198
Views
1
CrossRef citations to date
0
Altmetric
Research Paper

Elevations in serum brain-derived neurotrophic factor following occupational heat stress are not influenced by age or common chronic disease

, , , , , , & show all
Pages 454-464 | Received 17 Nov 2022, Accepted 30 Jan 2023, Published online: 23 Feb 2023

References

  • Watts N, Amann M, Arnell N, et al. The 2020 report of the lancet countdown on health and climate change: responding to converging crises. The Lancet. 2021;397:129–170.
  • Habibi P, Moradi G, Dehghan H, et al. The impacts of climate change on occupational heat strain in outdoor workers: a systematic review. Urban Clim. 2021;36:100770.
  • Ioannou LG, Foster J, Morris NB, et al. Occupational heat strain in outdoor workers: A comprehensive review and meta-analysis. Temperature. 2022;9(1):67–102. https://doi.org/10.1080/23328940.2022.2030634
  • Meade RD, Lauzon M, Poirier MP, et al. An evaluation of the physiological strain experienced by electrical utility workers in North America. J Occup Environ Hyg. 2015;12(10):708–720.
  • Flouris AD, Dinas PC, Ioannou LG, et al. Workers‘ health and productivity under occupational heat strain: a systematic review and meta-analysis. Lancet Planet Health. 2018;2(12):e521–e531.
  • Sheridan SC, Allen MJ. Changes in the frequency and intensity of extreme temperature events and human health concerns. Current Climate Change Reports. 2015;1(3):155–162.
  • Xiang J, Hansen A, Pisaniello D, et al. Extreme heat and occupational heat illnesses in South Australia, 2001–2010. Occup Environ Med. 2015;72(8):580–586.
  • McCormick JJ, King KE, Notley SR, McCormick JJ, King KE, Notley SR, et al. Exercise in the heat induces similar elevations in serum irisin in young and older men despite lower resting irisin concentrations in older adults. J Therm Biol. 2022;104:103189.
  • KE K, JJ M, SR N, et al. Serum klotho concentrations in young and older men during prolonged exercise in temperate and hot conditions. Curr Aging Sci [Internet]. 2022 [cited 2022 May 3]; Available from: https://doi.org/10.2174/1874609815666220304200939.
  • Buselli R, Veltri A, Baldanzi S, et al. Plasma Brain-Derived Neurotrophic Factor (BDNF) and serum cortisol levels in a sample of workers exposed to occupational stress and suffering from Adjustment Disorders. Brain Behav. 2019;9(7):e01298.
  • Colucci-D’Amato L, Speranza L, Volpicelli F. Neurotrophic Factor BDNF, Physiological Functions and Therapeutic Potential in Depression, Neurodegeneration and Brain Cancer. Int J Mol Sci. 2020;21(20):7777.
  • Walsh JJ, Tschakovsky ME. Exercise and circulating BDNF: mechanisms of release and implications for the design of exercise interventions. Appl Physiol Nutr Metab. 2018;43(11):1095–1104.
  • Dinoff A, Herrmann N, Swardfager W, et al. The effect of acute exercise on blood concentrations of brain-derived neurotrophic factor in healthy adults: a meta-analysis. Eur J Neurosci. 2017;46(1):1635–1646.
  • Kerschensteiner M, Gallmeier E, Behrens L, et al. Activated human t cells, b cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: a neuroprotective role of inflammation? J Exp Med. 1999;189(5):865–870.
  • Chauhan NR, Kumar R, Gupta A, et al. Heat stress induced oxidative damage and perturbation in BDNF/ERK1/2/CREB axis in hippocampus impairs spatial memory. Behav Brain Res. 2021;396:112895.
  • King MA, Clanton TL, Laitano O. Hyperthermia, dehydration, and osmotic stress: unconventional sources of exercise-induced reactive oxygen species. Am J Physiol-Regul Integr Comp Physiol. 2016;310(2):R105–R114.
  • Notley SR, Akerman AP, Friesen BJ, et al. Heat Tolerance and Occupational Heat Exposure Limits in Older Men with and without Type 2 Diabetes or Hypertension. Med Sci Sports Exerc. 2021;53(10):2196–2206.
