The Circadian Control of Eclosion

References

• Agiu N., Granger N., Bollenbacher W., Gilbert L. Cellular localization of the insect prothoracicotropic hormone: in vitro assay of a single neurosecretory cell. Proc. Natl Acad. Sci. USA 1979; 76: 5694–5698
   PubMedGoogle Scholar
• Agiu N., Bollenbacher W., Granger N., Gilbert L. Corpus allatum is release site for the insect prothoracicotropic hormone. Nature 1980; 285: 669–670
   Google Scholar
• Akten B., Jauch E., Genova G., Kim E. Y., Edery I., Raabe T., Jackson F. R. A role for CK2 in the Drosophila circadian oscillator. Nature Neurosci. 2003; 6: 251–257
   PubMed Web of Science ®Google Scholar
• Allada R., White N. E., Venus So W., Hall J. C., Rosbash M. A mutant Drosophila homolog of mammalian Clock disrupts circadian rhythms and transcription of period and timeless. Cell 1998; 93: 791–804
   PubMed Web of Science ®Google Scholar
• Ampleford E. J., Steel C. G.H. Circadian control of a daily rhythm in haemolymph ecdysteroid titre in the insect Rhodnius prolixus (Hemiptera). Gen.Comp Endocrinol. 1985; 59: 453–459
   PubMedGoogle Scholar
• Baker J. D., McNabb S. L., Truman J. W. The hormonal coordination of behavior and physiology at adult ecdysis in Drosophila melanogaster. J. Exp. Biol. 1999; 202: 3037–3048
   PubMed Web of Science ®Google Scholar
• Beaver L. M., Gvakharia B. O., Vollintine T. S., Hege D. M., Stanewsky R., Giebultowicz J. M. Loss of circadian clock function decreases reproductive fitness in males of Drosophila melanogaster. PNAS 2002; 99: 2134–2139
   PubMed Web of Science ®Google Scholar
• Blanchardon E., Grima B., Klarsfeld A., Chelot E., Hardin P. E., Preat T., Rouyer F. Defining the role of Drosophila lateral neurons in the control of circadian rhythms in motor activity and eclosion by targeted genetic ablation and PERIOD protein overexpression. Eur. J. Neurosci. 2001; 13: 871–888
   PubMed Web of Science ®Google Scholar
• Brett W. J. Persistent diurnal rhythmicity in Drosophila emergence. Ann. Ent. Soc. Am. 1955; 48: 119–131
   Google Scholar
• Bünning E. Zur Kenntniss der endogonen Tagesrhythmik bei Insekten und Pflanzen. Ber. dt. bot. Ges. 1935; 53: 594–623
   Google Scholar
• Chandrashekaran M. K. Apparent absence of a separate B‐oscillator in phasing the circadian rhythm of eclosion in Drosophila pseudoobscura. Development and Neurobiology of Drosophila, O. Siddiqui, P. Babu, L. M. Hall, J. C. Hall. Plenum Publishing Company. 1980
   Google Scholar
• Cymborowski B., Smietanko A., Delbecque J. P. Circadian modulation of ecdysteroid titre in Galleria mellonella larvae. Comp. Biochem. Physiol. A 1989; 94: 431–438
   PubMedGoogle Scholar
• Cymborowski B., Muszynska‐Pytel M., Porcheron P., Cassier P. Haemolymph ecdysteroid titres controlled by a circadian clock mechanism in the larvae of the wax moth, Galleria mellonella. J. Insect Physiol. 1991; 37: 35–40
   Google Scholar
• Darlington T. K., Wagner‐Smith K., Ceriani M. F., Staknis D., Gekakis N., Steeves T. D.L., Weitz C. J., Takahashi J. S., Kay S. A. Closing the circadian loop: clock‐induced transcription of its own inhibitors per and tim. Science 1998; 280: 1599–1603
   PubMed Web of Science ®Google Scholar
• Dedos F. G., Fugo H. Induction of dauer larvae by application of fenoxycarb early in the fifth instar of the silkworm Bombyx mori. J.Insect Physiol. 1999; 45: 769–775
   PubMedGoogle Scholar
• Dushay M. S., Rosbash M., Hall J. C. The disconnected visual system mutations in Drosophila melanogaster drastically disrupt circadian rhythms. J. Biol. Rhythm. 1989; 4: 1–27
