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Articles

A comparison of proliferation levels in normal skin, physiological scar and keloid tissue

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Pages 122-128 | Received 25 Aug 2021, Accepted 08 Dec 2021, Published online: 29 Dec 2021

References

  • Marneros AG, Krieg T. Keloids-clinical diagnosis, pathogenesis, and treatment options. J Dtsch Dermatol Ges. 2004;2(11):905–913.
  • Jaloux C, Bertrand B, Degardin N, et al. Keloid scars (part II): treatment and prevention. Ann Chir Plast Esthet. 2017;62(1):87–96.
  • Sun Y, Liu WZ, Liu T, et al. Signaling pathway of MAPK/erk in cell proliferation, differentiation, migration, senescence and apoptosis. J Recept Signal Transduct Res. 2015;35(6):600–604.
  • Kurtzeborn K, Kwon HN, Kuure S. MAPK/erk signaling in regulation of renal differentiation. Int J Mol Sci. 2019;20(7):1779.
  • Zhang MZ, Dong XH, Guan EL, et al. A comparison of apoptosis levels in keloid tissue, physiologicla scars and normal skin. Am J Transl Res. 2017;9(12):5548–5557.
  • Ogawa R. Keloid and hypertrophic scars are the result of chronic inflammation in the reticular dermis. Int J Mol Sci. 2017;18(3):606.
  • Kassi K, Kouame K, Kouassi A, et al. Quality of life in black African patients with keloid scars. Dermatol Reports. 2020;12(2):8312.
  • Lee HJ, Jang YJ. Recent understandings of biology, prophylaxis and treatment strategies for hypertrophic scars and keloids. Int J Mol Sci. 2018;19(3):711.
  • Bai Y, Zhang Q, Su Y, et al. Modulation of the proliferation/apoptosis balance of vascular smooth muscle cells in atherosclerosis by lncRNA-MEG3 via regulation of miR-26a/Smad1 axis. Int Heart J. 2019;60(2):444–450.
  • Schutte B, Ramaekers FC. Molecular switches that govern the balance between proliferation and apoptosis. Prog Cell Cycle Res. 2000;4:207–217.
  • Si L, Zhang M, Guan E, et al. Resveratrol inhibits proliferation and promotes apoptosis of keloid fibroblasts by targeting HIF-1α. J Plast Surg Hand Surg. 2020;54(5):290–296.
  • Potter DA, Veitch D, Johnston GA. Scarring and wound healing. Br J Hosp Med. 2019;80(11):C166–C171.
  • Chen ZY, Yu XF, Huang JQ, et al. The mechanisms of beta-catenin on keloid fibroblast cells proliferation and apoptosis. Eur Rev Med Pharmacol Sci. 2018;22(4):888–895.
  • Meng X, Shi Y, Xiang X, et al. Influence of miR-101 on proliferation of liver cancer cells through the MAPK/ERK signaling pathway. Oncol Lett. 2020;19(2):1310–1316.
  • Zhao LJ, Wang L, Ren H, et al. Hepatitis C virus E2 protein promotes human hepatoma cell proliferation through the MAPK/ERK signaling pathway via cellular receptors. Exp Cell Res. 2005;305(1):23–32.
  • Jia H, Dilger P, Bird C, et al. IL-27 promotes proliferation of human leukemic cell lines through the MAPK/ERK signaling pathway and suppresses sensitivity to chemotherapeutic drugs. J Interferon Cytokine Res. 2016;36(5):302–316.
  • Dziemidowicz M, Bonda TA, Litvinovich S, et al. The role of interleukin-6 in intracellular signal transduction after chronic β-adrenergic stimulation in mouse myocardium. Arch Med Sci. 2019;15(6):1565–1575.
  • Ono K, Han J. The p38 signal transduction pathway: activation and function. Cell Signal. 2000;12(1):1–13.
  • Zhang Z, Yi P, Tu C, et al. Curcumin inhibits ERK/c-Jun expressions and phosphorylation against endometrial carcinoma. Biomed Res Int. 2019;2019:8912961.
  • Liang Z, Chi YJ, Lin GQ, et al. MiRNA-26a promotes angiogenesis in a rat model of cerebral infarction via PI3K/AKT and MAPK/ERK pathway. Eur Rev Med Pharmacol Sci. 2018;22(11):3485–3492.
  • Cardano M, Tribioli C, Prosperi E. Targeting proliferating cell nuclear antigen (PCNA) as an effective strategy to inhibit tumor cell proliferation. Curr Cancer Drug Targets. 2020;20(4):240–252.
  • Horsfall AJ, Abell AD, Bruning JB. Targeting PCNA with peptide mimetics for therapeutic purposes. Chembiochem. 2020;21(4):442–450.
  • Daian T, Ohtsuru A, Rogounovitch T, et al. Insulin-like growth factor-I enhances transforming growth factor-beta-induced extracellular matrix protein production through the P38/activating transcription factor-2 signaling pathway in keloid fibroblasts. J Invest Dermatol. 2003;120(6):956–962.
  • Marfil V, Blazquez M, Serrano F, et al. Growth-promoting and tumourigenic activity of c-Myc is suppressed by hhex. Oncogene. 2015;34(23):3011–3022.
  • Kawashima F, Saito K, Kurata H, et al. c-Jun is differentially expressed in embryonic and adult neural precursor cells. Histochem Cell Biol. 2017;147(6):721–731.
  • Meyer AE, Furumo Q, Stelloh C, et al. Loss of Fbxw7 triggers mammary tumorigenesis associated with E2F/c-Myc activation and Trp53 mutation. Neoplasia. 2020;22(11):644–658.
  • Verhoeven Y, Tilborghs S, Jacobs J, et al. The potential and controversy of targeting STAT family members in cancer. Semin Cancer Biol. 2020;60:41–56.

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