A bioconvergence study on platinum-free concurrent chemoradiotherapy for the treatment of HPV-negative head and neck carcinoma

References

• Johnson DE, Burtness B, Leemans CR, et al. Head and neck squamous cell carcinoma. Nat Rev Dis Primers. 2020;6(1):92. doi:10.1038/s41572-020-00224-3.
   PubMed Web of Science ®Google Scholar
• Mehanna H, Paleri V, West CML, et al. Head and neck cancer - Part 1: epidemiology, presentation, and prevention. BMJ. 2010;341:c4684. doi:10.1136/bmj.c4684.
   PubMed Web of Science ®Google Scholar
• McDermott JD, Bowles DW. Epidemiology of head and neck squamous cell carcinomas: impact on staging and prevention strategies. Curr. Treat. Options Oncol. 2019;20(5):43. doi:10.1007/s11864-019-0650-5.
   PubMed Web of Science ®Google Scholar
• Mody MD, Rocco JW, Yom SS, et al. Head and neck cancer. Lancet. 2021;398(10318):2289–2299. doi:10.1016/S0140-6736(21)01550-6.
   PubMed Web of Science ®Google Scholar
• Haddad RI, Hicks WL, Hitchcock YJ, et al. NCCN guidelines version 1.2023 head and neck cancers continue NCCN guidelines panel disclosures. 2022.
   Google Scholar
• Pignon J-P, Le Maître A, Maillard E, MACH-NC Collaborative Group., et al. Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): an update on 93 randomised trials and 17,346 patients. Radiother Oncol. 2009;92(1):4–14. doi:10.1016/j.radonc.2009.04.014.
   PubMed Web of Science ®Google Scholar
• Blanchard P, Baujat B, Holostenco V, et al. Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): a comprehensive analysis by tumour site. Radiother Oncol. 2011;100(1):33–40. doi:10.1016/j.radonc.2011.05.036.
   PubMed Web of Science ®Google Scholar
• Lacas B, Carmel A, Landais C, et al. Meta-analysis of chemotherapy in head and neck cancer (mach-NC): an update on 107 randomized trials and 19,805 patients, on behalf of MACH-NC group. Radiother Oncol. 2021;156:281–293. doi:10.1016/j.radonc.2021.01.013.
   PubMed Web of Science ®Google Scholar
• de Roest RH, van der Heijden M, Wesseling FWR, et al. Disease outcome and associated factors after definitive platinum based chemoradiotherapy for advanced stage HPV-negative head and neck cancer. Radiother Oncol. 2022;175:112–121. doi:10.1016/j.radonc.2022.08.013.
   PubMed Web of Science ®Google Scholar
• Van den Bosch L, van der Schaaf A, van der Laan HP, et al. Comprehensive toxicity risk profiling in radiation therapy for head and neck cancer: a new concept for individually optimised treatment. Radiother Oncol. 2021;157:147–154. doi:10.1016/j.radonc.2021.01.024.
   PubMed Web of Science ®Google Scholar
• Cui L, Her S, Borst GR, et al. Radiosensitization by gold nanoparticles: will they ever make it to the clinic? Radiother Oncol. 2017;124(3):344–356. doi:10.1016/j.radonc.2017.07.007.
   PubMed Web of Science ®Google Scholar
• Dasari S, Tchounwou PB. Cisplatin in cancer therapy: molecular mechanisms of action. Eur J Pharmacol. 2014;740:364–378. doi:10.1016/j.ejphar.2014.07.025.
   PubMed Web of Science ®Google Scholar
• Rosa S, Connolly C, Schettino G, et al. Biological mechanisms of gold nanoparticle radiosensitization. Cancer Nanotechnol. 2017;8(1):2. doi:10.1186/s12645-017-0026-0.
   PubMed Web of Science ®Google Scholar
• Bilynsky C, Millot N, Papa A-L. Radiation nanosensitizers in cancer therapy-from preclinical discoveries to the outcomes of early clinical trials. BioengTranslMed. 2022;7:e10256. doi:10.1002/btm2.10256.
   Google Scholar
• Wu Y, Zhu K, Zhang X, et al. Emerging plasmonic nanoparticles and their assemblies for cancer radiotherapy. Adv Drug Deliv Rev. 2023; 194:114710. doi:10.1016/j.addr.2023.114710.
   PubMed Web of Science ®Google Scholar
• Domingues C, Santos A, Alvarez-Lorenzo C, et al. Where is nano today and where is it headed? A review of nanomedicine and the dilemma of nanotoxicology. ACS Nano. 2022;16(7):9994–10041. doi:10.1021/acsnano.2c00128.
   PubMed Web of Science ®Google Scholar
• Cassano D, Mapanao A-K, Summa M, et al. Biosafety and biokinetics of noble metals: the impact of their chemical nature. ACS Appl Bio Mater. 2019;2(10):4464–4470. doi:10.1021/acsabm.9b00630.
   PubMedGoogle Scholar
• Mapanao AK, Giannone G, Summa M, et al. Biokinetics and clearance of inhaled gold ultrasmall-in-nano architectures. Nanoscale Adv. 2020;2(9):3815–3820. doi:10.1039/d0na00521e.
   PubMed Web of Science ®Google Scholar
• Zamborlin A, Ermini ML, Summa M, et al. The fate of intranasally instilled silver nanoarchitectures. Nano Lett. 2022;22(13):5269–5276. doi:10.1021/acs.nanolett.2c01180.
