393
Views
22
CrossRef citations to date
0
Altmetric
Research Article

Effect of Microcrystalline Cellulose Grade and Process Variables on Pellets Prepared by Extrusion–Spheronization

, , , &
Pages 451-456 | Published online: 16 May 2002

REFERENCES

  • Harrison P.J., Newton J.M., Rowe R.C. Application of Capillary Rheometry to the Extrusion of Wet Powder Masses. Int. J. Pharm. 1987; 35: 235–242
  • Parker M.D., Rowe R.C., Upjohn N.G. Mixer Torque Rheometry: A Method for Quantifying the Consistency of Wet Granulations. Pharm. Tech. Int. 1990; 2: 50–62
  • Rowe R.C., Parker M.D. Mixer Torque Rheometry. An Update. Pharm. Tech. Eur. 1994; 6: 24–27
  • Delalonde M., Baylac G., Bataille B., Jacob M., Puech A. The Rheology of Wet Powders: A Measuring Instrument, the Compresso-Rheometer. Int. J. Pharm. 1996; 130: 147–151
  • Hancock B.C., York P., Rowe R.C. Characterization of Wet Masses Using a Mixer Torque Rheometer: 2. Mixing Kinetics. Int. J. Pharm. 1992; 83: 147–153
  • Parker M.D., York P., Rowe R.C. Binder–Substrate Interactions in Wet Granulation. 1: The Effect of Binder Characteristics. Int. J. Pharm. 1990; 64: 207–216
  • Parker M.D., York P., Rowe R.C. Binder–Substrate Interactions in Wet Granulation. 2: The Effect of Binder Molecular Weight. Int. J. Pharm. 1991; 72: 243–249
  • Parker M.D., York P., Rowe R.C. Binder–Substrate Interactions in Wet Granulation. 3: The Effect of Excipient Source Variation. Int. J. Pharm. 1992; 80: 179–190
  • Landín M., York P., Cliff M.J., Rowe R.C., Wigmore A.J. Scale-up of a Pharmaceutical Granulation in Fixed Bowl Mixer-Granulators. Int. J. Pharm. 1996; 133: 127–131
  • Exner H.E., Link E. Image Analysis for Characterization of Size and Shape Distribution of Lead Powders Powder Metall. Int. 1977; 9: 131–133
  • Micromeritics Instruction Manual Pores Size 9305. Micromeritics, Norcross, GA 1984
  • Thomson F.M. Storage of Particulate Solids. Handbook of Powder Science and Technology, M.E. Fayed, L. Otten. Van Nostrand Reinhold, New York 1984; 365–463
  • Statgraphics, Version 7.0. Manugistics Inc., Statistical Graphics Corp., Los Angeles 1993
  • Landín M., Rowe R.C., York P. Characterization of Wet Powder Masses with a Mixer Torque Rheometer. 3. Nonlinear Effects of Shaft Speed and Sample Weight. J. Pharm. Sci. 1995; 84: 557–559
  • Rowe R.C., Sadeghnejad G.R. The Rheology of Microcrystalline Cellulose Powder/Water Mixes—Measurement Using a Mixer Torque Rheometer. Int. J. Pharm. 1987; 38: 227–229
  • Law M.F.L., Deasy P.B. Use of Hydrophilic Polymers with Microcrystalline Cellulose to Improve Extrusion–Spheronization. Eur. J. Pharm. Biopharm. 1998; 45: 57–65
  • Thoma K., Ziegler I. Investigations on the Influ- ence of the Type of Extruder for Pelletization by Extrusion–Spheronization. II. Sphere Charac- teristics. Drug Dev. Ind. Pharm. 1998; 24: 413–422
  • Umprayn K., Chitopras P., Amarekajorn S. Influence of Process Variables on Physical Properties of the Pellets Using Extruder and Spheronizer. Drug Dev. Ind. Pharm. 1999; 25: 45–61
  • Vervaet C., Baert L., Remon J.P. Extrusion–Spheronization. A Literature Review. Int. J. Pharm. 1995; 116: 131–146

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.