Protection of bronchoalveolar macrophages by granulocyte-macrophage colony-stimulating factor against dexamethasone suppression of fungicidal activity for Aspergillus fumigatus conidia

References

• Anderson RJ, Schaffer LA, Olin DB, Eickhoff C. Infectious risk factors in the immunosuppressed host. Am J Med 1973; 54:453–460.
   PubMed Web of Science ®Google Scholar
• Gustafson TL, Schaffner W, Lavely GB, Stratton CW, Johnson HK, Hutcherson RH. Invasive aspergillosis in renal transplant recipients: correlation with corticosteriod therapy. J Infect Dis 1983; 148: 230–238.
   PubMed Web of Science ®Google Scholar
• Walsh TJ, Mendelsohn G. Invasive aspergillosis complicating Cushing's syndrome. Arch Intern Med 1981; 141: 1227–1228.
   PubMed Web of Science ®Google Scholar
• Graham S, Tucker WS. Opportunistic infections in endogenous Cushing's syndrome. Ann Intern Med 1984; 101:334–338.
   PubMed Web of Science ®Google Scholar
• Schaffner A. Therapeutic concentrations of glucosteroids sup-press the antimicrobial activity of human macrophages without impairing their responsiveness to gamma interferon. J Gun Invest 1985; 76: 1755–1764.
   PubMed Web of Science ®Google Scholar
• Roilides E, Blake C, Holmes A, Pizzo PA, Walsh TJ. Granulocyte-macrophage colony-stimulating factor and inter-feron-gamma prevent dexamethasone-inducedimmunosuppres-sion of antifungal monocyte activity against Aspergillus fumigatus hyphae. J Med Vet Mycol 1996; 34: 63–69.
   Google Scholar
• Michaliszyn E, Senechal S, Martel P, deRepentigny L. Lack of involvement of nitric oxide in killing Aspergillus fumigatus
   Google Scholar
• Robertson MD, Kerr KM, Seaton A. Killing of Aspergillus fumigatus spores by human lung macrophages: a paradoxical effect of heat-labile serum components. J Med Vet Mycol 1989; 27: 295–302.
   Google Scholar
• Sugar AM, Brummer E, Stevens DA. Murine pulmonary macrophages: evaluation of lung lavage fluids, miniaturized monolayers, and candidacidal activity. Am Rev Respir Dis 1983; 127: 110–112.
   Google Scholar
• Washburn RG, Gallin JI, Bennett JE. Oxidative killing of Aspergillus fumigatus by parallel MPO-dependent and indepen-dent pathways. Infect Immun 1987; 55: 2088–2092.
   Google Scholar
• Brummer E, Morozumi PA, Vo PT, Stevens DA. Protection against pulmonary blastomycosis: adoptive transfer with T lymphocytes, but not serum, from resistant mice. Cell Immunol 1982; 73: 349–359.
   PubMed Web of Science ®Google Scholar
• Schaffner A, Douglas H, Braude A. Selective protection against conidia by mononuclear and against mycelia by polymorpho-nuclear phagocytes in resistance to Aspergillus. J Clin Invest 1982; 69: 617–631.
   Google Scholar
• Levitz SM, Diamond RD. Mechanisms of resistance of Aspergillus fumigatus conidia to killing by neutrophils in vitro. J Infect Dis 1985; 152: 33–43.
   PubMed Web of Science ®Google Scholar
• Schaffner A, Douglas H, Braude Al, Davis CE. Killing of Aspergillus spores depends on the anatomical source. Infect Immun 1983; 42: 1109–1115.
   PubMed Web of Science ®Google Scholar
• Kozel TR, Wilson MA, Farrell TP, Levitz SM. Activation of C3 and binding to Aspergillus fumigatus conidia and hyphae. Infect Immun 1989; 57: 3412–3417.
   PubMed Web of Science ®Google Scholar
• Condino-Neto A, Whitney C, Newburger PE. Dexamethasone but not indomethacin inhibits human phagocyte nicotinamide adenine dinucleotide phosphate oxidase activity by down regulating expression of genes encoding oxidase components. J Immunol 1998; 161: 4960–4967.