   PubMed Web of Science ®Google Scholar
• Emery I. F., Noveral J. M., Jamison C. F., Siwicki K. K. Rhythms of Drosophila period gene expression in culture. Proc. Natl Acad. Sci. USA 1997; 94: 4092–4096
   PubMed Web of Science ®Google Scholar
• Ewer J., Truman J. W. Increases in cyclic 3′, 5′‐guanosine monophosphate (cGMP) occur at ecdysis in an evolutionarily conserved crustacean cardioactive peptide‐immunoreactive insect neuronal network. J. Comp. Neurol. 1996; 370: 330–341
   PubMedGoogle Scholar
• Ewer J., Gammie S. C., Truman J. W. Control of insect ecdysis by a positive‐feedback endocrine system: roles of eclosion hormone and ecdysis triggering hormone. J. Exp. Biol. 1997; 200: 869–881
   PubMed Web of Science ®Google Scholar
• Ewer J., Truman J. W. Invariant association of ecdysis with increases in 3′, 5′‐guanosine monophosphate (cGMP)‐immunoreactivity in a small network of peptidergic neurons in the hornworm, Manduca sexta. J. Comp. Physiol. 1997; 181: 319–330
   Google Scholar
• Ewer J., Reynolds S. Neuropeptide control of molting insects. Hormones, Brain and Behavior, D. Pfaff, A. Arnold, A. Etgen, S. Fahrbach, R. Rubin. Academic Press. 2002; 1–91
   Google Scholar
• Ewer J., Frisch B., Hamblen‐Coyle M., Rosbash M., Hall J. Expression of the period clock gene within different cell types in the brain of Drosophila adults and mosaic analysis of these cells' influence on circadian behavioral rhythms. J. Neurosci. 1992; 12: 3321
   PubMed Web of Science ®Google Scholar
• Ewer J., De Vente J., Truman J. W. Neuropeptide induction of cyclic GMP increases in the insect CNS: resolution at the level of single identifiable neurons. J. Neurosci. 1994; 14: 7704–7712
   PubMed Web of Science ®Google Scholar
• Frisch B., Hardin P. E., Hamblen‐Coyle M. J., Rosbash M., Hall J. C. A promoterless period gene mediates behavioral rhythmicity and cyclical per expression in a restricted subset of the Drosophila nervous, system. Neuron. 1994; 12: 555–570
   PubMedGoogle Scholar
• Frisch B., Fleissner G., Fleissner G., Brandes C., Hall J. C. Staining in the brain of Pachymorpha sexguttata mediated by an antibody against a Drosophila clock‐gene product: labeling of cells with possible importance for the beetle's circadian rhythms. Cell Tissue Res. 1996; 286: 411–429
   PubMed Web of Science ®Google Scholar
• Fujishita M., Ishizaki H. Circadian clock and prothoracicotropic hormone secretion in relation to the larval–larval ecdysis rhythm of the saturniid Samia cynthia ricini. J. Insect Physiol. 1981; 27: 121–128
   Google Scholar
• Fujishita M., Ishizaki H. Temporal organization of endocrine events in relation to the circadian clock during larval–pupal development in Samia cynthia ricini. J. Insect Physiol. 1982; 28: 77–84
   Google Scholar
• Fujishita M., Ohnishi E., Ishizaki H. The role of ecdysteroids in the determination of gut‐purge timing in saturniid, Samia cynthia ricini. J. Insect Physiol. 1982; 28: 961–967
   Google Scholar
• Gammie S. C., Truman J. W. Neuropeptide hierarchies and the activation of sequential motor behaviors in the hawkmoth, Manduca sexta. J. Neurosci. 1997; 17: 4389–4397
   PubMedGoogle Scholar
• Gammie S. C., Truman J. W. Eclosion hormone provides a link between ecdysis‐triggering hormone and crustacean cardioactive peptide in the neuroendocrine cascade that controls ecdysis behavior. J. Exp. Biol. 1999; 202: 343–352
   PubMedGoogle Scholar
• Giebultowicz J. M., Hege D. M. Circadian clock in Malpighian tubules. Nature 1997; 386: 664
   PubMedGoogle Scholar
