Antiatherogenic effects of 17β-estradiol and 17α-estradiol and its derivative J811 in cholesterol-fed rabbits with thyroid inhibition

References

• Stampfer MJ, Colditz GA, Willett WC, et al. Postmenopausal estrogen therapy and cardio-vascular disease. Ten-year follow-up from the Nurses' Health Study. N Engl J Med 1991;325: 756–62
   Google Scholar
• Sullivan JM. Hormone replacement therapy and cardiovascular disease: the human model. Br J Obstet Gynaecol 1996;103:59–67
   PubMedGoogle Scholar
• Nathan L, Chaudhuri G. Estrogens and athero-sclerosis. Ann Rev Pharmacol Toxicol 1997;37: 477–515
   PubMed Web of Science ®Google Scholar
• Punnonen R, Jokela H, Aine R, et al. Impaired ovarian function and risk factors for athero-sclerosis in premenopausal women. Maturitas 1997;27:231–8
   PubMed Web of Science ®Google Scholar
• Clarkson TB, Anthony MS, Klein KP. Hormone replacement therapy and coronary artery athero-sclerosis: the monkey model. Br J Obstet Gynaecol 1996;103:53–8
   Google Scholar
• Muscat Baron Y, Brincat M, Galea R. Carotid artery wall thickness in women treated with hormone replacement therapy. Maturitas 1997; 27:47–53
   Google Scholar
• Haarbo J. Impact of hormone replacement therapy on serum lipids, lipoproteins, body com-position, and atherosclerosis: clinical and experi-mental studies. Dan Med Bull 1994;41:412–22
   PubMed Web of Science ®Google Scholar
• Sulistiyani, Adelman SJ, Chandrasekaran A, et al. Effect of 17a-dihydroequilin sulfate, a con-jugated equine estrogen, and ethynylestradiol on atherosclerosis in cholesterol-fed rabbits. Arterioscler Thromb Vasc Biol 1995;15:837–46
   PubMed Web of Science ®Google Scholar
• Washburn SA, Honore EK, Cline JM, et al. Effects of 17a-dihydroequilenin sulfate on atherosclerotic male and female rhesus monkeys. Am J Obstet Gynecol 1996;175:341–51
   PubMed Web of Science ®Google Scholar
• Hanke H, Hanke S, Bruck B, et al. Inhibition of the protective effect of estrogen by progesterone in experimental atherosclerosis. Atherosclerosis 1996;121:129–38
   PubMed Web of Science ®Google Scholar
• Haarbo J, Christiansen C. The impact of female sex hormones on secondary prevention of atherosclerosis in ovariectomized cholesterol-fed rabbits. Atherosclerosis 1996;123:139–44
   PubMed Web of Science ®Google Scholar
• Haarbo J, Leth-Espensen P, Stender S, et al. Estrogen monotherapy and combined estrogen—progestogen replacement therapy attenuate aortic accumulation of cholesterol in ovari-ectomized cholesterol-fed rabbits. J Clin Invest 1991;87:1274–9
   PubMed Web of Science ®Google Scholar
• Haarbo J, Svendsen OL, Christiansen C. Proges-togens do not affect aortic accumulation of cholesterol in ovariectomized cholesterol-fed rabbits. Circ Res 1992;70:1198–202
   Google Scholar
• Haarbo J, Hormone replacement therapy and cardiovascular disease: the rabbit model. Br J Obstet Gynaecol 1996;103:49–52
   PubMedGoogle Scholar
• Haarbo J, Hansen BF, Christiansen C. Hormone replacement therapy prevents coronary artery disease in ovariectomized cholesterol-fed rabbits. Acta Pathol Microbiol Immunol Scand 1991; 99:721–7
   Google Scholar
• Salonen JT, Nyyssönen K, Salonen R, et al. Lipo-protein oxidation and progression of carotid atherosclerosis. Circulation 1997;95:840–5
   PubMed Web of Science ®Google Scholar
• Ruehlmann DO, Mann GE. Actions of estrogens on vascular endothelial and smooth-muscle cells. Biochem Soc Trans 1997;25:40–5
   PubMed Web of Science ®Google Scholar
• Wiseman H, O'Reilly J. Estrogens as antioxidant cardioprotectants. Biochem Soc Trans 1997;25: 54–9
   PubMed Web of Science ®Google Scholar
• Haarbo J, Nielsen LB, Stender S, et al. Aortic per-meability to LDL during estrogen therapy. Arterioscler Thromb 1994;14:243–7
   PubMedGoogle Scholar
• Steinberg D, Parthasarathy S, Carew TE, et al. Modifications of low-density lipoprotein that increase its atherogenicity. New Engl J Med 1989;320:915–24
   PubMed Web of Science ®Google Scholar
• Daugherty A, Roselaar SE. Lipoprotein oxida-tion as a mediator of atherogenesis: insights from pharmacological studies. Cardiovasc Res 1995; 29:297–311
   PubMed Web of Science ®Google Scholar
• Mooradian AD. Antioxidant properties of steroids. J Steroid Biochem Mol Biol 1993;45: 509–11
   PubMed Web of Science ®Google Scholar
