Physiological importance of aquaporin water channels

References

• Verkman AS, Mitra AK. Structure and function of aquaporin water channels. Am J Physiol 2000; 278: F13–28.
   PubMed Web of Science ®Google Scholar
• Ishibashi K, Kuwahara M, Sasaki S. Molecular biology of aquaporins. Rev Physiol Biochem Pharmacol 2000; 141: 1–32.
   PubMedGoogle Scholar
• Borgnia M, Nielsen S, Engel A, Agre P. Cellular and molecular biology of the aquaporin water channels. Annu Rev Biochem 1999; 68: 425–58.
   PubMed Web of Science ®Google Scholar
• Sansom MS, Law RJ. Membrane proteins: Aquaporins - channels without ions. Curr Biol 2001; 11: R71–3.
   Google Scholar
• Berry V, Francis P, Kaushal S, Moore A, Bhattacharya S. Missense mutations in MIP underlie autosomal dominant 'polymorphic' and lamellar cataracts linked to 12q. Nat Genet 2000; 25: 15–7.
   PubMed Web of Science ®Google Scholar
• Shiels A, Bassnett S. Mutations in the founder of the MIP gene family underlie cataract development in the mouse. Nat Genet 1996; 12: 212–5.
   PubMed Web of Science ®Google Scholar
• Preston GM, Smith BL, Zeidel ML, Moulds JJ, Agre P. Mutations in aquaporin-1 in phenotypically normal humans without functional CHIP water channels. Science 1994; 265: 1585–7.
   PubMed Web of Science ®Google Scholar
• King LS, Choi M, Fernandez PC, Cartron JP, Agre P. Defective urinary-concentrating ability due to a complete deficiency of aquaporin-1. N Engl J Med 2001; 345: 175–9.
   PubMed Web of Science ®Google Scholar
• Ma T, Yang B, Gillespie A, Carlson EJ, Epstein CJ, Verkman AS. Severely impaired urinary concentrating ability in transgenic mice lacking aquaporin-1 water channels. J Biol Chem 1998; 273: 4296–9.
   PubMed Web of Science ®Google Scholar
• Morello JP, Bichet DG. Nephrogenic diabetes insipidus. Annu Rev Physiol 2001; 63: 607–30.
   PubMed Web of Science ®Google Scholar
• Deen PM, Verkijk MA, Knoers NV, Wieringa B, Monnens LA, van Os CH, et al. Requirement of human renal water channel aquaporin-2 for vasopressin-dependent concentration of urine. Science 1994; 264: 92–5.
   PubMed Web of Science ®Google Scholar
• Kwon TH, Hager H, Nejsum LN, Andersen ML, Frokiaer J, Nielsen S. Physiology and pathophysiology of renal aquaporins. Semin Nephrol 2001; 21: 231–8.
   PubMed Web of Science ®Google Scholar
• Agre P. Aquaporin water channels in kidney. J Am Soc Nephrol 2000; 11: 764–77.
   Google Scholar
• Ma T, Song Y, Yang B, Gillespie A, Carlson EJ, Epstein CJ, et al. Nephrogenic diabetes insipidus in mice deficient in aquaporin-3 water channels. Proc Nat! Acad Sci USA 2000; 97: 4386–91.
   PubMed Web of Science ®Google Scholar
• Ma T, Yang B, Gillespie A, Carlson EJ, Epstein CJ, Verkman AS. Generation and phenotype of a transgenic knock-out mouse lacking the mercurial-insensitiw water channel aquaporin-4. J Clin Invest 1997; 100: 957–62.
   Google Scholar
• Yang B, Ma T, Verkman AS. Erythrocyte water permeability and renal function in double knockout mice lacking aqua-porin-1 and aquaporin-3. J Biol Chem 2001; 276: 624–8.
   PubMed Web of Science ®Google Scholar
• Schnermann J, Chou CL, Ma T, Traynor T, Knepper MA, Verkman AS. Defective proximal tubular fluid reabsorption in transgenic aquaporin-1 null mice. Proc Nat! Acad Sci USA 1998; 95: 9660–4.
   PubMedGoogle Scholar
• Spring KR. Routes and mechanisms of fluid transport by epithelia. Annu Rev Physiol 1998; 60:105–19.