   PubMed Web of Science ®Google Scholar
• Mapanao AK, Santi M, Voliani V. Combined chemo-photothermal treatment of three-dimensional head and neck squamous cell carcinomas by gold nano-architectures. J Colloid Interface Sci. 2021;582(Pt B):1003–1011. doi:10.1016/j.jcis.2020.08.059.
   PubMedGoogle Scholar
• Mapanao AK, Santi M, Faraci P, et al. Endogenously triggerable ultrasmall-in-nano architectures: targeting assessment on 3D pancreatic carcinoma spheroids. ACS Omega. 2018;3(9):11796–11801. doi:10.1021/acsomega.8b01719.
   PubMed Web of Science ®Google Scholar
• Armanetti P, Pocoví-Martínez S, Flori A, et al. Dual photoacoustic/ultrasound multi-parametric imaging from passion fruit-like nano-architectures. Nanomedicine. 2018;14(6):1787–1795. doi:10.1016/j.nano.2018.05.007.
   PubMed Web of Science ®Google Scholar
• Mapanao AK, Che PP, Sarogni P, et al. Tumor grafted - chick chorioallantoic membrane as an alternative model for biological cancer research and conventional/nanomaterial-based theranostics evaluation. Expert Opin Drug Metab Toxicol. 2021;17(8):947–968. doi:10.1080/17425255.2021.1879047.
   PubMed Web of Science ®Google Scholar
• Che PP, Mapanao AK, Gregori A, et al. Biodegradable ultrasmall-in-nano architectures loaded with cisplatin prodrug in combination with ionizing radiation induces DNA damage and apoptosis in pancreatic ductal adenocarcinoma. Cancers. 2022;14(12):3034. doi:10.3390/cancers14123034.
   PubMed Web of Science ®Google Scholar
• Kleibeuker EA, Ten Hooven MA, Castricum KC, et al. Optimal treatment scheduling of ionizing radiation and sunitinib improves the antitumor activity and allows dose reduction. Cancer Med. Med2015;4(7):1003–1015. doi:10.1002/cam4.441.
   PubMed Web of Science ®Google Scholar
• Sarogni P, Mapanao AK, Marchetti S, et al. A standard protocol for the production and bioevaluation of ethical in vivo models of HPV-negative head and neck squamous cell carcinoma. ACS Pharmacol Transl Sci. 2021;4(3):1227–1234. doi:10.1021/acsptsci.1c00083.
   PubMedGoogle Scholar
• Sarogni P, Mapanao AK, Gonnelli A, et al. Chorioallantoic membrane tumor models highlight the effects of cisplatin compounds in oral carcinoma treatment. IScience. 2022;25(3):103980. doi:10.1016/j.isci.2022.103980.
   PubMed Web of Science ®Google Scholar
• Fogliata A, Nicolini G, Clivio A, et al. Dosimetric evaluation of acuros XB advanced dose calculation algorithm in heterogeneous media. Radiat Oncol. 2011;6(1):82. doi:10.1186/1748-717X-6-82.
   PubMedGoogle Scholar
• Sarogni P, Zamborlin A, Mapanao AK, et al. Hyperthermia reduces irradiation-induced tumor repopulation in an in vivo pancreatic carcinoma model. AdvBiol. 2023; 7(10):2200229. doi:10.1002/adbi.202200229.
   Google Scholar
• Fischer D, Fluegen G, Garcia P, et al. The CAM model-Q&a with experts. Cancers. 2022;15(1):191. doi:10.3390/cancers15010191.
   PubMed Web of Science ®Google Scholar
• DiBartolo D, Carpenter TJ, Santoro JP, et al. Novel VMAT planning technique improves dosimetry for head and neck cancer patients undergoing definitive chemoradiotherapy. Int J Radiat Oncol Biol Phys. 2022;112(5):e33. doi:10.1016/j.ijrobp.2021.12.077.
   Web of Science ®Google Scholar
• Mapanao AK, Sarogni P, Santi M, et al. Pro-apoptotic and size-reducing effects of protein corona-modulating nano-architectures enclosing platinum prodrug in in vivo oral carcinoma. Biomater Sci. 2022;10(21):6135–6145. doi:10.1039/d2bm00994c.
   PubMed Web of Science ®Google Scholar
• Santi M, Mapanao AK, Cassano D, et al. Endogenously-activated ultrasmall-in-nano therapeutics: assessment on 3D head and neck squamous cell carcinomas. Cancers . 2020;12(5):1063. doi:10.3390/cancers12051063.
   PubMed Web of Science ®Google Scholar
• Russo E, Accorona R, Iocca O, et al. Does tumor volume have a prognostic role in oropharyngeal squamous cell carcinoma? A systematic review and meta-analysis. Cancers. 2022;14(10):2465. doi:10.3390/cancers14102465.
   PubMed Web of Science ®Google Scholar
• Piccolo O, Lincoln JD, Melong N, et al. Radiation dose enhancement using gold nanoparticles with a diamond linear accelerator target: a multiple cell type analysis. Sci Rep. 2022;12(1):1559. doi:10.1038/s41598-022-05339-z.
   PubMed Web of Science ®Google Scholar
• Popovtzer A, Mizrachi A, Motiei M, et al. Actively targeted gold nanoparticles as novel radiosensitizer agents: an in vivo head and neck cancer model. Nanoscale. 2016;8(5):2678–2685.
   PubMed Web of Science ®Google Scholar