Subchronic Exposure to Ellagic Acid Impairs Cytotoxic T‐Cell Function and Suppresses Humoral Immunity in Mice

References

• Daniel E. M., Ratnayake S., Kinstle T., Stoner G. D. The effects of pH and rat intestinal contents on the liberation of ellagic acid from purified and crude ellagitannins. J. Natr. Prod. 1991; 54(4)946–952
   PubMedGoogle Scholar
• Fruits and Tree Nuts: Situation and Outlook Yearbook. U.S. Department of Agriculture, Hyattsville, MD 1988, USDA Economic Research Service.
   Google Scholar
• Shugart L., Kao J. Effect of ellagic and caffeic acids on covalent binding of benzo[a]pyrene to epidermal DNA of mouse skin in organ culture. Int. J. Biochem. 1984; 16(5)571–573
   PubMedGoogle Scholar
• Barch D. H., Rundhaugen L. M., Stoner G. D., Pillay N. S., Rosche W. A. Structure–function relationships of the dietary anticarcinogen ellagic acid. Carcinogen 1996; 17(2)265–269
   PubMed Web of Science ®Google Scholar
• Castonguay A., Boukharta M., Teel R. Biodistribution of, antimutagenic efficacies in Salmonella typhimurium of, and inhibition of P450 activities by ellagic acid and one analogue. Chem. Res. Toxicol. 1998; 11: 1258–1264
   PubMed Web of Science ®Google Scholar
• Teel R. W. Ellagic acid binding to DNA as a possible mechanism for its antimutagenic and anticarcinogenic action. Cancer Lett. 1986; 30: 329–336
   PubMed Web of Science ®Google Scholar
• Mukhtar H., Mukul D., Bickers D. R. Inhibition of 3‐methylcholanthrene‐induced skin tumorigenicity in BALB/c mice by chronic oral feeding of trace amounts of ellagic acid in drinking water. Cancer Res. 1986; 46: 2262–2265
   PubMed Web of Science ®Google Scholar
• Ahn D., Putt D., Kresty L., Stoner G. D., Fromm D., Hollenberg P. F. The effects of dietary ellagic acid on rat hepatic and esophageal mucosal cytochromes P450 and phase II enzymes. Carcinogen 1996; 17(4)821–828
   PubMed Web of Science ®Google Scholar
• Barch D. H., Rundhaugen L. M., Thomas P. E., Kardos P. Dietary ellagic acid inhibits the enzymatic activity of CYP1A1 without altering hepatic concentrations of CYP1A1 or CYP1A1 mRNA. Biochem. and Biophys. Res. Commun. 1994; 201(3)1477–1482
   PubMed Web of Science ®Google Scholar
• Barch D. H., Rundhaugen L. M. Ellagic acid induces NAD(P)H:quinone reductase gene. Carcinogen 1994; 15(9)2065–2068
   PubMed Web of Science ®Google Scholar
• van Lieshout E. M.M., Bedaf M. M.G., Pieter M., Ekkel C., Nijoff W. A., Peters W. H.M. Effects of dietary anticarcinogens on rat gastrointestinal glutathione S‐transferase theta 1‐1 levels. Carcinogen 1998; 19(11)2055–2057
   PubMedGoogle Scholar
• Dixit R., Gold B. Inhibition of N‐methyl‐N‐nitrosourea‐induced mutagenicity and DNA methylation by ellagic acid. Proc. Natl. Acad. Sci. USA 1986; 83: 8039–8043
   PubMed Web of Science ®Google Scholar
• Barch D. H., Fox C. C. Selective inhibition of methylbenzylnitrosamine‐induced formation of esophageal O6‐methylguanine by dietary ellagic acid in rats. Cancer Res. 1988; 48: 7088–7092
   PubMed Web of Science ®Google Scholar
• Narayanan B. A., Geoffroy O., Willingham M. C., Re G. G., Nixon D. W. P53/p21 (WAF1/CIP1) expression and its possible role in G1 arrest and apoptosis in ellagic acid treated cancer cells. Cancer Lett. 1999; 136: 215–221