• Gilbert L. I., Rybczynski R., Warren J. T. Control and biochemical nature of the ecdysteroidogenic pathway. Annu. Rev. Entomol. 2002; 47: 883–916
   PubMed Web of Science ®Google Scholar
• Glossop N. R., Hardin P. E. Central and peripheral circadian oscillator mechanisms in flies and mammals. J. Cell Sci. 2002; 115: 3369–3377
   PubMed Web of Science ®Google Scholar
• Goto S., Denlinger D. Short‐day and long‐day expression patterns of genes involved in the flesh fly clock mechanism: period, timeless, cycle and cryptochrome. J. Insect Physiol. 2002; 48: 803–816
   PubMed Web of Science ®Google Scholar
• Grima B., Lamouroux A., Chelot E., Papin C., Limbourg‐Bouchon B., Rouyer F. The F‐box protein slimb controls the levels of clock proteins Period and timeless. Nature 2002; 420: 178–182
   PubMed Web of Science ®Google Scholar
• Hardin P. E. Analysis of period mRNA cycling in Drosophila head and body tissues indicates that body oscillators behave differently from head oscillators. Mol. Cell Biol. 1994; 14: 7211–7218
   PubMed Web of Science ®Google Scholar
• Hardin P. E., Hall J. C., Rosbash M. Feedback of the Drosophila period gene on circadian cycling of its messenger RNA levels. Nature 1990; 343: 536–540
   PubMed Web of Science ®Google Scholar
• Helfrich‐Förster C. The period clock gene is expressed in central nervous system neurons which also produce a neuropeptide that reveals the projections of circadian pacemaker cells within the brain of Drosophila melanogaster. Proc. Natl Acad. Sci. USA 1995; 92: 612–616
   PubMed Web of Science ®Google Scholar
• Helfrich‐Förster C. Robust circadian rhythmicity of Drosophila melanogaster requires the presence of lateral neurons: a brain‐behavioral study of disconnected mutants. Comp. Physiol. A 1998; 182: 435–453
   PubMed Web of Science ®Google Scholar
• Helfrich‐Förster C., Tauber M., Park J. H., Muhlig‐Versen M., Schneuwly S., Hofbauer A. Ectopic expression of the neuropeptide pigment‐dispersing factor alters behavioral rhythms in Drosophila melanogaster. J. Neurosci. 2000; 20: 3339–3353
   PubMed Web of Science ®Google Scholar
• Hewes R. S., Truman J. W. Steroid regulation of excitability in identified insect neurosecretory cells. J. Neurosci. 1994; 14: 1812–1819
   PubMedGoogle Scholar
• Hogenesch J. B., Gu Y.‐Z., Jain S., Bradfield C. A. The basic helix‐loop‐helix‐PAS orphan MOP3 forms transcriptionally active complexes with circadian and hypoxia factors. Proc. Natl Acad. Sci. USA 1998; 95: 5474–5479
   PubMed Web of Science ®Google Scholar
• Hunter‐Ensor M., Ousley A., Sehgal A. Regulation of the Drosophila protein timeless suggests a mechanism for resetting the circadian clock by light. Cell 1996; 84: 677–686
   PubMed Web of Science ®Google Scholar
• Kaneko M., Hall J. C. Neuroanatomy of cells expressing clock genes in Drosophila: transgenic manipulation of the period and timeless genes to mark the perikarya of circadian pacemaker neurons and their projections. J. Comp. Neurol. 2000; 422: 66–94
   PubMed Web of Science ®Google Scholar
• Kaneko M., Helfrich‐Förster C., Hall J. C. Spatial and temporal expression of the period and timeless genes in the developing nervous system of Drosophila: newly identified pacemaker candidates and novel features of clock gene product cycling. J. Neurosci. 1997; 17: 6745–6760
   PubMed Web of Science ®Google Scholar
• Kim A.‐J., Cha G.‐H., Kim K., Gilbert L. I., Lee C. C. Purification and characterization of the prothoracicotropic hormone of Drosophila melanogaster. Proc. Natl Acad. Sci. USA 1997; 94: 1130–1135
   PubMedGoogle Scholar