  • Goekint M, Roelands B, Heyman E, et al. Influence of citalopram and environmental temperature on exercise-induced changes in BDNF. Neurosci Lett. 2011;494(2):150–154.
  • Rasmussen P, Brassard P, Adser H, et al. Evidence for a release of brain-derived neurotrophic factor from the brain during exercise. Exp Physiol. 2009;94(10):1062–1069.
  • Matthews VB, Åström M-B, Chan MHS, et al. Brain-derived neurotrophic factor is produced by skeletal muscle cells in response to contraction and enhances fat oxidation via activation of AMP-activated protein kinase. Diabetologia. 2009;52(7):1409–1418.
  • Wright HE, McLellan TM, Larose J, et al. Are circulating cytokine responses to exercise in the heat augmented in older men? Appl Physiol Nutr Metab. 2014;39(2):117–123.
  • D’souza AW, Notley SR, Kenny GP. The Relation between Age and Sex on Whole-Body Heat Loss during Exercise-Heat Stress. Med Sci Sports Exerc. 2020;52(10):2242–2249.
  • Tapia-Arancibia L, Aliaga E, Silhol M, et al. New insights into brain BDNF function in normal aging and Alzheimer disease. Brain Res Rev. 2008;59(1):201–220.
  • Krabbe KS, Nielsen AR, Krogh-Madsen R, et al. Brain-derived neurotrophic factor (BDNF) and type 2 diabetes. Diabetologia. 2007;50(2):431–438.
  • Prigent-Tessier A, Quirié A, Maguin-Gaté K, et al. Physical training and hypertension have opposite effects on endothelial brain-derived neurotrophic factor expression. Cardiovasc Res. 2013;100(3):374–382.
  • Pouvreau C, Dayre A, Butkowski EG, et al. Inflammation and oxidative stress markers in diabetes and hypertension. J Inflamm Res. 2018;11:61–68.
  • Notley SR, Poirier MP, Sigal RJ, et al. Exercise Heat Stress in Patients With and Without Type 2 Diabetes. JAMA. 2019;322(14):1409–1411.
  • Akerman AP, Notley SR, Sigal RJ, et al. Impact of uncomplicated controlled hypertension on thermoregulation during exercise-heat stress. J Hum Hypertens. 2021;35(10):880–883.
  • Kenny GP, Groeller H, McGinn R, et al. Age, human performance, and physical employment standards. Appl Physiol Nutr Metab. 2016;41(6 (Suppl. 2)):S92–S107.
  • McCormick JJ, King KE, Notley SR, McCormick JJ, King KE, Notley SR, et al. The serum irisin response to prolonged physical activity in temperate and hot environments in older men with hypertension or type 2 diabetes. J Therm Biol. 2022;110:103344.
  • Kenny GP, Vierula M, Maté J, et al. A Field Evaluation of the Physiological Demands of Miners in Canada’s Deep Mechanized Mines. J Occup Environ Hyg. 2012;9(8):491–501.
  • Meade RD, Lauzon M, Poirier MP, et al. The physical demands of electrical utilities work in North America. J Occup Environ Hyg. 2016;13(1):60–70.
  • Kenny GP, Thermometry JO. Calorimetry, and Mean Body Temperature during Heat Stress. Compr Physiol [Internet]. John Wiley & Sons, Ltd; 2013 [cited 2022 Nov 26]. p. 1689–1719. Available from: https://onlinelibrary.wiley.com/doi/abs/10.1002/cphy.c130011.
  • Yarrow JF, White LJ, McCoy SC, et al. Training augments resistance exercise induced elevation of circulating brain derived neurotrophic factor (BDNF). Neurosci Lett. 2010;479(2):161–165.
  • Walsh JJ, Bentley RF, Gurd BJ, et al. Short-Duration Maximal and Long-Duration Submaximal Effort Forearm Exercise Achieve Elevations in Serum Brain-Derived Neurotrophic Factor. Front Physiol. 2017;8:746.
  • Hayek LE, Khalifeh M, Zibara V, et al. Lactate Mediates the Effects of Exercise on Learning and Memory through SIRT1-Dependent Activation of Hippocampal Brain-Derived Neurotrophic Factor (BDNF). J Neurosci. 2019;39(13):2369–2382.