   Google Scholar
• Vallon V, Verkman AS, Schnermann J. Luminal hypotonicity in proximal tubules of aquaporin-1 knockout mice. Am J Physiol 2000; 278: F1030–3.
   Google Scholar
• Chou CL, Knepper MA, Van Hoek AN, Brown D, Ma T, Verkman AS. Reduced water permeability and altered ultra-structure in thin descending limb of Henle in aquaporin-1 null mice. J Clin Invest 1999; 103: 491–6.
   PubMedGoogle Scholar
• Pallone TL, Edwards A, Ma T, Silldorff E, Verkman AS. Requirement of aquaporin-1 for NaC1 driven water transport across descending vasa recta. J Clin Invest 2000; 105: 215–22.
   Google Scholar
• Tamarappoo BK, Verkman AS. Defective trafficking of AQP2 water channels in nephrogenic diabetes insipidus and correction by chemical chaperones. J Clin Invest 1998; 101: 2257–63.
   PubMed Web of Science ®Google Scholar
• Yang B, Gillespie A, Carlson EJ, Epstein CJ, Verkman AS. Early neonatal mortality in a transgenic AQP2 knock-in model of nephrogenic diabetes insipidus. J Biol Chem 2001; 276: 2775–9.
   PubMed Web of Science ®Google Scholar
• Chou CL, Ma T, Yang B, Knepper MA, Verkman AS. Four-fold reduction in water permeability in inner medullary collecting duct of aquaporin4 knockout mice. Am J Physiol 1998; 274: C549–54.
   Google Scholar
• Verbavatz JM, Ma T, Gobin R, Verkman AS. Absence of orthogonal arrays in kidney, brain and muscle from transgenic knockout mice lacking water channel aquaporin-4. J. Cell Sci 1997; 110: 2855–60.
   Google Scholar
• Ma T, Song Y, Gillespie A, Carlson EJ, Epstein CJ, Verkman AS. Defective secretion of saliva in transgenic mice lacking aquaporin-5 water channels. J Biol Chem 1999; 274: 20071–4.
   PubMed Web of Science ®Google Scholar
• Krane CM, Melvin JE, Nguyen HV, Richardson L, Towne JE, Doetschman T, et al. Salivary acinar cells from aquaporin 5-deficient mice have decreased membrane water permeability and altered cell volume regulation. J Biol Chem 2001; 276: 23413–20.
   PubMed Web of Science ®Google Scholar
• Wang, KS, Komar AR, Ma T, Filiz F, McLeroy J, Hoda K, et al. Gastric acid secretion in aquaporin-4 knockout mice. Am J Physiol 2000; 279: G448–53.
   Google Scholar
• Wang KS, Ma T, Filiz F, Verkman AS, Bastidas JA. Colon water transport in transgenic mice lacking aquaporin-4 water channels. Am J Physiol 2000; 279: G463–70.
   Google Scholar
• Ma T, Jayaraman, S, Wang, KS, Bastidas JA, Verkman AS. Defective dietary fat processing in transgenic mice lacking aquaporin-1 water channels. Am J Physiol 2000; 280: C126–34.
   Google Scholar
• Manley GT, Fujimura M, Ma T, Noshita N, Filiz F, Bollen A, Chan P, Verkman AS. Aquaporin-4 deletion in mice reduces brain edema following acute water intoxication and ischemic stroke. Nat Med 2000; 6: 159–63.
   PubMed Web of Science ®Google Scholar
• Li J, Verkman AS. Impaired hearing in mice lacking aquaporin-4 water channels. J Biol Chem 2001; 276: 31233–7.
   PubMed Web of Science ®Google Scholar
• Li J, Patil RV, Verkman AS. Mildly abnormal retinal function in transgenic mice lacking aquaporin-4 water channels. Invest Ophthalmol Vis Sci 2002; 43: 573–9.
   PubMed Web of Science ®Google Scholar
• Solenov El, Vetrivel L, Oshio K, Manley GT, Verkman AS. Optical measurement of swelling and water transport in spinal cord slices from aquaporin null mice. J Neurosci Meth 2001; 113: 85–90.