• Kingan T. G., Adams M. E. Ecdysteroids regulate secretory competence in Inka cells. J. Exp. Biol. 2000; 203: 3011–3018
   PubMedGoogle Scholar
• Kingan T. G., Gray W., Zitnan D., Adams M. E. Regulation of ecdysis‐triggering hormone release by eclosion hormone. J. Exp. Biol. 1997; 200: 3245–3256
   PubMed Web of Science ®Google Scholar
• Ko H. W., Jiang J., Edery I. Role for slimb in the degradation of Drosophila period protein phosphorylated by doubletime. Nature 2002; 420: 673–678
   PubMed Web of Science ®Google Scholar
• Koelle M. R., Talbot W. S., Segraves W. A., Bender M. T., Cherbas P., Hogness D. S. The Drosophila EcR gene encodes an ecdysone receptor, a new member of the steroid receptor superfamily. Cell 1991; 67: 59–77
   PubMed Web of Science ®Google Scholar
• Konopka R. J., Benzer S. Clock mutants of Drosophila melanogaster. Proc.Natl Acad. Sci. USA 1971; 68: 2112–2116
   PubMed Web of Science ®Google Scholar
• Krishnan B., Dryer S. E., Hardin P. E. Circadian rhythms in olfactory responses of Drosophila melanogaster. Nature 1999; 400: 375–378
   PubMed Web of Science ®Google Scholar
• Lee C., Bae K., Edery I. The Drosophila CLOCK protein undergoes daily rhythms in abundance, phosphorylation and interactions with the PER‐TIM complex. Neuron. 1998; 21: 857–867
   PubMed Web of Science ®Google Scholar
• Lee C., Bae K., Edery I. PER and TIM inhibit the DNA binding activity of a Drosophila CLOCK‐CYC/dBMAL1. Heterodimer without disrupting formation of the heterodimer: a basis for circadian transcription. Mol. Cell. Biol. 1999; 19: 5316–5325
   PubMed Web of Science ®Google Scholar
• Lin J.‐M., Kilman V., Keegan K., Paddock B., Emery‐Le M., Rosbash M., Allada R. A role for casein kinase 2a in the Drosophila circadian clock. Nature 2002; 420: 816–820
   PubMed Web of Science ®Google Scholar
• Liu X., Lorenz L., Yu Q. N., Hall J. C., Rosbash M. Spatial and temporal expression of the period gene in Drosophila melanogaster. Gene. Dev. 1988; 2: 228–238
   PubMed Web of Science ®Google Scholar
• Markova E., Ueda H., Sakamoto K., Oishi K., Shimada T., Takeda M. Cloning of Cyc (Bmal1) homolog in Bombyx mori: structural analysis and tissue specific distributions. Comp. Biochem. Physiol. B 2003; 134: 535–542
   PubMedGoogle Scholar
• Martinek S., Inonog S., Manoukian A. S., Young M. W. A role for the segment polarity gene shaggy/GSK‐3 in the Drosophila circadian clock. Cell 2001; 105: 769–779
   PubMed Web of Science ®Google Scholar
• McNabb S. L., Baker J. D., Agapite J., Steller H., Riddiford L. M., Truman J. W. Disruption of a behavioral sequence by targeted death of peptidergic neurons in Drosophila. Neuron. 1997; 19: 813–823
   PubMed Web of Science ®Google Scholar
• McNeil G. P., Zhang X., Genova G., Jackson F. R. A molecular rhythm mediating circadian clock output in Drosophila. Neuron. 1998; 20: 297–303
   PubMedGoogle Scholar
• McNeil G. P., Schroeder A. J., Roberts M. A., Jackson F. R. Genetic analysis of functional domains within the Drosophila LARK RNA‐binding protein. Genetics 2001; 159: 229–240
   PubMedGoogle Scholar
• Mesce K. A., Fahrbach S. E. Integration of endocrine signals that regulate insect ecdysis. Front. Neuroendocrin. 2002; 23: 179–199
   PubMedGoogle Scholar
• Mizoguchi A., Ishizaki H. Further evidence for the presence of a circadian clock in prothoracic glands of the surturniid moth Samia cynthia ricini: decapitated larvae can respond to light–dark changes. Dev. Growth Differ. 1984; 26: 607–611
   Google Scholar