  • Ohko H, Umemoto Y, Sakurai Y, et al. The effects of endurance exercise combined with high-temperature head-out water immersion on serum concentration of brain-derived neurotrophic factor in healthy young men. International Journal of Hyperthermia. 2021;38(1):1077–1085.
  • Collins CW, Shute RJ, Heesch MWS, et al. The effect of environmental temperature on exercise-dependent release of brain-derived neurotrophic factor. Temperature. 2017;4(3):305–313. https://doi.org/10.1080/23328940.2017.1328304
  • Lommatzsch M, Zingler D, Schuhbaeck K, et al. The impact of age, weight and gender on BDNF levels in human platelets and plasma. Neurobiol Aging. 2005;26(1):115–123.
  • Ziegenhorn AA, Schulte-Herbrüggen O, Danker-Hopfe H, et al. Serum neurotrophins—A study on the time course and influencing factors in a large old age sample. Neurobiol Aging. 2007;28(9):1436–1445.
  • Kaltsatou A, Notley SR, Kenny GP. Effects of exercise-heat stress on circulating stress hormones and interleukin-6 in young and older men. Temperature. 2020;7(4):389–393. https://doi.org/10.1080/23328940.2020.1768032
  • Lang X, Zhao N, He Q, et al. Treadmill exercise mitigates neuroinflammation and increases BDNF via activation of SIRT1 signaling in a mouse model of T2DM. Brain Res Bull. 2020;165:30–39.
  • Nemcsik J, László A, Lénárt L, et al. Hyperthymic affective temperament and hypertension are independent determinants of serum brain-derived neurotrophic factor level. Ann Gen Psychiatry. 2016;15(1):17.
  • Kenny GP, Yardley JE, Martineau L, et al. Physical work capacity in older adults: implications for the aging worker. Am J Ind Med. 2008;51(8):610–625.
  • Kaiser AB, Zhang N, Der Pluijm WV. Global Prevalence of Type 2 Diabetes over the Next Ten Years (2018-2028). Diabetes. 2018;67(Supplement_1):202–LB.
  • Mills KT, Stefanescu A, He J. The global epidemiology of hypertension. Nat Rev Nephrol. 2020;16(4):223–237.
  • Baker LD, Frank LL, Foster-Schubert K, et al. Aerobic Exercise Improves Cognition for Older Adults with Glucose Intolerance, A Risk Factor for Alzheimer’s Disease. J Alzheimers Dis. 2010;22(2):569–579
  • Erickson KI, Voss MW, Prakash RS, et al. Exercise training increases size of hippocampus and improves memory. Proc Natl Acad Sci U S A. 2011;108(7):3017–3022.
  • Szuhany KL, Bugatti M, Otto MW. A meta-analytic review of the effects of exercise on brain-derived neurotrophic factor. J Psychiatr Res. 2015;60:56–64.
  • Molinari C, Morsanuto V, Ruga S, et al. The Role of BDNF on Aging-Modulation Markers. Brain Sci. 2020;10(5):285.
  • Watson P, Shirreffs SM, Maughan RJ. Blood-brain barrier integrity may be threatened by exercise in a warm environment. Am J Physiol-Regul Integr Comp Physiol. 2005;288(6):R1689–R1694.
  • Waterhouse J, Drust B, Weinert D, et al. The Circadian Rhythm of Core Temperature: origin and some Implications for Exercise Performance. Chronobiol Int. 2005;22:207–225.
  • Cain SW, Chang A-M, Vlasac I, et al. Circadian Rhythms in Plasma Brain-derived Neurotrophic Factor Differ in Men and Women. J Biol Rhythms. 2017;32:75–82.
  • Schoeller DA. Changes in total body water with age. Am J Clin Nutr. 1989;50:1176–1181. discussion 1231-1235
  • Low S, Ng TP, Lim CL, et al. Higher ratio of extracellular water to total body water was associated with reduced cognitive function in type 2 diabetes. J Diabetes. 2021;13:222–231.
  • Cianci R, Citro F, Migneco A, et al. Body fluid compartments in hypertension. Eur Rev Med Pharmacol Sci. 2006;10:75–78.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.