   Google Scholar
• Oshio K, Shields S, Basbaum A, Verkman AS, Manley GT. Reduced pain sensation and impaired nociception in mice lacking the aquaporin-1 membrane water channel. J Am Soc Nephrol 2001; 12: 20A–21A.
   Google Scholar
• Bai CX, Fukuda N, Song Y., Ma T, Matthay MA, Verkman AS. Role of aquaporin water channels in lung fluid transport. phenotype analysis of aquaporin 1 and 4 knockout mice. J Clin Invest 1999; 103: 555–61.
   PubMed Web of Science ®Google Scholar
• Ma T, Fukuda N, Song Y, Matthay MA, Verkman AS. Lung fluid transport in aquaporin-5 knockout mice. J Clin Invest 2000; 105: 93–100.
   PubMed Web of Science ®Google Scholar
• Song Y, Ma T, Matthay MA, Verkman AS. Role of aquaporin-4 in airspace-to-capillary water permeability in intact mouse lung measured by a novel gravimetric method. J Gen Physiol 2000; 115: 17–27.
   Google Scholar
• Song Y, Fukuda N, Bai C, Ma T, Matthay MA, Verkman AS. Role of aquaporins in alveolar fluid clearance in neonatal and adult lung, and in edema formation following lung injury. J Physiol 2000; 525: 771–9.
   PubMed Web of Science ®Google Scholar
• Moore M, Ma T, Yang B, Verkman AS. Tear secretion by lacrimal glands in transgenic mice lacking water channels AQP1, AQP3, AQP4 and AQP5. Exp Eye Res 2000; 70: 557–62.
   PubMed Web of Science ®Google Scholar
• Yang B, Fukuda N, van Hoek AN, Matthay MA, Ma T, Verkman AS. Carbon dioxide permeability of aquaporin-1 measured in erythrocytes and lung of aquaporin-1 null mice and in reconstituted proteoliposomes. J Biol Chem 2000; 275: 2686–92.
   Web of Science ®Google Scholar
• Song Y, Yang B, Matthay MA, Ma T, Verkman AS. Role of aquaporin water channels in pleural fluid dynamics. Am J Physiol 2000; 279: C1744–50.
   Google Scholar
• Yang B, Folkesson HG, Yang J, Matthay MA, Ma T, Verkman AS. Reduced water permeability of the peritoneal barrier in aquaporin-1 knockout mice. Am J Physiol1999; 276: C76–81.
   Google Scholar
• Song Y, Jayaraman S, Yang B, Matthay MA, Verkman AS. Role of aquaporin water channels in airway fluid transport, humidification and surface liquid hydration J Gen Physiol 2001; 117: 573–82.
   Google Scholar
• Krane CM, Fortner CN, Hand AR, McGraw DW, Lorenz JN, Wert SE, et al. Aquaporin 5-deficient mouse lungs are hyperresponsive to cholinergic stimulation. Proc Nat! Acad Sci USA 2001; 98: 14114–9.
   PubMed Web of Science ®Google Scholar
• Song Y, Verkman AS. Aquaporin-5 dependent fluid secretion in airway submucosal glands. J Biol Chem 2001; 276: 41288–92.
   PubMed Web of Science ®Google Scholar
• Zhang D., Vetrivel L, Verkman AS. Aquaporin deletion in mice reduces intraocular pressure and aqueous fluid produc-tion. J Gen Physiol 2002; 119: 561–9.
   PubMedGoogle Scholar
• Thiagarajah JR, Verkman AS. Aquaporin deletion in mice reduces corneal water permeability and delays restoration of transparency after swelling. J Biol Chem 2002; 277: 19139–44.
   PubMed Web of Science ®Google Scholar
• Ma T, Hara M, Sougrat R, Verbavatz JM, Verkman, AS. Impaired stratum corneum hydration in mice lacking epider-mal water channel aquaporin-3. J Biol Chem 2002; 277: 17147–53.
   PubMed Web of Science ®Google Scholar
• Yang B, Verbavatz JM, Song Y, Manley G, Vetrivel L, Kao WM, et al. Skeletal muscle function and water transport in aquaporin-4 deficient mice. Am J Physic)/ 2000; 278: C1008–15.
   Google Scholar