L-NAME, A NITRIC OXIDE SYNTHASE INHIBITOR, AS A POTENTIAL COUNTERMEASURE TO POST-SUSPENSION HYPOTENSION IN RATS

REFERENCES

• Bungo M. W., Charles J. B., Johnson P. C. Cardiovascular deconditioning during space flight and the use of saline as a counter-measure to orthostatic intolerance. Aviat. Space Environ. Med. 1985; 56: 985–990
   PubMed Web of Science ®Google Scholar
• Lacolley P. J., Pannier B. M., Cuche J. L., Hermida J. S., Laurent S., Maisonblanche P., Duchier J. L., Levy B. I., Safar M. E. Microgravity and orthostatic intolerance: carotid hemodynamics and peripheral responses. Amer. J. Physiol. 1993; 264: H588–H594
   PubMed Web of Science ®Google Scholar
• Quyyumi A. A., Dakak N., Andrews N. P, Husain S., Arora S., Gilligan D. M., Panza J. A., Cannon R. O., III. Nitric oxide activity in the human coronary circulation. J. Clin. Invest. 1995; 95: 1747–1755
   PubMed Web of Science ®Google Scholar
• Baylis C., Harton P., Engels K. Endothelial-derived relaxing factor controls renal haemodynamics in the normal rat kidney. J. Amer. Soc. Nephrol. 1990; 1: 875–881
   PubMed Web of Science ®Google Scholar
• Loeb A. L., Longnecker D. E. Inhibition of endothelium-derived relaxing factor-dependent circulatory control in intact rats. Amer. J. Physiol. 1992; 262: H1494–H1500
   PubMed Web of Science ®Google Scholar
• Mattson D. L., Higgins D. J. Influence of dietary sodium intake on renal medullary nitric oxide synthase. Hypertension 1996; 27: 688–692
   PubMed Web of Science ®Google Scholar
• Nelson M. T., Quayle J. M. Physiological roles and properties of potassium channels in arterial smooth muscle. Amer. J. Physiol. 1995; 268: C799–C822
   PubMed Web of Science ®Google Scholar
• Lipp P., Niggli E. A hierarchical concept of cellular and subcellular Ca2+-signalling. Progr. Biophys. Mol. Biol. 1996; 65: 265–296
   PubMed Web of Science ®Google Scholar
• Musacchia X. J., Steffen J. M., Dombrowski J. Rat cardiovascular responses to whole body suspension: head-down and non head-down tilt. J. Appl. Physiol. 1992; 73: 1504–1509
   PubMed Web of Science ®Google Scholar
• Head G. A., McCarty R. Vagal and sympathetic components of the heart rate range and gain of the baroreceptor-heart rate reflex in conscious rats. J. Auton. Nerv. Syst. 1987; 21: 203–213
   PubMedGoogle Scholar
• Murphy C. A., McCarty R. Baroreflex control of heart rate in Dahl hypertensive (SS/Jr) and normotensive (SR/Jr) rats. J. Hypertension 1995; 13: 1145–1151
   PubMed Web of Science ®Google Scholar
• Bayorh M. A., Socci R. R., Wang M., Thierry-Palmer M., Emmett N. Influence of simulated microgravity on cardiovascular and hemodynamic parameters in Dahl salt-sensitive rats. J. Gravit. Physiol. 1999; 6: 63–70
   PubMedGoogle Scholar
• Socci R. R., Wang M., Thierry-Palmer M., Emmett N., Bayorh M. A. Cardiovascular responses to simulated microgravity in Sprague-Dawley rats. Clin. Exper. Hypertension 2000; 22: 155–164
   PubMed Web of Science ®Google Scholar
• Rees D. D., Palmer R. M.J., Moncada S. Role of endothelium-derived nitric oxide in the regulation of blood pressure. Proc. Natl. Acad. Sci., USA 1989; 86: 3375–3378
   PubMed Web of Science ®Google Scholar
• Vanhoutte P. M., Rubanyi G. M., Miller V. M., Houston D. S. Modulation of vascular smooth muscle contraction by the endothelium. Annu. Rev. Physiol. 1986; 48: 307–320
   PubMed Web of Science ®Google Scholar
• Gryglewski R. J., Botting R. M., Vane J. R. Mediators produced by the endothelial cell. Hypertension 1988; 12: 530–548
   PubMed Web of Science ®Google Scholar
• Bayorh M. A., Socci R. R., Watts S., Wang M., Eatman D., Thierry-Palmer M. L-NAME, a nitric oxide synthase inhibitor, as a potential countermeasure to post-suspension hypotension. FASEB J. 2000; 14: A1377, (Abstr.)
