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Immunopharmacology and Immunotoxicology Volume 27, 2005 - Issue 1
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Research Article

Severe Cholestatic Hepatitis Caused by Azathioprine

Dr. Christoph Eisenbach Department of Gastroenterology, Infectious Diseases and Intoxications, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg, Germany, D-69120; Department of Gastroenterology, Infectious Diseases and Intoxications, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg, Germany, D-69120
,
Christoph Goeggelmann Department of Clinical Pharmacology and Pharmacoepidemiology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg, Germany, D-69120
,
Christa Flechtenmacher Department of Pathology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg, Germany, D-69120
,
Wolfgang Stremmel Department of Gastroenterology, Infectious Diseases and Intoxications, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg, Germany, D-69120
&
Jens Encke Department of Gastroenterology, Infectious Diseases and Intoxications, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg, Germany, D-69120
Pages 77-83 | Published online: 08 Oct 2008

References

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  • Romagnuolo, J.; Sadowski, D. C.; Lalor, E.; Jewell, L.; Thomson, A.B. Cholestatic hepatocellular injury with azathioprine: a case report and review of the mechanisms of hepatotoxicity. Can. J. Gastroenterol. 1998, 12 (7), 479–483. [PUBMED], [INFOTRIEVE], [CSA]
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  • Ramalho, H.J.; Terra, E.G.; Cartapatti, E.; Barberato, J.B.; Alves, V.A.; Gayotto, L.C.; Abbud-Filho, M. Hepatotoxicity of azathioprine in renal transplant recipients. Transplant. Proc. 1989, 21 (1 Pt 2), 1716–1717. [PUBMED], [INFOTRIEVE]
  • Small, P.; Lichter, M. Probable azathioprine hepatotoxicity: a case report. Ann. Allergy 1989, 62 (6), 518–520. [PUBMED], [INFOTRIEVE], [CSA]
  • Horsmans, Y.; Rahier, J.; Geubel, A. P. Reversible cholestasis with bile duct injury following azathioprine therapy. A case report. Liver 1991, 11 (2), 89–93. [PUBMED], [INFOTRIEVE]
  • Ramrakhiani, S.; Brunt, E. M.; Bacon, B.R. Possible cholestatic injury from ranitidine with a review of the literature. Am. J. Gastroenterol. 1998, 93 (5), 822–826. [PUBMED], [INFOTRIEVE]
  • Liberopoulos, E. N.; Nonni, A.B.; Tsianos, E.V.; Elisaf, M.S. Possible ranitidine-induced cholestatic jaundice. Ann. Pharmacother. 2002, 36 (1), 172, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]

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