• Mizoguchi A., Ohashi Y., Hosoda K., Ishibashi J., Kataoka H. Developmental profile of the changes in the prothoracicotropic hormone titre in haemolymph of the silkworm Bombyx mori: correlation with ecdysteroid secretion. Insect Biochem. Mol. Biol. 2001; 31: 349–358
   PubMed Web of Science ®Google Scholar
• Morton D. B., Truman J. W. Steroid regulation of the peptide‐mediated increase in cGMP in the nervous system of the hawkmoth, Manduca sexta. J. Comp. Physiol. 1985; 157: 423–432
   Google Scholar
• Myers M. P., Wager‐Smith K., Rothenflugh A., Young M. W. Light‐induced degradation of TIMELESS and entrainment of the Drosophila circadian clock. Science 1996; 271: 1736–1740
   PubMed Web of Science ®Google Scholar
• Myers E. M., Yiu J., Sehgal A. Circadian control of eclosion: interaction between a central and peripheral clock in Drosophila melanogaster. Curr. Biol. 2003; 13: 526–533
   PubMed Web of Science ®Google Scholar
• Newby L. M., Jackson F. R. A new biological rhythm mutant of Drosophila melanogaster that identifies a gene with an essential embryonic function. Genetics 1993; 135: 1077–1090
   PubMed Web of Science ®Google Scholar
• Newby L. M., Jackson F. R. Regulation of a specific circadian clock output pathway by lark, a putative RNA‐binding protein with repressor activity. J. Neurobiol. 1996; 31: 117–128
   PubMedGoogle Scholar
• Park J. H., Helfrich‐Förster C., Lee G., Liu L., Rosbash M., Hall J. C. Differential regulation of circadian pacemaker output by separate clock genes in Drosophila. Proc. Natl. Acad. Sci. USA 2000; 97: 3608–3613
   PubMed Web of Science ®Google Scholar
• Park J., Schroeder A. J., Helfrich‐Forster C., Jackson F. R., Ewer J. Targeted ablation of CCAP neuropeptide‐containing neurons of Drosophila causes specific defects in execution and circadian timing of ecdysis behavior. Development 2003; 130: 2645–2656
   PubMedGoogle Scholar
• Pelc D., Steel C. G.H. Rhythmic steroidogenesis by the prothoracic glands of the insect Rhodnius prolixus in the absence of rhythmic neuropeptide input: implications for the role of prothoracicotropic hormone. Gen. Comp. Endocrinol. 1997; 108: 358–365
   PubMedGoogle Scholar
• Piccin A., Couchman M., Clayton J. D., Chalmers D., Costa R., Kyriacou C. P. The clock gene period of the housefly, Musca domestica, rescues behavioral rhythmicity in Drosophila melanogaster: evidence for intermolecular coevolution?. Genetics 2000; 154: 747–758
   PubMedGoogle Scholar
• Pittendrigh C. S. On temperature independence in the clock controlling emergence time in Drosophila. Proc. Natl. Acad. Sci. USA 1954; 40: 1018–1029
   PubMed Web of Science ®Google Scholar
• Pittendrigh C. S. Perspectives in the study of biological clocks. Perspectives in Marine Biology, A. A. Buzzati‐Traverso. University of California Press. 1958; 239–268
   Google Scholar
• Pittendrigh C. S. On the mechanism of entrainment of circadian rhythm by light cycles. Circadian Clocks, J. Aschoff. North‐Holland, Amsterdam 1965; 277–297
   Google Scholar
• Pittendrigh C. S. Circadian systems I. The driving oscillation and its assay in Drosophila pseudoobscura. Proc. Natl. Acad. Sci. USA 1967; 58: 1762–1767
   PubMed Web of Science ®Google Scholar
• Pittendrigh C. S., Bruce V. G. An oscillator model for biological clocks. Rhythmic and Synthetic Processes in Growth, D. Rudnick. Princeton University Press, Princeton, NJ 1957; 75–109
   Google Scholar
• Pittendrigh C. S., Bruce V. G. Daily rhythms as coupled oscillator systems and their relation to thermoperiodism and photoperiodism. Photoperiodism and Related Phenomena in Plants and Animals, R. B. Withrow. American Association for the Advancement of Science, Washington 1959; 475–505