   PubMed Web of Science ®Google Scholar
• Soni K. B., Lahiri M., Chackradio P., Bhide S. V., Kuttan R. Protective effect of food additives on aflatoxin‐induced mutagenicity and hepatocarcinogenicity. Cancer Lett. 1997; 115: 129–133
   PubMed Web of Science ®Google Scholar
• Kaul A., Khanduja K. L. Plant polyphenols inhibit benzoyl peroxide‐induced superoxide anion radical production and diacylglyceride formation I murine peritoneal macrophages. Nutr. Cancer. 1999; 35(2)207–211
   PubMed Web of Science ®Google Scholar
• Bock P. E., Srinivasan K. R., Shore J. D. Activation of intrinsic blood coagulation by ellagic acid: insoluble ellagic acid‐metal ion complexes are the activating species. Biochemistry 1981; 20: 7258–7263
   PubMed Web of Science ®Google Scholar
• Dow R. L., Chou T. T., Bechle B. M., Goddard C., Larson E. R. Identification of tricyclic analogs related to ellagic acid as potent/selective tyrosine protein kinase inhibitors. J. Med. Chem. 1994; 37: 2224–2231
   PubMedGoogle Scholar
• Ahmed S., Rahman A., Saleem M., Athar M., Sultana S. Ellagic acid ameliorates nickel induced biochemical alterations: diminution of oxidative stress. Human Exp. Toxicol. 1999; 18: 691–698
   PubMed Web of Science ®Google Scholar
• Katiyar S. K., Challa A., McCormick T. S., Cooper K. D., Mukhtar H. Prevention of UVB‐induced immunosuppression in mice by the green tea polyphenol (−)‐epigallocatechin‐3‐gallate may be associated with alterations in IL‐10 and IL‐12 production. Carcinogen 1999; 20(11)2117–2124
   PubMedGoogle Scholar
• Katiyar S. K., Elmets C. A., Agarwal R., Mukhtar H. Protection against ultraviolet‐B radiation‐induced local and systemic suppression of contact hypersensitivity and edema responses in C3H/HeN mice by green tea polyphenols. Photochem. Photobiol. 1995; 62(5)855–861
   PubMedGoogle Scholar
• Bhargava U. C., Westfall B. A., Siehr D. J. Preliminary pharmacology of ellagic acid from Juglans nigra (black walnut). J. Pharm. Sci. 1968; 57: 1728–1732
   PubMedGoogle Scholar
• Duke S. S., Schook L. B., Holsapple M. P. Effects of N‐nitrosodimethylamine on tumor susceptibility. J. Leuk. Biol. 1985; 37: 383–394
   PubMed Web of Science ®Google Scholar
• Bryant J., Day R., Whiteside T. L., Herberman R. B. Calculation of lytic units for the expression of cell‐mediated cytotoxicity. J. of Immunol. Methods 1992; 146: 91–103
   PubMed Web of Science ®Google Scholar
• Murray M. J., Lauer L. D., Luster M. I., Luebke R. W., Adams D. O., Dean J. H. Correlation of murine susceptibility to tumor, parasite, and bacterial challenge with altered cell‐mediated immunity following systemic exposure to the tumor promoter phorbol myristate acetate. Int. J. Immunopharmacol. 1985; 7: 491–500
   PubMed Web of Science ®Google Scholar
• Jerne N. K., Nordin A. A. Plaque formation in agar by single antibody producing cells. Science 1963; 140: 405
   Web of Science ®Google Scholar
• Cunningham A. J., Szenberg A. Further improvements in the plaque forming technique for detecting single antibody forming cells. Immunol. 1968; 14: 599–601
   PubMed Web of Science ®Google Scholar
