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Journal of Asthma Volume 38, 2001 - Issue 4
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Original

Effects of Suplatast Tosilate on Airway Inflammation and Airway Hyperresponsiveness

Takahiko Horiguchi Department of Internal Medicine, Fujita Health University School of Medicine, Second Educational Hospital, Aichi, Japan
,
Soichi Tachikawa Department of Internal Medicine, Fujita Health University School of Medicine, Second Educational Hospital, Aichi, Japan
,
Misuzu Handa Department of Internal Medicine, Fujita Health University School of Medicine, Second Educational Hospital, Aichi, Japan
,
Kimihiko Hanazono Department of Internal Medicine, Fujita Health University School of Medicine, Second Educational Hospital, Aichi, Japan
,
Rieko Kondo Department of Internal Medicine, Fujita Health University School of Medicine, Second Educational Hospital, Aichi, Japan
,
Akinori Ishibashi Department of Internal Medicine, Fujita Health University School of Medicine, Second Educational Hospital, Aichi, Japan
&
Kengo Banno Department of Internal Medicine, Fujita Health University School of Medicine, Second Educational Hospital, Aichi, Japan
 show all
Pages 331-336 | Published online: 30 Jun 2001

REFERENCES

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  • Yanagihara Y., et al. Suppression of IgE Production by IPD-1151T (Suplatast Tosilate), a New Dimethylsulfonium Agent: 1. Regulation of Murine IgE Response. Jap. J. Pharmacol. 1993; 61: 23
  • Yanagihara Y., et al. Suppression of IgE Production by IPD-1151T (Suplatast Tosilate), a New Dimethylsulfonium Agent: 2. Regulation of Human IgE Response. Jap. J. Pharmacol. 1993; 61: 31
  • Yamaya H., et al. Down-Regulation of Th2 Cell-Mediated Murine Peritoneal Eosinophilia by Anti-Allergic Agents. Life Sci. 1995; 56: 1647
  • Oda N., et al. Effect of Suplatast Tosilate (IPD-1151T) on Cytokine Production by Allergen-Specific Human Th1 and Th2 Cell Lines. Life Sci. 1999; 65: 763
  • Taniguchi H., et al. Suplatast Tosilate, a New Type of Antiallergic Agent, Prevents the Expression of Airway Hyperresponsiveness in Guinea Pigs. Eur. J. Pharmacol. 1996; 318: 447
  • Iijima H., et al. Suplatast Tosilate Inhibits Late Response and Airway Inflammation in Sensitized Guinea Pigs. Am. J. Respir. Crit. Care Med. 1999; 160: 331
  • Takishima T., et al. Direct-Writing Recorder of the Dose-Response Curves of the Airway to Methacholine. Chest 1981; 80: 600
  • Pin J., Gibson P. G., Kolendowicz, et al. Use of Induced Sputum Cell Counts to Investigate Airway Inflammation in Asthma. Thorax 1992; 47: 25
  • Mosmann T. R., Schumacher J. H., Street N. F., et al. Diversity of Cytokine Synthesis and Function of Mouse CD4+T Cells. Immunol. Rev. 1991; 123: 209
  • Matsuura N., et al. Effect of Suplatast Tosilate (IPD-1151T) on types I–IV Allergic Reactions. Folia Pharmacol. Japon. 1992; 100: 495
  • Matsuura N., et al. An Immunopharmacological Study of (±)-[2-[4-(3-ethoxy-2-Hydroxypropoxy)Phenylcarba- moyl]Ethyl]Dimethylsulfoniump-Toluenesulfonate (Suplatast Tosilate, IPD-1151T): I. Effect of IPD-1151T on IgE Antibody Formation in Mice and Rats. Jpn. Pharmacol. Ther. 1994; 22: 1369
  • Sano Y., et al. Anti-inflammatory Effect of Suplatast Tosilate on Mild Asthma. Chest 1997; 112: 862

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