- our patients ful? lling the criteria of SS, ANA was
- present only in a minority of the patients (11-35%), 1. Brun JG, Jacobsen H, Kloster R, Cuida M, Johannesen AC,
- RF in only 0-3.8% and SSA or SSB were not detected Hoyeraal HM et al. Use of a sicca symptoms questionnaire
- (Table V). Thus, the relative low prevalence of such for the identi? cation of patients with Sjo¨grens syndrome in a heterogeneous hospital population with various rheumatic
- antibodies in IBD meeting the criteria of SS, may diseases. Clin Exp Rheumatol 1994;12:649-52.
- indicate that the true prevalence of SS is signi? cantly 2. Fox RI, Michelson P. Approaches to the treatment of Sjo¨grens
- lowerthanthemaximum? guresestimated. syndrome. J Rheumatol Suppl 2000;61:15-21.
- Consequently, the prevalence of SS in IBD is prob-3. Manthorpe R. New crieria for diagnosing Sjo¨grens syndrome:
- ably lower than our maximum estimates and SS does a step forward? - or.. Scand J Rheumatol 2001;30 Suppl 115:14-20.
- not seem to occur more frequently in patients with 4. Vitali C, Bombardieri S, Moutsopoulos H et al. A proposal
- IBD than in the general population. for modi? cation of the European classi? cation criteria for
- The reports of SS in patients with IBD are rather Sjo¨grens syndrome. Clin Exp Rheumatol 2000:18; (abstract).
- few (11-14, 26) and larger epidemiological studies 5. Vitali C, Bombardieri S, Jonsson R, Moutsopoulos HM,
- indicating an association between the two disorders Alexander E.L, Carlsons SE et al. Classi? cation Criteria for Sjo¨grens Syndrome: A Revised Version of the European
- are missing. The coexistence of SS and IBD may Criteria proposed by the American-European Consensus
- thus, according to our results, be explained by chance. Group. Ann Rheum Dis 2002; (in press) (abstract).
- A caution should, however, be noted as there was a 6. Jonsson R, Haga HJ, Gordon TP. Current concepts on
- trend towards a higher prevalence of SS in the diagnosis, autoantibodies and therapy in Sjo¨grens syndrome.
- subgroup of patients with highly active intestinal Scand J Rheumatol 2000;29:341-8. 7. Snook JA, de Silva HJ, Jewell DP. The association of auto-
- disease. Investigations of larger groups of such immune disorders with in? ammatory bowel disease. Quart J
- patients are needed to evaluate a possible association Med 1989;72:835-40.
- between SS and subgroups of patients with IBD. 8. Veloso FT, Carvalho J, Magro F. Immune-related systemic
- We cannot fully exclude that SS was present in manifestations of in? ammatory bowel disease. A prospective
- patients not clinically investigated. However, tele-study of 792 patients. J Clin Gastroenterol 1996;23:29-34. 9. Folwaczny C, Noehl N, Endres SP, Heldwein W, Loeschke K,
- phone interviews, questionnaires and a systematic Fricke H. Antinuclear autoantibodies in patients with in? am-
- research of hospital records did not reveal any cases matory bowel disease. High prevalence in ? rst-degree relatives.
- of SS among those who did not volunteer for the Dig Dis Sci 1997;42:1593-7.
- clinical examination. 10. Cox NH, McCrea JD. A case of Sjo¨grens syndrome, sarco-
- Although rheumatic manifestations are common in idosis, previous ulcerative colitis and gastric autoantibodies. Br J Dermatol 1996;134:113 8-40.
- IBD (27) and a few case reports of coexisting SS and
Scandinavian Journal of Rheumatology
Volume 31, 2002 - Issue 3