• Mukhtar H., Das M., Del Tito B. J., Jr., BickBickers D. R. Protection against 3‐methylcholanthrene‐induced skin tumorigenesis in BALB/C mice by ellagic acid. Biochem. and Biophys. Res. Commun. 1984; 119(2)751–757
   PubMedGoogle Scholar
• Wargovich M. J. Experimental evidence for cancer preventive elements in foods. Cancer Lett. 1997; 114: 11–17
   PubMed Web of Science ®Google Scholar
• Mandal S., Stoner G. D. Inhibition of N‐nitrosobenzylmethylamine‐induced esophageal tumorigenesis in rats by ellagic acid. Carcinogen 1990; 11(1)55–61
   PubMedGoogle Scholar
• Stoner G. D., Morse M. A. Isothiocyanates and plant polyphenols as inhibitors of lung and esophageal cancer. Cancer Lett. 1997; 114: 113–119
   PubMed Web of Science ®Google Scholar
• Doyle B., Griffiths L. A. The metabolism of ellagic acid in the rat. Xenobiotica 1980; 10(4)247–256
   PubMed Web of Science ®Google Scholar
• Lawson P. T. Rats. Assistant Laboratory Animal Technician Training Manual, P. T. Lawson. American Association for Laboratory Animal Science, Chelsea, MI 1998; 112
   Google Scholar
• Calabrese E. J. Overcompensation stimulation: a mechanism for hormetic effects. Crit. Rev. Toxicol. 2001; 31(4–5)425–470
   PubMed Web of Science ®Google Scholar
• Rook A. H., Zaki M. H., Wysocka M., Wood G. S., Duvic M., Showe L. C., Foss F., Shapiro M., Kuzel T. M., Olsen E. A., Vonderheid E. C., Laliberte R., Sherman M. L. The role for interleukin‐12 therapy of cutaneous T cell lymphoma. Ann. N.Y. Acad. Sci. 2001; 941: 177–184
   PubMed Web of Science ®Google Scholar
• Imai N., Harashima N., Ito M., Miyagi Y., Harada M., Yamada A., Itoh K. Identification of Lck‐derived peptides capable of inducing HLA‐A2‐restricted and tumor‐specific CTLs in cancer patients with distant metastases. Int. J. Cancer 2001; 94(2)237–242
   PubMedGoogle Scholar
• Barouch D. H., Letvin N. L. CD8 + cytotoxic T lymphocyte responses to lentiviruses and herpesviruses. Curr. Opin. Immunol. 2001; 13(4)479–482
   PubMedGoogle Scholar
• Baldridge J. R., Barry R. A., Hinrichs D. J. Expression of systemic protection and delayed‐type hypersensitivity to Listeria monocytogenes is mediated by different T‐cell subsets. Infect. Immun. 1990; 58: 654–658
   PubMedGoogle Scholar
• Boes M. Role of natural and immune IgM antibodies in immune responses. [Review] Mol. Immunol. 2000; 37(18)1141–1149
   Google Scholar
• Bachmann M. F., Kopf M. The role of B cells in acute and chronic infections. Cur. Opin. Immunol. 1999; 11(3)332–339
   PubMedGoogle Scholar
• Klasse P. J., Sattentau Q. J. Mechanisms of virus neutralization by antibody. Curr. Top. Microbiol. Immunol. 2001; 260: 87–108
   PubMedGoogle Scholar
• Blackwell N. M., Else K. J. B cells and antibodies are required for resistance to the parasitic gastrointestinal nematode Trichuris muris. Infection & Immunity 2001; 69(6)3860–3868
   PubMedGoogle Scholar
• Planelles L., Thomas M. C., Alonso C., Lopez M. C. DNA immunization with Trypanosoma cruzi HSP70 fused to the KMP11 protein elicits a cytotoxic and humoral immune response against the antigen and leads to protection. Infect. Immun. 2001; 69(10)6558–6563
   PubMedGoogle Scholar