   Google Scholar
• Pittendrigh C. S., Skopik S. D. Circadian systems, V. The driving oscillation and the temporal sequence of development. Proc. Natl. Acad. Sci. 1970; 65: 500–507
   PubMed Web of Science ®Google Scholar
• Plautz J. D., Kaneko M., Hall J. C., Kay S. A. Independent photoreceptive circadian clocks throughout Drosophila. Science 1997; 278: 1632–1635
   PubMed Web of Science ®Google Scholar
• Price J. L., Blau J., Rothenflugh A., Abodeely M., Kloss B., Young M. W. double‐time is a novel Drosophila clock gene that regulates PERIOD protein accumulation. Cell 1998; 94: 83–95
   PubMed Web of Science ®Google Scholar
• Qiu J., Hardin P. E. Developmental state and the circadian clock interact to influence the timing of eclosion in Drosophila melanogaster. J. Biol. Rhythm. 1996; 11: 75–86
   PubMed Web of Science ®Google Scholar
• Renn S. C.P., Park J. H., Rosbash M., Hall J. C., Taghert P. H. A pdf neuropeptide gene mutation and ablation of PDF neurons each cause severe abnormalities of behavioral circadian rhythms in Drosophila. Cell 1999; 99: 791–802
   PubMed Web of Science ®Google Scholar
• Reppert S. M., Tsai T., Roca A. L., Sauman I. Cloning of a structural and functional homolog of the circadian clock gene period from the giant silkmoth Antheraea pernyi. Neuron. 1994; 13: 1167–1176
   PubMed Web of Science ®Google Scholar
• Richter K. Daily changes in neuroendocrine control of moulting hormone secretion in the prothoracic gland of the cockroach Periplanta americana (L.). J. Insect Physiol. 2001; 47: 333–338
   PubMedGoogle Scholar
• Rutila J. E., Suri V., Le M., So W. V., Rosbash M., Hall J. C. CYCLE is a second bHLH‐PAS clock protein essential for circadian rhythmicity and transcription of Drosophila period and timeless. Cell 1998; 93: 805–814
   PubMed Web of Science ®Google Scholar
• Saez L., Young M. W. In situ localization of the per clock protein during development of Drosophila melanogaster. Mol. Cell. Biol. 1988; 8: 5378–5385
   PubMed Web of Science ®Google Scholar
• Sakurai S. Temporal organization of endocrine events underlying larval–larval ecdysis in the silkworm, Bombyx mori. J. Insect Physiol. 1983; 29: 919–932
   Web of Science ®Google Scholar
• Sakurai S. Temporal organization of endocrine events underlying larval– pupal metamorphosis in the silkworm, Bombyx mori. J. Insect Physiol. 1984; 30: 657–664
   Web of Science ®Google Scholar
• Sakurai S., Kaya M., Satake S. Haemolymph ecdysteroid titre and ecdysteroid‐dependent developmental events in the larval–pupal stadium of the silkworm, Bombyx mori: role of low ecdysteroid titre in larval–pupal metamorphosis and a reappraisal of the head critical period. J. Insect Physiol. 1998; 44: 867–881
   PubMedGoogle Scholar
• Sauman I., Reppert S. M. Circadian clock neurons in the silkmoth Antheraea pernyi: novel mechanisms of period protein regulation. Neuron. 1996; 17: 889–900
   PubMed Web of Science ®Google Scholar
• Saunders D. S., Steel C. G.H., Vafopoulo X., Lewis R. D. Insect Clocks. Elsevier Science B.V., Amsterdam 2002
   Google Scholar
• Schwartz L. M., Truman J. W. Hormonal control of rates of metamorphic development in the tobacco hornworm Manduca sexta. Devel. Biol. 1983; 99: 103–114
   PubMed Web of Science ®Google Scholar
• Sehgal A., Price J. L., Man B., Young M. W. Loss of circadian behavioral rhythms and per RNA oscillations in the Drosophila mutant timeless. Science 1994; 263: 1603–1606
   PubMed Web of Science ®Google Scholar
