidies) in in vitro fertilisation or intracytoplasmic sperm injection. Cochrane Database Syst Rev. (1):1465–1858. DOI:10.1002/14651858.CD005291.pub2.
   Google Scholar
• Van Blerkom J, Davis P, Alexander S. 2001. A microscopic and biochemical study of fragmentation phenotypes in stage-appropriate human embryos. Hum Reprod. 16(4):719–729.
   PubMed Web of Science ®Google Scholar
• Vergouw CG, Botros LL, Roos P, Lens JW, Schats R, Hompes PGA, Burns DH, Lambalk CB. 2008. Metabolomic profiling by near-infrared spectroscopy as a tool to assess embryo viability: a novel, non-invasive method for embryo selection. Hum Reprod. 23(7):1499–1504.
   PubMed Web of Science ®Google Scholar
• Wilmoth T, Koch J, Smith D, Wilson M. 2010. Estradiol-17β alters trophectoderm proliferation in pig embryos. J Anim Vet Adv. 9(4):782–786.
   Google Scholar
• Wong CC, Loewke KE, Bossert NL, Behr B, De Jonge CJ, Baer TM, Pera RAR. 2010. Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage. Nat Biotechnol. 28(10):1115–1121.
   PubMed Web of Science ®Google Scholar
• Yang Z, Zhang J, Salem SA, Liu X, Kuang Y, Salem RD, Liu J. 2014. Selection of competent blastocysts for transfer by combining time-lapse monitoring and array CGH testing for patients undergoing preimplantation genetic screening: a prospective study with sibling oocytes. BMC Med Genomics. 7(1):38.
   PubMedGoogle Scholar
• Yu M, Feng R, Sun X, Wang H, Wang H, Sang Q, Jin L, He L, Wang L. 2014. Polymorphisms of pentanucleotide repeats (tttta) n in the promoter of CYP11A1 and their relationships to polycystic ovary syndrome (PCOS) risk: a meta-analysis. Mol Biol Rep. 41(7):4435–4445.
   PubMed Web of Science ®Google Scholar