   Web of Science ®Google Scholar
• Eckberg D. L., Fritsch J. M. Human autonomic response to actual and simulated weightlessness. J. Clin. Pharmacol. 1991; 31: 951–955
   PubMed Web of Science ®Google Scholar
• Bryant C. E., Allock G. H., Warner T. D. Comparison of effects of chronic and acute administration of NG-nitro-L-arginine methyl ester to the rat on inhibition of nitric oxide-mediated responses. Br. J. Pharmacol. 1995; 114: 1673–1679
   PubMed Web of Science ®Google Scholar
• Sangha D. S., Vaziri N. D., Ding Y., Purdy R. E. Vascular hyporesponsiveness in simulated microgravity: role of nitric oxide-dependent mechanisms. J. Appl. Physiol. 2000; 88: 507–517
   PubMed Web of Science ®Google Scholar
• Bayorh M. A., Socci R. R., Wang M., Emmett N., Thierry-Palmer M. Effect of simulated microgravity on baroreflex activity and metabolic parameters in the Dahl salt-sensitive rats. Gravit. Space biol. Bull. 1998; 12: 81, (Abstr.)
   Google Scholar
• Bayorh M. A., Socci R. R., Wang M., Emmett N., Thierry-Palmer M. Combined effect of salt-loading and simulated microgravity on baroreflex responsiveness in rats. J. Gravit. Physiol., (in press)
   Google Scholar
• Shellock F. G.H., Swan J. J.C., Rubin S. A. Early central venous pressure changes in the rat during two different levels of head-down suspension. Aviat. Space Environ. Med. 1985; 56: 791–795
   PubMed Web of Science ®Google Scholar
• Martel E., Lacolley P., Champeroux P., Brisac A. M., Laurent S., Cuche J. L., Safar M. E. Early disturbance of baroreflex control of heart rate after tail-suspension in conscious rats. Amer. J. Physiol. 1994; 267: H2407–H2412
   PubMed Web of Science ®Google Scholar
• Deavers D. R., Musacchia X. J., Meininger G. A. Model for antiorthostatic hypokinesia: head-down tilt effects on water and salt excretion. J. Appl. Physiol. 1980; 49: 576–582
   PubMed Web of Science ®Google Scholar
• Morimoto T., Sugimoto E., Nose H., Okuno T., Natsuyama T., Morita M. Continuous determination of blood volume and blood sodium concentration on conscious rats: A potential tool for the analysis of water balance during weightlessness. Physiologist 1987; 30: S90–S99
   PubMedGoogle Scholar
• Scrogin K. E., Hatton D. C., Chi Y., Luft F. C. Chronic nitric oxide inhibition with L-NAME: effects on autonomic control of the cardiovascular system. Amer. J. Physiol. 1998; 274: R367–R374
   PubMed Web of Science ®Google Scholar
• Souza H. C.D, Ballejo G., Salgado M. C.O., Dias da Silva V. J., Salgado H. C. Cardiac sympathetic overactivity and decreased baroreflex sensitivity in L-NAME hypertensive rats. Amer. J. Physiol. 2001; 280: H844–H850
   Web of Science ®Google Scholar