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Research Article

EXPRESSION AND REGULATION OF THE TRANSCRIPTIONAL REPRESSOR ZNF43 IN EWING SARCOMA CELLS

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Pages 531-540 | Published online: 09 Jul 2009

  • Grier HE. The Ewing family of tumors : Ewing's sarcoma and primitive neuroectodermal tumors. Pediatr Clin North Am. 1997; 44:991-1004.
  • Delattre O, Zucman J, Plougastel B, et al. Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours. Nature. 1992; 359:162-165.
  • Bertolotti A, Melot T, Acker J, Vigneron M, Delattre O, Tora L. EWS, but not EWS-FLI-I, is associated with both TFIID and RNA polymerase, II: interactions between two members of the TET family, EWS and hTAF1168, and subunits of TFIID and RNA polymerase II complexes. MoI Cell Biol. 1998; 18:1489-1497.
  • Petermann R, Mossier BM, Aryee DN, Khazak V, Golemis EA, Kovar H. Oncogenic EWS-Flil interacts with hRBP7, a subunit of human RNA polymerase, II: Oncogene. 1998; 17:603-610.
  • Klemsz MJ, Maki RA, Papayannopoulou T, Moore J, Hromas R. Characterization of the ets oncogene family member, fli-1. J Biol Chem. 1993; 268:5769-5773.
  • Lessnick SL, Braun BS, Denny CT, May WA. Multiple domains mediate transformation by the Ewing's sarcoma EWS/FLI-1 fusion gene. Oncogene. 1995; 10: 423-431.
  • May WA, Gishizky ML, Lessnick SL, et al. Ewing sarcoma 11; 22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation. Proc Natl Acad Sei USA. 1993; 90:5752-5756.
  • Braun BS, Frieden R, Lessnick SL, May WA, Denny CT. Identification of target genes for the Ewing's sarcoma EWS/FLI fusion protein by representational difference analysis. Mol Cell Biol. 1995; 15:4623-4630.
  • Mastrangelo T, Modena P, Tornielli S, et al. A novel zinc finger gene is fused to EWS in small round cell tumor. Oncogene. 2000; 19:3799-3804.
  • Kodama K, Doi O, Higashiyama M, et al. Establishment and characterization of a new Ewing's sarcoma cell line. Cancer Genet Cytogenet. 1991; 57:19-30.
  • Noguera R, Triche TJ, Navarro S, Tsokos M, Llombart-Bosch A. Dynamic model of differentiation in Ewing's sarcoma cells: comparative analysis of morphologic, immunocytochemical, and oncogene expression parameters. Lab Invest. 1992; 66: 143-151.
  • Ralph D, McClelland M, Welsh J. RNA fingerprinting using arbitrarily primed PCR identifies differentially regulated RNAs in mink lung (MvILu) cells growth arrested by transforming growth factor beta 1. Proc Matl Acad Sci USA. 1993; 90:10710-10714.
  • Lovering R, Trowsdale J. A gene encoding 22 highly related zinc fingers is expressed in lymphoid cell lines. Nucleic Adds Res. 1991; 19:2921-2928.
  • Bellefroid EJ, Marine JC, Ried T, et al. Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells. EMBOJ. 1993; 12:1363-1374.
  • Bray P, Lichter P, Thiesen HJ, Ward DC, Dawid IB. Characterization and mapping of human genes encoding zinc finger proteins. PTOC Natl Acad Sci USA. 1991; 88:9563-9567.
  • Karnieli E, Werner H, Rauscher FJ 3rd, Benjamin LE, leRoith D. The IGF-I receptor gene promoter is a molecular target for the Ewing's sarcoma-Wilms' tumor 1 fusion protein. J Biol Chem. 1996; 272:19304-19309.
  • Thompson AD, Braun BS, Arvand A, et al. EAT-2 is a novel SH2 domain containing protein that is up regulated by Ewing's sarcoma EWS/FLI1 fusion gene. Oncogene. 1996; 13: 2649-2658.
  • May WA, Arvand A, Thompson AD, Braun BS, Wright M, Denny CT. EWS/FLI1-induced manic fringe renders NIH 3T3 cells tumorigenic. Nat Genet. 1997; 17:495-497.
  • Ouchida M, Ohno T, Fijimura Y, Rao VN, Reddy ES. Loss of tumorigenicity of Ewing's sarcoma cells expressing antisense RNA to EWS-fusion transcripts. Oncogene. 1995; 11:1049-1054.
  • Kovar H, Aryee DN, Jug G, et al. EWS/FLI-1 antagonists induce growth inhibition of Ewing tumor cells in vitro. Cell Growth Differ. 1996; 7:429-437.
  • Tanaka K, Iwakuma T, Harimaya K, Sato H, IwamotoY. EWS-Flil antisense oligodeoxynucleotide inhibits proliferation of human Ewing's sarcoma and primitive neuroectodermal tumor cells. J Clin Invest. 1997; 99:239-247.
  • Ishiguro H, Kim KT, JohTH, Kim KS. Neuron-specific expression of the human silencer region. J Biol Chem. 1993; 268:17987-17994.
  • Chong JA,Tapia-RamirezJ, Kim S, et al. REST: a mammalian silencer protein that restricts sodium channel gene expression to neurons. Cell. 1995; 80:949-957.
  • Margolin JF, Friedman JR, Meyer WK, Vissing H, Thiesen HJ, Rauscher FJ 3rd. Kruppel-associated boxes are potent transcriptional repression domains. Proc Natl Acad Sci USA. 1994; 91:4509-t513.
  • Pengue G, Calabro V, Bartoli PC, Pagliuca A, Lania L. Repression of transcriptional activity at a distance by the evolutionarily conserved KRAB domain present in a subfamily of zinc finger proteins. Nucleic Acids Res. 1994; 22:2908-2914.
  • Witzgall R, O'Leary E, Leaf A, Onaldi D, Bonventre JV. The Kruppel-associated box-A (KRAB-A) domain of zinc finger proteins mediates transcriptional repression. Proc Natl Acad Sci USA. 1994; 91:4514-4518.

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