• Römer W, Oettel M, Droescher P, et al. Novel `scavestrogens' and their radical scavenging effects, iron-chelating and total antioxidative activities: 48,9-dehydro derivatives of 17a-estradiol and 170-estradiol. Steroids 1997;62: 304–10
   Google Scholar
• Oettel M, Römer W, Heller R. The therapeutic potential of scavestrogens. Eur J Obstet Gynecol Reprod Biol 1996;65:153
   Web of Science ®Google Scholar
• Seeger H, Mueck AO, Oettel M, et al. Calcium antagonistic effect of 17a-estradiol derivatives: in vitro examinations. Gynecol Endocrinol 1999; 13:246–8
   PubMed Web of Science ®Google Scholar
• Holm P, Korsgaard N, Shalmi M, et al. Signifi-cant reduction of the antiatherogenic effect of estrogen by long-term inhibition of nitric oxide synthesis in cholesterol-clamped rabbits. J Clin Invest 1997;100:821–8
   PubMed Web of Science ®Google Scholar
• Spritz N. Atherosclerosis and menopause. Mod Treat 1968;5:581–6
   PubMedGoogle Scholar
• Libert 0, Rogg-Efront C. Experimental athero-sclerosis and hyperlipidemia in rats and rabbits: influence of some alimentary fats. J Atheroscl Res 1962;2: 186–98
   Google Scholar
• Trillo A. Effect of thiouracil upon canine arterial elastic tissue. Atherosclerosis 1975;22–369–77
   Google Scholar
• Lowry OH, Rosenbrough NJ, Farr AL, et al. Protein measurement with the Folin phenol reagent. J Biol Chem 1951;193:265–75
   PubMed Web of Science ®Google Scholar
• Lipid Research Clinics Program. Lipid and Lipo-protein Analysis. Manual of Laboratory Opera-tions, I. USA Department of Health Education and Welfare, DHEW publication no. (NIH) 75–628. Bethesda, MD: National Heart and Lung Institute, 1974
   Google Scholar
• Chinellato A, Ragazzi E, Petrelli L, et al. Effect of cholesterol-supplemented diet in heritable hyper-lipidemic Yoshida rats. Atherosclerosis 1994; 106:51–63
   PubMed Web of Science ®Google Scholar
• Hanke H, Hanke S, Finking G, et al. Different effects of estrogen and progesterone on experi-mental atherosclerosis in female versus male rabbits. Circulation 1996;94:175–81
   PubMed Web of Science ®Google Scholar
• Bush TL, Barrett-Connor E, Cowan LD, et al. Cardiovascular mortality and noncontraceptive use of estrogen in women: results from the Lipid Research Clinics Program Follow-up Study. Circulation 1987;75:1102–9
   PubMed Web of Science ®Google Scholar
• Kushugava RS, Levis DS, Carey DS, McHill HC. Effects of estrogen and progesterone on plasma lipoprotein and experimental atherosclerosis in the baboon (Pavio sp.). Arterioscler Thromb 1991;11:23–31
   PubMedGoogle Scholar
• Henriksson P, Stamberger M, Eriksson M, et al. Oestrogen-induced changes in lipoprotein meta-bolism: role in prevention of atherosclerosis in the cholesterol-fed rabbit. Eur J Clin Invest 1989;19:395–403
   PubMed Web of Science ®Google Scholar
• Wagner JD, Clarkson TB, St Clair RW, et al. Estrogen and progesterone replacement therapy reduces low density lipoprotein accumulation in the coronary arteries of surgically postmeno-pausal cynomolgus monkeys. J Clin Invest 1991; 88:1995–2002
   PubMed Web of Science ®Google Scholar
• Hough JL, Zilversmit DB. Effect of 1713-estradiol on aortic cholesterol content and metabolism in cholesterol-fed rabbits. Arteriosclerosis 1986;6: 57–63
   PubMedGoogle Scholar
• Williams RJ, Motteram JM, Sharp CH, et al. Dietary vitamin-E and attenuation of early lesions development in modified Watanabe rabbits. Atherosclerosis 1992;94:153–9
   PubMed Web of Science ®Google Scholar
• Teoh MK, Chong JMK, Mohamed J, et al. Pro-tection by tocotrienol against hypercholestero-laemia and atheroma. Med J Malaysia 1994; 49:255–62
   PubMedGoogle Scholar
• Wieseman SA, Mathot JNNJ, de Fouw NJ, et al. Dietary non-tocopherol antioxidants present in extra virgin olive oil increase the resistance of low density lipoproteins to oxidation in rabbits. Atherosclerosis 1996;120:15–23
   PubMed Web of Science ®Google Scholar
• Borkhelm I, Henriksson-Freyschuss A, Breuer 0, et al. The antioxidant butylated hydroxytoluene protects against atherosclerosis. Arterioscler Thromb 1991;11:15–22
   Google Scholar
• Tawara K, Ishichara M, Ogawa H, et al. Effect of probucol, pantethine and their combinations on serum lipoprotein metabolism and on the inci-dence of atheromatous lesions in the rabbit. Jpn J Pharmacol 1986;41:211–22
   PubMedGoogle Scholar
• Shaish A, Daughtery A, O'Sullivan F, et al. Beta-carotene inhibits atherosclerosis in hyperchol-esterinemic rabbits. J Clin Invest 1995;96: 2075–82
   Google Scholar