   Google Scholar
• Natarajan U, Randhawa N, Brummer E, Stevens DA. Effect of granulocyte-macrophage colony-stimulating factor on candida-cidal activity of neutrophils, monocytes or monocyte-derived macrophages and synergy with fluconazole. J Med Microbiol 1998; 47: 359–363.
   PubMed Web of Science ®Google Scholar
• Vora S, Purimetla N, Brummer E, Stevens DA. Activity of voriconazole, a new triazole, combined with neutrophils or monocytes against Candida albicans: effect of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor. Antimicrob Agents Chemother 1998; 42:907–910.
   PubMed Web of Science ®Google Scholar
• Vora S, Chauhan S, Brummer E, Stevens DA. Activity of voriconazole combined with neutrophils or monocytes against Aspergillus fumigatug effect of granulocyte colony-stimulating factor and granulocyte macrophage colony-stimulating factor. Antimicrob Agents Chemother 1998; 42: 2299–2303.
   PubMed Web of Science ®Google Scholar
• Lim TK, Chen G-H, McDonald RA, Toews GB. Granulocyte-macrophage colony-stimulating factor overrides the immuno-suppressive function of corticosteroids on rat pulmonary dentritic cells. Stem Cells 199614: 292–299.
   Google Scholar
• Munck A, Mendel DB, Smith LI, Orti E. Glucocorticoid receptors and actions. Am Rev Respir Dis 1990;141:52–S10.
   Google Scholar
• Payvar F, Wrange O, Carlstedt-Duke J, Obret S, Gustafason JA, Yamamoto KR. Purified glucocorticoid receptors bind selec-tively in vitro to a cloned DNA fragment whose transcription is regulated by glucocorticoids in vivo. Proc Natl Acad Sci USA 1981; 78: 6628–6632.
   Google Scholar
• Auphan N, Di Donato JA, Rosette C, Helmberg A, Karin M. Immunosuppression by glucocorticoids: inhibition of NF-kB activity through induction of IkB synthesis. Science 1995; 270: 286–290.
   PubMed Web of Science ®Google Scholar
• Rosen RL, Winestock KD, Chen G, Liu X, Henninghausen L, Finbloom DS. Granulocyte-macrophage colony-stimulating factor preferentially activates 94 kD STAT5a and an 80 kD STAT5a isoform in human blood monocytes. Blood 1996; 8& 1206–1214.
   Google Scholar
• Al-Shami A, Mahanna W, Nacake PH. Granulocyte-macro-phage colony-stimulating factor activated signaling pathways in human neutrophils. Selective activation of JAK2, STAT5b, and STAT3. J Biol Chem 1998; 273: 1058–1063.
   Google Scholar
• Linden M, Brattsand R. Effect of a corticosteroid, budenoside, on alveolar macrophage and blood monocyte secretion of cytokines: differential sensitivity of GM-CSF, IL-113 and IL-6. Pul Pharmaco11994; 7: 43–47.
   PubMedGoogle Scholar
• Joyce DA, Steer JH, Abraham LJ. Glucocorticoid modulation of human monocyte/macrophage function: control of TNF-alpha secretion. Inflamm Res 1997; 46: 447–451.
   Google Scholar
• Alwawi WY, Beyhum HN, Rahme AA, Rieder MJ. Regulation of cytokine and cytokine receptor expression by glucocorticoids. J Leuk Biol 1996; 60: 563–572.
   PubMed Web of Science ®Google Scholar
• Moynihan JA, Callahan TA, Kelley SP, Campbell LM. Adrenal hormone modulation of type 1 and type 2 cytokine production by spleen cells: dexamethasone and dehydroepiandrosterone suppress interleukin-2, interleukin-4, and interferon gamma production in vitro. Cell Immunol 1998; 184: 58–64.
   PubMed Web of Science ®Google Scholar
• Ala-Aoukaty A, Giaid A, Sinoff C, Ho AD, Maghazachi AA. Priming effects of granulocyte-macrophage colony-stimulating factor are coupled to cholera toxin-sensitive guanine nucleotide binding protein in human T lymphocytes. Blood 1994; 83: 1299–1309.
   Google Scholar