• Sehgal A., Rothenfluh‐Hilfiker A., Hunter‐Ensor M., Chen Y., Myers M. P., Young M. W. Rhythmic expression of timeless: a basis for promoting circadian cycles in period gene autoregulation. Science 1995; 270: 808–810
   PubMedGoogle Scholar
• Shibanaka Y., Hayashi H., Okada N., Fujita N. The crucial role of cGMP in the eclosion hormone mediated signal transduction in the silkworm metamorphoses. Biochem. Biophys. Res. Commun. 1991; 180: 881–886
   PubMedGoogle Scholar
• Siegmund T., Korge G. Innervation of the ring gland of Drosophila melanogaster. J. Comp. Neurol. 2001; 431: 481–491
   PubMedGoogle Scholar
• Siwicki K. K., Eastman C., Petersen G., Rosbash M., Hall J. C. Antibodies to the period gene product of Drosophila reveal diverse tissue distribution and rhythmic changes in the visual system. Neuron. 1988; 1: 141–150
   PubMed Web of Science ®Google Scholar
• Stanewsky R. Clock mechanisms in Drosophila. Cell Tissue Res. 2002; 309: 11–26
   PubMed Web of Science ®Google Scholar
• Steel C. G.H., Ampleford E. J. Circadian control of haemolymph ecdysteroid titers and the ecdysis rhythm in Rhodnius prolixus. Photoperiodic Regulation of Insect and Mollusca Hormones, R. Porter, G. M. Collins. Pitman, LondonUK 1984; 150–162
   Google Scholar
• Talbot W. S., Swywryd E. A., Hogness D. S. Drosophila tissues with different metamorphic responses to ecdysone express different ecdysone receptor isoforms. Cell 1993; 73: 1323–1337
   PubMed Web of Science ®Google Scholar
• Tanaka K., Watari Y. Adult eclosion timing of the onion fly, Delia antiqua, in response to daily cycles of temperature at different soil depths. Naturwissenschaften 2003; 90: 76–79
   PubMed Web of Science ®Google Scholar
• Thomas H. E., Stunnenberg H. G., Stewart A. F. Heterodimerization of the Drosophila ecdysone receptor with retinoid X receptor and ultraspiracle. Nature 1993; 362: 471–475
   PubMed Web of Science ®Google Scholar
• Thummel C. S. Edysone‐regulated puff genes 2000. Insect Biochem. Mol. Biol. 2002; 32: 113–120
   PubMed Web of Science ®Google Scholar
• Truman J. W. Physiology of insect rhythms. I. Circadian organization of the endocrine events underlying the moulting cycle of larval tobacco hornworms. J. Exp. Biol. 1972a; 57: 805–820
   Web of Science ®Google Scholar
• Truman J. W. Physiology of insect rhythms. II. The silkworm brain as the location of the biological clock controlling eclosion. J. Comp. Physiol. 1972b; 81: 99–114
   Web of Science ®Google Scholar
• Truman J. W., Riddiford L. W. Neuroendocrine control of ecdysis in silk‐moths. Science, Wash. 1970; 167: 1624–1626
   PubMed Web of Science ®Google Scholar
• Truman J. W., Riddiford L. M. Endocrine insights into the evolution of metamorphosis in insects. Annu. Rev. Entomol. 2002; 47: 467–500
   PubMed Web of Science ®Google Scholar
• Truman J. W., Rountree D. B., Reiss S. E., Schwartz L. M. Ecdysteroids regulate the release and action of eclosion hormone in the tobacco hornworm, Manduca sexta (L.). J. Insect Physiol. 1983; 29: 895–900
   Web of Science ®Google Scholar
• Vafopoulou X., Steel C. G.H. Developmental and diurnal changes in ecdysteroid biosynthesis by prothoracic glands of Rhodnius prolixus (Hemiptera) in vitro during the last larval instar. Gen. Comp. Endocrinol. 1989; 74: 484–493
   PubMedGoogle Scholar
• Vafopoulou X., Steel C. G.H. The insect neuropeptide prothoracicotropic hormone is released with a daily rhythm: re‐evaluation of its role in development. Proc. Natl. Acad. Sci. USA 1996a; 93: 3368–3372
   PubMedGoogle Scholar
