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Research Article

PROTECTIVE EFFECTS OF DEBO ON ZINC-INDUCED APOPTOSIS OF C6 GLIAL CELLS VIA MODULATION OF INTRACELLULAR ANTIOXIDANT, REDUCED GLUTATHIONE

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Pages 383-396 | Published online: 31 Jul 2001

REFERENCES

  • Kim Y. C., Kim S. K., Markelonis G. J., Oh T. H. Ginsenosides Rb1 and Rg3 protect cultures rat cortical cells from glutamate-induced neurodegeneration. J Neurosci Res. 1998; 15;53(4)426–432
  • Xiao Qiu, Rui Wang, Yi Fan, Xi Can. Protective effects of huperzine A on beta-amyloid (25–35) induced oxidative injury in rat pheochrocytoma cells. Neuroscience Letters 2000; 286: 155–158
  • Adams J. D., Klaidman L. K. Alzheimer's disease and Parkinson's disease: brain levels of glutathione, glutathione disulfide and vitamin E. Mol. Chem. Neuropathol. 1991; 14: 213–225
  • Chan P. H. Oxygen radicals in focal cerebral ischemia. Brain Pathol. 1994; 4: 59–64
  • Christen Y. Oxidative stress and Alzheimer disease. Am J Clin Nutr. 2000; 71(2)621–629
  • Lee J. Y., Cole T. B., Palmiter R. D., Koh J. Y. Accumulation of zinc in degenerating hippocampal neurons of ZnT3-null mice after seizures: evidence against synaptic vesicle origin. J Neurosci. 2000; 1;20(11)RC79
  • Canzoniero L. M., Turetsky D. M., Choi D. W. Measurement of intracellular free zinc concentrations accompanying zinc-induced neuronal death. J Neurochem. 1999; 1;19(19)RC31
  • Shivakumar B. R., Kolluri S. V., Ravindranath V. Glutathione and protein thiol homeostasis in brain during reperfusion after cerebral ischemia. J Pharmacol Exp Ther. 1995; 274: 1167–1173
  • Cookson M. R., Shaw P. J. Oxidative stress and motor neuron disease. Brain Pathol. 1999; 9(1)165–186
  • Hall E. D., McCall J. M., Means E. D. Therapeutic potential of the lazaroids (21-aminosteroids) in acute central nervous system trauma, ischemia and subarachnoid hemorrhage. Ads Pharmacol. 1994; 28: 221–268
  • Juurlink B. H.J., Sweeney M. I. Mechanisms that result in damage during and following cerebral ischemia. Neurosci Behav Rev. 1997; 21: 121–128
  • Koh J., Suh S., Gwag B., He Y., Hsu C., Choi D. The role of zinc in selective neuronal death after transient global cerebral ischemia. Science 1996; 272: 1013–1016
  • Siesjo B. K., Zhao Q., Pahlmark K., Katsura K., Folbergrova J. Glutamate, calcium and free radical as mediators of ischemic brain damage. Ann. Thorac. Surg. 1995; 59: 1316–1320
  • Ye J., Ding M., Leonard S. S., Robinson V. A., Millecchia L., Zhang X., Castranova V., Vallyathan V., Shi X. Vanadate induces apoptosis in epidermal JB6 P+ cells via hydrogen peroxide-mediated reactions. Mol Cell Biochem. 1999 Dec; 202(1–2)9–17
  • Colowick S. P., Kaplan N. O. Determination of the production of superoxide radicals and hydrogen peroxide in mitochondria. Method in Enzymology 1990; 429–435
  • Tieze F. Enzymic method of quantitive determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal. Biochem. 1969; 27: 502–522
  • Dignam J. D., Lebovitz R. M., Roeder R. G. Nucleic Acids Res. 1983; 11: 1475–1489
  • Staniek K., Nohl H. H2O2 detection from intact mitochondria as a measure for one-electron reduction of dioxygen requires a non-invasive assay system. Biochim Biophys Acta. 1999 Oct; 6;1413(2)70–80
  • Gots M. E., Freyberger A., Riederer P. Oxidative stress: a role of in the pathogenesis of Parkinson's disease. J Neural Transm Suppl. 1990; 29: 241–249
  • Benzi G., Moretti A. Age-related effect induced by oxidative stress on the cerebral glutathione system. Neurochem. Res. 1989; 14: 473–481
  • Jaswinder S. B., Christopher A. S. Neurodegenerative disorders in humans: the role of glutathione in oxidative stress-mediated neuronal death. Brain Research 1997; 25: 335–338
  • Kato S., Negishi K., Mawatari K., Kuo C. H. A mechanism for glutamate toxicity in the C6 glioma cells involving inhibition of cysteine uptake leading to glutathione depletion. Neuroscience 1992; 48: 903–914
  • Fraker Pamela J., Telford William G. A reappraisal of the role of zinc in life and death decisions of cells. P.S.E.B.M. 1997; 215: 229–236
  • Barbieri D., Troiano L., Grassilli E., Agnrsini C., Cristofalo E., Monit D., Capri M. Inhibition of apoptosis by zinc: A reappraisal. Biochem Biophys Res Commun. 1992; 187: 1256–1261
  • Fraker P., Telford W. Regulation of apoptotic events by zinc. nutrition and gene expression. CRC, , FL 1996; 189–208
  • Cuajungco Math P., Lees Gordon J. Zinc metabolism in the brain: Relevance to human neurodegenerative disorders. Neurobiol Disease 1997; 4: 137–169
  • Noh K. M., Kim Y. H., Koh J. Y. Mediation by membrane protein kinase C of zinc-induced oxidative neuronal injury in mouse cortical cultures. J Neurochem. 1999; 72(4)1609–1616
  • Park J. A., Koh J. Y. Induction of an immediate early gene egr-1 by zinc through extracellular signal-regulated kinase activation in cortical culture: its role in zinc-induced neuronal death. J Neurochem. 1999; 73(2)450–456
  • Danfour M., Schorah C. J., Evans S. W. Changes in sensitivity of human myeloid cell line (U937) to metal toxicity after glutathione depletion. Immunopharmacol & Immunotoxicol 1999; 21(2)277–293
  • Baeuerle P. A., Henkel T. Function and activation of NF-kappa B in the immune system. Annu Rev Immunol. 1994; 12: 141–179
  • Baeuerle P. A., Baltimore D. NF-kappa B: Ten years after. Cell. 1996; 87: 13–20
  • O'Neill L. A., Kaltschmidt C. NF-kappa B: A crucial transcription factor for glial and neuronal cell function. Trends Neurosci. 1997; 20: 252–258
  • Kaltschmidt C., Kaltschmidt B., Henkel T., Stockinggen H., Baeuerle P. A. Selective recognition of the activated form of transcription factor NF-κB by a monoclonal antibody. Biol Chem Hoppe Seyler 1995; 376: 9–16
  • Meyer M., Schreck R., Baeuerle P. A. H2O2 and antioxidants have opposite effects on activation of NF-κB and AP-1 in intact cells: AP-1 as secondary antioxidant responsive factor. EMBO J. 1993; 12: 2005–2015
  • Schreck H., Klein M., Erdbrugger W., Droge W., Schulze Osthoff K. Distinct effects of thioredoxin and antioxidants on the activation of transcription factors NF-κB and AP-1. Proc Natl Acad Sci. USA. 1994; 91: 1672–1676

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