• Vafopoulou X., Steel C. G.H. Circadian regulation of a daily rhythm of release of prothoracicotropic hormone from the brain‐retrocerebral complex of Rhodnius prolixus (Hemiptera) during larval–adult development. Gen. Comp. Endocrinol. 1996b; 102: 123–129
   PubMedGoogle Scholar
• Vafopoulou X., Steel C. G.H. A photosensitive circadian oscillator in an insect endocrine gland: photic induction of rhythmic steroidogenesis in vitro. J. Comp. Physiol. 1998; 182: 343–349
   Google Scholar
• Vosshall L. B., Young M. W. Circadian rhythms in Drosophila can be driven by period expression in a restricted group of central brain cells. Neuron. 1995; 15: 345–360
   PubMedGoogle Scholar
• Warman G. R., Newcomb R. D., Lewis R. D., Evans C. W. Analysis of the circadian clock gene period in the sheep blow fly Lucilia cuprina. Genetical Research 2000; 75: 257–267
   PubMed Web of Science ®Google Scholar
• Wise S., Davis N. T., Tyndale E., Noveral J., Folwell M. G., Bedian V., Emery I. F., Siwicki K. K. Neuroanatomical studies of period gene expression in the hawkmoth, Manduca sexta. J.Comp. Neurol. 2002; 447: 366–380
   PubMedGoogle Scholar
• Yang Z., Sehgal A. Role of molecular oscillations in the Drosophila circadian clock. Neuron. 2001; 29: 453–467
   PubMed Web of Science ®Google Scholar
• Yao T. P., Forman B. M., Segraves W. A., Oro A. E., McKeown M., Cherbas P., Evans R. M. Drosophila ultraspiracle modulates ecdysone receptor function via heterodimer formation. Cell 1992; 71: 63–72
   PubMed Web of Science ®Google Scholar
• Yao T. P., Forman B. M., Jiang Z. Y., Cherbas L., Chen J. D., McKeown M., Cherbas P., Evans R. M. Functional ecdysone receptor is the product of EcR and ultraspiracle genes. Nature 1993; 366: 476–479
   PubMed Web of Science ®Google Scholar
• Zavodska R., Sauman I., Sehnal F. Distribution of PER protein, pigment‐dispersing hormone, prothoracicotropic hormone, and eclosion hormone in the cephalic nervous system of insects. J. Biol. Rhythm. 2003; 18: 106–122
   PubMed Web of Science ®Google Scholar
• Zhang X., McNeil G. P., Hilderbrand‐Chae M. J., Franklin T. M., Schroeder A. J., Jackson F. R. Circadian regulation of the lark RNA‐binding protein within identifiable neurosecretory cells. J. Neurobiol. 2000; 45: 14–29
   PubMedGoogle Scholar
• Zimmerman W. F., Ives D. Some photophysiological aspects of circadian rhythmicity in Drosophila. Biochronometry, M. Menaker. National Academy of Sciences, Washington, 381–391
   Google Scholar
• Zimmerman W. F., Pittendrigh C. S., Pavlidis T. Temperature compensation of the circadian oscillation in Drosophila pseudoobscura and its entrainment by temperature cycles. J. Insect Physiol. 1968; 14: 669–684
   PubMed Web of Science ®Google Scholar
• Zitnan D., Adams M. E. Excitatory and inhibitory roles of central ganglia in initiation of the insect ecdysis behavioural sequence. J. Exp. Biol. 2000; 203: 1329–1340
   PubMed Web of Science ®Google Scholar
• Zitnan D., Sehnal F., Bryant P. J. Neurons producing specific neuropeptides in the central nervous system of normal on pupariation‐delayed Drosophila. Dev. Biol. 1993; 156: 117–135
   PubMed Web of Science ®Google Scholar
• Zitnan D., Kingan T. G., Hermesman J. L., Adams M. E. Identification of ecdysis‐triggering hormone from epitracheal endocrine system. Science 1996; 271: 88–91
   PubMed Web of Science ®Google Scholar
• Zitnan D., Ross L. S., Zitnanova I., Hermesman J. L., Gill S. S., Adams M. E. Steroid induction of a peptide hormone gene lead to orchestration of a defined behavioral sequence. Neuron. 1999; 23: 523–535
   PubMed Web of Science ®Google Scholar